CN1739638A - Medicine for treating dermatosis and its prepn - Google Patents

Medicine for treating dermatosis and its prepn Download PDF

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CN1739638A
CN1739638A CN 200510003192 CN200510003192A CN1739638A CN 1739638 A CN1739638 A CN 1739638A CN 200510003192 CN200510003192 CN 200510003192 CN 200510003192 A CN200510003192 A CN 200510003192A CN 1739638 A CN1739638 A CN 1739638A
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parts
rhubarb
berberine
flea
drug
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CN 200510003192
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CN100360160C (en )
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赵运荣
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赵运荣
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The medicine for treating dermatosis is prepared with five kinds of Chinese medicinal materials, including paris rhizome, Chinese goldthread, skullcap root, rhubarb and gromwell, and the recipe may have other four kinds of Chinese medicinal materials in certain weight proportion. It may be medicine powder, decoction, ointment or paste. The medicine has the functions of clearing away heat and toxic material, promoting blood circulation to disperse blood clots, eliminating swelling and pain, etc. and may be used in treating acne, bedsore, boil, eczema, dermatitis, burns, scalds and other dermatosis. It has the advantages of high healing effect, fast acting, no irritation to skin, etc.

Description

一种治疗皮肤病的药物及其制备方法 A pharmaceutical preparation and method of treatment of dermatoses

[技术领域]本发明涉及一种治疗皮肤病的药物及其制备方法,属于中药技术领域。 [Technical Field] The present invention relates to a pharmaceutical preparation and method of treating skin diseases, belonging to the technical field of traditional Chinese medicine.

[背景技术]皮肤病为常见疾病之一,尤其是痤疮、湿疹、褥疮、皮炎、带状疱疹、烧烫伤在临床较为常见,这些病种,临床上采用中、西医治疗均取得较好的疗效。 [Background] skin disease is a common disease, especially acne, eczema, bed sores, dermatitis, shingles, burns in clinical more common, these diseases, the clinical use of Western medicine treatment have achieved better results . 长期以来,医务工作者力求探索一种能够治疗细菌性和病毒性皮肤病的药物.在专利文献中所公开的治疗多种皮肤病的药物,如胡祥仁在CN1621074A申请件中描述治疗皮肤病的药物,能够治疗皮炎、褥疮、烧烫伤,仅限于治疗细菌性皮肤病,未涉及到病毒性皮肤病的治疗,如带状疱疹、单纯性疱疹。 For a long time, seek medical workers to explore a drug capable of treating bacterial and viral skin diseases. Pharmaceutical in the treatment of various skin diseases as disclosed in the patent literature, such as in the Hu Xiangren application CN1621074A member described in dermatology drugs to treat dermatitis, bedsores, burns, is limited to the treatment of bacterial skin disease, not related to the treatment of viral skin diseases, such as herpes zoster, herpes simplex. 在临床上以及患者对能够有效治疗细菌性和病毒性皮肤病的药物仍存在需求。 In clinical practice and the patient's medication can be effective in the treatment of bacterial and viral skin disease still exists demand. 至今为止,还没有发现有关本发明药物组合物相同的报道。 So far, we have not found reports of the same pharmaceutical composition of the present invention.

[发明内容]本发明目的在于提供一种能够有效治疗细菌性和病毒性皮肤病的药物。 [Disclosure of Invention] The present invention aims to provide an effective treatment of bacterial and viral skin disease drug.

本发明的另外一个目的是提供了该药物的制备方法。 Another object of the present invention is to provide a method for preparing the medicament.

本发明的药物选择蚤休、黄连、黄芩、大黄、紫草进行组合,其中选用蚤休是因为蚤休性味苦寒,具有清热解毒,消肿止痛,凉血祛风,既能解痈毒,又能疗疮疡,对痈疽疮疡血热致病者宜用。 Drug selection flea present invention, berberine, baicalin, rhubarb, comfrey combination, which is selected because of flea flea taste bitter cold, with detoxification, swelling and pain, chills and cooling, both drug solution carbuncle, but sore treatment of ulcer sore pathogenic blood by heat is appropriate. 选用黄连、黄芩、大黄、紫草,是因为黄连性味苦寒,清热燥湿,泻火解毒,疗疮毒,现代药理研究证实,黄连具有抗菌,抗真菌,抗病毒作用,对7种革兰氏阴性菌和5种革兰氏阳性菌有较强的抑制作用。 Selection berberine, baicalin, rhubarb, comfrey, because Coptis taste bitter cold, dampness heat, purging fire detoxification, sore treatment, Modern pharmacological studies confirmed that berberine has antibacterial, antifungal, antiviral, seven kinds of Gram Gram-negative bacteria and five Gram-positive bacteria have a strong inhibitory effect. 黄芩,性味苦寒,清热燥湿,泻火解毒,疗痈肿疮毒。 Skullcap, taste bitter cold, dampness heat, purging fire detoxification, carbuncles sore treatment. 现代药理研究证实,黄芩具有抗菌、抗真菌、抗病毒、抗炎、抗变态反应。 Modern pharmacological studies confirmed skullcap has anti-bacterial, anti-fungal, anti-viral, anti-inflammatory, anti-allergic. 大黄,性味苦寒,清热泻火,活血解毒,逐瘀通经,疗痈肿疔疮,具有清热泻火,活血祛瘀双重作用,大黄为泻下药(泄热),配伍清热泻火之品(黄连、黄芩)清下并用,以加强清热之效。 Rhubarb, taste bitter cold, heat purging fire, blood detoxification, stasis pass through, treatment carbuncle swollen boils, has a dual role of heat purging fire, stasis, rhubarb is a prescription diarrhea (Xiere), compatibility of the product heat purging fire (berberine, baicalin) and dried under clear to enhance the heat effect. 紫草,性味苦寒,凉血活血,清热解毒,透疹,用于血热毒盛,斑疹不透,痈肿疮疡。 Lithospermum, taste bitter cold, cooling blood, detoxification, Touzhen for blood toxic heat Sheng, rash impervious, carbuncles sore. 此四味药清热解毒,泻火凉血,活血散瘀,共助蚤休之功效。 This four herbs detoxification, purging fire, cooling blood, blood stasis, the co-promoter fleas off effect.

为了达到更好的疗效,本发明的药物还与虎杖、栀子、黄柏、红藤组合,选择虎杖,性味微苦、微寒,祛风利湿,散瘀定痛,用于痈肿疮毒,烧烫伤。 To achieve better results, the present invention is also a pharmaceutical Polygonum cuspidatum, gardenia, Cork, SFAS combination with selected knotweed, bitter taste, slightly cold, expelling wind and dampness, stasis and pain, sore for carbuncles poison, burn. 现代药理研究证实,虎杖有抗菌,抗病毒和解热镇痛作用。 Modern pharmacological studies confirmed that Polygonum cuspidatum has anti-bacterial, anti-viral and anti-inflammatory effect. 栀子,性味苦寒,有清热解毒,泻火凉血之功,用于火毒疮疡,肿痛伤痛。 Gardenia, taste bitter cold, detoxification, purging fire power of the cooling for the fire canker sores, swelling and pain. 黄柏,性味苦寒,清热燥湿,泻火除蒸,解毒疗疮。 Cork, taste bitter cold, heat and dampness, purging fire addition to steam, detoxification treatment and sore. 用于疮疡肿毒,湿疹瘙痒。 For sores, eczema itching. 现代药理研究证实黄柏有抗菌抗溃疡作用。 Modern pharmacological studies confirmed that Cork has antibacterial anti-ulcer effect. 红藤,性味苦平,有清热解毒,活血散瘀止痛之功,用于热毒疮疡。 SFAS, of bitter flat, detoxification, blood stasis analgesic power for heat canker sores. 以上四味药,共助君臣之品清热解毒,泻火凉血,活血散瘀之功。 These four herbs, the co-promoter monarch detoxification products, cooling and purging fire, blood stasis of power.

本发明药物组分的用量是经过发明人大量的临床摸索总结出的,其中至少包含蚤休、黄连、黄芩、大黄、紫草5味药,原料药有效用量在下述重量份范围具有较好疗效:蚤休10-30份、黄连8-16份、黄芩8-16份、大黄8-16份、紫草5-10份。 The amount of the drug component is the result of the inventors of the present invention, a number of clinical exploration summed, comprising at least flea, berberine, baicalin, rhubarb, herb comfrey 5, the effective amount of the drug has a good effect in the following parts by weight : flea 10-30 parts, 8-16 parts of berberine, skullcap 8-16 parts, 8-16 parts rhubarb, comfrey 5-10 parts.

优选为:蚤休15份、黄连10份、黄芩10份、大黄10份、紫草5份。 Preferably: flea 15 parts, 10 parts of berberine, skullcap 10 parts, 10 parts of rhubarb, comfrey 5 parts.

为提高疗效,还可以添加虎杖、栀子、黄柏、红藤4味药。 In order to improve the efficacy, you can add Polygonum cuspidatum, gardenia, Cork, SFAS 4 herbs.

本发明药物原料药用量还可以是:蚤休10-30份、黄连8-16份、黄芩8-16份、大黄8-16份、紫草5-10份、虎杖10-30份、栀子8-16份、黄柏8-16份、红藤8-16份。 A pharmaceutically acceptable amount of drug raw material of the present invention may also be: 10-30 parts by flea, 8-16 parts of berberine, skullcap 8-16 parts, 8-16 parts rhubarb, comfrey 5-10 parts, 10-30 parts of Polygonum cuspidatum, gardenia child 8-16 copies, Cork 8-16 copies, SFAS 8-16 copies.

优选为:蚤休15份、黄连10份、黄芩10份、大黄10份、紫草5份、虎杖15份、栀子10份、黄柏10份、红藤10份。 Preferably: flea 15 parts, 10 parts of berberine, skullcap 10 parts, 10 parts of rhubarb, comfrey 5 parts, 15 parts of Polygonum cuspidatum, gardenia 10 parts, 10 parts of cork, 10 parts SFAS.

本发明药物采用中药制剂的制备方法制成任何常规外用制剂,例如可以将这些原料药研磨成粉未混合均匀制成膏剂、水剂、油剂、糊剂、粉剂使用,但是为了使这些原料药更好地发挥其药效,优选本发明活性组份的制备方法如下:a)按照重量配比称取各原料药蚤休,黄连、黄芩、大黄、紫草备用;b)将上述的蚤休、黄连、黄芩、大黄、紫草用水煎煮2次,每次1.5小时,合并两次煎煮液,过滤后浓缩成稠膏,在45-50℃温度下干燥,制得干浸膏I;c)将煎煮后的药渣用乙醇回流提取2次,合并两次提取液,过滤后回收乙醇并浓缩成稠膏,在45-50℃温度下燥,制得干浸膏II;d)合并干浸膏I和II,将其粉碎成粉,就制成了本发明药物的活性组份;如果还与虎杖、栀子、黄柏、红藤组合,其制备方法为:a)按照配方的重量配比称取各原料药蚤休、黄连、黄芩、大黄、紫 Pharmaceutical preparation of the present invention herbal preparations made from any conventional external preparations, for example, the drug can be milled to a powder made of mixed paste, liquid, oil, paste, powder used, but in order for these drug better play its efficacy, the active ingredient of the present invention is preferably prepared as follows: a) in a weight ratio of each raw material was weighed drug flea, berberine, baicalin, rhubarb, Lithospermum standby; b) the above-flea , berberine, baicalin, rhubarb, comfrey boiling water 2 times, each 1.5 hours, the two combined decoction, filtered and concentrated to a thick paste, dried to obtain dry extract I at a temperature of 45-50 deg.] C; c) the dregs of decoction extracted twice with ethanol at reflux, the two extracts were combined, filtered and concentrated to recovering ethanol thick paste, drying at a temperature of 45-50 deg.] C, to obtain a dry extract II; d) combined dry extract I and II, which is pulverized into powder, the active ingredient will be made of the present invention is a pharmaceutical; if it knotweed, gardenia, Cork, SFAS combination with methods for their preparation are: a) in accordance with the formula the weight ratio of each raw material was weighed drug flea, berberine, baicalin, rhubarb, purple 草、虎杖、栀子、黄柏、红藤备用;b)将上述的蚤休、黄连、黄芩、大黄、紫草、虎杖、栀子、黄柏、红藤用水煎煮2次,每次1.5小时,合并两次煎煮液,制得干浸膏III;c)将煎煮后的药渣用乙醇回流提取2次,合并两次提取液,过滤后回收乙醇并浓缩成稠膏,在45-50℃温度下干燥,制得干浸膏IV;d)合并干浸膏III和IV,将其粉碎成粉,就制成本发明药物的活性组份。 Grass, giant knotweed, gardenia, Cork, SFAS standby; b) the above-mentioned flea, berberine, baicalin, rhubarb, comfrey, Polygonum cuspidatum, gardenia, Cork, SFAS boiling water 2 times, each 1.5 hours, the combined two decoction prepared dry extract III; c) the dregs of decoction extracted twice with ethanol at reflux, the two extracts were combined, filtered and concentrated to recover a thick paste of ethanol, 45-50 at a temperature ℃ dried to obtain dry extract IV; d) combined dry extract III and IV, which is pulverized into powder, manufactured on the cost of the invention the pharmaceutical active parts.

本发明药物的活性组份可以加放入制备不同外用剂型时所需的各种辅料,如凡士林、羊毛脂、麻油、菜油、液体石蜡、蒸溜水、甘油等以常规的中药制剂制备成任何一种常用的外用剂型,如粉剂、水剂、膏剂、糊剂、乳剂。 Parts of the active agents of the invention can be added into various different materials required in the preparation of topical dosage forms, such as petrolatum, lanolin, sesame oil, vegetable oil, liquid paraffin, distilled water, glycerin and the like prepared in any conventional Chinese medicine species commonly used in topical form, such as powders, liquid, ointment, pastes, creams.

本发明的药物具有清热解毒,泻火凉血、活血散瘀、消肿止痛,祛腐生肌,消炎抗菌、抗病毒之功能,用于治疗痤疮、褥疮、疖子、湿疹、皮炎、带状疱疹、单纯性庖疹、以及烧烫伤。 Medicament of the present invention have a detoxification, purging fire, cooling blood, blood stasis, swelling and pain, remove rot myogenic, antibacterial anti-inflammatory, anti-virus function, for the treatment of acne, bedsores, boil, eczema, dermatitis, herpes zoster, herpes simplex, and burns.

[具体实施方式]下面通过临床试验统计及典型病例来进一步说明本发明药物的有益效果。 [DETAILED DESCRIPTION] below to further illustrate the present invention, the beneficial effects of the drug through clinical trials and statistical typical cases.

本发明药物发明人自制成“金圣疮疡愈膏”,自1998年以来,用于治疗痤疮、褥疮、湿疹、皮炎、疖子、带状疱疹、单纯性疱疹,以及烧烫伤病272例,治疗情况统计如下: The present invention since the drug is made, "Kim Sung more sore cream", since 1998, used to treat acne, bedsores, eczema, dermatitis, boils, herpes zoster, herpes simplex, and burns 272 cases of the disease, treatment statistics are as follows:

各种病例统计表 Various cases statistics

典型病例:刘朝显,男,80岁,住贵阳市洛湾大堡村。 A typical case: Chao-significant, M, 80 years old, living in Guiyang City Luo Bay fort. 患脑溢血后卧床不起,半年后臀部出现褥疮,疮面1.5×1.5cm 3处,使用该药10日后,痊愈。 Bedridden patients after stroke, six months after the buttocks bedsores, 1.5 × 1.5cm 3 at the wound, the use of the drug for 10 days, recovered.

鞠建英,女,35岁,住贵阳市内,联系电话:13985550153,面部,额头皮肤凹凸不平,红痒,毛孔粗糙,诊断为痤疮,使用该药20日后,皮肤平整,不红、不痒,皮肤毛孔明显缩小,7年未复发。 Ju Jianying, female, 35 years old, live in the city of Guiyang, Tel: 13985550153, face, forehead uneven skin, red itchy, rough pores, acne diagnosis, use of the drug 20 days, the skin is smooth, not red, no itching, skin pores significantly reduced, 7 years without recurrence.

孙梦蝶,女,46岁,贵州橡胶大众有限公司质检科职工,2000年患带状疱疹,遍布前胸和背部,疼痛难忍,准备住院治疗。 Sun Meng, female, 46 years old, Guizhou public Rubber Co., Ltd. Quality Division staff in 2000 suffering from shingles, all over chest and back pain, ready to hospitalization. 使用该药后,20日痊愈未住院。 After using the drug 20 days recovery is not hospitalized.

周家萍,女,43岁,贵阳立云大酒店职工,2002年正月初二被高压锅溢出卤汁将整个面部烫伤,面部红肿,水泡满布,双目不能睁开,口不能张开,诊断为II级烫伤,使用金圣疮疡愈膏后1小时,双目能睁开,能说话,10日后,整个面部恢复完好如初。 Zhoujia Ping, female, 43 years old, Guiyang Li-yun hotel staff, two days of the first month of 2002 is a pressure cooker overflow marinade will burn the entire face, facial swelling, blisters covered, can not open my eyes, I can not open, diagnosis II grade burns, gold holy hour after the sore healing cream, can open your eyes, speak, 10 days later, the entire face recovery intact.

丰令涵,女,1岁半,住贵阳市百花山路10号二单元,1999年冬季,不慎跌坐于石英炉上,臀部及外阴烧伤,诊断为II级烧伤,使用该药后,疼痛立即减轻,10日而愈,无疤痕。 Han Feng made, female, half years old, live in Guiyang City flowers Hill Road, Unit No. 10, Winter 1999, accidentally fell on a quartz furnace, buttocks and genital burns, the diagnosis of grade II burns after using the drug, pain immediate relief, on the 10th and more, without scars.

使用本发明药物期间,忌食辛、辣、鱼、海鲜,豆制品;阴症者禁用。 During use of drugs of the present invention, eat Sim, spicy, fish, seafood, soy; female patients who disabled.

[实施例]以下通过实施例来进一步阐述本发明的制备方法;实施例1:本发明药物的水剂制备a)称取蚤休15g,黄连、黄芩、大黄、虎杖、栀子、黄柏、红藤各10g,紫草5g,加水煎煮2次,每次1.5小时,合并两次煎液,过滤后浓缩成稠膏,在45-50℃下干燥,制得干浸膏I;b)将煎煮后药渣用乙醇进行回流提取2次,每次2小时,合并两次提取液,过滤,回收乙醇并浓缩成稠膏,在45-50℃下干燥,制得干浸膏II;c)合并干浸膏I和II,将其粉碎成粉,就制成了本发明药物的活性组份;d)将上述提取的药物活性组份按1∶200重量比加入蒸溜水,再加入10%甘油,制成水剂。 [Example] The following further illustrate the preparation process of the present invention, examples; Example 1: Preparation of a pharmaceutical agent of the present invention a) Weigh flea 15g, berberine, baicalin, rhubarb, knotweed, gardenia, Cork, red each vine 10g, Lithospermum 5g, boiling water 2 times, each 1.5 hours, the two combined decoction, filtered and concentrated to a thick paste, dried at 45-50 deg.] C, to obtain a dry extract I; b) the dregs after boiling with ethanol was extracted twice, each time for 2 hours and the two extracts were combined, filtered, and concentrated to recover a thick paste of ethanol, and dried at 45-50 deg.] C, to obtain a dry extract II; c ) combined dry extract I and II, which was pulverized into powder, made on the parts of the present invention is a pharmaceutical active ingredient; D) the extracted parts of the pharmaceutical active by weight by addition of distilled water 1:200 slide, then add 10 % glycerol, made liquid.

实施例2:本发明药物的膏剂制备a)称取蚤休15g,黄连、黄芩、大黄、虎杖、栀子、黄柏、红藤各10g,紫草5g,加水煎煮2次,每次1.5小时,过滤后浓缩成稠膏,在45-50℃下干燥,制得干浸膏I;b)将煎煮后药渣用乙醇进行回流提取2次,每次2小时,合并两次提取液,过滤,回收乙醇并浓缩成稠膏,在45-50℃下干燥,制得干浸膏II;c)合并干浸膏I和II,将其粉碎成粉,就制成了本发明药物的活性组份;d)将上述提取的药物活性组份加入凡士林200g、羊毛脂20g,混合均匀后,制成膏剂,即为发明人自制的“金圣疮疡愈膏”。 Example 2: Preparation of medicament paste of the present invention a) Weigh flea 15g, berberine, baicalin, rhubarb, knotweed, gardenia, Cork, each SFAS 10g, Lithospermum 5g, boiling water 2 times, each 1.5 hours , filtered and concentrated to a thick paste, dried at 45-50 deg.] C, to obtain a dry extract I; b) dregs after boiling extracted twice by reflux with ethanol, 2 hours each time, the two extracts were combined, filtering, recovering ethanol and concentrated to a thick paste, dried at 45-50 deg.] C, to obtain a dry extract II; c) combined dry extract I and II, which is pulverized into powder, the active agent can be made according to the present invention component; D) the pharmaceutically active component is added to the extracted petrolatum 200g, lanolin 20g, uniformly mixed to prepare a paste, that is, the inventors made "more Jinsheng sore cream."

实施例3:本发明药物的糊剂制备a)称取蚤休15g,黄连、黄芩、大黄、虎杖、栀子、黄柏、红藤各10g,紫草5g,加水煎煮2次,每次1.5小时,合并两次煎液,过滤后浓缩成稠膏,在45-50℃下干燥,制得干浸膏I; Example 3: Preparation of medicament paste of the present invention a) Weigh flea 15g, berberine, baicalin, rhubarb, knotweed, gardenia, Cork, each SFAS 10g, Lithospermum 5g, boiling water 2 times, each 1.5 hour, combined two decoction, filtered and concentrated to a thick paste, dried at 45-50 deg.] C, to obtain a dry extract I;

b)将煎煮后药渣用乙醇进行回流提取2次,每次2小时,合并两次提取液,过滤,回收乙醇并浓缩成稠膏,在45-50℃下干燥,制得干浸膏II;c)合并干浸膏I和II,将其粉碎成粉,就制成了本发明药物的活性组份;d)将上述提取的药物活性组份加入凡士林200g、甘油20g、滑石粉50g,混合均匀后制成糊剂。 b) After boiling under reflux for dregs for extraction with ethanol 2 times, 2 hours each time, the two extracts were combined, filtered, and concentrated to recover a thick paste of ethanol, and dried at 45-50 deg.] C, to obtain a dry extract II; c) combined dry extract I and II, which was pulverized into powder, made on the parts of the present invention is a pharmaceutical active ingredient; D) the pharmaceutically active component is added to the extracted petrolatum 200g, glycerol 20g, 50g talc mixed uniformly made of a paste.

Claims (7)

  1. 1 一种治疗皮肤病的药物,其特征在于该药物至少包含蚤休、黄连、黄芩、大黄、紫草5味药,各原料药有效用量在下述重量份范围:蚤休10-30份、黄连8-16份、黄芩8-16份、大黄8-16份、紫草5-10份。 1. A pharmaceutical treatment of skin diseases, characterized in that the medicament comprises at least flea, berberine, baicalin, rhubarb, 5 herb comfrey, effective amounts of each drug in the following parts by weight: 10-30 parts by flea, berberine 8-16 parts, 8-16 parts skullcap, rhubarb parts 8-16, 5-10 parts comfrey.
  2. 2 根据权利要求1所述的药物,其特征是上述原料药的重量份为:蚤休15份、黄连10份、黄芩10份、大黄10份、紫草5份。 2 medicament according to claim 1, characterized in that the parts by weight of the drug is: flea 15 parts, 10 parts of berberine, skullcap 10 parts, 10 parts of rhubarb, comfrey 5 parts.
  3. 3 根据权利要求1或2药物的制备方法,其特征在于该方法包括下列步骤:a)按照重量配比称取各原料药蚤休,黄连、黄芩、大黄、紫草备用;b)将上述的蚤休、黄连、黄芩、大黄、紫草用水煎煮2次,每次1.5小时,合并两次煎煮液,过滤后浓缩成稠膏,在45-50℃温度下干燥,制得干浸膏I;c)将煎煮后的药渣用乙醇回流提取2次,合并两次提取液,过滤后回收乙醇并浓缩成稠膏,在45-50℃温度下燥,制得干浸膏II;d)合并干浸膏I和II,将其粉碎成粉,就制成了本发明药物的活性组份。 3 prepared according to Method 1 or claim 2 drugs, which is characterized in that the method comprises the following steps: a) in a weight ratio of each raw material was weighed drug flea, berberine, baicalin, rhubarb, Lithospermum standby; b) the above-mentioned flea, berberine, baicalin, rhubarb, comfrey boiling water 2 times, each 1.5 hours, the two combined decoction, filtered and concentrated to a thick paste, drying at a temperature of 45-50 deg.] C, to obtain a dry extract I; c) the dregs of decoction extracted twice with ethanol at reflux, the two extracts were combined, filtered and concentrated to recovering ethanol thick paste, drying at a temperature of 45-50 deg.] C, to obtain a dry extract II; d) combining dry extract I and II, which was pulverized into powder, made on the parts of the present invention is a pharmaceutical active ingredient.
  4. 4 根据权利要求1所述的药物,其特征是上述原料药中还可以添加虎杖、栀子、黄柏、红藤4味药,各原料药重量份为:蚤休10-30份、黄连8-16份、黄芩8-16份、大黄8-16份、紫草5-10份、虎杖10-30份、栀子8-16份、黄柏8-16份、红藤8-16份。 4 Drug according to claim 1, wherein said drug may be added knotweed, gardenia, Cork, herb SFAS 4, parts by weight of each drug: 10-30 parts by flea, berberine 8- 16 parts, 8-16 parts skullcap, rhubarb 8-16 parts, Radix 5-10 parts, 10-30 parts of Polygonum cuspidatum, gardenia parts 8-16, 8-16 parts of cork, SFAS 8-16 parts.
  5. 5 根据权利要求1所述的药物,其特征是各原料药重量份为:蚤休15份、黄连10份、黄芩10份、大黄10份、紫草5份、虎杖15份、栀子10份、黄柏10份、红藤10份。 5 medicament according to claim 1, characterized in that each of the parts by weight of the drug: flea 15 parts, 10 parts of berberine, skullcap 10 parts, 10 parts of rhubarb, comfrey 5 parts, 15 parts of Polygonum cuspidatum, 10 parts of gardenia , Cork 10 parts, 10 parts SFAS.
  6. 6 根据权利要求4或5药物的制备方法,其特征在于该方法包括下列步骤:a)按照配方的重量配比称取各原料药蚤休、黄连、黄芩、大黄、紫草、虎杖、栀子、黄柏、红藤备用;b)将上述的蚤休、黄连、黄芩、大黄、紫草、虎杖、栀子、黄柏、红藤用水煎煮2次,每次1.5小时,合并两次煎煮液,制得干浸膏III;c)将煎煮后的药渣用乙醇回流提取2次,合并两次提取液,过滤后回收乙醇并浓缩成稠膏,在45-50℃温度下干燥,制得干浸膏IV;d)合并干浸膏III和IV,将其粉碎成粉,就制成本发明药物的活性组份。 64 or a pharmaceutical preparation according to claim 5, characterized in that the method comprises the following steps: a) in a weight ratio of formulation of each drug was weighed flea, berberine, baicalin, rhubarb, comfrey, Polygonum cuspidatum, gardenia , Cork, SFAS standby; b) the above-mentioned flea, berberine, baicalin, rhubarb, comfrey, Polygonum cuspidatum, gardenia, Cork, SFAS boiling water 2 times, each 1.5 hours, the two combined decoction prepared dry extract III; c) the dregs of decoction extracted twice with ethanol at reflux, the two extracts were combined, filtered and concentrated to recover a thick paste of ethanol, and dried at a temperature of 45-50 deg.] C, prepared obtained dry extract IV; d) combined dry extract III and IV, which is pulverized into powder, manufactured on the cost of the invention the pharmaceutical active parts.
  7. 7 根据权利要求1所述的药物的制备方法,其特征是该药物可制成外用粉剂、水剂、膏剂、糊剂。 7 The method of preparing the medicament according to claim 1, characterized in that the pharmaceutical powder can be made into an external, liquid, ointment, paste.
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CN100386106C (en) 2006-06-23 2008-05-07 段阳泉 Medicine for treating acne and its preparation method
CN102028793A (en) * 2010-11-19 2011-04-27 黄文扬 Traditional Chinese medicinal composition for treating burns and scalding
CN101584773B (en) 2009-06-10 2011-05-11 张学贵 Chinese herbal medicament for treating skin diseases
CN101732462B (en) 2009-11-11 2012-01-11 宋爱民 Chinese medicinal preparation for treating herpes zoster
CN102579637A (en) * 2012-03-14 2012-07-18 广西强寿药业集团有限公司 Chinese patent drug--herpes virus tablet for treating herpes simplex virus as well as preparation method of same
CN102579651A (en) * 2012-03-19 2012-07-18 江景华 Traditional Chinese medicine preparation for treating traumata and bedsore
CN104800429A (en) * 2015-05-25 2015-07-29 石倩文 Ointment for external use for treating acne and preparation method of ointment
CN104940369A (en) * 2015-07-03 2015-09-30 赵德欣 External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100386106C (en) 2006-06-23 2008-05-07 段阳泉 Medicine for treating acne and its preparation method
CN101584773B (en) 2009-06-10 2011-05-11 张学贵 Chinese herbal medicament for treating skin diseases
CN101732462B (en) 2009-11-11 2012-01-11 宋爱民 Chinese medicinal preparation for treating herpes zoster
CN102028793A (en) * 2010-11-19 2011-04-27 黄文扬 Traditional Chinese medicinal composition for treating burns and scalding
CN102028793B (en) 2010-11-19 2012-01-04 黄文扬 Traditional Chinese medicinal composition for treating burns and scalding
CN102579637A (en) * 2012-03-14 2012-07-18 广西强寿药业集团有限公司 Chinese patent drug--herpes virus tablet for treating herpes simplex virus as well as preparation method of same
CN102579651A (en) * 2012-03-19 2012-07-18 江景华 Traditional Chinese medicine preparation for treating traumata and bedsore
CN102579651B (en) 2012-03-19 2013-11-20 江景华 Traditional Chinese medicine preparation for treating traumata and bedsore
CN104800429A (en) * 2015-05-25 2015-07-29 石倩文 Ointment for external use for treating acne and preparation method of ointment
CN104940369A (en) * 2015-07-03 2015-09-30 赵德欣 External use traditional Chinese medicine composition for treating herpes zoster and preparation method thereof

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