CN1223127A - Tongguanshugan ointment and preparation process thereof - Google Patents
Tongguanshugan ointment and preparation process thereof Download PDFInfo
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- CN1223127A CN1223127A CN98104834A CN98104834A CN1223127A CN 1223127 A CN1223127 A CN 1223127A CN 98104834 A CN98104834 A CN 98104834A CN 98104834 A CN98104834 A CN 98104834A CN 1223127 A CN1223127 A CN 1223127A
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Abstract
The present invention relates to a kind of adhesive plaster for curing hepatic diseases. It is made up by adopting the Chinese medicinal materials as raw materials, and respectively prepared into two kinds of adhesive plaster, type A and type B. These both plasters can be mounted on the hepatic region position one after another so as to attain the goal of curing hepatic diseases by means of infiltration of medicinal components into the hepatic region, and can obtain the good therapeutic effect.
Description
The present invention relates to a kind of medicine for the treatment of the hepatitis disease, is the medicine of feedstock production with Chinese medicine specifically, the invention still further relates to the preparation method of this medicine.
Hepatopathy is a kind of disease of serious harm humans health, and it not only has infectiousness, and should not cure, and therefore suffers from this sick people and not only self agonizes, and bring very big mental burden to the people around.
For treating this disease, now existing many medical personnels work hard for it, except that the medicine of having sold on the market, a kind of collocation method of Antiheptitic " Ganyanling " has been announced in patent application 91106266 and 91109404 respectively, and preparation of oral liquor for quick curing hepatitis, these two kinds of medicines are the patent medicine that raw material processes with the Chinese herbal medicine all, and they all have certain curative effect, but they are oral drugs.
The purpose of this invention is to provide and a kind ofly can directly act on the hepatic region, can remove the external used medicine of the strong treatment hepatopathy of hardship that patient takes medicine and penetration from.
Another object of the present invention provides the preparation method of this medicine.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to hepatopathy, achievement with reference to modern pharmacological research, from the Chinese medicine treasure-house, filter out and have strengthening the body resistance, removing heat from blood and promoting blood circulation, the yin nourishing of regulating the flow of vital energy, clearing away heat-damp and promoting diuresis, it is eliminating evil to detoxify, the natural drug of eliminating turbid pathogen with aromatics is formed, and distinctive processing technology in addition, and manufacturing forms.
The present invention is prepared from (consumption is a weight portion) by following medicine components:
Moschus 0.5-5 part Calculus Bovis 0.3-3 part
Resina Ferulae 20-90 part Sanguis Draxonis 20-90 part
Fructus Crotonis 15-80 part Semen Sinapis Albae 15-80 part
Semen Momordicae 35-120 part Squama Manis 20-120 part
Fructus Amomi 1.5-9 part Resina garciniae 50-180 part
Radix Bupleuri 20-80 part Herba Artemisiae Scopariae 20-80 part
Scolopendra 2-8 part Scorpio 2-8 part
Elderly woman hair 10-40 part
The oily 140-910 part milk of little mill 84-496 part
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Moschus 0.8-3 part Calculus Bovis 0.5-2 part
Resina Ferulae 20-60 part Sanguis Draxonis 20-60 part
Fructus Crotonis 20-50 part is from Semen Sinapis 20-50 part
Semen Momordicae 40-85 part Squama Manis 25-100 part
Fructus Amomi 1.5-7 part Resina garciniae 60-150 part
Radix Bupleuri 25-70 part Herba Artemisiae Scopariae 25-65 part
Scolopendra 2-7 part Scorpio 2-7 part
Elderly woman hair 15-30 part
The oily 168-670 part milk of little mill 102-359 part
Above-mentioned each component is made this medicine production method is: 1. Moschus, the bovine calculus powder of getting defined amount in the prescription are broken to 100-120 purpose fine powder.2. get the Fructus Crotonis of ormal weight 1/2-3/4 in the prescription, Bai Ren is continued to employ in its peeling, take by weighing Resina Ferulae, the Sanguis Draxonis of ormal weight 1/2-3/4 in the prescription again, take by weighing Fructus Amomi, Herba Artemisiae Scopariae, Radix Bupleuri by formula ratio again, these medicines are crushed to 100-120 order fine powder jointly.3. the fine powder that is processed into for twice is lumped together, and mix homogeneously.4. be split on the cloth after modulating evenly with milk above-mentioned medicated powder cure use to patient before, make living plaster, every living plaster is the 100-200 gram, and medicine spreads diameter 10-15 centimetre.5. take by weighing Fructus Crotonis, Sanguis Draxonis, the Resina Ferulae of ormal weight 1/4-1/2 in Semen Momordicae, Resina garciniae, Squama Manis, Scorpio, Scolopendra, elderly woman hair, little mill oil and the batching of ormal weight in the prescription.6. the heating of little mill oil is then added above-mentioned nine kinds of medicines respectively, whole medicine boil that temperature is controlled between 80 ℃-320 ℃ in the process, boiled about 24 hours, and can pull silk, and speed is pulled when continuous when what medicine was endured, stop heating, this medicine is split on the cloth, makes plaster, this plaster is ripe plaster, every plaster weighs 100 grams-200 grams, diameter 10-15 centimetre.
The best preparing process of this plaster is: pair give birth to the used milk of plaster modulation with people's the best of suckling 1..2. the heating means that ripe plaster is boiled adopt the wave heating means, and it is earlier little mill oil to be heated to 100 ℃ that the adding of medicine adds by different temperature, add Semen Momordicae this moment.Continue heating, when temperature rises to 200 ℃, add Scolopendra, Scorpio, the elderly woman hair is heated to 300 ℃ then, adds Fructus Crotonis, Resina garciniae.Reheat and make its temperature that boils medicine reduce to 200 ℃ not when temperature rises to 300 ℃, reduce to 100 ℃ again, reheat makes it be warmed up to 200 ℃ when reducing to 100 ℃, be warmed up to 300 ℃ again, then wave descends again, to keep this temperature 5-10 minute at each temperature section, carry out so repeatedly, be about 24 hours heat time heating time.Can pull silk until what medicine boiled, and speed is pulled and is stopped to heat when continuous.
Earlier clear up the hepatic region during treatment with Rhizoma Zingiberis Recens, the living plaster that to make again applies, used 4-8 hour, the medicine of exhausted living plaster can add milk and repeat reuse, to patient's continuous use time be 8 days, then had a rest seven days, every two weeks is a course of treatment, grasp to need the number course of treatment of treatment according to the state of an illness, in the end patient need paste and use ripe plaster in course of treatment.
Therefore adopt this kind Drug therapy hepatopathy, removed the hardship that patient takes medicine from, medicine directly is affixed on the hepatic region of clearing up through Rhizoma Zingiberis Recens, is convenient to the infiltration of medicine and to the treatment of hepatopathy.
In order to show the therapeutic effect of the present invention to hepatopathy, from 1992-1997 the present invention 1535 routine patients have been carried out clinical observation, male patient 1309 people wherein, female patient 226 people, by age be grouped into: 53 people below 20 years old, 21-35 year 428 people, 36-50 year 409 people, 51-60 year 132 people, 313 people more than 60 years old; Be grouped into by medical history: the patient below 8 years is 789 people, and the patient of 8-15 is 624 people, and the patient is 110 people more than 15 years; Be grouped into by sick type: first type 189 people, B-mode 1229 people, fatty liver 12 people, non-first, non-B-mode 109 people.The patient that above-mentioned patient is examination in hospital, makes a definite diagnosis.
The medicine of other any treatment hepatopathys of stopping using during the treatment only pastes and uses drug prepared of the present invention.
The treatment situation is:
| Liver disease types | The first type | B-mode | Non-first, B-mode |
| The treatment number | ????189 | ????1229 | ????109 |
| The healing number | ????187 | ????1204 | ????106 |
| Cure rate (%) | ????99 | ????98 | ????97 |
The treatment standard is:
1. disease disappears.
2. the hepatic region does not have tenderness or percussion pain.
3. the Inspection Certificate liver function recovery is normal.
4. hepatitis b liver disease patient HBeAg turns out cloudy.
Above-mentioned patient is carried out in the therapeutic process, after using the present invention 5 courses of treatment,, draws patient's inquiry: all patients no longer include weak, feel sick, detest subjective symptomss such as oil, abdominal distention, hepatalgia, the diet sleep recovers normal.
In treatment, 205 hepatitis B patients are carried out follow-up investigations, using this invention Drug therapy after 4 months, on inspection: the HBeAg person of turning out cloudy 152 examples, account for 74.15%, all the other all decrease, hepatomegaly is recovered normal person's 179 examples, accounts for 87.32%, and all the other all have dwindles.
Embodiment 1:
Take by weighing raw material by following prescription and proportioning:
0.2 kilogram of 0.5 kilogram of Calculus Bovis of Moschus
7.5 kilograms of 7.5 kilograms of Sanguis Draxonis of Resina Ferulae
7.5 kilograms of 7.5 kilograms of Semen Sinapis Albaes of Fructus Crotonis
10 kilograms of 11 kilograms of Squama Maniss of Semen Momordicae
8.5 kilograms of 0.9 kilogram of Resina garciniaes of Fructus Amomi
7.5 kilograms of 8 kilograms of Herba Artemisiae Scopariaes of Radix Bupleuri
0.7 kilogram of 0.35 kilogram of Scorpio of Scolopendra
4 kilograms in elderly woman hair
36 kilograms of 53 kilograms of milk of little mill oil
Make as follows: 1. the preparation of giving birth to plaster:
Moschus, bovine calculus powder by required amount in the prescription are broken to 100 purpose fine powders; get 3/5 of Fructus Crotonis weight in the prescription; Bai Ren is continued to employ in its peeling; take by weighing 3/5 of Resina Ferulae and Sanguis Draxonis weight in the prescription; take by weighing Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription; they are crushed to 100 purpose fine powders jointly; then the fine powder mix homogeneously that is processed into for twice; said medicine is then spread out on cloth with the milk mediation of amount in the prescription; make living plaster; every living plaster content of dispersion is 200 grams, and the plaster diameter is 15 centimeters, is in harmonious proportion with milk and carries out before operation is used.2. the manufacturing of ripe plaster:
Take by weighing Fructus Crotonis, Sanguis Draxonis and the Resina Ferulae of ormal weight 2/5 in Semen Momordicae, Resina garciniae, Squama Manis, Scorpio, Scolopendra, elderly woman hair and the prescription by ormal weight in the prescription, take by weighing the little mill oil of measuring in the prescription, be heated to 80 ℃, put into Semen Momordicae, continue heating again and progressively put into Scolopendra, Scorpio, elderly woman hair, Squama Manis, Resina Ferulae, Sanguis Draxonis, Fructus Crotonis and Resina garciniae.Be heated to 320 ℃ when spending when boiling temperature, stop to heat and temperature is descended gradually, decline must not be lower than 80 ℃, after temperature descends, heat again and make its rising, the whole temperature that boils remains between 80 ℃-320 ℃, and about 24 hours of the time that boils, extremely the thing of decocting medicinal herbs can pull silk, cutting speed pulls and stops to heat when continuous, the above-mentioned medicine that boils is shared on cloth, made plaster, claim that this is ripe plaster, every plaster weighs 100 grams, 15 centimeters of its plaster diameters.
Embodiment 2
Take by weighing raw material by following proportioning:
0.1 kilogram of 0.25 kilogram of Calculus Bovis of Moschus
6 kilograms of 6 kilograms of Sanguis Draxonis of Resina Ferulae
4.5 kilograms of 5 kilograms of Semen Sinapis Albaes of Fructus Crotonis
8 kilograms of 6.5 kilograms of Squama Maniss of Semen Momordicae
15 kilograms of 0.25 kilogram of Resina garciniaes of Fructus Amomi
2.9 kilograms of 4 kilograms of Herba Artemisiae Scopariaes of Radix Bupleuri
0.3 kilogram of 0.7 kilogram of Scorpio of Scolopendra
2 kilograms in elderly woman hair
60 kilograms of people of little mill oil suckle 20 kilograms
Preparation as follows: 1. Moschus, bovine calculus powder by required amount in the prescription are broken to 120 purpose fine powders; half peeling with Fructus Crotonis weight in the prescription; continue to employ Bai Ren; take by weighing 1/2 of Resina Ferulae and Sanguis Draxonis weight in the prescription; take by weighing Fructus Amomi, Herba Artemisiae Scopariae, the Radix Bupleuri of ormal weight in the prescription again; they are crushed to 120 purpose fine powders jointly; then the fine powder mix homogeneously that is processed into for twice; the powder that said medicine is made is suckled with the people of ormal weight in the prescription and is in harmonious proportion evenly before use; spread out on cloth; make living plaster, its medicine diameter is 12 centimeters, and weight is 100 grams.2. take by weighing Fructus Crotonis, Sanguis Draxonis and the Resina Ferulae of ormal weight 1/2 in Semen Momordicae, Resina garciniae, Squama Manis, Scorpio, Scolopendra, elderly woman hair, little mill oil and the prescription by ormal weight in the prescription, earlier little mill oil is heated to 100 ℃ and puts into Semen Momordicae, continue to be heated to 200 ℃ again, add Scolopendra, Scorpio, elderly woman hair this moment, and then continue to be heated to 300 ℃, add Fructus Crotonis, Resina garciniae this moment.Reheat not when temperature rises to 300 ℃, and make its temperature that boils medicine reduce to 200 ℃, reduce to 100 ℃ again, reheat when reducing to 100 ℃, it is risen again, rise to 200 ℃ by 100 ℃ and rise to 300 ℃ again, then wave descends again, and rising at every turn or drop to each temperature section will keep this temperature 10-15 minute, carry out so repeatedly, be about 24 hours heat time heating time, boil until medicine and can pull silk, cut speed and pull and stop to heat when continuous.Then, the medicine that boils is shared on paper or cloth, made ripe plaster, ripe plaster diameter is 12 centimeters, and weight is 200 grams.
Claims (6)
1. Tongguanshugan ointment for the treatment of hepatopathy, it is characterized in that: it has following medicine and component to be prepared from: (consumption is a weight portion)
Moschus 0.5-5 part Calculus Bovis 0.3-3 part
Resina Ferulae 20-90 part Sanguis Draxonis 20-90 part
Fructus Crotonis 15-80 part Semen Sinapis Albae 15-80 part
Semen Momordicae 35-120 part Squama Manis 20-120 part
Fructus Amomi 1.5-9 part Resina garciniae 50-180 part
Radix Bupleuri 20-80 part Herba Artemisiae Scopariae 20-80 part
Scolopendra 2-8 part Scorpio 2-8 part
Elderly woman hair 10-40 part
The oily 140-910 part milk of little mill 84-496 part
2. the Tongguanshugan ointment of treatment hepatopathy according to claim 1 is characterized in that: medicine that it is contained and consumption weight portion are:
Moschus 0.8-3 part Calculus Bovis 0.5-2 part
Resina Ferulae 20-60 part Sanguis Draxonis 20-60 part
Fructus Crotonis 20-50 part is from Semen Sinapis 20-50 part
Semen Momordicae 40-85 part Squama Manis 25-100 part
Fructus Amomi 1.5-7 part Resina garciniae 60-150 part
Radix Bupleuri 25-70 part Herba Artemisiae Scopariae 25-65 part
Scolopendra 2-7 part Scorpio 2-7 part
Elderly woman hair 15-30 part
The oily 168-670 part milk of little mill 102-59 part
3. the preparation method of the Tongguanshugan ointment of treatment hepatopathy according to claim 1 and 2 is characterized in that:
This plaster is formed for two kinds by giving birth to plaster and ripe plaster.
The preparation method of giving birth to plaster is:
A. Moschus, the bovine calculus powder of getting defined amount in the prescription are broken to 100-120 purpose fine powder;
B. get the Fructus Crotonis of ormal weight 1/2-3/4 in the prescription again, Bai Ren is continued to employ in its peeling, take by weighing Resina Ferulae, the Sanguis Draxonis of ormal weight 1/2-3/4 in the prescription again, take by weighing Fructus Amomi, Herba Artemisiae Scopariae, Radix Bupleuri by formula ratio again, they are crushed to 100-120 order fine powder jointly;
C. the fine powder that is processed into for twice is lumped together, and mix homogeneously.Cure use to patient before, will go up
State the milk modulation of medicated powder, and spread out on cloth, make living plaster with ormal weight in the prescription; The preparation method of ripe plaster is:
E takes by weighing Fructus Crotonis, Sanguis Draxonis, the Resina Ferulae of ormal weight 1/4-1/2 in Semen Momordicae, Resina garciniae, Squama Manis, Scorpio, Scolopendra, elderly woman hair, little mill oil and the batching of ormal weight in the prescription, with the heating of little mill oil, then add above-mentioned nine kinds of medicines respectively, medicine boils that temperature is controlled between 80 ℃-320 ℃ in the process, boils about 24 hours, can pull silk when medicine is boiled into, and speed is pulled when continuous, stop to heat, this medicine is split on the cloth, make ripe plaster.
4. according to the preparation method of the described Tongguanshugan ointment of claim 4, it is characterized in that: the weight of every plaster is the 100-200 gram, and it is the 10-15 centimetre that its plaster medicine spreads diameter.
5. the preparation method of Tongguanshugan ointment according to claim 3 is characterized in that: earlier little mill oil is heated to 100 ℃ when ripe plaster is boiled, add Semen Momordicae this moment.Continue heating, when rising to 200C, temperature adds Scolopendra, Scorpio, the elderly woman hair, be heated to 300 ℃ then, add Fructus Crotonis, Resina garciniae, reheat and make its temperature that boils medicine reduce to 200 ℃ not when temperature rises to 300 ℃ is reduced to 100 ℃ again, reheat makes it be warmed up to 200 ℃ when reducing to 100 ℃, be warmed up to 300 ℃ again, then wave descends again, and rising at every turn or drop to each temperature section will keep this temperature 10-15 minute, carry out so repeatedly, be about 24 hours heat time heating time, boil until medicine and can pull silk, and speed is pulled and stopped to heat when continuous.
6. the preparation method of Tongguanshugan ointment according to claim 5 is characterized in that: preparation is given birth to the used milk of plaster and is suckled for the people.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98104834A CN1088370C (en) | 1998-01-15 | 1998-01-15 | Tongguanshugan ointment and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98104834A CN1088370C (en) | 1998-01-15 | 1998-01-15 | Tongguanshugan ointment and preparation process thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001160486A Division CN1150919C (en) | 2000-09-22 | 2000-09-22 | Paste for eradicating liver disease and preparing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1223127A true CN1223127A (en) | 1999-07-21 |
| CN1088370C CN1088370C (en) | 2002-07-31 |
Family
ID=5218497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98104834A Expired - Fee Related CN1088370C (en) | 1998-01-15 | 1998-01-15 | Tongguanshugan ointment and preparation process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1088370C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406859A (en) * | 2011-12-01 | 2012-04-11 | 张玉芹 | External traditional Chinese medicine composition for treating hepatitis B |
| CN109125415A (en) * | 2018-11-03 | 2019-01-04 | 杜文建 | A kind of external application Chinese medicine patch and preparation method thereof for treating hepatopathy |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1063819A (en) * | 1991-02-05 | 1992-08-26 | 王柱亭 | Formula of Kezeng ointment |
| CN1076628A (en) * | 1993-02-12 | 1993-09-29 | 宋美琼 | Yuer ointment |
-
1998
- 1998-01-15 CN CN98104834A patent/CN1088370C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406859A (en) * | 2011-12-01 | 2012-04-11 | 张玉芹 | External traditional Chinese medicine composition for treating hepatitis B |
| CN102406859B (en) * | 2011-12-01 | 2014-07-23 | 张玉芹 | External traditional Chinese medicine composition for treating hepatitis B |
| CN109125415A (en) * | 2018-11-03 | 2019-01-04 | 杜文建 | A kind of external application Chinese medicine patch and preparation method thereof for treating hepatopathy |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1088370C (en) | 2002-07-31 |
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