CN1327831A - Chinese medicine for treating tinea and antipruritic - Google Patents

Abstract

A Chinese medicine for treating tinea, dermatitis, psoriasis, skin ulcer, etc. is prepared from 11 Chinese-medicinal materials including dittany bark, flavescent sophora root, ledebouriella root, phellodendron bark, etc. through proportioning. Its advantages include high curative effect, no toxic by-effect and no recurrence.

Description

A kind of Chinese medicine preparation for the treatment of tinea and antipruritic

The present invention relates to the dermopathic Chinese medicine preparation of a kind of treatment, clear and definite saying is the Chinese medicine preparation that discloses a kind for the treatment of tinea and antipruritic, belongs to traditional Chinese medical science pharmaceutical technology field.

The medicine of treatment tinea has much at present, generally adopt Therapeutic Method such as hormones antiallergic, but curative effect is very imprecise mostly, cures the symptoms, not the disease, and dependency is strong, and outbreak repeatedly has some medicines to have very big zest and toxic and side effects after the drug withdrawal.

The present invention discloses a kind of Chinese medicine preparation of controlling tinea and relieving itching, treating both the principal and secondary aspects of a disease, and nonirritant, toxic and side effects is very little.

The technology of the present invention solution is according to understanding and the Therapeutic Principle of tcm theory to the pathogenesis of tinea, with reference to modern medical theory, from the medical treasure-house of motherland, choose and have anti-inflammation, killing parasites for relieving itching, heat-clearing and toxic substances removing is subsided a swelling and is ended the pure herbal raw material of effects such as pus, makes Chinese medicine preparation through the science processing procedure.

Chinese medicine preparation of the present invention by following raw materials by weight portion than making:

Favus skin 25～35, Radix Sophorae Flavescentis 18～22, Radix Saposhnikoviae 12～18, Herba speranskiae tuberculatae 25～35,

Cortex erythrinae 12～18, Cortex Phellodendri 18～22, Fructus Cnidii 25～35, Alumen 18～22,

Rhizoma Polygonati 25～35, Herba Pogostemonis 25～35.

Optimum ratio of the present invention is (parts by weight):

Favus skin 30, Radix Sophorae Flavescentis 20, Radix Saposhnikoviae 15, Herba speranskiae tuberculatae 30, Cortex erythrinae 15,

Cortex Phellodendri 20, Fructus Cnidii 30, Alumen 20, Rhizoma Polygonati 30, Herba Pogostemonis 30.

Processing procedure: get above-mentioned raw materials selected, dry, be ground into 80～100 order fine powders, add glacial acetic acid and soak, addition get final product not there not to be raw material, room temperature soaked 15～20 days down, the leaching soak, make tincture.Also filtrate can be concentrated into relative density is 1.20～1.25 (50 ℃), adds matrix oil vaseline furnishing ointment preparation.

Have pathogenic fire purging dehumidifying, killing parasites for relieving itching, heat-clearing toxin-expelling functions at favus skin of the present invention, Radix Sophorae Flavescentis; Radix Saposhnikoviae, Herba speranskiae tuberculatae, Cortex erythrinae are delivered and are dispeled the wind, and win and wet, the detoxifcation pain relieving; Cortex Phellodendri, Fructus Cnidii, Alumen clearing away heat and cooling blood, the poison holding skin ulcer that disappears, heat clearing and damp drying, nourishing YIN to lower pathogenic fire, damp eliminating parasite killing; Rhizoma Polygonati, Herba Pogostemonis spleen reinforcing intestine moistening, removing dampness by means of aromatics, expelling summer-heat, assistant is not coagulated so that bitter and cold medicines is cool with vinegar essence dissipating blood stasis blood, detumescence pain, plays the effect of heat clearing and damp drying killing parasites for relieving itching altogether.

Instructions of taking: the coating of usual amounts affected part, every day 2～3 times.

Characteristics of the present invention are: pure Chinese herbal medicine is made, no hormone, and toxic and side effects is little, and treating both the principal and secondary aspects of a disease is evident in efficacy, and clinical symptom disappearance is rapid, does not have drug dependence, cures the no rebound phenomena in back.Be applicable to diseases such as all kinds dermatitis, tinea, tinea cruris, tinea manus and pedis, psoriasis, skin ulcer, infection, scabies, skin pruritus.

For showing the therapeutical effect of the present invention, carry out clinical observation by medicine of the present invention to tinea:

One, the diagnostic criteria of disease: the clinical manifestation symptom according to tinea is divided into

1, homeliness type: for red pimple, coin shape, map shape, refer to that the toenail mucosa can get involved.

2, fester type: occur on the homeliness type tinea skin, also can occur on the normal skin, the heat that often occurs together, several fingernails of General Symptomies such as arthralgia and swelling change.

3, arthritis type: general with the fester type and deposit, the ectype tinea also long afterwards, the arthritis that also occurs together pathological changes.

4, erythrodermic: psoriasis irriate or deal with improperly and form, show as whole skin diffusivity redness, a large amount of silver bits are arranged.

Two, case is selected:

Select homeliness type, fester type according to clinical symptoms, as main body, be coated with respectively and use medicine of the present invention, every day 2～3 times with these two kinds of sick type patients.

Three, grouping and comprehensive medication: for the ease of the contrast of curative effect degree, the patient is divided into test group and matched group, test group adopts medicine coating of the present invention affected part, every day 2～3 times; Matched group is selected fluocinonide ointment for use, by its illustration method treatment.

Test group is selected 147 examples, 20～40 years old 96 people wherein, 40～60 years old 51 example, male's 98 examples, women's 49 examples, homeliness type 81 examples, fester type 66 examples.

Four, experimental technique:

1, medical record: set up medical record for test group and matched group on request.

2, treatment time and inspection item:

The homeliness type patient 20 days was a course of treatment, general 2～3 courses of treatment.

Fester type patient 30 days was a course of treatment, 4～5 courses of treatment.

All patients make regular check on the treatment situation in therapeutic process, finish the back course of treatment and do to check comprehensively.

Five, curative effect is judged:

1, recovery from illness: scytitis disappears, and still keeps normal level after the drug withdrawal in one month.

2, effective: scytitis disappears behind the coating, reaches normal condition.

2, produce effects: itch behind the coating, consider to be worth doing, the red and swollen disappearance, the still conscious pain of slightly itching.

3, invalid: ringworm goes down very for a short time behind the coating, and symptom is constant.

Six, clinical observation result:

147 examples are organized in clinical total effects treatment, clinical cure 68 examples (46.3%), produce effects 42 examples (%28.6), effective 21 examples (14.3), invalid 16 examples (10.8), total effective rate 89.2%.Matched group 128 examples, clinical cure 31 examples (24.2%), produce effects 26 examples (20.3%), effective 19 examples (14.8%), invalid 52 examples (40.7%), total effective rate 59.3%.Two groups relatively, and the treatment group significantly is better than matched group.See the following form:

Group	Clinical cure (%)	Produce effects (%)	Effectively (%)	Invalid (%)	Total effective rate (%)
						Treatment group 147	68(46.3)	42(28.6)	21(14.3)	16(10.8)	89.2
Matched group 128	31(24.2)	26(20.3)	19(14.8)	52(40.7)	59.3

Clinical trial proves that medicine of the present invention is obvious to the treating tinea and antipruritic effect, and stable lasting, the sterilizing and itch-relieving effect is remarkable, and recovery from illness and total effective rate all are better than matched group.

Case 1: Zhao, the man, 59 years old, there were the one 15 centimeters red mound of circle speckles at preceding shank place, and the coin shape is scraped the desquamation of itching, and red damaged, it is invalid to cure for a long time.Use medicine of the present invention recovery from illness in more than 20 day, skin surface is smooth, and color is with identical on every side, and healing did not have bounce-back in back 4 months.

Case 2: Lee, the man, 30 years old, tinea cruris was very itched desquamation for many years, influences orthobiosis.Be coated with and use medicine of the present invention 30 days, the desquamation transference cure of scratching where it itches, the colour of skin to recover normal, no vestige does not have repeatedly so far.

Case 3: Zhu, the woman, 68 years old, suffer from the tinea pedis more than two decades, clinical symptoms is for very itching unbearably, use multiple treatment way during this time, medicine is produced dependency, medication is alleviated, and end-of-dose failure is very painful, apply 3 courses of treatment of medicine of the present invention, recovery from illness, clinical symptom disappearance, drug withdrawal did not have recurrence in 1 year.

Further specify the present invention below in conjunction with embodiment:

Embodiment 1:

Get favus skin 30g, Radix Sophorae Flavescentis 20g, Radix Saposhnikoviae 15g, Herba speranskiae tuberculatae 30g, Cortex erythrinae 15g, Cortex Phellodendri 20g, Fructus Cnidii 30g, Alumen 20g, Rhizoma Polygonati 30g, Herba Pogostemonis 30g selected, dry, be ground into 90 order fine powders, adding glacial acetic acid soaks, addition did not get final product there not to be raw material, room temperature soaked 18 days down, cross the leaching soak, make tincture.

Embodiment 2

It is 1.20～1.25 (50 ℃) that embodiment 1 gained soak is concentrated into relative density, adds matrix oil vaseline furnishing ointment preparation.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of tinea and antipruritic is the Chinese medicine preparation of being made by ratio of weight and the number of copies by following material:

Favus skin 25～35, Radix Sophorae Flavescentis 18～22, Radix Saposhnikoviae 12～18, Herba speranskiae tuberculatae 25～35,

Cortex erythrinae 12～18, Cortex Phellodendri 18～22, Fructus Cnidii 25～35, Alumen 18～22,

Rhizoma Polygonati 25～35, Herba Pogostemonis 25～35.

2, the Chinese medicine preparation for the treatment of tinea and antipruritic according to claim 1 is characterized in that: optimum ratio is:

Favus skin 30, Radix Sophorae Flavescentis 20, Radix Saposhnikoviae 15, Herba speranskiae tuberculatae 30, Cortex erythrinae 15,

Cortex Phellodendri 20, Fructus Cnidii 30, Alumen 20, Rhizoma Polygonati 30, Herba Pogostemonis 30.

3, according to claim 1,2 described treating tinea and antipruritic Chinese medicine preparation, it is characterized in that: described dosage form comprises tincture, the unguentum on the pharmaceutics.