CN113082165A - 一种辅助降三高的组合物及其制备方法和应用 - Google Patents
一种辅助降三高的组合物及其制备方法和应用 Download PDFInfo
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Abstract
本发明公开的属于保健食品技术领域，具体为一种辅助降三高的组合物及其制备方法和应用，该组合物由如下重量数的原料组成：菊苣、栀子、葛根、蒲公英、山楂、桑葚提取物、苦瓜提取物、陈皮、菊花、连翘、茯苓、白术、猕猴桃提取物、菠萝提取物、石斛提取物，本发明原料易得，价格便宜，制备工艺简单，与市面上的中西医药物相比，不具有毒副作用，降三高效果显著，对人体能够进行食补的效果，人体不会对组合物产生依赖性，随着服药时间的增加，药效不会产生减退的情况，能够改善人体的机能，同时起到了调理身体的作用。
Description
技术领域
本发明涉及保健食品技术领域，具体为一种辅助降三高的组合物及其制备方法和应用。
背景技术
“三高症”是指高血压、高血糖(糖尿病)和高脂血症。是现代社会所派生出来的“富贵病”，可能单独存在，也可能相互关联。由于长时间饮食习惯问题，饮食中脂类过多，醇类过多。同时又没有合理的运动促进脂类醇类的代谢，导致体内脂类醇类物质逐渐增多，掺杂在血液中，使毛细血管堵塞，随着时间的推移，脂类醇类物质容易和体内游离的矿物质离子结合，形成血栓。血栓容易在血管的拐角处，或者瓶颈处堆积，钙化。同时血栓越来越多，使血管直径缩小。心脏为了保持足够的供血量，就增加血压，造成高血压疾病。血脂主要是指血清中的胆固醇和甘油三酯。无论是胆固醇含量增高，还是甘油三脂的含量增高，或是两者皆增高，统称为高脂血症。高血脂可以引起血管栓塞；高血压可以引起脑出血和脑血管破裂；高血糖可以引起糖尿病。目前三高人群数量在不断增加。
现有的治疗方法主要是依靠中西医药物，辅助饮食控制和运动进行治疗，但现有的中西医药物具有一定的副作用，人体会对药物产生一定的依赖性，随着服药时间的增加，药效会不断的减退。
发明内容
本发明的目的在于提供一种辅助降三高的组合物及其制备方法和应用，以解决上述背景技术中提出的具有一定的副作用，药效会不断的减退的问题。
为实现上述目的，本发明提供如下技术方案：一种辅助降三高的组合物，该组合物由如下重量份数的原料组成：菊苣6-10份、栀子8-10份、葛根6-8份、蒲公英6-8份、山楂6-10份、桑葚提取物6-10份、苦瓜提取物6-8份、陈皮4-8份、菊花4-6份、连翘4-8份、茯苓6-10份、白术6-8份、猕猴桃提取物4-6份、菠萝提取物4-8份、石斛提取物2-6份。
优选的，该组合物由如下重量份数的原料组成：菊苣6份、栀子8份、葛根6份、蒲公英6份、山楂6份、桑葚提取物6份、苦瓜提取物6份、陈皮4份、菊花4份、连翘4份、茯苓6份、白术6份、猕猴桃提取物4份、菠萝提取物4份、石斛提取物2份。
优选的，该组合物由如下重量份数的原料组成：菊苣8份、栀子9份、葛根7份、蒲公英7份、山楂7份、桑葚提取物8份、苦瓜提取物7份、陈皮6份、菊花5份、连翘6份、茯苓9份、白术7份、猕猴桃提取物5份、菠萝提取物7份、石斛提取物4份。
优选的，该组合物由如下重量份数的原料组成：菊苣10份、栀子10份、葛根8份、蒲公英8份、山楂10份、桑葚提取物10份、苦瓜提取物8份、陈皮8份、菊花6份、连翘8份、茯苓10份、白术8份、猕猴桃提取物6份、菠萝提取物8份、石斛提取物6份。
优选的，所述组合物包括药片、粉剂、颗粒剂、胶囊、片剂中的一种或多种。
该组合物的制备方法包括以下步骤：
步骤1：提取物的制备，取桑葚、苦瓜、猕猴桃、菠萝与石斛的原料，粉碎分别后放入不同的提取罐中，向每个提取罐中加入5倍的蒸馏水回流提取2次，合并提取液后过滤，滤液减压浓缩，浓缩液加入乙醇醇沉，使含乙醇量为60％-70％，静置后离心，取上清液浓缩，经喷雾干燥分别得到桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物；
步骤2：提取处理，将菊苣、栀子、葛根、蒲公英、山楂、陈皮、菊花、连翘、茯苓与白术放入真空提取罐中，将提取罐中的空气抽出，使得真空提取罐中保持负压，并向真空提取罐中加入60-80℃的蒸馏水，浸泡30-40min后将药液与药物取出进行固液分离，将药物进行粉碎后加入药液中，对药液进行加热至100-120℃，煎煮20-30min后，冷却后对混合液进行浓缩，获得浓缩液；
步骤3：混合处理，将步骤1中的桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物加入步骤2中的浓缩液中，并搅拌均匀，经过干燥后得到混合粉；
步骤4：成形处理，对混合粉进行加工成形，并根据需求进行包装。
与现有技术相比，本发明的有益效果是：
1)本发明原料易得，价格便宜，制备工艺简单，与市面上的中西医药物相比，不具有毒副作用，降三高效果显著，对人体能够进行食补的效果，人体不会对组合物产生依赖性。
2)本发明随着服药时间的增加，药效不会产生减退的情况，能够改善人体的机能，同时起到了调理身体的作用。
附图说明
图1为本发明流程示意图。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
在本发明的描述中，需要理解的是，术语“上”、“下”、“前”、“后”、“左”、“右”、“顶”、“底”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。
请参阅图1，本发明提供一种技术方案：
实施例1：
一种辅助降三高的组合物，该组合物由如下重量份数的原料组成：菊苣6份、栀子8份、葛根6份、蒲公英6份、山楂6份、桑葚提取物6份、苦瓜提取物6份、陈皮4份、菊花4份、连翘4份、茯苓6份、白术6份、猕猴桃提取物4份、菠萝提取物4份、石斛提取物2份。
所述组合物包括药片、粉剂、颗粒剂、胶囊、片剂中的一种或多种。
该组合物的制备方法包括以下步骤：
步骤1：提取物的制备，取桑葚、苦瓜、猕猴桃、菠萝与石斛的原料，粉碎分别后放入不同的提取罐中，向每个提取罐中加入5倍的蒸馏水回流提取2次，合并提取液后过滤，滤液减压浓缩，浓缩液加入乙醇醇沉，使含乙醇量为60％-70％，静置后离心，取上清液浓缩，经喷雾干燥分别得到桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物；
步骤2：提取处理，将菊苣、栀子、葛根、蒲公英、山楂、陈皮、菊花、连翘、茯苓与白术放入真空提取罐中，将提取罐中的空气抽出，使得真空提取罐中保持负压，并向真空提取罐中加入60-80℃的蒸馏水，浸泡30-40min后将药液与药物取出进行固液分离，将药物进行粉碎后加入药液中，对药液进行加热至100-120℃，煎煮20-30min后，冷却后对混合液进行浓缩，获得浓缩液；
步骤3：混合处理，将步骤1中的桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物加入步骤2中的浓缩液中，并搅拌均匀，经过干燥后得到混合粉；
步骤4：成形处理，对混合粉进行加工成形，并根据需求进行包装。
实施例2：
一种辅助降三高的组合物，该组合物由如下重量份数的原料组成：菊苣8份、栀子9份、葛根7份、蒲公英7份、山楂7份、桑葚提取物8份、苦瓜提取物7份、陈皮6份、菊花5份、连翘6份、茯苓9份、白术7份、猕猴桃提取物5份、菠萝提取物7份、石斛提取物4份。
所述组合物包括药片、粉剂、颗粒剂、胶囊、片剂中的一种或多种。
该组合物的制备方法包括以下步骤：
步骤1：提取物的制备，取桑葚、苦瓜、猕猴桃、菠萝与石斛的原料，粉碎分别后放入不同的提取罐中，向每个提取罐中加入5倍的蒸馏水回流提取2次，合并提取液后过滤，滤液减压浓缩，浓缩液加入乙醇醇沉，使含乙醇量为60％-70％，静置后离心，取上清液浓缩，经喷雾干燥分别得到桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物；
步骤2：提取处理，将菊苣、栀子、葛根、蒲公英、山楂、陈皮、菊花、连翘、茯苓与白术放入真空提取罐中，将提取罐中的空气抽出，使得真空提取罐中保持负压，并向真空提取罐中加入60-80℃的蒸馏水，浸泡30-40min后将药液与药物取出进行固液分离，将药物进行粉碎后加入药液中，对药液进行加热至100-120℃，煎煮20-30min后，冷却后对混合液进行浓缩，获得浓缩液；
步骤3：混合处理，将步骤1中的桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物加入步骤2中的浓缩液中，并搅拌均匀，经过干燥后得到混合粉；
步骤4：成形处理，对混合粉进行加工成形，并根据需求进行包装。
实施例3：
一种辅助降三高的组合物，该组合物由如下重量份数的原料组成：菊苣10份、栀子10份、葛根8份、蒲公英8份、山楂10份、桑葚提取物10份、苦瓜提取物8份、陈皮8份、菊花6份、连翘8份、茯苓10份、白术8份、猕猴桃提取物6份、菠萝提取物8份、石斛提取物6份。
所述组合物包括药片、粉剂、颗粒剂、胶囊、片剂中的一种或多种。
该组合物的制备方法包括以下步骤：
步骤1：提取物的制备，取桑葚、苦瓜、猕猴桃、菠萝与石斛的原料，粉碎分别后放入不同的提取罐中，向每个提取罐中加入5倍的蒸馏水回流提取2次，合并提取液后过滤，滤液减压浓缩，浓缩液加入乙醇醇沉，使含乙醇量为60％-70％，静置后离心，取上清液浓缩，经喷雾干燥分别得到桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物；
步骤2：提取处理，将菊苣、栀子、葛根、蒲公英、山楂、陈皮、菊花、连翘、茯苓与白术放入真空提取罐中，将提取罐中的空气抽出，使得真空提取罐中保持负压，并向真空提取罐中加入60-80℃的蒸馏水，浸泡30-40min后将药液与药物取出进行固液分离，将药物进行粉碎后加入药液中，对药液进行加热至100-120℃，煎煮20-30min后，冷却后对混合液进行浓缩，获得浓缩液；
步骤3：混合处理，将步骤1中的桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物加入步骤2中的浓缩液中，并搅拌均匀，经过干燥后得到混合粉；
步骤4：成形处理，对混合粉进行加工成形，并根据需求进行包装。
选择了5位三高的患者，并使用本发明实施例1-实施例3制备得到的组合物3周后，对分别对五位患者的血压、血脂与血糖进行检测，均在正常值范围，因此本发明降三高效果显著。
以上显示和描述了本发明的基本原理和主要特征和本发明的优点,对于本领域技术人员而言，显然本发明不限于上述示范性实施例的细节，而且在不背离本发明的精神或基本特征的情况下，能够以其他的具体形式实现本发明；因此，无论从哪一点来看，均应将实施例看作是示范性的，而且是非限制性的，本发明的范围由所附权利要求而不是上述说明限定，因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内，不应将权利要求中的任何附图标记视为限制所涉及的权利要求。
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限定。
Claims (7)
1.一种辅助降三高的组合物，其特征在于：该组合物由如下重量份数的原料组成：菊苣6-10份、栀子8-10份、葛根6-8份、蒲公英6-8份、山楂6-10份、桑葚提取物6-10份、苦瓜提取物6-8份、陈皮4-8份、菊花4-6份、连翘4-8份、茯苓6-10份、白术6-8份、猕猴桃提取物4-6份、菠萝提取物4-8份、石斛提取物2-6份。
2.根据权利要求1所述的一种辅助降三高的组合物，其特征在于：该组合物由如下重量份数的原料组成：菊苣6份、栀子8份、葛根6份、蒲公英6份、山楂6份、桑葚提取物6份、苦瓜提取物6份、陈皮4份、菊花4份、连翘4份、茯苓6份、白术6份、猕猴桃提取物4份、菠萝提取物4份、石斛提取物2份。
3.根据权利要求1所述的一种辅助降三高的组合物，其特征在于：该组合物由如下重量份数的原料组成：菊苣8份、栀子9份、葛根7份、蒲公英7份、山楂7份、桑葚提取物8份、苦瓜提取物7份、陈皮6份、菊花5份、连翘6份、茯苓9份、白术7份、猕猴桃提取物5份、菠萝提取物7份、石斛提取物4份。
4.根据权利要求1所述的一种辅助降三高的组合物，其特征在于：该组合物由如下重量份数的原料组成：菊苣10份、栀子10份、葛根8份、蒲公英8份、山楂10份、桑葚提取物10份、苦瓜提取物8份、陈皮8份、菊花6份、连翘8份、茯苓10份、白术8份、猕猴桃提取物6份、菠萝提取物8份、石斛提取物6份。
5.根据权利要求1所述的一种辅助降三高的组合物，其特征在于：所述组合物包括药片、粉剂、颗粒剂、胶囊、片剂中的一种或多种。
6.根据权利要求1-5任一项所述的一种辅助降三高的组合物，其特征在于：该组合物的制备方法包括以下步骤：
步骤1：提取物的制备，取桑葚、苦瓜、猕猴桃、菠萝与石斛的原料，粉碎分别后放入不同的提取罐中，向每个提取罐中加入5倍的蒸馏水回流提取2次，合并提取液后过滤，滤液减压浓缩，浓缩液加入乙醇醇沉，使含乙醇量为60％-70％，静置后离心，取上清液浓缩，经喷雾干燥分别得到桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物；
步骤2：提取处理，将菊苣、栀子、葛根、蒲公英、山楂、陈皮、菊花、连翘、茯苓与白术放入真空提取罐中，将提取罐中的空气抽出，使得真空提取罐中保持负压，并向真空提取罐中加入60-80℃的蒸馏水，浸泡30-40min后将药液与药物取出进行固液分离，将药物进行粉碎后加入药液中，对药液进行加热至100-120℃，煎煮20-30min后，冷却后对混合液进行浓缩，获得浓缩液；
步骤3：混合处理，将步骤1中的桑葚提取物、苦瓜提取物、猕猴桃提取物、菠萝提取物与石斛提取物加入步骤2中的浓缩液中，并搅拌均匀，经过干燥后得到混合粉；
步骤4：成形处理，对混合粉进行加工成形，并根据需求进行包装。
7.根据权利要求1-5任一项所述的组合物在降高血压、降高血糖、降高血脂药物中的应用。
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