CN1114420C - Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process - Google Patents
Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process Download PDFInfo
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- CN1114420C CN1114420C CN00105845A CN00105845A CN1114420C CN 1114420 C CN1114420 C CN 1114420C CN 00105845 A CN00105845 A CN 00105845A CN 00105845 A CN00105845 A CN 00105845A CN 1114420 C CN1114420 C CN 1114420C
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Abstract
The present invention discloses a medicine for treating intractable sciatica and chronic lumbocrural pain and a preparation method thereof. The medicine is prepared by taking garter snake, prepared common monkshood mother root, fleeceflower root, clematis root, cassia twig, ground beeltle, stir-frying pangolin scale, scorpion, centipede, prepared rhizome of rehmannia, white mustard seed, suberect spatholobus, radix achyranthis bidentatae and white peony roots as raw materials. The raw materials in a certain proportion are respectively aired, crushed, dissolved, extracted, etc., according to different characteristics, the processed raw materials are sterilized at a high temperature and prepared into powder, and the powder is encapsulated. The present invention has the advantages of unique formula and preparation method and obvious curative effects.
Description
The present invention relates to a kind of medicine for the treatment of intractable ischias pain, chronic lambago and skelalgia, it is to be the Chinese patent medicine of feedstock production with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Sciatica, lumbago and skelalgia, the intractable ischias that especially is difficult to cure pain, chronic lambago and skelalgia, the serious harm human health influences the labour force, and is commonly encountered diseases, frequently-occurring disease clinically.This disease belongs to traditional Chinese medical science arthromyodynia category, be by wind-cold damp pathogen, numbness with the passing of time, due to the Liver and kidney insufficiency of vital energy and blood.Pathogen lingers on, in muscle arteries and veins, flesh bone so that battalion defend puckery with fixed attention, stagnation of QI-blood, muscles and bones mistake is supported, and shows as intractable lumbago and skelalgia, numbness, contracture, even disability.
The treatment primary disease is not still had desirable medicine both at home and abroad at present, belong to obstinate disease.
1, nonsteroidal antiinflammatory drug, the plain class medicine of corticosteroid, curative effect is not lasting, and side effect is big, and easily forms dependence.
Though it is 2, physical therapy, acupuncture-moxibustion can make sx, undesirable to intractable prolonged illness curative effect.
3, partial closure's indication limitation also can not be effected a radical cure.
Though the Chinese patent medicine of 4 some treatment primary disease to cureless pertinacious disease DeGrain, is difficult to radical cure.
The object of the present invention is to provide a kind of medicament with following effect:
A, eliminate sciatic interstitial neuritis, and can improve the blood circulation around the nerve root, promote the absorption of edema, thereby remove the extrinsic factor of pressuring neural root.To reach the purpose of fundamentally curing.
B, invigorating the liver and kidney, dispelling cold and dampness, resolving blood stasis and dredging collateral, exempt from numbness pain relieving, treating both the principal and secondary aspects of a disease, can impel cureless pain disease to return to normal condition fast.
Another object of the present invention provides the preparation method of this therapeutic agent.
Solution of the present invention is to the pathogenetic understanding principle of arthromyodynia according to Chinese medicine, with reference to modern pharmacological research, from clinical practice side's medicine, filter out have liver and kidney tonifying, the natural Chinese medicines of effects such as bone and muscle strengthening, dispelling cold by warming the meridian, expelling wind and removing dampness, activating blood circulation to dissipate blood stasis, removing obstruction in the collateral to relieve pain.Through clinical checking repeatedly, have strengthening vital QI to eliminate pathogenic factors, promote rehabilitation, recover labour force's effect.
Medicine of the present invention is made (consumption is a weight portion) by following component:
Zaocys 10-30 part Scorpio 5-15 part Scolopendra 1-10 part
5 parts of Radix Aconiti Preparata 1-10 of Squama Manis (processed) 5-15 part Eupolyphaga Seu Steleophaga 5-1 part
Ramulus Cinnamomi 5-15 part Semen Sinapis Albae 10-30 part Radix Rehmanniae Preparata 15-50 part
Radix Paeoniae Alba 10-40 part Radix Polygoni Multiflori Preparata 15-50 part Caulis Spatholobi 15-50 part
Radix Achyranthis Bidentatae 10-25 part Radix Clematidis 5-15 part.
Preparing pharmaceutical formulation preferred weight ratio range of the present invention is:
Zaocys 15-20 part Scorpio 8-15 part Scolopendra 2-8 part
Squama Manis (processed) 8-12 part Eupolyphaga Seu Steleophaga 8-12 part Radix Aconiti Preparata 2-8 part
Ramulus Cinnamomi 8-15 part Semen Sinapis Albae 10-20 part Radix Rehmanniae Preparata 20-40 part
Radix Paeoniae Alba 15-30 part Radix Polygoni Multiflori Preparata 20-40 part Caulis Spatholobi 20-40 part
Radix Achyranthis Bidentatae 12-20 part Radix Clematidis 8-15 part.
The optimum weight proportioning of medicine of the present invention is:
3 parts of 10 parts of Scolopendras of 20 portions of Scorpios of Zaocys
6 parts of 10 parts of Radix Aconiti Preparatas of 10 parts of Eupolyphaga Seu Steleophagas of Squama Manis (processed)
30 parts in 15 parts of Radix Rehmanniaes Preparata of 10 parts of Semen Sinapis Albaes of Ramulus Cinnamomi
30 parts of 30 portions of Caulis Spatholobis of 20 parts of Radix Polygoni Multiflori Preparatas of Radix Paeoniae Alba
10 parts of 15 parts of Radix Clematidis of Radix Achyranthis Bidentatae.
Above-mentioned each component is made medicine production method of the present invention is:
Get Radix Clematidis, Ramulus Cinnamomi, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, Caulis Spatholobi, Radix Achyranthis Bidentatae, Radix Paeoniae Alba pulverizing earlier, extract, discard residue with Diluted Alcohol solution, after extracting solution concentrates, the residue drying; With Zaocys, Radix Aconiti Preparata, Eupolyphaga Seu Steleophaga, Squama Manis (processed), Scorpio, Scolopendra, the air-dry 120 order fine powders that are ground into of Semen Sinapis Albae; To mix with ethanol extraction after the above-mentioned powder drying, carry out ripening under 100-110 ℃ of temperature, sterilization place 30 minutes makes capsule.
Clinical drug of the present invention uses the result to show to have following advantage:
1, to select pure natural plant and animality Chinese medicine for use be raw material in the present invention, utilizes comprehensive function treatment intractable ischias pain, the chronic lambago and skelalgia of various medicines, and no chemicals is nontoxic, harmless to human body in the ormal weight scope.
2, the present invention need not decoct taking convenience.
3, the emphasis of medicine of the present invention is worth and is with the incurable insensitive impediment of the medicine of other similar properties.
4, therapeutic domain is bigger, for rheumatoid arthritis, scapulohumeral periarthritis, hyperosteogeny etc. certain therapeutic effect is arranged also.
5, the characteristics of this Drug therapy effect are that onset is rapid, and efficacy consolidation is difficult for recurrence.
For showing the therapeutic effect of medicine of the present invention to intractable ischias pain, chronic lambago and skelalgia, 100 routine patients are carried out the clinical observation of system, as the treatment group, 50 examples are organized in contrast and are compared.Wherein male 112 examples, women 38 examples, the age is in 19-30 year person's 15 examples, 31-50 year 88 examples, 51-68 year 47 examples.
Diagnostic criteria:
1, clinical is cardinal symptom with the chronic lambago and skelalgia, holds concurrently or symptoms such as double acid precipitation numbness, contracture.Meet the diagnosis of traditional Chinese medical science arthromyodynia.
2, sciatica, " the disease treatment main points and the criterion of therapeutical effect " of writing in 1984 according to Hebei province Department of Public Health.
3, the course of disease is taken other medicines DeGrain person more than half a year.
Get rid of case: the joint is deformity obviously, dysfunction, disability person; Under-18s child and anemia of pregnant woman; Body constitution severe valetudinarian, invalid; Suffers from important organ disease patient simultaneously; Person due to the secondary factors such as lumbar vertebra, myeleterosis and inflammation, tumor, tuberculosis.
The treatment group is withdrawn other medicines, takes medicine of the present invention, obeys 3.0g at every turn, and 3 times on the 1st, 30 days was 1 course of treatment; Matched group uses the lumbago and skelalgia ball, and each 10,2 times on the 1st, serve on for 1 week, withdraw after 3 days and obey again.
Criterion of therapeutical effect: symptom all disappears, and it is normal for curing that functional activity recovers; Cardinal symptom disappears, and functional activity is obviously progressive to be produce effects; Sx, functional activity are progressive to some extent for effective; Symptom function no change is invalid.Clinical treatment the results are shown in following table (1-2)
Table 1 liang group clinical efficacy statistical result
| Grouping | The example number | Cure (%) | Produce effects (%) | Effectively (%) | Invalid (%) |
| The treatment group | 100 | 96(96.00) | 3(3.00) | 1(1.00) | |
| Matched group | 50 | 30(60.00) | 12(24.00) | 3(6.00) | 5(10.00) |
X
2＝17.97 P＜0.001
Table 2 liang group treatment time statistics
| Grouping | The example number | 30 days (%) | 60 days (%) | 90 days (%) |
| The treatment group | 100 | 64(64.00) | 27(27.00) | 9(9.00) |
| Matched group | 50 | 25(50.00) | 17(34.00) | 3(6.00) |
Embodiment:
Take by weighing raw material by following proportioning
3 kilograms of 10 kilograms of Scolopendras of 20 kilograms of Scorpios of Zaocys
6 kilograms of 10 kilograms of Radix Aconiti Preparatas of 10 kilograms of Eupolyphaga Seu Steleophagas of Squama Manis (processed)
30 kilograms in 15 kilograms of Radix Rehmanniaes Preparata of 10 kilograms of Semen Sinapis Albaes of Ramulus Cinnamomi
30 kilograms of 30 kilograms of Caulis Spatholobis of 20 kilograms of Radix Polygoni Multiflori Preparatas of Radix Paeoniae Alba
10 kilograms of 15 kilograms of Radix Clematidis of Radix Achyranthis Bidentatae
Production method is as follows:
Earlier Ramulus Cinnamomi, Radix Polygoni Multiflori Preparata, Caulis Spatholobi, Radix Rehmanniae Preparata, Radix Clematidis, Radix Paeoniae Alba, Radix Achyranthis Bidentatae are ground into coarse powder, concentrated, dry with 75% ethanol extract, again Zaocys, Scorpio, Scolopendra, Squama Manis (processed), Eupolyphaga Seu Steleophaga, Radix Aconiti Preparata, Semen Sinapis Albae are ground into 120 order fine powders after air-dry, be blended in 100 ℃ of following high temperature places 30 minutes with the said extracted thing, make powder and adorn 0.5 gram capsule.
Claims (6)
1, a kind of medicine for the treatment of intractable ischias pain, chronic lambago and skelalgia is characterized in that it is the medicament of being made by the following weight proportion raw material:
Zaocys 10-30 part Scorpio 5-15 part Scolopendra 1-10 part
Squama Manis (processed) 5-15 part Eupolyphaga Seu Steleophaga 5-15 part Radix Aconiti Preparata 1-10 part
Ramulus Cinnamomi 5-15 part Semen Sinapis Albae 10-30 part Radix Rehmanniae Preparata 15-50 part
Radix Paeoniae Alba 10-40 part Radix Polygoni Multiflori Preparata 15-50 part Caulis Spatholobi 15-50 part
Radix Achyranthis Bidentatae 10-25 part Radix Clematidis 5-15 part.
2, the medicine of treatment intractable ischias pain according to claim 1, chronic lambago and skelalgia, wherein the weight proportion of each raw material is:
Zaocys 15-20 part Scorpio 8-15 part Scolopendra 2-8 part
Squama Manis (processed) 8-12 part Eupolyphaga Seu Steleophaga 8-12 part Radix Aconiti Preparata 2-8 part
Ramulus Cinnamomi 8-15 part Semen Sinapis Albae 10-20 part Radix Rehmanniae Preparata 20-40 part
Radix Paeoniae Alba 15-30 part Radix Polygoni Multiflori Preparata 20-40 part Caulis Spatholobi 20-40 part
Radix Achyranthis Bidentatae 12-20 part Radix Clematidis 8-15 part.
3, the medicine of treatment intractable ischias pain according to claim 1, chronic lambago and skelalgia, wherein the weight proportion of each raw material is:
3 parts of 10 parts of Scolopendras of 20 portions of Scorpios of Zaocys
6 parts of 10 parts of Radix Aconiti Preparatas of 10 parts of Eupolyphaga Seu Steleophagas of Squama Manis (processed)
30 parts in 15 parts of Radix Rehmanniaes Preparata of 10 parts of Semen Sinapis Albaes of Ramulus Cinnamomi
30 parts of 30 portions of Caulis Spatholobis of 20 parts of Radix Polygoni Multiflori Preparatas of Radix Paeoniae Alba
10 parts of 15 parts of Radix Clematidis of Radix Achyranthis Bidentatae.
4, according to the medicine of claim 1,2 or 3 described treatment intractable ischias pains, chronic lambago and skelalgia, it is characterized in that said medicament is a said dosage form on any pharmaceutics.
5, the medicine of treatment intractable ischias pain according to claim 4, chronic lambago and skelalgia is characterized in that said medicament is a capsule.
6, the preparation method of the medicine of treatment intractable ischias pain according to claim 5, chronic lambago and skelalgia, it is characterized in that getting earlier Radix Clematidis, Ramulus Cinnamomi, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata, Caulis Spatholobi, Radix Achyranthis Bidentatae, Radix Paeoniae Alba pulverizing, extract with Diluted Alcohol solution, discard residue, after extracting solution concentrates, the residue drying; With Zaocys, Radix Aconiti Preparata, Eupolyphaga Seu Steleophaga, Squama Manis (processed), Scorpio, Scolopendra, the air-dry 120 order fine powders that are ground into of Semen Sinapis Albae, will mix with ethanol extraction after the above-mentioned powder drying, under 100-110 ℃ of temperature, carry out ripening, sterilization treatment 30 minutes makes capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00105845A CN1114420C (en) | 2000-04-11 | 2000-04-11 | Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00105845A CN1114420C (en) | 2000-04-11 | 2000-04-11 | Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1317321A CN1317321A (en) | 2001-10-17 |
| CN1114420C true CN1114420C (en) | 2003-07-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN00105845A Expired - Fee Related CN1114420C (en) | 2000-04-11 | 2000-04-11 | Medicine for treating intractable ischias and chronic lumbocrural pain and its preparing process |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104958575A (en) * | 2015-07-31 | 2015-10-07 | 佘延英 | Medicament for treating sciatica |
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| CN1317321A (en) | 2001-10-17 |
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