CN113116794A - Natural plant-based moisturizing composition and preparation method thereof - Google Patents
Natural plant-based moisturizing composition and preparation method thereof Download PDFInfo
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- CN113116794A CN113116794A CN202110255997.5A CN202110255997A CN113116794A CN 113116794 A CN113116794 A CN 113116794A CN 202110255997 A CN202110255997 A CN 202110255997A CN 113116794 A CN113116794 A CN 113116794A
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- moisturizing
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- 239000000203 mixture Substances 0.000 title claims abstract description 150
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 95
- 238000002360 preparation method Methods 0.000 title abstract description 18
- 239000003906 humectant Substances 0.000 claims abstract description 28
- 239000000419 plant extract Substances 0.000 claims abstract description 27
- 229940015975 1,2-hexanediol Drugs 0.000 claims abstract description 12
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 8
- 239000002904 solvent Substances 0.000 claims abstract description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 56
- 239000000284 extract Substances 0.000 claims description 46
- 241000196324 Embryophyta Species 0.000 claims description 43
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 39
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 35
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 26
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 26
- 235000011187 glycerol Nutrition 0.000 claims description 23
- 239000000047 product Substances 0.000 claims description 22
- 238000001816 cooling Methods 0.000 claims description 15
- 239000011265 semifinished product Substances 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 15
- 230000014759 maintenance of location Effects 0.000 claims description 14
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 13
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 13
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 13
- 229960000458 allantoin Drugs 0.000 claims description 13
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 13
- 239000004359 castor oil Substances 0.000 claims description 13
- 235000019438 castor oil Nutrition 0.000 claims description 13
- 229960001484 edetic acid Drugs 0.000 claims description 13
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 13
- 229960005323 phenoxyethanol Drugs 0.000 claims description 13
- 239000001509 sodium citrate Substances 0.000 claims description 13
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 13
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 10
- 239000004698 Polyethylene Substances 0.000 claims description 10
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- -1 polyethylene Polymers 0.000 claims description 10
- 229920000573 polyethylene Polymers 0.000 claims description 10
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 10
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 10
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims description 9
- 241000628997 Flos Species 0.000 claims description 7
- 150000001413 amino acids Chemical class 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 7
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 7
- 240000002129 Malva sylvestris Species 0.000 claims description 5
- 235000006770 Malva sylvestris Nutrition 0.000 claims description 5
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- 230000001804 emulsifying effect Effects 0.000 claims description 5
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- 230000001954 sterilising effect Effects 0.000 claims description 5
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims description 3
- 239000001140 aloe barbadensis leaf extract Substances 0.000 claims description 3
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- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- 239000004909 Moisturizer Substances 0.000 description 2
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- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
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- 235000006754 Taraxacum officinale Nutrition 0.000 description 2
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- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229940107681 dandelion root extract Drugs 0.000 description 2
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- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 241000195480 Fucus Species 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 108010003272 Hyaluronate lyase Proteins 0.000 description 1
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- 244000167230 Lonicera japonica Species 0.000 description 1
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- YKRGDOXKVOZESV-WRJNSLSBSA-N Paeoniflorin Chemical compound C([C@]12[C@H]3O[C@]4(O)C[C@](O3)([C@]1(C[C@@H]42)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)OC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-WRJNSLSBSA-N 0.000 description 1
- NEZONWMXZKDMKF-SNVBAGLBSA-N Shikonin Chemical compound C1=CC(O)=C2C(=O)C([C@H](O)CC=C(C)C)=CC(=O)C2=C1O NEZONWMXZKDMKF-SNVBAGLBSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
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- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
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- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 1
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 1
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 1
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- YKRGDOXKVOZESV-UHFFFAOYSA-N paeoniflorin Natural products O1C(C)(C2(CC34)OC5C(C(O)C(O)C(CO)O5)O)CC3(O)OC1C24COC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-UHFFFAOYSA-N 0.000 description 1
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- 239000000126 substance Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of moisturizing and moisturizing, and particularly relates to a natural plant-based moisturizing composition and a preparation method thereof. The invention provides a natural plant-based moisturizing composition and a preparation method thereof, aiming at the problems of poor moisturizing effect and short moisturizing time of moisturizing products in the prior art, wherein the natural plant-based moisturizing composition comprises a first composition, a second composition and a third composition which are uniformly mixed with each other, the first composition comprises a solvent, a moisturizing aid and a moisturizing agent, the second composition comprises 1, 2-hexanediol, and the third composition comprises a plant extract. The moisturizing auxiliary and the humectant are added, and the moisturizing auxiliary and the humectant are mutually cooperated, so that the composition has better moisturizing effect and moisturizing duration.
Description
Technical Field
The invention belongs to the technical field of moisturizing and moisturizing, and particularly relates to a natural plant-based moisturizing composition and a preparation method thereof.
Background
Moisture is one of important substances for human bodies to live and is also one of important components of the human bodies, and the life activities such as metabolism of the human bodies lacking moisture can be affected, for example, 10% of water loss of the human bodies threatens the health, and 20% of water loss of the human bodies can lead to death. The skin is one of the important organs of the human body, and the influence and the injury of the skin caused by water shortage are not negligible. The skin covered on the surface of a human body is affected most by external factors such as environment and the like, so that the skin is very easy to lose moisture, and the skin loses elasticity after being lack of water, and the repair and regeneration speed is reduced, so that the skin problems such as shrivelled, aged and poor in elasticity occur, and therefore the skin moisturizing repair becomes a theme of modern cosmetics. However, the moisturizing product in the prior art has poor moisturizing effect and short moisturizing time.
For example, the chinese invention patent application discloses a moisturizing and hydrating composition [ application No.: 201810129806.9], which patent application includes glycophosphorylcholine, carboxylated water-soluble chitosan, aqueous acrylate-polyurethane dispersions, glycolic acid, urethane, peregal O-25, silicone antifoam, trimethylglycine and purified water.
The invention has the advantages of having a large application range and well reducing the production cost of products, but the invention still does not solve the problems.
Disclosure of Invention
The invention aims to solve the problems and provides a natural plant-based moisturizing composition with good moisturizing effect.
In order to achieve the purpose, the invention adopts the following technical scheme:
a natural plant-based moisturizing composition comprises a first composition, a second composition and a third composition which are uniformly mixed with each other, wherein the first composition comprises a solvent, a moisturizing aid and a humectant, the second composition comprises 1, 2-hexanediol, and the third composition comprises a plant extract.
In the natural plant-based moisturizing composition, the first composition comprises, by mass, 44-93 parts of water, 0.01-0.1 part of ethylenediamine tetraacetic acid, 0.03-0.7 part of a moisturizing aid, 5-25 parts of a humectant, 2-10 parts of butanediol, 0.1-0.3 part of allantoin, 1-5 parts of bioglycasin, 0.001-0.1 part of citric acid, 0.001-0.1 part of sodium citrate and 0.2-0.5 part of p-hydroxyacetophenone.
In the natural plant-based moisturizing composition, the first composition comprises, by mass, 65 parts of water, 0.05 part of ethylenediamine tetraacetic acid, 0.4 part of a moisturizing aid, 15 parts of a moisturizing agent, 6 parts of butanediol, 0.2 part of allantoin, 3 parts of bioglycan, 0.05 part of citric acid, 0.05 part of sodium citrate, and 0.35 part of p-hydroxyacetophenone.
In the above-described natural plant-based moisturizing composition, the water in the first composition is glacier water.
In the natural plant-based moisturizing composition, the moisturizing aid comprises 0.01-0.1 part by weight of sodium polyacrylate, 0.01-0.5 part by weight of sodium hyaluronate and 0.01-0.1 part by weight of polyethylene glycol-90M.
In the natural plant-based moisturizing composition, the moisturizer comprises 2-10 parts by weight of glyceryl polyether-26, 2-10 parts by weight of glycerin and 1-5 parts by weight of amino acid moisturizer.
In the natural plant-based moisturizing composition, the third composition comprises, by mass, 0.01 to 0.1 part of PPG-26-butanol polyether-26, 0.01 to 0.1 part of PEG-40 hydrogenated castor oil, 0.01 to 0.1 part of water, 0.01 to 0.1 part of glycerin, 0.01 to 0.1 part of phenoxyethanol, 0.01 to 0.1 part of ethylhexyl glycerin and 0.1 to 2 parts of plant extracts.
In the natural plant-based moisturizing composition, the third composition comprises, by mass, 0.05 parts of PPG-26-butyether-26, 0.05 parts of PEG-40 hydrogenated castor oil, 0.05 parts of water, 0.05 parts of glycerin, 0.05 parts of phenoxyethanol, 0.05 parts of ethylhexyl glycerin and 1 part of plant extract.
In the above natural plant-based moisturizing composition, the plant extract includes one or more of an fucus extract, a chamomile flower extract, a malva sylvestris extract, a peony root extract, a honeysuckle flower extract, a dandelion root extract, a viola yedoensis extract, and an aloe barbadensis leaf extract.
The preparation method of the natural plant-based moisturizing composition comprises the following steps:
the method comprises the following steps: adding the first composition into an emulsifying pot, stirring, heating to 80-90 deg.C, sterilizing for 15-45 min;
step two: cooling to 55-65 deg.C, adding the second composition, and stirring;
step three: continuously cooling to 43-47 deg.C, adding the third composition, and stirring;
step four: continuously cooling to 38-42 ℃, discharging to obtain a semi-finished product;
step five: and step four, sampling and detecting the semi-finished product, and filling to obtain the finished product after the semi-finished product is detected to be qualified.
Compared with the prior art, the invention has the advantages that:
1. the moisturizing auxiliary and the humectant are added, and the moisturizing auxiliary and the humectant are mutually cooperated, so that the composition has better moisturizing effect and moisturizing duration.
2. The preparation method has the advantages of simple and reliable preparation process, convenient operation and lower production cost, and is suitable for large-scale popularization and application.
Detailed Description
The present invention will be described in further detail with reference to specific embodiments.
Example 1
This embodiment provides a natural plant-based moisturizing composition, including a first composition, a second composition, and a third composition, which are mixed with each other.
The first composition comprises, by mass, 44 parts of water, 0.1 part of ethylene diamine tetraacetic acid, 0.7 part of a moisturizing aid, 25 parts of a humectant, 10 parts of butanediol, 0.3 part of allantoin, 5 parts of bioglycan gum, 0.1 part of citric acid, 0.1 part of sodium citrate and 0.5 part of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.1 part by mass of sodium polyacrylate, 0.5 part by mass of sodium hyaluronate and 0.1 part by mass of polyethylene glycol-90M; the humectant comprises 10 parts of glyceryl polyether-26, 10 parts of glycerin and 5 parts of amino acid humectant.
The second composition included 0.5 parts 1, 2-hexanediol.
The third composition comprises 0.1 part by mass of PPG-26-butyether-26, 0.1 part by mass of PEG-40 hydrogenated castor oil, 0.1 part by mass of water, 0.1 part by mass of glycerol, 0.1 part by mass of phenoxyethanol, 0.1 part by mass of ethylhexyl glycerol and 2 parts by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract.
Bioglycan gum (CAS number: 194237-89-3), alias: fucoidan, fucoidan sulfate. Its molecule contains several sulfuric acid radicals, and has polyanion property and can stabilize emulsion system.
Polyethylene glycol-90M (CAS number: 25322-68-3), English name is PEG-90M, which has excellent lubricity, moisture retention, dispersibility and adhesiveness.
Fucus vesiculosus extract (CAS number: 84696-13-9) is derived from Fucus vesiculosus, and contains glutamic acid which can increase the softness and smoothness of skin, effectively nourish skin, provide sebum membrane for skin, protect skin, and help the metabolism of fat cells and the regeneration of connective tissue. The mineral, vitamin and polyphenol contained in the composition can stimulate the natural healing process of the body.
Example 2
This embodiment provides a natural plant-based moisturizing composition, including a first composition, a second composition, and a third composition, which are mixed with each other.
The first composition comprises 93 parts by mass of glacier water, 0.01 part by mass of ethylene diamine tetraacetic acid, 0.03 part by mass of a moisturizing aid, 5 parts by mass of a humectant, 2 parts by mass of butanediol, 0.1 part by mass of allantoin, 1 part by mass of biogel gum, 0.001 part by mass of citric acid, 0.001 part by mass of sodium citrate and 0.2 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.01 part by mass of sodium polyacrylate, 0.01 part by mass of sodium hyaluronate and 0.01 part by mass of polyethylene glycol-90M; the humectant comprises 2 parts of glyceryl polyether-26, 2 parts of glycerin and 1 part of amino acid humectant by mass.
The second composition included 0.2 parts 1, 2-hexanediol.
The third composition comprises 0.01 part by mass of PPG-26-butanol polyether-26, 0.01 part by mass of PEG-40 hydrogenated castor oil, 0.01 part by mass of water, 0.01 part by mass of glycerol, 0.01 part by mass of phenoxyethanol, 0.01 part by mass of ethylhexyl glycerol and 0.1 part by mass of plant extract. Wherein the plant extract comprises sea Oak (Fucus VESICULOSUS) extract, flos Matricariae Chamomillae (Chamomilla RECUTITA) extract, flos Malva sylvestris (MALVA SYLVESTRIS) extract, radix Paeoniae (Paeonia LACTIFLORA) root extract, flos Lonicerae (Lonicera JAPONICA) extract, herba Taraxaci (Taraxacum OFFICINALE) root extract, herba Violae (Viola YEDOENSIS) extract and Aloe Barbadensis (Aloe Barbadensis) leaf extract at equal mass ratio.
Flos Matricariae Chamomillae extract, i.e. flos Matricariae Chamomillae extract. Has effects of balancing oil secretion, inhibiting fat, resisting acne, preventing acne, eliminating black speck, and whitening skin. Commercially available products such as chamomile extract produced by walteris biotechnology limited, lanzhou, may be used.
The malva sylvestris extract (CAS number: 84082-57-5) can relieve dry skin, form water-locking film on skin surface, and enhance skin defense function.
Radix Paeoniae extract (CAS number: 84929-40-8) contains paeoniflorin as effective component, and has inhibitory effect on certain pathogenic bacteria and fungi. The peony extract has the functions of activating skin and resisting aging, and can be used for anti-aging cosmetics. And has better moisture retention capability.
The honeysuckle flower extract is honeysuckle flower extract, contains caffeotannic acid, and has strong antibacterial, fat reducing, skin caring and skin aging preventing effects. The luteolin has antibacterial and antiinflammatory effects, has strong skin penetration, can reach deep skin, and can inhibit hyaluronidase activity, prolong the activity of the product, eliminate free radicals, and absorb ultraviolet, so as to inhibit and eliminate skin color spot, especially senile plaque. Commercially available products such as honeysuckle flower extract produced by Gansu Probiotics Biotech limited may be used.
Taraxacum officinale root extract (CAS number: 84775-55-3), which is extracted from Taraxacum officinale root and stem, has antiinflammatory, antibacterial and skin conditioning effects, can dilate blood vessel at high concentration, and can be used in skin cream, astringent and astringent products and hair care products.
The herba Violae extract and herba Violae extract have antagonistic effect on endotoxin. Commercially available products such as Tokyo violet herb extract produced by Yishan intermediates Ltd in Ruicheng county can be used.
Aloe barbadensis leaf extract (CAS number: 94349-62-9) has various biological activities, and is an important additive component in cosmetics. The promotion effect on the growth of fibrin, the inhibition of elastin, the synthesis of collagen and the elimination effect on free radicals show that the skin-activating and anti-aging effects are good; has effects in promoting cholesterol synthesis, changing sebum composition, reducing gloss, and improving skin softness; it also has antibacterial, antiinflammatory and moisture keeping effects.
Example 3
This embodiment provides a natural plant-based moisturizing composition, including a first composition, a second composition, and a third composition, which are mixed with each other.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.4 part by mass of a moisturizing aid, 15 parts by mass of a moisturizing agent, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of bioglycan gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.05 part by mass of sodium polyacrylate, 0.3 part by mass of sodium hyaluronate and 0.05 part by mass of polyethylene glycol-90M; the humectant comprises 6 parts by weight of glyceryl polyether-26, 6 parts by weight of glycerin and 3 parts by weight of amino acid humectant.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Example 4
The embodiment provides a preparation method of a natural plant-based moisturizing composition, which comprises the following steps:
the method comprises the following steps: adding the first composition into an emulsifying pot, stirring, heating to 80 deg.C, and sterilizing for 15 min;
step two: cooling to 55 deg.C, adding the second composition, and stirring;
step three: continuously cooling to 43 ℃, adding the third composition, and uniformly stirring;
step four: continuously cooling to 38 ℃, and discharging to obtain a semi-finished product;
step five: and step four, sampling and detecting the semi-finished product, and filling to obtain the finished product after the semi-finished product is detected to be qualified.
Example 5
The embodiment provides a preparation method of a natural plant-based moisturizing composition, which comprises the following steps:
the method comprises the following steps: adding the first composition into an emulsifying pot, stirring, heating to 90 deg.C, and sterilizing for 45 min;
step two: cooling to 65 ℃, adding the second composition, and uniformly stirring;
step three: continuously cooling to 47 ℃, adding the third composition, and uniformly stirring;
step four: continuously cooling to 42 ℃, discharging to obtain a semi-finished product;
step five: and step four, sampling and detecting the semi-finished product, and filling to obtain the finished product after the semi-finished product is detected to be qualified.
Example 6
The embodiment provides a preparation method of a natural plant-based moisturizing composition, which comprises the following steps:
the method comprises the following steps: adding the first composition into an emulsifying pot, stirring, heating to 85 deg.C, and sterilizing for 30 min;
step two: cooling to 60 deg.C, adding the second composition, and stirring;
step three: continuously cooling to 45 ℃, adding the third composition, and uniformly stirring;
step four: continuously cooling to 40 ℃, and discharging to obtain a semi-finished product;
step five: and step four, sampling and detecting the semi-finished product, and filling to obtain the finished product after the semi-finished product is detected to be qualified.
Comparative example 1
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.05 part by mass of a moisturizing aid, 3 parts by mass of a humectant, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of biogel gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.05 part by mass of polyethylene glycol-90M; the humectant comprises 3 parts by mass of amino acid humectant.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Comparative example 2
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.35 part by mass of a moisturizing aid, 6 parts by mass of a humectant, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of biogel gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.05 part of sodium polyacrylate and 0.3 part of sodium hyaluronate in parts by mass; the humectant comprises 6 parts by mass of glycerin.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Comparative example 3
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.3 part by mass of a moisturizing aid, 12 parts by mass of a moisturizing agent, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of bioglycan gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.3 part by mass of sodium hyaluronate; the humectant comprises 6 parts by weight of glyceryl polyether-26 and 6 parts by weight of glycerin.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Comparative example 4
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.35 part by mass of a moisturizing aid, 12 parts by mass of a moisturizing agent, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of bioglycan gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.3 part of sodium hyaluronate and 0.05 part of polyethylene glycol-90M in parts by mass; the humectant comprises 6 parts by weight of glyceryl polyether-26 and 6 parts by weight of glycerin.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Comparative example 5
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.4 part by mass of a moisturizing aid, 12 parts by mass of a moisturizing agent, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of bioglycan gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.05 part by mass of sodium polyacrylate, 0.3 part by mass of sodium hyaluronate and 0.05 part by mass of polyethylene glycol-90M; the humectant comprises 6 parts by weight of glyceryl polyether-26 and 6 parts by weight of glycerin.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Comparative example 6
The comparative example provides a natural plant-based moisturizing composition comprising a first composition, a second composition, and a third composition mixed uniformly with one another.
The first composition comprises 65 parts by mass of glacier water, 0.05 part by mass of ethylene diamine tetraacetic acid, 0.35 part by mass of a moisturizing aid, 15 parts by mass of a moisturizing agent, 6 parts by mass of butanediol, 0.2 part by mass of allantoin, 3 parts by mass of bioglycan gum, 0.05 part by mass of citric acid, 0.05 part by mass of sodium citrate and 0.35 part by mass of p-hydroxyacetophenone. Wherein the moisture retention aid comprises 0.3 part of sodium hyaluronate and 0.05 part of polyethylene glycol-90M in parts by mass; the humectant comprises 6 parts by weight of glyceryl polyether-26, 6 parts by weight of glycerin and 3 parts by weight of amino acid humectant.
The second composition included 0.35 parts 1, 2-hexanediol.
The third composition comprises 0.05 part by mass of PPG-26-butynol polyether-26, 0.05 part by mass of PEG-40 hydrogenated castor oil, 0.05 part by mass of water, 0.05 part by mass of glycerol, 0.05 part by mass of phenoxyethanol, 0.05 part by mass of ethylhexyl glycerol and 1 part by mass of plant extract. Wherein the plant extract comprises Fucus VESICULOSUS (Fucus VESICULOSUS) extract and Matricaria CHAMOMILLA (Chamomilla RECUTITA) flower extract at equal mass ratio.
Application example 1
Preparing a skin care product 1 by the preparation method described in example 6 according to the component ratio of the natural plant-based moisturizing composition described in example 3;
preparing a skin care product 2 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 1;
preparing a skin care product 3 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 2;
preparing a skin care product 4 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 3;
preparing a skin care product 5 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 4;
preparing a skin care product 6 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 5;
preparing a skin care product 7 by the preparation method described in the example 6 according to the component ratio of the natural plant-based moisturizing composition described in the comparative example 6;
randomly selecting 28 volunteers with the age of 18-65 years, randomly dividing the volunteers into 7 groups, namely 1-7 experimental groups, respectively smearing skin care products 1-7 on 4 persons in each group and 1-7 volunteers in the experimental groups, measuring the skin surface humidity of the volunteers by using a method recorded in QB/T4256-:
moisture retention rate-skin humidity in experimental area-skin humidity in contrast area
The moisture retention rate of each person is calculated, the average value is calculated in the experimental group, and the skin care product is applied for 1h, 2h and 3h and then tested once respectively, and the results are shown in the following table:
and (4) analyzing results: as can be seen from the table above, the natural plant-based moisturizing composition provided by the invention has good moisturizing effect and long moisturizing time, and achieves the expected purpose of the invention.
The specific embodiments described herein are merely illustrative of the spirit of the invention. Various modifications or additions may be made to the described embodiments or alternatives may be employed by those skilled in the art without departing from the spirit or ambit of the invention as defined in the appended claims.
Claims (10)
1. A natural plant-based moisturizing composition is characterized in that: the composition comprises a first composition, a second composition and a third composition which are uniformly mixed with each other, wherein the first composition comprises a solvent, a moisturizing aid and a humectant, the second composition comprises 1, 2-hexanediol, and the third composition comprises a plant extract.
2. The natural plant-based moisturizing composition of claim 1, wherein: the first composition comprises, by mass, 44-93 parts of water, 0.01-0.1 part of ethylene diamine tetraacetic acid, 0.03-0.7 part of a moisturizing aid, 5-25 parts of a humectant, 2-10 parts of butanediol, 0.1-0.3 part of allantoin, 1-5 parts of bioglycan gum, 0.001-0.1 part of citric acid, 0.001-0.1 part of sodium citrate and 0.2-0.5 part of p-hydroxyacetophenone.
3. The natural plant-based moisturizing composition of claim 2, wherein: the first composition comprises, by mass, 65 parts of water, 0.05 part of ethylene diamine tetraacetic acid, 0.4 part of a moisturizing aid, 15 parts of a moisturizing agent, 6 parts of butanediol, 0.2 part of allantoin, 3 parts of bioglycan gum, 0.05 part of citric acid, 0.05 part of sodium citrate and 0.35 part of p-hydroxyacetophenone.
4. The natural plant-based moisturizing composition of claim 2, wherein: the water in the first composition is glacier water.
5. The natural plant-based moisturizing composition of claim 2, wherein: the moisture retention aid comprises 0.01-0.1 part of sodium polyacrylate, 0.01-0.5 part of sodium hyaluronate and 0.01-0.1 part of polyethylene glycol-90M in parts by mass.
6. The natural plant-based moisturizing composition of claim 2, wherein: the humectant comprises 2-10 parts by weight of glyceryl polyether-26, 2-10 parts by weight of glycerin and 1-5 parts by weight of amino acid humectant.
7. The natural plant-based moisturizing composition of claim 1, wherein: the third composition comprises 0.01-0.1 part by mass of PPG-26-butanol polyether-26, 0.01-0.1 part by mass of PEG-40 hydrogenated castor oil, 0.01-0.1 part by mass of water, 0.01-0.1 part by mass of glycerol, 0.01-0.1 part by mass of phenoxyethanol, 0.01-0.1 part by mass of ethylhexyl glycerol and 0.1-2 parts by mass of plant extract.
8. The natural plant-based moisturizing composition of claim 7, wherein: the third composition comprises, by mass, 0.05 part of PPG-26-butynol polyether-26, 0.05 part of PEG-40 hydrogenated castor oil, 0.05 part of water, 0.05 part of glycerin, 0.05 part of phenoxyethanol, 0.05 part of ethylhexyl glycerin and 1 part of plant extract.
9. The natural plant-based moisturizing composition of claim 7, wherein: the plant extract comprises one or more of Fucus vesiculosus extract, flos Matricariae Chamomillae extract, Malva sylvestris extract, radix Paeoniae extract, flos Lonicerae extract, herba Taraxaci root extract, herba Violae extract and Aloe Barbadensis leaf extract.
10. A method of preparing the natural plant based moisturizing composition of any of claims 1-9, comprising the steps of:
the method comprises the following steps: adding the first composition into an emulsifying pot, stirring, heating to 80-90 deg.C, sterilizing for 15-45 min;
step two: cooling to 55-65 deg.C, adding the second composition, and stirring;
step three: continuously cooling to 43-47 deg.C, adding the third composition, and stirring;
step four: continuously cooling to 38-42 ℃, discharging to obtain a semi-finished product;
step five: and step four, sampling and detecting the semi-finished product, and filling to obtain the finished product after the semi-finished product is detected to be qualified.
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CN108969433A (en) * | 2018-07-12 | 2018-12-11 | 广州皓雨投资有限公司 | Double-colored facial treatment mask and preparation method thereof with whitening, moisturizing and Shu Min effect |
CN109106664A (en) * | 2018-08-13 | 2019-01-01 | 广州皓雨投资有限公司 | Have effects that moisturizing is releived the composition of maintenance, facial mask and preparation method thereof |
CN109431928A (en) * | 2018-11-19 | 2019-03-08 | 广州市皓雨化妆品有限公司 | It is a kind of with moisturizing, releive, the composition of white-skinned face function and application |
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2021
- 2021-03-09 CN CN202110255997.5A patent/CN113116794A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108969433A (en) * | 2018-07-12 | 2018-12-11 | 广州皓雨投资有限公司 | Double-colored facial treatment mask and preparation method thereof with whitening, moisturizing and Shu Min effect |
CN109106664A (en) * | 2018-08-13 | 2019-01-01 | 广州皓雨投资有限公司 | Have effects that moisturizing is releived the composition of maintenance, facial mask and preparation method thereof |
CN109431928A (en) * | 2018-11-19 | 2019-03-08 | 广州市皓雨化妆品有限公司 | It is a kind of with moisturizing, releive, the composition of white-skinned face function and application |
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Title |
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上海诺薇兰日化有限公司: "诺薇兰冰之密柔柔水(滋润型)", 《国产普通化妆品备案信息》 * |
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