CN110496164A - It is a kind of to treat psoriasic Chinese medicine composition and preparation method thereof - Google Patents

It is a kind of to treat psoriasic Chinese medicine composition and preparation method thereof Download PDF

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CN110496164A
CN110496164A CN201910884285.2A CN201910884285A CN110496164A CN 110496164 A CN110496164 A CN 110496164A CN 201910884285 A CN201910884285 A CN 201910884285A CN 110496164 A CN110496164 A CN 110496164A
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周文亮
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
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Abstract

Psoriasic Chinese medicine composition and preparation method thereof is treated the present invention relates to a kind of.The psoriasic Chinese medicine composition for the treatment of is made of 10 parts by weight of radix scutellariae, 10 parts by weight of Cortex Phellodendri, 65 parts by weight of kuh-seng, 15 parts by weight of erythrina bark, 5 parts by weight of rheum officinale, 5 parts by weight of alum, 35 parts by weight of lopseed, 20 parts by weight of the achene of Siberian cocklebur, 35 parts by weight of sweet wormwood.The present invention treats psoriasis significant effect, and antipruritic effect does not recur significantly, and at low cost without side-effects.

Description

It is a kind of to treat psoriasic Chinese medicine composition and preparation method thereof
Technical field
The invention belongs to field of pharmaceutical technology, it is related to a kind for the treatment of psoriasic Chinese medicine composition and preparation method thereof.
Background technique
Ox-hide moss is a kind of common chronic inflammatory dermatoses for being easy to recur with characteristic skin lesion.From the beginning of being scorching Property, bacterium property red papules, about grain grain to copper coin size, being gradually expanded or merge later becomes brownish red patch, and surface covering is more The silver-colored chip of the dry white of layer.Gently scraper surface silver chip is gradually exposed the shinny film bleeding of one layer of pale red, contains Brownish red is flat greatly, also has brownish red bulk protrusion, skin change is split, referred to as psoriasic there are also the symptom of the small fourth of grey in flakes Five kinds of skin characteristics.
Ox-hide moss is a kind of refractory skin for being difficult to cure.Previous treatment ox-hide moss, doctor trained in Western medicine is mainly to take anti-leaf orally Based on acids drug, such as methotrexate, ethyleneimine, bis-morpholine.External drug is mainly steroids.Chinese traditional treatment parting is not One, for comprehensive, mainly use the drug of clearing heat and detoxicating cool blood, such as honeysuckle, Radix Rehmanniae, smilax.It but is mostly short-term Curative effect, and curative effect is difficult to control, and is easy recurrence.Thus bring is treated repeatedly, keeps its patient's medical expense higher, to patient with Carry out spiritual and economic aspect serious burden, disease is also a disease.
Summary of the invention
In view of it is above-mentioned the problems of in the prior art, the present invention provide it is a kind of treat psoriasic Chinese medicine composition and Preparation method, the traditional Chinese medicine composition for treating significant effect, and cost is relatively low is free from side effects.
The present invention provide it is a kind of treat psoriasic Chinese medicine composition, be made of the component of following parts by weight:
10 parts by weight of radix scutellariae；
10 parts by weight of Cortex Phellodendri；
Kuh-seng 60-65 parts by weight；
Erythrina bark 13-15 parts by weight；
5 parts by weight of rheum officinale；
5 parts by weight of alum；
Lopseed 30-35 parts by weight；
20 parts by weight of the achene of Siberian cocklebur；
Sweet wormwood 30-35 parts by weight.
Preferably, it is made of forming for following parts by weight: 10 parts by weight of radix scutellariae, 10 parts by weight of Cortex Phellodendri, 65 parts by weight of kuh-seng, 15 parts by weight of erythrina bark, 5 parts by weight of rheum officinale, 5 parts by weight of alum, 35 parts by weight of lopseed, 20 parts by weight of the achene of Siberian cocklebur, 35 weight of sweet wormwood Measure part.
The present invention also provides a kind of preparation methods for treating psoriasic Chinese medicine composition, comprising the following steps:
Radix scutellariae, Cortex Phellodendri, kuh-seng, erythrina bark, rheum officinale, alum, lopseed, the achene of Siberian cocklebur, sweet wormwood are weighed according to aforementioned proportion；
Bulk pharmaceutical chemicals are put into pot, water infusion is added；
Cease fire after infusion to liquid medicine residue 1/3, and the dregs of a decoction are pulled out.
Beneficial effects of the present invention are as follows:
Compared with prior art, the present invention treats psoriasis significant effect, and antipruritic effect does not recur significantly, and at low cost without pair work With.
Specific embodiment
Technical solution in the embodiment of the present invention carries out clear and complete explanation below.Obviously, described embodiment Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects It encloses.
Psoriasic traditional Chinese liquid medicine is treated the present invention provides a kind of, is made of the component of following parts by weight:
10 parts by weight of radix scutellariae；
10 parts by weight of Cortex Phellodendri；
Kuh-seng 60-65 parts by weight；
Erythrina bark 13-15 parts by weight；
5 parts by weight of rheum officinale；
5 parts by weight of alum；
Lopseed 30-35 parts by weight；
20 parts by weight of the achene of Siberian cocklebur；
Sweet wormwood 30-35 parts by weight.
Wherein, the present invention is not particularly limited all original sources, is commercially available.
Radix scutellariae content is 8g.Radix scutellariae: bitter, it is cold in nature, there is heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention and other effects, use In treatment damp-warm syndrome, summer-heat and damp, chest tightness and emesis, damp and hot feeling of fullness, dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle swells sore The illnesss such as poison, threatened abortion.
Cortex Phellodendri content is 10g.Cortex Phellodendri: bitter, it is cold in nature, return kidney channel, bladder meridian, there are the function such as heat-clearing and damp-drying drug, purging fire for removing toxin Effect, is usually used in damp-heat dysentery, jaundice, quenches one's thirst, leukorrhagia, heat gonorrhea, and aphthae, fistula ward off, hectic fever due to yin, labor heat, night sweat, spermatorrhea, sore The card such as swelling and pain, eczema itch.
The preferred 65g of kuh-seng content.Kuh-seng: bitter, it is cold in nature, return liver, kidney, large intestine, small intestine, bladder, the heart channel of Hang-Shaoyin, has heat-clearing dry Wet, wind dispelling insecticide and other effects is usually used in controlling damp-heat dysentery, hematochezia, jaundice, difficult urination, oedema, leukorrhagia, pruritus vulvae, scabies The card such as tinea, leprosy, pruitus, wet poison sore controls trichomonas vaginitis outside.
The preferred 15g of erythrina bark content.Erythrina bark: nature and flavor, bitter, Xin Xingping have dispelling wind and eliminating dampness, remove obstruction in channels to relieve pain and wait function Effect, for treating the illnesss such as rheumatic arthralgia, psoriasis.
Rheum officinale content is 5g.Rheum officinale: bitter is cold in nature, nontoxic, has and rushes down real heat, broken stagnant, row extravasated blood and other effects, for controlling The effects for the treatment of real heat constipation, hygropyretic jaundice, oedema.
Alum content is 5g.Alum: sour-puckery flavor, cold in nature toxic, distributed in lung channel, Liver Channel, large intestine channel, bladder meridian have dissolving phlegm Eliminating dampness, antidiarrheal, hemostasis, removing toxic substances, desinsection and other effects are usually used in the diseases such as aphthae, sore scabies tinea, water, fire, insect bite.
Lopseed content is 35g.Lopseed: nature,taste and action, acrid flavour is warm-natured, nontoxic, has the function such as the wet, promoting blood circulation and stopping pain of relieve heat Effect, for treating rheumatalgia pain, muscles and bones muscular constricture, eczema of scrotum, paralysis, sore swollen toxin.
Achene of Siberian cocklebur content is 20g.The achene of Siberian cocklebur: acrid-sweet flavor is warm-natured, slightly poisonous, energy inducing diaphoresis relieve heat dehumidifying, for treating headache The illnesss such as nasal obstruction rhinorrhea, rheumatism, numbness pain, sore scabies itch.
Sweet wormwood content is 35g.Sweet wormwood: nature,taste and action, bitter is cold in nature, nontoxic, there is clearind deficient heat, driving away summer heat, hemostasis choleretic effect, For treating tuberculosis fever night sweat, clear heat purges heat, manage labor preventing and curing malaria, controls the illnesss such as hot summer weather epidemic heat syndrome.
Therapeutic effect conspicuousness in order to further illustrate the present invention, is retouched in detail below in conjunction with preparation method embodiment It states.
Embodiment 1:
According to radix scutellariae 10g, Cortex Phellodendri 10g, kuh-seng 60g, erythrina bark 13g, rheum officinale 5g, alum 5g, lopseed 30g, achene of Siberian cocklebur 20g, Sweet wormwood 30g weighs various bulk pharmaceutical chemicals.After bulk pharmaceutical chemicals are respectively put into pot, be added the infusion of 30000g water, infusion to liquid medicine about Remaining 10000g or so pulls the dregs of a decoction out after ceasing fire, and obtain medical treatment psoriasic traditional Chinese liquid medicine, uses container package after cooling.
Embodiment 2:
According to radix scutellariae 10g, Cortex Phellodendri 10g, kuh-seng 65g, erythrina bark 15g, rheum officinale 5g, alum 5g, lopseed 35g, achene of Siberian cocklebur 20g, Sweet wormwood 35g weighs various bulk pharmaceutical chemicals.After bulk pharmaceutical chemicals are respectively put into pot, be added the infusion of 30000g water, infusion to liquid medicine about Remaining 10000g or so pulls the dregs of a decoction out after ceasing fire, and obtain medical treatment psoriasic traditional Chinese liquid medicine, uses container package after cooling.
Comparative example 1:
Radix scutellariae 5g, Cortex Phellodendri 5g, kuh-seng 10g, erythrina bark 10g, achene of Siberian cocklebur 10g, rheum officinale 3g, alum 2g weigh various bulk pharmaceutical chemicals.It will After bulk pharmaceutical chemicals are respectively put into pot, water infusion is added and obtains liquid medicine.
Traditional Chinese liquid medicine will be obtained in traditional Chinese liquid medicine obtained in comparative example 1 and embodiment 1 carries out treatment psoriasis drug effect ratio Compared with as the result is shown: liquid medicine obtained in comparative example 1, which is applied to behind affected part, not to be felt, affected part is not obviously improved；In embodiment 1 After obtained liquid medicine is applied to affected part, antipruritic effect is played and that repeatedly, affected part scurf does not thoroughly fall off, and there are also general for skin surface Red inflammatory symptom plays affected part 80% effect.
Comparative example 2:
Radix scutellariae 5g, Cortex Phellodendri 5g, kuh-seng 15g, erythrina bark 15g, rheum officinale 3g, alum 3g, duckweed 5g weigh various bulk pharmaceutical chemicals.By raw material After medicine is respectively put into pot, water infusion is added and obtains liquid medicine.
Traditional Chinese liquid medicine will be obtained in traditional Chinese liquid medicine obtained in comparative example 2 and embodiment 2 carries out treatment psoriasis drug effect ratio Compared with as the result is shown: after liquid medicine obtained in comparative example 2 is applied to affected part, playing antipruritic effect at that time, there is scabies after 12 hours later again Gargalesthesia plays affected part 10% effect；After liquid medicine obtained in embodiment 2 is applied to affected part, plays antipruritic effect and do not have Repeatedly, affected part scurf thoroughly falls off, and skin surface inflammation is eliminated, and 98% effect is played for affected part.
Comparative example 3:
Radix scutellariae 8g, Cortex Phellodendri 8g, kuh-seng 40g, erythrina bark 10g, rheum officinale 4g, alum 4g, lopseed 20g, achene of Siberian cocklebur 15g, sweet wormwood 20g Various bulk pharmaceutical chemicals are weighed, after bulk pharmaceutical chemicals are respectively put into pot, water infusion is added and obtains liquid medicine.
Traditional Chinese liquid medicine will be obtained in traditional Chinese liquid medicine obtained in comparative example 3 and embodiment 2 carries out treatment psoriasis drug effect ratio Compared with as the result is shown: after being applied to affected part obtained in comparative example 3, playing antipruritic effect, have scratchiness again after 24 hours later, suffer from Place's scurf, which has, to fall off, and relatively thin psoriasis occurs after spending 36 hours, 50% effect is played for affected part；Medicine obtained in embodiment 2 After water is applied to affected part, playing antipruritic effect and do not have repeatedly, affected part scurf thoroughly falls off, and skin surface inflammation is eliminated, for Play 98% effect in affected part.
In addition, utilizing the treatment course and its detailed process of liquid medicine of the present invention treatment ox-hide moss: moderate patient treats, liquid medicine Number is 60-80 times；Severe patient treatment, liquid medicine number are 100-120 times；Severe patient treatment, liquid medicine number are 140- 160 times.Drug dose is lower, moderate cost at low cost.
Above-mentioned comparative example shows traditional Chinese medicine composition for treating psoriasis significant effect provided by the invention.In addition, the present invention mentions The Chinese medicine composition of confession equally has to eczema, all kinds of skin diseases such as morbilli and has good therapeutic effect.

Claims (3)

1. a kind of treat psoriasic Chinese medicine composition, which is characterized in that be made of the component of following parts by weight:
10 parts by weight of radix scutellariae；
10 parts by weight of Cortex Phellodendri；
Kuh-seng 60-65 parts by weight；
Erythrina bark 13-15 parts by weight；
5 parts by weight of rheum officinale；
5 parts by weight of alum；
Lopseed 30-35 parts by weight；
20 parts by weight of the achene of Siberian cocklebur；
Sweet wormwood 30-35 parts by weight.
2. the psoriasic Chinese medicine composition for the treatment of according to claim 1, which is characterized in that by forming for following parts by weight It is made: 10 parts by weight of radix scutellariae, 10 parts by weight of Cortex Phellodendri, 65 parts by weight of kuh-seng, 15 parts by weight of erythrina bark, 5 parts by weight of rheum officinale, alum 5 Parts by weight, 35 parts by weight of lopseed, 20 parts by weight of the achene of Siberian cocklebur, 35 parts by weight of sweet wormwood.
3. a kind of preparation method for treating psoriasic Chinese medicine composition characterized by comprising
Ratio described in accordance with the claim 1 weighs radix scutellariae, Cortex Phellodendri, kuh-seng, erythrina bark, rheum officinale, alum, lopseed, the achene of Siberian cocklebur, Sweet wormwood；
Bulk pharmaceutical chemicals are put into pot, water infusion is added；
Cease fire after infusion to liquid medicine residue 1/3, and the dregs of a decoction are pulled out.
CN201910884285.2A 2019-09-19 2019-09-19 It is a kind of to treat psoriasic Chinese medicine composition and preparation method thereof Pending CN110496164A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327831A (en) * 2001-06-15 2001-12-26 姜莉蔚 Chinese medicine for treating tinea and antipruritic
CN102727798A (en) * 2011-03-31 2012-10-17 吕维学 Traditional Chinese medicine for treating psoriasis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327831A (en) * 2001-06-15 2001-12-26 姜莉蔚 Chinese medicine for treating tinea and antipruritic
CN102727798A (en) * 2011-03-31 2012-10-17 吕维学 Traditional Chinese medicine for treating psoriasis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
林中: "银屑病", 《广西中医药》 *
王铸等: "中医辨证治疗寻常型银屑病126例", 《河南中医》 *

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