CN105560858A - Traditional Chinese medicinal composition for treating peptic ulcer - Google Patents

Traditional Chinese medicinal composition for treating peptic ulcer Download PDF

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CN105560858A
CN105560858A CN201511017420.1A CN201511017420A CN105560858A CN 105560858 A CN105560858 A CN 105560858A CN 201511017420 A CN201511017420 A CN 201511017420A CN 105560858 A CN105560858 A CN 105560858A
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herba
radix
peptic ulcer
chinese medicine
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刘富刚
冯复利
林枫
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating peptic ulcer. The composition comprises, by weight, 3-6 parts of Flos Citri Sarcodactylis, 5-10 parts of mandarin orange leaf, 5-10 parts of birchleaf pear branchlet and leaf, 3-5 parts of Torenia fournieri Lind, 2-5 parts of Dregea volubilis, 3-7 parts of fruit of Abelmoschus sagittifolius (Kurz) Merr., 8-15 parts of white backleaf mallotus root, 5-12 parts of Root of Common Butterbush, 3-7 parts of Aeschynanthus acuminatus Wall., 3-7 parts of Herb of Common Vetch, 2-5 parts of Thymus quinquecostatus, 5-15 parts of cow pea root, 5-12 parts of Adenia chevali, 8-15 parts of Crepis phoenix Dunn, 3-8 parts of root of Polygonum hydropiper and 5-15 parts of Bulbophyllum Inconspicuum Maxim. The traditional Chinese medicinal composition has the efficacy of coursing liver and harmonizing stomach, clearing heat and draining dampness, removing blood stasis and relieving pains, invigorating spleen and strengthening mid-energy, and nourishing yin and stomach, and has the advantages of effective treatment of the peptic ulcer, definite therapeutic effect, difficult recurrence and no toxic or side effects.

Description

A kind of Chinese medicine composition for the treatment of peptic ulcer
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of peptic ulcer.
Background technology
Peptic ulcer mainly refers to betide the duodenal chronic ulcer of harmonization of the stomach, is a frequently-occurring disease, commonly encountered diseases.Ulcer be formed with various factors, wherein the Digestion of acidic gastric juice to mucosa is the Fundamentals of ulcer, hence obtains one's name.Any position of acidic gastric juice contact, as distal esophagus, the postoperative anastomotic stoma of gastrointestinal anastomosis, jejunum and the Meckel diverticulum with ectopic gastric mucosa.Most ulcer betides duodenum stomach function regulating, therefore also known as taste-blindness rate.
Epigastrium pain is one of modal symptom of Peptic Ulcers, the common feature having rhythmicity, periodicity and chronicity, the character of pain is often dull pain, causalgia, distending pain, hunger pain or severe pain, based on the medium degree dull pain of paroxysmal, also having persistence dull pain person, can be alkalescent medicine and food respite.The painful area of gastric ulcer is under xiphoid-process or to the left, and duodenal ulcer is then to the right, and rear wall penetrating ulcer pain can be radiated to thoracic vertebra district, back 7 ~ 12.The persistent period of each panic attacks is mostly 1 ~ 2 hour, also the sustainable a few days.The outbreak of pain has seasonality, and most susceptible disease of general time of the year when autumn changes into winter, gastric ulcer pain betides 1/2 ~ 2 hour after the meal, then alleviates after gastric emptying through 1 ~ 2 hour.Its rule is feed-comfortable-pain-comfortable.Duodenal ulcer pain Chang Yu outbreak in 2 ~ 4 hours after meal, continue to next time and just alleviate after feed, its rule is feed-comfortable-pain, and hypnalgia of being everlasting is waken up.The outbreak of peptic ulcer can with symptoms such as belch, acid regurgitation, sialorrhea, Nausea and vomiting.
Peptic ulcer in motherland's medical science " gastric abscess ".Mostly because feelings will is unsuccessful or eating and drinking without temperance causes YANG deficiency of the spleen and stomach, dysfunction of the spleen in transportation and transformation; Or irritability stasis, functional activity of QI being not smooth; Even qi depression to blood stasis, stomach network is obstructed, and produces gastral cavilty portion pain.
At present, the drug main for the treatment of peptic ulcer will comprise the medicine reducing the medicine of gastric acid, the medicine of Eliminating H. pylori Infection by Means and strengthen gastric mucosal protective effect, and curative effect is not easily consolidated, and easily recurs.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition for the treatment of peptic ulcer that a kind of determined curative effect, effective percentage are high, not easily recur.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of peptic ulcer, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 3-6 part, Citrus chachiensis Hort. (C. Suavissima Tanaka) 5-10 part, Ramulus et folium pyri betulaefoliae 5-10 part, blue pig ear 3-5 part, Herba Dregeae volubilis 2-5 part, cannon Fructus Tsaoko 3-7 part, Radix Malloti Apelitae 8-15 part, Radix Cephalanthi Occidentalis 5-12 part, Shi Rong 3-7 part, Herba Viviae Sativae 3-7 part, Herba Thymi 2-5 part, Radix vignae sinensis 5-15 part, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 5-12 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 8-15 part, Radix Polygoni Hydropiperis 3-8 part, Herba Bulbophylli inconspicui 5-15 part.
Preferably, a kind of Chinese medicine composition for the treatment of peptic ulcer, is made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 5 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 8 parts, Ramulus et folium pyri betulaefoliae 5 parts, blue pig ear 5 parts, Herba Dregeae volubilis 4 parts, cannon Fructus Tsaoko 5 parts, Radix Malloti Apelitae 10 parts, Radix Cephalanthi Occidentalis 10 parts, Shi Rong 5 parts, Herba Viviae Sativae 7 parts, Herba Thymi 5 parts, Radix vignae sinensis 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 8 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Radix Polygoni Hydropiperis 5 parts, Herba Bulbophylli inconspicui 10 parts.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Flos Citri Sarcodactylis is flower and the alabastrum of rutaceae Fructus Citri Sarcodactylis, micro-hardship, and tepor, returns liver, stomach warp, depressed liver-energy dispersing and QI regulating; Stomach function regulating soon every.Main stomachache due to hyperactive liver-QI attacking the stomach; Inappetence.
Citrus chachiensis Hort. (C. Suavissima Tanaka) is the leaf of the multiple Citrus chachiensis Hort. classes such as rutaceae Citrus reticulata Blanco cv. Chachiensis or bowl Citrus chachiensis Hort., pungent, bitter, flat, returns spleen, stomach, Liver Channel, circulation of qi promoting the chest stuffiness relieving; Dispersing the stagnated liver-QI for regulating the stomach; Removing toxicity for eliminating carbuncles.Main septum pectorale is full vexed; Distending pain over the hypochondrium; Blockage of menstruation; Diaphragm carbuncle; Acute mastitis; Breast carcinoma.
Ramulus et folium pyri betulaefoliae is the branch and leaf of rosaceous plant Fructus pyri betulaefoliae, acid, sweet puckery, cold, returns large intestine channel, soothing liver-QI stomach function regulating, emergency antidiarrheal.Food is told in main regurgitation, and cholera is vomited and diarrhoea, convulsion stomachache.
Blue pig ear is the herb of Scrophulariaceae blue pig ear, and sweet in the mouth is cool in nature, clearing away heat-damp and promoting diuresis; Stomach function regulating preventing or arresting vomiting, blood stasis dispelling.Main jaundice; Stranguria with blood; Vomiting; Diarrhoea; Cough due to pathogenic wind-heat; Traumatic injury; Serpentis hinders; Furunculosis.
Herba Dregeae volubilis is Herb and the rhizome of asclepiadaceae plant Herba Dregeae volubilis, pungent, bitter, cool, attaches to the lung and stomach meridians, dispels the wind; Dehumidifying; Pain relieving; Clearing heat to ease the stomach.Main flu; Rheumatic arthritis; Lumbago; Vomiting during pregnancy; The esophageal carcinoma; Gastric cancer.
Cannon Fructus Tsaoko is the fruit of Malvaceae plant arrowleaf abelmoschus, sweet, light, flat, easing the affected liver the kidney invigorating; And stomach and alleviating pain.Main nephrasthenia deafness; Stomachache; Infantile malnutrition; Juvenile canities.
Radix Malloti Apelitae is the root of Radix Euphorbiae Pekinensis kind of plant Folium Malloti Apeltae, and mildly bitter flavor is puckery, flat, returns spleen, kidney, urinary bladder channel, heat clearing away; Damp eliminating; Astringent therapy; Repercussive.Main hepatitis intestinal is scorching; Stranguria with turbid discharge; Leukorrhagia; Proctoptosis; Uterine prolapse; Hepatosplenomegaly; Osteopatia sprain.
Radix Cephalanthi Occidentalis is root or the root bark of Maguireothamnus speciosus buttonbush, bitter, cool, returns lung, large intestine channel, clearing away heat-damp and promoting diuresis; Dissipating blood stasis for subsidence of swelling.Main cold, fever; Cough; Laryngopharynx swelling and pain; Hepatitis; Urinary tract infection; Pelvic inflammatory disease; Orchitis; Rheumatic arthritis; Carbuncle; Traumatic injury.
Shi Rong is the herb of Gesneriaceae awns hair lettuce tongue, pungent, light, cool, removing heat-phlegm, inducing diuresis to remove edema, eliminating stasis and resolving masses.For bronchitis, asthma, pulmonary tuberculosis, oedema due to nephritis, gastric cancer, esophageal carcinoma, hepatocarcinoma, breast carcinoma, pulmonary carcinoma; Traumatic injury is controlled in external, burn and scald, carbuncle furuncle.
Herba Viviae Sativae is herb or the seed of leguminous plant Herba Viviae Sativae, and sweet in the mouth is pungent, cold in nature, GUIXIN, liver, spleen channel, clearing away heat-damp and promoting diuresis, and blood and dissolving stasis.To harness the Yellow River subcutaneous ulcer, edema, malaria, epistaxis, cardiopalmus, nocturnal emission, menoxenia." vegetation is side just ": " invigorate blood circulation, removing blood stasis, hemostasis, granulation promoting.Control five jaundice to swell, sharp dirty heat.Preventing the attack (or recurrence) of malaria, flat stomach, improve visual and auditory acuity.″
Herba Thymi is the thymic herb of labiate, acrid in the mouth, and property is put down, dispelling wind stopping cough; Spleen invigorating circulation of qi promoting; Dampness removing is treating stranguria.Main headache due to common cold; Cough; Pertussis; Epigastric pain; Dyspepsia; Vomiting and diarrhoea; Toothache; Difficulty and pain in micturition; Eczema pruritus; Sore, carbuncle and painful swelling." Shaanxi Chinese herbal medicine ": warming spleen and stomach for dispelling cold, strengthening the spleen to promote digestion, analgesia of dispeling the wind.Control cold syndrome of the stomach pain, little distention and fullness in the abdomen, dyspepsia, general aching, toothache.
Radix vignae sinensis is the root of leguminous plant Semen vignae sinensis, sweet, flat, returns spleen, stomach warp, invigorating the spleen and benefiting QI; Removing food stagnancy; Removing toxic substances.Main weakness of the spleen and stomach; Food stagnation; Leucorrhea; Stranguria with turbid discharge; Hemorrhoidal bleeding; Furuncle.
Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. is the root of Passifloraceae plant Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep., and sweet, micro-hardship is cool, strengthening by means of tonics, wind-damp dispelling, the meridian dredging.For strengthening the spleen and stomach, invigorating the liver and kidney.
Crepis crocea Babc.(C.turczaninowii C.A.Mey.) is the root of feverfew Crepis phoenix Dunn, and bitter in the mouth is sweet, warm in nature, liver and kidney tonifying; Invigorating spleen to remove dampness.Master has a dizzy spell; Soreness of the waist and knees; Edema; Leukorrhagia infantile malnutrition; Hypogalactia.
Radix Polygoni Hydropiperis is the root of polygonaceae plant Herba Polygoni hydropiperis, pungent, warm in nature, promoting blood flow to regulate menstruation; Invigorating spleen to remove dampness; During removing toxic substances disappears.Main menoxenia; Infantile malnutrition; Dysentery; Intestinal is scorching; Malaria; Treating swelling and pain by traumatic injury; Snake bite and insect sting.
Herba Bulbophylli inconspicui is the herb of orchid Herba Bulbophylli inconspicui, sweet, pungent, cool, attaches to the lung and stomach meridians, heat clearing away YIN nourishing; To promote the production of body fluid nourishing the stomach, nourishing the lung to arrest cough.Main cough due to lung-heat; Pulmonary tuberculosis is spat blood; Have sore throat; Calentura excessive thirst; Rheumatic arthralgia; Menoxenia; Traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook ": " moistening the lung and resolving phlegm, tonifying-Yin and nourishing-stomach.Control pulmonary tuberculosis cough, spitting of blood, cough due to chronic tracheitis, pneumonia convalescent period, chronic pharyngalgia, chronic gastritis, achlorhydria, inappetence, seminal emission.″
The present invention has following beneficial effect: Chinese medicine composition of the present invention has effect of dispersing the stagnated liver-QI for regulating the stomach, clearing away heat-damp and promoting diuresis, stasis-dispelling and pain-killing, spleen invigorating warming middle-JIAO, tonifying-Yin and nourishing-stomach, effectively treats peptic ulcer, determined curative effect, not easily recurs, have no side effect.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Treat a Chinese medicine composition for peptic ulcer, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 3 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 6 parts, Ramulus et folium pyri betulaefoliae 7 parts, blue pig ear 4 parts, Herba Dregeae volubilis 5 parts, cannon Fructus Tsaoko 3 parts, Radix Malloti Apelitae 15 parts, Radix Cephalanthi Occidentalis 8 parts, stone banyan 3 parts, Herba Viviae Sativae 5 parts, Herba Thymi 2 parts, Radix vignae sinensis 12 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 5 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 15 parts, Radix Polygoni Hydropiperis 3 parts, Herba Bulbophylli inconspicui 15 parts.
Embodiment 2
Treat a Chinese medicine composition for peptic ulcer, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 5 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 8 parts, Ramulus et folium pyri betulaefoliae 5 parts, blue pig ear 5 parts, Herba Dregeae volubilis 4 parts, cannon Fructus Tsaoko 5 parts, Radix Malloti Apelitae 10 parts, Radix Cephalanthi Occidentalis 10 parts, stone banyan 5 parts, Herba Viviae Sativae 7 parts, Herba Thymi 5 parts, Radix vignae sinensis 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 8 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Radix Polygoni Hydropiperis 5 parts, Herba Bulbophylli inconspicui 10 parts.
Embodiment 3
Treat a Chinese medicine composition for peptic ulcer, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 4 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 5 parts, Ramulus et folium pyri betulaefoliae 6 parts, blue pig ear 4 parts, Herba Dregeae volubilis 2 parts, cannon Fructus Tsaoko 7 parts, Radix Malloti Apelitae 13 parts, Radix Cephalanthi Occidentalis 5 parts, stone banyan 7 parts, Herba Viviae Sativae 3 parts, Herba Thymi 4 parts, Radix vignae sinensis 5 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 10 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 8 parts, Radix Polygoni Hydropiperis 6 parts, Herba Bulbophylli inconspicui 5 parts.
Embodiment 4
Treat a Chinese medicine composition for peptic ulcer, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 6 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 parts, Ramulus et folium pyri betulaefoliae 10 parts, blue pig ear 3 parts, Herba Dregeae volubilis 3 parts, cannon Fructus Tsaoko 6 parts, Radix Malloti Apelitae 8 parts, Radix Cephalanthi Occidentalis 12 parts, stone banyan 4 parts, Herba Viviae Sativae 6 parts, Herba Thymi 3 parts, Radix vignae sinensis 8 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 12 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 13 parts, Radix Polygoni Hydropiperis 8 parts, Herba Bulbophylli inconspicui 8 parts.
Clinical data
With Chinese medicine composition of the present invention, the patient that 112 examples are diagnosed as peptic ulcer is treated, wherein male 67 example, women 45 example, age 21-67 year, 41 years old mean age.
Therapeutic Method: Chinese medicine composition of the present invention is decocted in water for oral dose, every day potion, one day twice, sooner or later sub-service 15 days was a course for the treatment of;
Curative effect judging standard:
Cure: ulcer surface heals, and symptom disappears completely, within more than 1 year, does not recur;
Effective: ulcer surface reduces, symptom alleviates;
Invalid: ulcer surface and symptom, without improvement, even increase the weight of.
Therapeutic outcome: 112 routine patients cure 91 examples, effective 15 examples, invalid 6 examples, cure rate 81.25%, total effective rate 94.6%, in therapeutic process there is not bad side reaction in patient, and hematuria is conventional, hepatic and renal function is all normal.

Claims (2)

1. treat a Chinese medicine composition for peptic ulcer, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Flos Citri Sarcodactylis 3-6 part, Citrus chachiensis Hort. (C. Suavissima Tanaka) 5-10 part, Ramulus et folium pyri betulaefoliae 5-10 part, blue pig ear 3-5 part, Herba Dregeae volubilis 2-5 part, cannon Fructus Tsaoko 3-7 part, Radix Malloti Apelitae 8-15 part, Radix Cephalanthi Occidentalis 5-12 part, Shi Rong 3-7 part, Herba Viviae Sativae 3-7 part, Herba Thymi 2-5 part, Radix vignae sinensis 5-15 part, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 5-12 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 8-15 part, Radix Polygoni Hydropiperis 3-8 part, Herba Bulbophylli inconspicui 5-15 part.
2. a kind of Chinese medicine composition for the treatment of peptic ulcer as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight parts: Flos Citri Sarcodactylis 5 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 8 parts, Ramulus et folium pyri betulaefoliae 5 parts, blue pig ear 5 parts, Herba Dregeae volubilis 4 parts, cannon Fructus Tsaoko 5 parts, Radix Malloti Apelitae 10 parts, Radix Cephalanthi Occidentalis 10 parts, Shi Rong 5 parts, Herba Viviae Sativae 7 parts, Herba Thymi 5 parts, Radix vignae sinensis 10 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 8 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 10 parts, Radix Polygoni Hydropiperis 5 parts, Herba Bulbophylli inconspicui 10 parts.
CN201511017420.1A 2015-12-31 2015-12-31 Traditional Chinese medicinal composition for treating peptic ulcer Pending CN105560858A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020235987A1 (en) * 2019-05-17 2020-11-26 Flora Solutions Sdn. Bhd. Use of adenia cordifolia extract for wound healing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周德生等: "《名医推荐家庭必备名方 珍藏本》", 30 September 2015, 湖南科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020235987A1 (en) * 2019-05-17 2020-11-26 Flora Solutions Sdn. Bhd. Use of adenia cordifolia extract for wound healing

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