CN1088370C

CN1088370C - Tongguanshugan ointment and preparation process thereof

Info

Publication number: CN1088370C
Application number: CN98104834A
Authority: CN
Inventors: 韩钰
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-01-15
Filing date: 1998-01-15
Publication date: 2002-07-31
Anticipated expiration: 2018-01-15
Also published as: CN1223127A

Abstract

The present invention relates to a plaster capable of curing hepatic diseases by dredging stagnation and soothing the liver. A raw plaster and a prepared plaster are prepared by using traditional Chinese medicines as raw materials. The purpose of curing hepatic diseases can be achieved by successively applying the plasters on hepatic regions. The medicine relieves the pain of taking medicines for patients, and is also convenient for the infiltration of the medicines in order to have better therapeutic effect.

Description

Tongguanshugan ointment and preparation method

The present invention relates to a kind of medicine for the treatment of the hepatitis disease, is the medicine of feedstock production with Chinese medicine specifically, the invention still further relates to the preparation method of this medicine.

Hepatopathy is a kind of disease of serious harm human health, and it not only has infectiousness, and should not cure, and therefore suffers from this sick people and not only self agonizes, and bring very big mental burden to the people around.

For treating this disease, now existing many medical personnels work hard for it, except that the medicine of having sold on the market, a kind of collocation method of Antiheptitic " Ganyanling " has been announced in patent application 91106266 and 91109404 respectively, and preparation of oral liquor for quick curing hepatitis, these two kinds of medicines all are that raw material processes medicine with the Chinese herbal medicine, and they all have certain curative effect, but are oral drugs.

The purpose of this invention is to provide and a kind ofly can directly act on the hepatic region, can remove the external used medicine of the strong treatment hepatopathy of hardship that patient takes medicine and penetration from.

Another object of the present invention provides the preparation method of this medicine.

Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to hepatopathy, achievement with reference to modern pharmacological research, from the Chinese medicine treasure-house, filter out and have strengthening the body resistance, removing heat from blood and promoting blood circulation, the yin nourishing of regulating the flow of vital energy, clearing away heat-damp and promoting diuresis, it is eliminating evil to detoxify, the natural drug of eliminating turbid pathogen with aromatics is formed, and distinctive processing technology in addition, and manufacturing forms.

The present invention is prepared from (consumption is a weight portion) by following medicine components:

Moschus 0.5-5 part Calculus Bovis 0.3-3 part

Resina Ferulae 10-67.5 part Sanguis Draxonis 10-67.5 part

Fructus Crotonis 7.5-60 part Semen Sinapis Albae 15-80 part

Fructus Amomi 1.5-9 part Radix Bupleuri 20-80 part

Herba Artemisiae Scopariae 20-80 part milk 84-496 part

The formula optimization weight portion ratio range of preparation medicine of the present invention is:

Moschus 0.8-3 part Calculus Bovis 0.5-2 part

Resina Ferulae 10-45 part Sanguis Draxonis 10-45 part

Fructus Crotonis 10-37.5 part Semen Sinapis Albae 20-50 part

Fructus Amomi 1.5-7 part Radix Bupleuri 25-70 part

Herba Artemisiae Scopariae 25-65 part milk 102-359 part

Above-mentioned each component is made this medicine production method is:

(1) Moschus, the bovine calculus powder of getting defined amount in the prescription is broken into the fine powder that can cross the 100-120 mesh sieve.

(2) get the Fructus Crotonis of ormal weight in the prescription, Bai Ren is continued to employ in its peeling, take by weighing Resina Ferulae, Sanguis Draxonis, Semen Sinapis Albae, Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription again, these medicines are crushed to jointly the fine powder that can cross the 100-120 mesh sieve.

(3) fine powder that is processed into for twice is lumped together, and mix homogeneously.

(4) be split on the cloth after modulating evenly with the milk in the dosage above-mentioned medicated powder cure use to patient before, make plaster, the drug weight of every plaster is the 100-200 gram, and medicine spreads diameter 10-15 centimetre.

The used milk of plaster Chinese medicine modulation is with people's the best of suckling.

Earlier clear up the hepatic region during treatment, again the plaster of making is applied, used 4-8 hour with Rhizoma Zingiberis Recens, the medicine of exhausted plaster can add milk and repeat reuse, to patient's continuous use time be 8 days, then had a rest seven days, every two weeks is a course of treatment, grasps the number course of treatment that needs treatment according to the state of an illness.

Therefore adopt this kind Drug therapy hepatopathy, removed the hardship that patient takes medicine from, medicine directly is affixed on the hepatic region of clearing up through Rhizoma Zingiberis Recens, is convenient to the infiltration of medicine and to the treatment of hepatopathy.

In order to show the therapeutic effect of the present invention to hepatopathy, from 1992-1997 the present invention 1523 routine patients have been carried out clinical observation, male patient 1297 people wherein, female patient 226 people, by age be grouped into: 53 people below 20 years old, 21-35 year 428 people, 36-50 year 409 people, 51-60 year 320 people, 313 people more than 60 years old; Be grouped into by medical history: the patient below 8 years is 789 people, and the patient of 8-15 is 624 people, and the patient is 110 people more than 15 years; Be grouped into by sick type: first type 189 people, B-mode 1229 people, non-first, non-B-mode 109 people.The patient that above-mentioned patient is examination in hospital, makes a definite diagnosis.

The medicine of other any treatment hepatopathys of stopping using during the treatment only pastes and uses drug prepared of the present invention.

The treatment situation is:

Liver disease types	The first type	B-mode	Non-first, B-mode
Liver disease types	The first type	B-mode	Non-first, B-mode	Treatment number (people)	187	1229	109
Obvious effective rate	99％	98％	97％	Treatment number (people)	187	1229	109
Obvious effective rate	99％	98％	97％	Cure rate	98％	90％	93％

The treatment standard is:

1, disease disappears.

2, the hepatic region does not have tenderness or percussion pain.

3, the Inspection Certificate liver function recovery is normal.

4, hepatitis b liver disease patient HBeAg turns out cloudy.

Above-mentioned patient is carried out in the therapeutic process, after using the present invention 5 courses of treatment,, draws patient's inquiry: all patients no longer include weak, feel sick, detest subjective symptomss such as oil, abdominal distention, hepatalgia, the diet sleep recovers normal.

Embodiment 1:

Take by weighing raw material by following prescription and dosage:

0.3 kilogram of 0.5 kilogram of Calculus Bovis of Moschus

4.5 kilograms of 4.5 kilograms of Sanguis Draxonis of Resina Ferulae

7.5 kilograms of 4.5 kilograms of Semen Sinapis Albaes of Fructus Crotonis

8 kilograms of 0.9 kilogram of Radix Bupleuri of Fructus Amomi

36 kilograms of 7.5 kilograms of milk of Herba Artemisiae Scopariae

Make as follows:

Moschus, bovine calculus powder by required amount in the prescription are broken to the fine powder that to cross 100 mesh sieves; get the Fructus Crotonis of required amount in the prescription; Bai Ren is continued to employ in its peeling; take by weighing Resina Ferulae, Sanguis Draxonis, Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of required amount in the prescription; they are crushed to the fine powder that can cross 100 mesh sieves jointly; then the fine powder mix homogeneously that is processed into for twice; the milk of said medicine with amount in the prescription is in harmonious proportion; then spread out on cloth; make plaster; every plaster content of dispersion is 200 grams, and the plaster diameter is 15 centimeters, carries out before use with milk mediation operation.

Embodiment 2: take by weighing raw material by following dosage:

0.2 kilogram of 0.25 kilogram of Calculus Bovis of Moschus

3 kilograms of 3 kilograms of Sanguis Draxonis of Resina Ferulae

4.5 kilograms of 2.5 kilograms of Semen Sinapis Albaes of Fructus Crotonis

4 kilograms of 0.25 kilogram of Radix Bupleuri of Fructus Amomi

2.9 kilograms of people of Herba Artemisiae Scopariae suckle 12 kilograms

Moschus, bovine calculus powder by required amount in the prescription are broken to 120 purpose fine powders; Bai Ren is continued to employ in the peeling of Fructus Crotonis in the prescription; take by weighing the Resina Ferulae and the Sanguis Draxonis of weight in the prescription; take by weighing Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription again; they are crushed to 120 purpose fine powders jointly, and then the fine powder mix homogeneously that is processed into for twice, the powder that said medicine is made is suckled with the people of ormal weight in the prescription and is in harmonious proportion evenly before use; spread out on cloth, making diameter and be 12 centimeters, weight is the plaster of 100 grams.

Claims

1, a kind of Tongguanshugan ointment for the treatment of hepatopathy is characterized in that: medicine that it is contained and consumption weight portion thereof are:

Moschus 0.5-5 part Calculus Bovis 0.3-3 part

Resina Ferulae 10-67.5 part Sanguis Draxonis 10-67.5 part

Fructus Crotonis 7.5-60 part Semen Sinapis Albae 15-80 part

Fructus Amomi 1.5-9 part Radix Bupleuri 20-80 part

Herba Artemisiae Scopariae 20-80 part milk 84-496 part.

2, the Tongguanshugan ointment of treatment hepatopathy according to claim 1 is characterized in that: medicine that it is contained and consumption weight portion are:

Moschus 0.8-3 part Calculus Bovis 0.5-2 part

Resina Ferulae 10-45 part Sanguis Draxonis 10-45 part

Fructus Crotonis 10-37.5 part Semen Sinapis Albae 20-50 part

Fructus Amomi 1.5-7 part Radix Bupleuri 25-70 part

Herba Artemisiae Scopariae 25-65 part milk 102-359 part.

3, a kind of preparation method of Tongguanshugan ointment as claimed in claim 1 or 2 is characterized in that:

A, the Moschus of getting defined weight portion in the prescription, bovine calculus powder are broken to the fine powder that can cross the 100-120 mesh sieve;

B, get the Fructus Crotonis of predetermined weight part in the prescription again, Bai Ren is continued to employ in its peeling, take by weighing Resina Ferulae, Sanguis Draxonis, Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription again, they are crushed to the fine powder that can cross the 100-120 mesh sieve jointly;

C, the fine powder that is processed into for twice is lumped together, and mix homogeneously, cure to patient use before with above-mentioned medicated powder with prescription in the milk of ormal weight modulate, and spread out on cloth, make plaster.

4, according to the preparation method of the described Tongguanshugan ointment of claim 3, it is characterized in that; The weight of every plaster contained drug is the 100-200 gram, and it is the 10-15 centimetre that its plaster medicine spreads diameter.

5, the preparation method of Tongguanshugan ointment according to claim 4 is characterized in that: the used milk of preparation plaster is people's milk.