CN112972345A - Anti-inflammatory herbal shower gel - Google Patents

Anti-inflammatory herbal shower gel Download PDF

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Publication number
CN112972345A
CN112972345A CN201911295260.5A CN201911295260A CN112972345A CN 112972345 A CN112972345 A CN 112972345A CN 201911295260 A CN201911295260 A CN 201911295260A CN 112972345 A CN112972345 A CN 112972345A
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shower gel
parts
weight
mixing
chinese medicine
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Inventor
张梦福
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Guizhou Qiaosheng Biotechnology Co ltd
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Guizhou Qiaosheng Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention belongs to the field of daily chemicals, and particularly relates to anti-inflammatory herbal shower gel. The composition is characterized by comprising the following raw materials in parts by weight: 0.1-5% of herbal extract, 30-60% of surfactant, 1-10% of humectant, 0.1-3% of thickener, 0.01-1% of chelating agent, 0.1-5% of excipient, 0.01-0.1% of preservative, 0.001-0.01% of essence and the balance of deionized water. The shower gel provided by the invention has the effects of bacteriostasis, anti-inflammation and moistening, can effectively avoid seborrheic dermatitis after being used for a long time, and moistens dry skin; the dendrobium officinale, the grassleaf sweelflag rhizome, the parasitic loranthus and the semiliquidambar cathayensis are common medicinal materials in river regions, and the research of the invention can promote the development of local traditional Chinese medicine industry.

Description

Anti-inflammatory herbal shower gel
Technical Field
The invention belongs to the field of daily chemicals, and particularly relates to anti-inflammatory herbal shower gel.
Background
Seborrheic dermatitis is better developed in the parts with more sebaceous glands, such as scalp, face, back, axillary part, perineum, etc., and severe seborrheic dermatitis can be generalized to the whole body. The main symptoms are slight yellowish erythema on the skin, accompanied by fine and smooth fresh crumbs and scabs, and itching feeling of the skin. People suffering from seborrheic dermatitis are sensitive to cold and hot alternation, particularly, the face is easy to be reddened, scalded and itchy, and the phenomenon of redness and swelling can be caused seriously, so that the seborrheic dermatitis is easy to cause.
Besides applying ointment, the bath cream can be started from the bath cream used by people in daily life, and the patent number CN201810547925.6 comprises the following components: the bath lotion is reasonable in formula, stable in foam, easy to wash, mild in performance, capable of effectively absorbing moisture in air, good in sterilization and bacteriostasis effects, capable of effectively relieving dryness and tightness of skin, effectively inhibiting pruritus, nourishing and moistening skin and adjusting pH value, capable of making skin tender after long-term use, capable of sterilizing, inhibiting bacteria, diminishing inflammation and relieving itching, capable of protecting grease on the surface layer of the skin, and simple in preparation method and low in cost. However, the production process is easy to cause the problems of poor product stability and uncontrollable quality. Therefore, the shower gel provided by the invention has good antibacterial, anti-inflammatory and moisturizing effects and stable quality.
Disclosure of Invention
The invention provides anti-inflammatory herbal shower gel for solving the technical problems.
The method is realized by the following technical scheme:
the anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 0.1-5% of herbal extract, 30-60% of surfactant, 1-10% of humectant, 0.1-3% of thickener, 0.01-1% of chelating agent, 0.1-5% of excipient, 0.01-0.1% of preservative, 0.001-0.01% of essence and the balance of deionized water.
The herbal extract is prepared by grinding 3-6 parts of dendrobium officinale, 3-6 parts of rhizoma acori graminei, 2-5 parts of loranthus parasiticus and 2-5 parts of semiliquidambar cathayensis by weight, sieving with a 20-30-mesh sieve, adding 40-50% ethanol solution which is 20-30 times of the total herbal mass, performing reflux extraction for 2 times, each time for 1-2 hours, filtering, and volatilizing ethanol.
The surfactant is: one or more of sodium cocoyl glycinate, sodium laureth sulfate and cocamidopropyl betaine;
the humectant is one or more of glycerol, butanediol, allantoin and sodium hyaluronate;
the thickening agent is: xanthan gum;
the chelating agent is: one or two of EDTA-2Na and EDTA-4 Na;
the ester-forming agent is: one or more of jojoba oil, tea seed oil, olive oil, and almond oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Has the advantages that:
the shower gel provided by the invention has the effects of bacteriostasis, anti-inflammation and moistening, can effectively avoid seborrheic dermatitis after being used for a long time, and moistens dry skin; the dendrobium officinale, the grassleaf sweelflag rhizome, the parasitic loranthus and the semiliquidambar cathayensis are common medicinal materials in river regions, and the research of the invention can promote the development of local traditional Chinese medicine industry.
Detailed Description
The following is a detailed description of the embodiments of the present invention, but the present invention is not limited to these embodiments, and any modifications or substitutions in the basic spirit of the embodiments are included in the scope of the present invention as claimed in the claims.
Example 1
The anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 0.1% of herbal extract, 30% of surfactant, 1% of humectant, 0.1% of thickener, 0.01% of chelating agent, 0.1% of ester-forming agent, 0.01% of preservative, 0.001% of essence and the balance of deionized water.
The herbal extract is prepared by grinding 3 parts of dendrobium officinale, 3 parts of rhizoma acori graminei, 2 parts of parasitic loranthus and 2 parts of semiliquidambar cathayensis in parts by weight, sieving the ground substances with a 20-mesh sieve, adding 40-50% ethanol solution which is 20 times of the total mass of the herbs, carrying out reflux extraction for 2 times, 1 hour each time, filtering and volatilizing ethanol to obtain the herbal extract.
The surfactant is: sodium cocoyl glycinate;
the humectant is glycerin;
the thickening agent is: xanthan gum;
the chelating agent is: EDTA-2 Na;
the ester-forming agent is: jojoba oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Example 2
The anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 5% of herbal extract, 60% of surfactant, 10% of humectant, 3% of thickener, 1% of chelating agent, 5% of excipient, 0.1% of preservative, 0.01% of essence and the balance of deionized water.
The herbal extract is prepared by grinding 6 parts of dendrobium officinale, 6 parts of rhizoma acori graminei, 5 parts of parasitic loranthus and 5 parts of semiliquidambar cathayensis in parts by weight, sieving the ground substances with a 30-mesh sieve, adding a 50% ethanol solution with the mass 30 times of the total herbs, carrying out reflux extraction for 2 times, carrying out 2 hours each time, filtering, and volatilizing ethanol to obtain the herbal extract.
The surfactant is: sodium laureth sulfate;
the humectant is glycerol;
the thickening agent is: xanthan gum;
the chelating agent is: EDTA-4 Na;
the ester-forming agent is: tea seed oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Example 3
The anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 0.5% of herbal extract, 340% of surfactant, 2% of humectant, 0.8% of thickener, 0.03% of chelating agent, 0.6% of ester-forming agent, 0.02% of preservative, 0.003% of essence and the balance of deionized water.
The herbal extract is prepared by crushing 4 parts of dendrobium officinale, 4 parts of rhizoma acori graminei, 3 parts of parasitic loranthus and 3 parts of semiliquidambar cathayensis in parts by weight, sieving the crushed materials with a 20-mesh sieve, adding 42% ethanol solution with the mass being 22 times of that of the total herbs, carrying out reflux extraction for 2 times, each time for 1.5 hours, filtering and volatilizing ethanol to obtain the herbal extract.
The surfactant is cocamidopropyl betaine;
the humectant is butanediol;
the thickening agent is: xanthan gum;
the chelating agent is: EDTA-2Na and EDTA-4 Na;
the ester-forming agent is: olive oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Example 4
The anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 2% of herbal extract, 45% of surfactant, 8% of humectant, 1.5% of thickener, 0.06% of chelating agent, 2.3% of ester-forming agent, 0.4% of preservative, 0.004% of essence and the balance of deionized water.
The herbal extract is prepared by crushing 5 parts by weight of dendrobium officinale, 5 parts by weight of rhizoma acori graminei, 4 parts by weight of parasitic loranthus and 4 parts by weight of semiliquidambar cathayensis, sieving the crushed materials with a 20-mesh sieve, adding a 45% ethanol solution with the mass 24 times of the total herbs, carrying out reflux extraction for 2 times, carrying out 1.2 hours each time, filtering, and volatilizing ethanol to obtain the herbal extract.
The surfactant is: one or more of sodium cocoyl glycinate, sodium laureth sulfate and cocamidopropyl betaine;
the humectant is sodium hyaluronate;
the thickening agent is: xanthan gum;
the chelating agent is: EDTA-2 Na;
the ester-forming agent is: almond oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Example 5
The anti-inflammatory herbal shower gel comprises the following raw materials in parts by weight: 4% of herbal extract, 55% of surfactant, 9% of humectant, 2.5% of thickening agent, 0.07% of chelating agent, 4.5% of ester-forming agent, 0.06% of preservative, 0.009% of essence and the balance of deionized water.
The herbal extract is prepared by grinding 3 parts by weight of dendrobium officinale, 6 parts by weight of rhizoma acori graminei, 2 parts by weight of parasitic loranthus and 5 parts by weight of semiliquidambar cathayensis, sieving the ground substances with a 20-mesh sieve, adding 40-50% ethanol solution which is 28 times of the total mass of the herbs, carrying out reflux extraction for 2 times, carrying out 1.8 hours each time, filtering, and volatilizing ethanol.
The surfactant is: one or more of sodium cocoyl glycinate, sodium laureth sulfate and cocamidopropyl betaine;
the humectant is a mixture of glycerol, butanediol, allantoin and sodium hyaluronate;
the thickening agent is: xanthan gum;
the chelating agent is: EDTA-2Na and EDTA-4 Na;
the ester-forming agent is: a mixture of jojoba oil, tea seed oil, olive oil, almond oil;
the preservative is methyl p-hydroxybenzoate.
The preparation method comprises the following steps:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
Comparative example 1
The body wash was prepared according to the method of patent No. CN 201810547925.6.
Experimental example 1
50 women with seborrheic dermatitis between 35 and 45 years old are selected as test objects, randomly divided into 10 persons in each group according to examples 1-5, bathed with the shower gel of the invention every day, and the improvement conditions of skin redness and swelling, pruritus and furuncle are investigated after one month.
Group of Number of effective people Number of effective persons Number of invalid persons Total effective number
Example 1 3 5 2 80%
Example 2 4 5 1 90%
Example 3 7 3 0 100%
Example 4 7 3 0 100%
Example 5 6 3 1 90%
Comparative example 1 4 3 3 70%

Claims (4)

1. The anti-inflammatory herbal shower gel is characterized by comprising the following raw materials in parts by weight: 0.1-5% of herbal extract, 30-60% of surfactant, 1-10% of humectant, 0.1-3% of thickener, 0.01-1% of chelating agent, 0.1-5% of excipient, 0.01-0.1% of preservative, 0.001-0.01% of essence and the balance of deionized water.
2. The anti-inflammatory herbal shower gel as claimed in claim 1, wherein the herbal extract is prepared by pulverizing 3-6 parts by weight of Dendrobium officinale, 3-6 parts by weight of Acorus gramineus, 2-5 parts by weight of Loranthus parasiticus and 2-5 parts by weight of Semiliquidambar cathayensis, sieving with 20-30 mesh sieve, adding 40-50% ethanol solution 20-30 times of the total weight of herbs, reflux extracting for 2 times, each for 1-2h, filtering, and volatilizing ethanol.
3. The anti-inflammatory herbal body wash of claim 1,
the surfactant is: one or more of sodium cocoyl glycinate, sodium laureth sulfate and cocamidopropyl betaine;
the humectant is one or more of glycerol, butanediol, allantoin and sodium hyaluronate;
the thickening agent is: xanthan gum;
the chelating agent is: one or two of EDTA-2Na and EDTA-4 Na;
the ester-forming agent is: one or more of jojoba oil, tea seed oil, olive oil, and almond oil;
the preservative is methyl p-hydroxybenzoate.
4. An anti-inflammatory herbal body wash as claimed in claims 1-3, prepared by the method of:
(1): mixing water, a surfactant and a humectant, adding into a heating device, heating to 95 ℃ to obtain a compound mixed solution;
(2): dissolving the herbal extract, passing through the pistil, adding the herbal extract into the compound mixed solution, and mixing to obtain a traditional Chinese medicine mixed solution;
(3): adding a thickening agent and a chelating agent into the traditional Chinese medicine mixed solution for mixing, standing and preserving heat after mixing, and carrying out third homogenization treatment after preserving heat to obtain a traditional Chinese medicine shower gel stock solution;
(4): cooling the shower gel stock solution, cooling the shower gel stock solution to a normal temperature state, adding an ester-forming agent and essence into the shower gel stock solution, mixing again, performing viscosity blending treatment to obtain the traditional Chinese medicine shower gel, and packaging.
CN201911295260.5A 2019-12-16 2019-12-16 Anti-inflammatory herbal shower gel Withdrawn CN112972345A (en)

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Application Number Priority Date Filing Date Title
CN201911295260.5A CN112972345A (en) 2019-12-16 2019-12-16 Anti-inflammatory herbal shower gel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
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Publications (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110200894A (en) * 2019-07-25 2019-09-06 广州市英姿化妆品有限公司 A kind of preparation method of Chinese medicine bath cream

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110200894A (en) * 2019-07-25 2019-09-06 广州市英姿化妆品有限公司 A kind of preparation method of Chinese medicine bath cream

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