CN112773765A - 治疗普拉德-威利综合征的方法 - Google Patents

治疗普拉德-威利综合征的方法 Download PDF

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Publication number
CN112773765A
CN112773765A CN202110278199.4A CN202110278199A CN112773765A CN 112773765 A CN112773765 A CN 112773765A CN 202110278199 A CN202110278199 A CN 202110278199A CN 112773765 A CN112773765 A CN 112773765A
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CN
China
Prior art keywords
carbetocin
day
substituted
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110278199.4A
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English (en)
Chinese (zh)
Inventor
帕斯卡尔·丹格拉斯
迈克尔·雷迪
保罗·考纳尔
苏达考迪·阿拉加萨米
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Firelink
Ferring BV
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Firelink
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Publication date
Application filed by Firelink filed Critical Firelink
Publication of CN112773765A publication Critical patent/CN112773765A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202110278199.4A 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法 Pending CN112773765A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462052957P 2014-09-19 2014-09-19
US62/052,957 2014-09-19
CN201580049147.2A CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201580049147.2A Division CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Publications (1)

Publication Number Publication Date
CN112773765A true CN112773765A (zh) 2021-05-11

Family

ID=54238564

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110278199.4A Pending CN112773765A (zh) 2014-09-19 2015-09-14 治疗普拉德-威利综合征的方法
CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Family Applications After (1)

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CN201580049147.2A Pending CN106714819A (zh) 2014-09-19 2015-09-14 治疗普拉德‑威利综合征的方法

Country Status (16)

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US (3) US10441627B2 (https=)
EP (2) EP3193907B1 (https=)
JP (3) JP6599447B2 (https=)
CN (2) CN112773765A (https=)
CA (1) CA2957224A1 (https=)
DK (1) DK3666258T3 (https=)
ES (2) ES2970059T3 (https=)
FI (1) FI3666258T3 (https=)
HR (1) HRP20240166T1 (https=)
HU (1) HUE065829T2 (https=)
LT (1) LT3666258T (https=)
PL (1) PL3666258T3 (https=)
PT (1) PT3666258T (https=)
RS (1) RS65144B1 (https=)
SI (1) SI3666258T1 (https=)
WO (1) WO2016044131A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20240166T1 (hr) 2014-09-19 2024-04-26 Ferring B.V. Postupak liječenja prader-willijevog sindroma
PT3665183T (pt) 2017-08-11 2025-03-10 Ferring Bv Método de preparação de uma composição farmacêutica
US20190135859A1 (en) 2017-08-11 2019-05-09 Ferring B.V. Method of manufacturing a pharmaceutical composition
US10736894B2 (en) 2018-02-15 2020-08-11 Ovid Therapeutics Inc. Methods of treating developmental syndromes with PDE10A inhibitors
KR20210062638A (ko) * 2018-09-20 2021-05-31 레보 테라퓨틱스 인코포레이티드 카르베토신의 안정한 비강내 제형
AU2019345313A1 (en) 2018-09-20 2021-03-18 Levo Therapeutics, Inc. Carbetocin drug product and process for preparing same
CA3205469A1 (en) * 2020-12-18 2022-06-23 The General Hospital Corporation Probiotics compositions and method of using the same to enhance growth and social function in children
HRP20250303T1 (hr) 2021-03-26 2025-05-09 Centre Hospitalier Universitaire De Toulouse Liječenje disfagije

Citations (3)

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CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

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US7544662B2 (en) 1993-06-17 2009-06-09 Carle Development Foundation Polypeptides useful for appetite suppression
US6894026B1 (en) 2000-01-11 2005-05-17 Atossa Healthcare, Inc. Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders
US20070032410A1 (en) 2000-01-11 2007-02-08 Atossa Healthcare, Inc. Compositions and methods for the treatment of psychiatric disorders
US9023793B2 (en) 2006-09-29 2015-05-05 Retrophin, Inc. Intranasal carbetocin formulations and methods for the treatment of autism
CN101677948A (zh) * 2007-06-07 2010-03-24 纳斯泰克制药公司 卡贝缩宫素鼻用制剂和治疗孤独症的方法
WO2009033665A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a rgd-peptide and/or parathyroid hormone (1-34 ) as anti-hiv agent
JP2010538979A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト S.Pneumoniaeの感染等を処置するための治療剤としての、RGDSPASSKP、および随意的なアンギオテンシンIIの使用
WO2009033820A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
JP2010539002A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト ウロジラチンの治療剤としての使用
DK2260053T3 (da) 2008-03-31 2014-06-23 Ferring Bv Oxytocin-analoger
CA2731020A1 (en) 2008-07-18 2010-01-21 Zafgen, Inc. Use of antiangiogenic fumagillins in the treatment of obesity
US20120108510A1 (en) 2010-05-20 2012-05-03 Emory University Methods of improving behavioral therapies
EP2575853B1 (en) 2010-05-25 2016-08-24 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient
WO2012149472A2 (en) 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
JP6067878B2 (ja) * 2012-12-21 2017-01-25 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft オキシトシンアゴニストとしてのペプチド
AU2015270723A1 (en) 2014-06-03 2016-11-17 F. Hoffmann-La Roche Ag Peptides as oxytocin agonists
CR20160562A (es) 2014-06-06 2017-01-06 Hoffmann La Roche Péptidos como agonistas de la oxitocina
CN106573958A (zh) 2014-08-07 2017-04-19 豪夫迈·罗氏有限公司 用于制备催产素类似物的方法
HRP20240166T1 (hr) * 2014-09-19 2024-04-26 Ferring B.V. Postupak liječenja prader-willijevog sindroma

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102656183A (zh) * 2009-09-21 2012-09-05 辉凌国际制药(瑞士)有限公司 催产素受体激动剂
CN103124554A (zh) * 2010-09-30 2013-05-29 辉凌公司 药物组合物
WO2014111356A1 (en) * 2013-01-17 2014-07-24 F. Hoffmann-La Roche Ag Oxytocin receptor agonists for the treatment of cns diseases

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Publication number Publication date
WO2016044131A1 (en) 2016-03-24
FI3666258T3 (fi) 2024-02-09
JP6921154B2 (ja) 2021-08-18
JP6599447B2 (ja) 2019-10-30
EP3193907A1 (en) 2017-07-26
US20170326200A1 (en) 2017-11-16
EP3666258A1 (en) 2020-06-17
ES2775425T3 (es) 2020-07-27
LT3666258T (lt) 2024-01-10
EP3666258B1 (en) 2023-11-15
US10441627B2 (en) 2019-10-15
HUE065829T2 (hu) 2024-06-28
RS65144B1 (sr) 2024-02-29
JP2017532316A (ja) 2017-11-02
US20200129584A1 (en) 2020-04-30
PT3666258T (pt) 2024-02-01
DK3666258T3 (da) 2024-02-05
JP2021098745A (ja) 2021-07-01
CN106714819A (zh) 2017-05-24
PL3666258T3 (pl) 2024-04-08
ES2970059T3 (es) 2024-05-24
US20240082344A1 (en) 2024-03-14
JP2020019790A (ja) 2020-02-06
EP3193907B1 (en) 2020-01-01
SI3666258T1 (sl) 2024-04-30
CA2957224A1 (en) 2016-03-24
HRP20240166T1 (hr) 2024-04-26

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