CN1091382C - Compound Lingxian headache-treating capsule and its preparation - Google Patents
Compound Lingxian headache-treating capsule and its preparation Download PDFInfo
- Publication number
- CN1091382C CN1091382C CN99119582A CN99119582A CN1091382C CN 1091382 C CN1091382 C CN 1091382C CN 99119582 A CN99119582 A CN 99119582A CN 99119582 A CN99119582 A CN 99119582A CN 1091382 C CN1091382 C CN 1091382C
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicine
- radix angelicae
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a novel medicine for treating angioneurotic headache, namely a clematis root headache capsule. Clematis root, chuanxiong rhizome, angelica dahurica, angelica root, cocculus trilobus, asarum herb, grassleaf sweetflag rhizome, scorpion and borneol are used as raw materials. The medicine is prepared by the processes of sieving, pulverizing, boiling in water, extracting with alcohol, drying, mixing after trituration, and encapsulating according to different characteristics of the traditional Chinese medicines. The present invention has the advantages of unique formula, scientific and reasonable preparing method and significant clinical effect.
Description
The present invention relates to a kind of medicine for the treatment of angioneurotic headache, is the Chinese patent medicine of feedstock production with the natural animal-plant medicine specifically, the invention still further relates to the preparation method of this medicine.
Angioneurotic headache is the cephalagia that a kind of vasomotor dysfunction causes, is that clinical common multiple disease accounts for 55～76% of Neurology Clinic, and outbreak repeatedly, and touching difficulty is more brought huge misery to the patient.
Western modern medicine treatment primary disease does not still have desirable method and medicine at present, though can use caffeine Ergotamine and so on, can only be to stop once taking place yet, and each medication must get the jump on before the headache outbreak, otherwise invalid, toxicity is big in addition, easy addiction can not life-time service.Though though some Chinese and Western patent medicine of listing are effective successively in recent years, and because of the effect shakiness, on the high side and not suffered by the patient.
The object of the present invention is to provide a kind of quick-acting, efficient, long-acting, have no side effect not addiction, new drug that dosage is little, inexpensive.Prove through clinical and experimental study: it has the merit by cold collateral dredging, blood circulation promoting and blood stasis dispelling, dehumidifying eliminating phlegm, sensible analgesia; Have anti-platelet aggregation, suppress platelet release reaction, the fortifying fibre protein dissolution, blood viscosity lowering, blood flow increasing, blood vessel dilating, microcirculation improvement has stronger calmness, analgesic activity.Meet the requirement of World Health Organization (WHO), be available as the ideal medicament of prophylactic treatment angioneurotic headache treatment angioneurotic headache new drug.
Solution of the present invention is based on the Chinese and Western pharmacy pathogenetic understanding of angioneurotic headache and the author are summed up the treatment viewpoint that proposes new " control blood is controlled wind earlier, wind is dehematized from logical " through secular clinical observation, according to the folk remedy experience, clinical research practice in conjunction with for many years filters out from the Chinese medicine treasure-house; By cold collateral dredging, blood circulation promoting and blood stasis dispelling, dehumidifying eliminating phlegm, the pure natural animals and plants of sensible analgesia, press the Chinese medical theory prescription, the utilization modern science and technology, extract the medicine active ingredient, make its performance stronger blood vessel dilating, calmness, analgesic activity, be used for the pure compound Chinese medicinal preparation of treatment of vascular nervous headache.
Another object of the present invention provides the preparation method of this medicine
Medicine of the present invention is made (consumption is a weight portion) by following prescription
12～18 parts of 12～20 parts of Rhizoma Chuanxiongs of Radix Clematidis
8～16 parts of 10～18 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
6～12 parts of 10～18 parts of Herba Asaris of Radix cocculi laurifolii
6～12 parts of 10～18 portions of Scorpios of Rhizoma Acori Graminei
6～10 parts of Borneolum Syntheticums
The formula optimization weight proportion scope of preparation medicine of the present invention is
10～18 parts of 12～18 parts of Rhizoma Chuanxiongs of Radix Clematidis
8～12 parts of 8～16 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
6～10 parts of 8～16 parts of Herba Asaris of Radix cocculi laurifolii
6～8 parts of 8～16 portions of Scorpios of Rhizoma Acori Graminei
6～8 parts of Borneolum Syntheticums
The optimum weight proportioning of medicine of the present invention is
16 parts of 16 parts of Rhizoma Chuanxiongs of Radix Clematidis
10 parts of 12 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
8 parts of 12 parts of Herba Asaris of Radix cocculi laurifolii
6 parts of 12 portions of Scorpios of Rhizoma Acori Graminei
6 parts of Borneolum Syntheticums
Above-mentioned each component is made medicine production method of the present invention is:
1, batching: the qualified weighing of the process of preparing Chinese medicine of will adding medicine to by writing out a prescription is assorted, and each prescription is put.
2, pulverize: get the Radix Angelicae Dahuricae and roll into that fine powder is crossed 120 order dusting cover (making absorbent) Scorpios, borneol and grinding becomes fine powder, the proportion of goods damageds 5%, it is standby that Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei, Radix cocculi laurifolii, Radix Clematidis roll into No. 4 coarser powder respectively.
3, carry oil, get Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei, add water 10-12 in the extractor respectively and doubly measure, be heated to boil and keep slight boiling condition to carry oil fully till (carry the about Rhizoma Chuanxiong 1% of oil mass, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei each 0.8%) reservation medicinal liquid and medicinal residues.
4, alcohol extraction: get the medicinal liquid of carrying behind the oil and merge concentrating under reduced pressure and become thick paste, add 95% ethanol precipitation and filter, filtrate recycling ethanol, medicinal liquid concentrates 80 ℃ of oven dry, and porphyrize gets extract powder.
5, water is carried: the medicinal residues after getting Radix Clematidis, Radix cocculi laurifolii and carrying oil add 12 times of amounts of water, decocting in water 2 times, and each 1.5 hours, merge the water extract, filter, filtrate is condensed into thick paste.
6, mix: get 2/3 Radix Angelicae Dahuricae powder and 5 water and carry cream and stir 80 ℃ and be dried and crushed into fine powder, volatile oil and the absorption of remaining Radix Angelicae Dahuricae powder are ground into fine powder, get Scorpio powder extract powder and above-mentioned two kinds of medicated powder, mix homogeneously adds Borneolum Syntheticum, and fully mix homogeneously divides encapsulated.Every 0.3g.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, choice of drug natural animal of the present invention, plant are raw material, and each component meets the pharmaceutical control law regulation, utilize the comprehensive function treatment angioneurotic headache of the Chinese medicine of respectively distinguishing the flavor of.
2, medicine of the present invention can be eliminated headache and simultaneous phenomenon thereof rapidly.
3, medicine of the present invention does not have GI irritation effect, better tolerance.
4, medicine of the present invention does not have obvious liver, kidney, and the blood side effect is safe.
5, medicine of the present invention is easy to use, reasonable price, no addiction.
6, medicine of the present invention is right, and having a headache behind vascular, nerve, migraine, the cerebral trauma etc. all has good effect.
For showing the therapeutic effect of medicine of the present invention to angioneurotic headache, through the clinical observation of 120 routine systems, and select the suitable angioneurotic headache patient of medical history, the state of an illness, the course of disease, age, sex and Therapeutic Method 60 examples to carry out controlled observation at random for matched group, select case by " practical internal medicine " (1986 the 8th editions) (angioneurotic headache) diagnostic criteria and tcm diagnosis standard.
1, headache outbreak repeatedly, or persistence headache, ictal increasing the weight of with feeling sick.The headache position: how at head one side volume temporo, forehead, mountain peak top, or a left side or the right side toss about in bed outbreak, or full headache.Headache character: jumping pain, twinge, distending pain, dull pain, dusk pain or headache as split etc.The headache frequency: the sustainable several the number of minutes hour of showing effect, also has lasting several weeks at a couple of days.1) but the sick inducement of sending out does not have premonitory symptom before the outbreak.2) women is more.3), do organic disease causer in CT, MRI, DSA inspection eliminating cranial injury and the brain in case of necessity through nervous system and physico-chemical examination.
2, differential diagnosis in tcm: wind and cold is detained, phlegm stagnation in collateral: headache, and outbreak is not repeatedly prolongedly healed, and the inclined to one side side of pain is left or right, localized pain, gesture such as acupuncture, companion's vomiting and nausea sputum, the dim greasy fur stringy and thready pulse of chest distress body of the tongue purple is puckery.
3, get rid of the case standard: 1) all because of the caused headache of organic disease patients such as intracranial space-occupying lesion head organs.2) serious former expectorant disease of conscience, kidney and hemopoietic system, psychotic, allergic constitution.3) under-18s, over-65s, gestation or women breast-feeding their children.
4, include the case standard in: allly be diagnosed as headache, and meet differential diagnosis in tcm standard person.
Case 180 examples are observed in treatment altogether, are divided into 2 groups at random, and 120 examples are organized in treatment, wherein male 38 examples, and women 82 examples, 37.5 years old mean age, the course of disease is the shortest 3 months, and is the longest 21 years, average 3.5 years; Unusual person's 98 examples of rheoencephalogram inspection account for 81.6%.Matched group 60 examples, male 19 examples, women 41 examples, at 36.7 years old age, the course of disease is the shortest 3 months, and is the longest 20 years, and average 3.2 years, wherein unusual person's 47 examples of cerebral blood flow accounted for 78.3%.
Therapeutic Method: oral Lingxian headache-treating capsule is organized in treatment, one time 2～4,2 times on the one, 30 days 1 courses of treatment.1 6.0g of matched group KOUFU ZHENGTIAN WAN (Nanfang Pharmaceutical Factory's production), 3 times on the 1st, 30 days 1 courses of treatment.During treating, withdraw other medicines.Evaluate curative effect after 1 course of treatment, all take a blood sample before all patient treatments and check platelet count (PLT) platelet aggregation (PAP), platelet adhesion rate (PAR) and rheoencephalogram; Blood, routine urinalysis, electrocardiogram, liver, renal function and untoward reaction.All therapeutic outcomes adopt X
2Check and t check.
Curative effect determinate standard: cure: headache and simultaneous phenomenon disappear, and it is normal that rheoencephalogram recovers, and follows up a case by regular visits to and do not have recurrence half a year; Produce effects; Headache and simultaneous phenomenon disappear, and rheoencephalogram recovers normal recurrence half a year, effectively; Headache and simultaneous phenomenon alleviate, and rheoencephalogram improves; Invalid; Headache and simultaneous phenomenon do not have improvement, the rheoencephalogram no change.
Therapeutic outcome:
1, according to The above results standard rating therapeutic outcome, treatment group cure rate and total effective rate all obviously are better than contrast (P＜0.01) and see Table I.
The clinical total effects of Table I relatively
·P＜0.01
| Divide into groups routine number healing produce effects (%) (%) | Effectively (%) | Invalid (%) | Total effective rate (%) |
| 120 78 (65) 29 (24.2) matched groups 60 18 (30) 17 (28.3) are organized in treatment | 10.(8.3) 11(183) | 3(2.5) 14(23.3) | 117(97.5)· 46(76.7) |
2, by onset time after the observation medication, there is significant difference treatment group and matched group comparison P＜0.05, and aspect analgesic time, two groups of comparisons (P＜0.01) have significant differences, and the treatment group is better than matched group.
See Table II
Two groups of onset times of Table II, analgesic time is (X ± S) relatively
| Grouping | The example number | Onset time/min | Analgesic time/h |
| Treatment group matched group | 120 60 | 25.63±538· 5923±8.83 | 23.16±5.94·· 91.45±9.78 |
Compare P＜0.05 P＜0.01 with matched group
3, two groups to patient's cerebral blood flow blood supply insufficiency, and vascular resistance is big, and abnormal phenomenas such as poor flexibility and slow blood flow all have different improvement.Compare P＜0.05 before and after two groups of treatments, significant difference is arranged, treatment group and treatment of control group relatively have significant difference in P＜0.01.See Table III
Two groups of cerebral blood flow of Table III change situation
| Project | Group | Before the treatment | The treatment back is normal | No change | Improvement rate (%) |
| Blood supply insufficiency vascular resistance trunk elastic force difference slow blood flow | Treatment group treatment of control group group treatment of control group group treatment of control group group control group | 32 16 21 12 27 9 18 8 | 23 9 13 5 20 4 15 4 | 9 9 8 7 7 5 3 4 | 71.8 50.0 61.9 41.6 74.0 44.4 83.3 50.0 |
4, by clinical proof medicine of the present invention tangible reduction blood viscosity, anticoagulant effect are arranged.See Table IV
PLT, PAP before and after the treatment of two groups of Table IV, the comparison of PAR value (X ± S)
| Group | PLT( x10 9/L) | PAP(％) | PAR(％) |
| After treating before matched group (60) is treated after treating before treatment group (120) is treated | 221.5±263 208.6±1.87 211.7±28.5 203.0±27.3 | 28.13±1.91 21.21±1.05 27.57±1.83 26.34±1.21 | 7.41±0.78 5.03±10.4 7.03±0.84 6.92±9.73 |
Annotate: compare P＜0.01 before treating with this group, treat the back relatively with matched group
P＜0.01
Show that from above-mentioned therapeutic outcome medicine of the present invention has by cold collateral dredging blood circulation promoting and blood stasis dispelling, dehumidifying eliminating phlegm, sensible analgesic effect.Total effective rate 97.5%, total cure-remarkable-effectiveness rate 89.2%; And all be better than matched group aspect onset time and the analgesic time, and the time brain blood unusual patient improve significantly, clinical practice is safe and reliable.Therefore, medicine of the present invention has good preventing and therapeutical effect to angioneurotic headache, can be used as one of angioneurotic headache patient choice drug, has certain popularization value.
Embodiment
Take by weighing raw material by following proportional quantity
Radix Clematidis 680g Rhizoma Chuanxiong 660g Radix Angelicae Sinensis 560g
Radix Angelicae Dahuricae 380g Herba Asari 120g Radix cocculi laurifolii 560g
Rhizoma Acori Graminei 480g Scorpio 120g Borneolum Syntheticum 108g production method is as follows:
Batching: the qualified weighing of the process of preparing Chinese medicine of will adding medicine to by writing out a prescription is assorted, and each prescription is put; Pulverize; Get the Radix Angelicae Dahuricae and roll into fine powder and cross 120 order dusting covers, make absorbent, Scorpio, borneol and grinding become fine powder, the proportion of goods damageds 5%, and it is standby that Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei, Radix cocculi laurifolii, Radix Clematidis roll into No. 4 coarser powder respectively; Carry oil; Get Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, SHIGEPU, put and add water 10-12 in the extractor and doubly measure respectively, be heated to boil and keep slight boiling condition to carry oil fully till, carry the about Rhizoma Chuanxiong 1% of oil mass, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei each 0.8%, reservation medicinal liquid and medicinal residues; Alcohol extraction: get the medicinal liquid of carrying behind the oil and merge concentrating under reduced pressure and become thick paste, add 95% ethanol precipitation and filter, filtrate recycling ethanol, medicinal liquid concentrates 80 ℃ of oven dry, and porphyrize gets extract powder; Water is carried: the medicinal residues after getting Radix Clematidis, Radix cocculi laurifolii and carrying oil add 12 times of amounts of water, decocting in water 2 times, and each 1.5 hours, merge the water extract, filter, filtrate is condensed into thick paste; Mix: get 2/3 Radix Angelicae Dahuricae powder and carry cream with water and stir, 80 ℃ are dried and crushed into fine powder, volatile oil and the absorption of remaining Radix Angelicae Dahuricae powder, be ground into fine powder, get Scorpio powder cream powder and above-mentioned two kinds of medicated powder, mix homogeneously adds Borneolum Syntheticum, abundant mix homogeneously, divide encapsulated, every 0.3g.
Claims (6)
1, a kind of medicine for the treatment of angioneurotic headache is characterized in that it being the medicament of being made by following materials of weight proportions
12～18 parts of 12～20 parts of Rhizoma Chuanxiongs of Radix Clematidis
8～16 parts of 10～18 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
6～12 parts of 10～18 parts of Herba Asaris of Radix cocculi laurifolii
6～12 parts of 10～18 portions of Scorpios of Rhizoma Acori Graminei
6～10 parts of Borneolum Syntheticums
2, according to the medicine of the described treatment angioneurotic headache of claim 1, the weight proportion of raw material wherein is
10～18 parts of 12～18 parts of Rhizoma Chuanxiongs of Radix Clematidis
8～12 parts of 8～16 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
6～10 parts of 8～16 parts of Herba Asaris of Radix cocculi laurifolii
6～8 parts of 8～16 portions of Scorpios of Rhizoma Acori Graminei
6～8 parts of Borneolum Syntheticums
3, according to the medicine of the described treatment angioneurotic headache of claim 1, wherein the weight proportion of each raw material is
16 parts of 16 parts of Rhizoma Chuanxiongs of Radix Clematidis
10 parts of 12 parts of Radix Angelicae Sinensis of the Radix Angelicae Dahuricae
8 parts of 12 parts of Herba Asaris of Radix cocculi laurifolii
6 parts of 12 portions of Scorpios of Rhizoma Acori Graminei
6 parts of Borneolum Syntheticums
4,, it is characterized in that said medicament is said any dosage form in the pharmaceutics according to the medicine of claim 1,2 or 3 described treatment angioneurotic headaches.
5,, it is characterized in that said dosage form is a hard capsule according to the medicine of the described treatment angioneurotic headache of claim 4.
6, the preparation method of the medicine of the described treatment angioneurotic headache of claim 5 is characterized in that: batching: the qualified weighing of the process of preparing Chinese medicine of will adding medicine to by writing out a prescription is assorted, and each prescription is put; Pulverize; Get the Radix Angelicae Dahuricae and roll into fine powder and cross 120 order dusting covers and make absorbent, Scorpio, borneol and grinding become fine powder, the proportion of goods damageds 5%, and it is standby that Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei, Radix cocculi laurifolii, Radix Clematidis roll into No. 4 coarser powder respectively; Carry oil; Get Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei, put and add water 10-12 in the extractor and doubly measure respectively, be heated to boil and keep slight boiling condition to carry oil fully till, carry the about Rhizoma Chuanxiong 1% of oil mass, Radix Angelicae Sinensis, Herba Asari, Rhizoma Acori Graminei each 0.8%, reservation medicinal liquid and medicinal residues; Alcohol extraction: get the medicinal liquid of carrying behind the oil and merge concentrating under reduced pressure and become thick paste, add 95% ethanol precipitation and filter, filtrate recycling ethanol, medicinal liquid concentrates 80 ℃ of oven dry, and porphyrize gets extract powder; Water is carried: the medicinal residues after getting Radix Clematidis, Radix cocculi laurifolii and carrying oil add 12 times of amounts of water, decocting in water 2 times, and each 1.5 hours, merge the water extract, filter, filtrate is condensed into thick paste;
Mix: get 2/3 Radix Angelicae Dahuricae powder and carry cream with water and stir, 80 ℃ are dried and crushed into fine powder, volatile oil and the absorption of remaining Radix Angelicae Dahuricae powder, be ground into fine powder, get Scorpio powder, extract powder and above-mentioned two kinds of medicated powder, mix homogeneously adds Borneolum Syntheticum, abundant mix homogeneously, divide encapsulated, every 0.3g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99119582A CN1091382C (en) | 1999-09-08 | 1999-09-08 | Compound Lingxian headache-treating capsule and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99119582A CN1091382C (en) | 1999-09-08 | 1999-09-08 | Compound Lingxian headache-treating capsule and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1287005A CN1287005A (en) | 2001-03-14 |
| CN1091382C true CN1091382C (en) | 2002-09-25 |
Family
ID=5280970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99119582A Expired - Fee Related CN1091382C (en) | 1999-09-08 | 1999-09-08 | Compound Lingxian headache-treating capsule and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1091382C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405727A (en) * | 2013-08-29 | 2013-11-27 | 黄平县润发药业农民专业合作社 | Medicinal liquor for activating blood circulation and relieving headache |
| CN107648402A (en) * | 2017-11-01 | 2018-02-02 | 林恒 | A kind of Chinese and Western compound preparation for treating refractory headache and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1161212A (en) * | 1996-12-25 | 1997-10-08 | 刘晖 | Traditional Chinese medicinal powder for treating headache and method for preparing same |
| CN1175412A (en) * | 1996-09-01 | 1998-03-11 | 夏宗发 | Toothache preparation |
-
1999
- 1999-09-08 CN CN99119582A patent/CN1091382C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175412A (en) * | 1996-09-01 | 1998-03-11 | 夏宗发 | Toothache preparation |
| CN1161212A (en) * | 1996-12-25 | 1997-10-08 | 刘晖 | Traditional Chinese medicinal powder for treating headache and method for preparing same |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1287005A (en) | 2001-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1061854C (en) | Medicinal preparation for treatment and prevention of gynopathy | |
| CN1051237C (en) | Meicinal prepn. "Kexianling" for curing epilepsy | |
| CN101361872A (en) | Traditional Chinese medicine for quickly treating bone fracture and postoperative nonunion and delayed healing | |
| CN103393966B (en) | A kind of Chinese medicine composition for the treatment of menoxenia | |
| CN1302796C (en) | Traditional Chinese medicament for treating woman subhealthy faligue syndrome and its preparation method | |
| CN1695682A (en) | External use preparation for treating rheumatisma and bone injuries | |
| CN1091382C (en) | Compound Lingxian headache-treating capsule and its preparation | |
| CN1931276A (en) | Headache treating Chinese medicine composition and its prepn process | |
| CN100579572C (en) | Orally-administered Chinese medicinal composition for treating migraine pain | |
| CN1895489A (en) | Externally-applied medicinef or treating psoriasis | |
| CN1186067C (en) | Medicine for curing acute injury of muscle and tendon and its preparation method | |
| CN1264547C (en) | Preparation of Chinese traditional medicine for treating coronary heart disease and angina as well as preparation method | |
| CN1092968C (en) | Pharmaceuticals for treating outer skin blood vessel diease in cold seasons | |
| CN112206279B (en) | Traditional Chinese medicine composition for treating ventricular arrhythmia and preparation method and application thereof | |
| CN114984160B (en) | Mongolian medicine for treating alcoholic liver disease | |
| CN1544019A (en) | Chinese traditional medicine composition for treating arthralgia syndrome of cervical spondylopathy and its preparation | |
| CN1076622C (en) | Chinese medicine for curing nephritis | |
| CN1127968C (en) | Oral powder medicine Xiaobaisan for treating leukotrichia and its preparation method | |
| CN1246358A (en) | Medical capsule for treating cerebroma and its preparing process | |
| CN1053381C (en) | Drug for promoting puerperal physiological recovery and curing postpartum disease | |
| CN1114420C (en) | Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process | |
| CN1212852C (en) | Medicine for curing cervical spondylopathy | |
| CN1745802A (en) | Plaster for treating pain and prpearation thereof | |
| CN1557365A (en) | Medicine | |
| CN1772221A (en) | Mastosis treating Chinese medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |