CN1130871A - 用取代的氮杂螺烷抑制人体免疫缺陷病毒的复制的方法 - Google Patents

用取代的氮杂螺烷抑制人体免疫缺陷病毒的复制的方法 Download PDF

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Publication number
CN1130871A
CN1130871A CN94193381A CN94193381A CN1130871A CN 1130871 A CN1130871 A CN 1130871A CN 94193381 A CN94193381 A CN 94193381A CN 94193381 A CN94193381 A CN 94193381A CN 1130871 A CN1130871 A CN 1130871A
Authority
CN
China
Prior art keywords
chemical compound
hiv
formula
solvate
hydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94193381A
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English (en)
Chinese (zh)
Inventor
A·M·贝杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of CN1130871A publication Critical patent/CN1130871A/zh
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN94193381A 1993-07-23 1994-07-22 用取代的氮杂螺烷抑制人体免疫缺陷病毒的复制的方法 Pending CN1130871A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939315340A GB9315340D0 (en) 1993-07-23 1993-07-23 Methods
GB9315340.1 1993-07-23

Publications (1)

Publication Number Publication Date
CN1130871A true CN1130871A (zh) 1996-09-11

Family

ID=10739357

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94193381A Pending CN1130871A (zh) 1993-07-23 1994-07-22 用取代的氮杂螺烷抑制人体免疫缺陷病毒的复制的方法

Country Status (9)

Country Link
EP (1) EP0711160A4 (ja)
JP (1) JPH09500648A (ja)
CN (1) CN1130871A (ja)
AU (1) AU7370994A (ja)
CA (1) CA2167842A1 (ja)
GB (1) GB9315340D0 (ja)
NZ (1) NZ269991A (ja)
WO (1) WO1995003042A1 (ja)
ZA (1) ZA945418B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315351D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
BR9601909A (pt) * 1995-07-13 1999-10-13 Smithkline Beecham Corp N,n-dietil-8,8-dipropil-2-azaspiro(4,5)decano-2-propan amina dimaleato
WO1997044030A1 (en) * 1996-05-17 1997-11-27 Anormed Inc. Use of substituted azaspirane in the treatment of asthma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
ZA921120B (en) * 1991-02-19 1993-01-27 Smithkline Beecham Corp Cytokine inhibitors
GB9201803D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Corp Methods
GB9201804D0 (en) * 1992-01-28 1992-03-11 Smithkline Beecham Corp Methods
GB9315298D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315351D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods
GB9315306D0 (en) * 1993-07-23 1993-09-08 Smithkline Beecham Corp Methods

Also Published As

Publication number Publication date
EP0711160A4 (en) 1998-09-09
ZA945418B (en) 1995-05-10
GB9315340D0 (en) 1993-09-08
JPH09500648A (ja) 1997-01-21
EP0711160A1 (en) 1996-05-15
AU7370994A (en) 1995-02-20
WO1995003042A1 (en) 1995-02-02
CA2167842A1 (en) 1995-02-02
NZ269991A (en) 1999-07-29

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication