CN1127294C - 杀内/外寄生虫组合物 - Google Patents
杀内/外寄生虫组合物 Download PDFInfo
- Publication number
- CN1127294C CN1127294C CN97180962A CN97180962A CN1127294C CN 1127294 C CN1127294 C CN 1127294C CN 97180962 A CN97180962 A CN 97180962A CN 97180962 A CN97180962 A CN 97180962A CN 1127294 C CN1127294 C CN 1127294C
- Authority
- CN
- China
- Prior art keywords
- group
- ivermectin
- spp
- imidacloprid
- avermectins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 description 1
- 229940093471 ethyl oleate Drugs 0.000 description 1
- 125000006125 ethylsulfonyl group Chemical group 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000013505 freshwater Substances 0.000 description 1
- 125000002541 furyl group Chemical group 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 229940075507 glyceryl monostearate Drugs 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 125000001188 haloalkyl group Chemical group 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 125000005241 heteroarylamino group Chemical group 0.000 description 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- 230000020245 homoiothermy Effects 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- WFKAJVHLWXSISD-UHFFFAOYSA-N isobutyramide Chemical compound CC(C)C(N)=O WFKAJVHLWXSISD-UHFFFAOYSA-N 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical class CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 229960001614 levamisole Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 description 1
- ODDHBYXHXZCAGQ-UHFFFAOYSA-N methyl 2-anilinobenzoate Chemical class COC(=O)C1=CC=CC=C1NC1=CC=CC=C1 ODDHBYXHXZCAGQ-UHFFFAOYSA-N 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 125000001624 naphthyl group Chemical group 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 239000005645 nematicide Substances 0.000 description 1
- 125000000449 nitro group Chemical class [O-][N+](*)=O 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- BARWIPMJPCRCTP-UHFFFAOYSA-N oleic acid oleyl ester Natural products CCCCCCCCC=CCCCCCCCCOC(=O)CCCCCCCC=CCCCCCCCC BARWIPMJPCRCTP-UHFFFAOYSA-N 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 1
- 229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000003182 parenteral nutrition solution Substances 0.000 description 1
- 235000010603 pastilles Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 229960000490 permethrin Drugs 0.000 description 1
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 1
- 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- ATROHALUCMTWTB-OWBHPGMISA-N phoxim Chemical compound CCOP(=S)(OCC)O\N=C(\C#N)C1=CC=CC=C1 ATROHALUCMTWTB-OWBHPGMISA-N 0.000 description 1
- 229950001664 phoxim Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- DJEHXEMURTVAOE-UHFFFAOYSA-M potassium bisulfite Chemical compound [K+].OS([O-])=O DJEHXEMURTVAOE-UHFFFAOYSA-M 0.000 description 1
- 229940099427 potassium bisulfite Drugs 0.000 description 1
- 235000010259 potassium hydrogen sulphite Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical class CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 239000001944 prunus armeniaca kernel oil Substances 0.000 description 1
- 239000002728 pyrethroid Substances 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 150000004040 pyrrolidinones Chemical class 0.000 description 1
- 238000012207 quantitative assay Methods 0.000 description 1
- 229940108410 resmethrin Drugs 0.000 description 1
- VEMKTZHHVJILDY-FIWHBWSRSA-N resmethrin Chemical compound CC1(C)[C@H](C=C(C)C)C1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-FIWHBWSRSA-N 0.000 description 1
- 229960000581 salicylamide Drugs 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000004550 soluble concentrate Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical group [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 125000004213 tert-butoxy group Chemical group [H]C([H])([H])C(O*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Description
大环内酯 | -C22R1-X-C23R2- | R3 | R4 |
阿凡曼菌素A1a | -CH=CH- | 仲丁基 | -Me |
阿凡曼菌素A1b | -CH=CH- | 异丙基 | -Me |
阿凡曼菌素A2a | -CH2-CHOH- | 仲丁基 | -Me |
阿凡曼菌素A2b | -CH2-CHOH- | 异丙基 | -Me |
阿凡曼菌素B1a | -CH=CH- | 仲丁基 | -H |
阿凡曼菌素B1b | -CH=CH- | 异丙基 | -H |
阿凡曼菌素B2a | -CH2-CHOH- | 仲丁基 | -H |
阿凡曼菌素B2b | -CH2-CHOH- | 异丙基 | -H |
22,23-二氢阿凡曼菌B1a | -CH2-CH2- | 仲丁基 | -H |
22,23-二氢阿凡曼菌素B1b | -CH2-CH2- | 异丙基 | -H |
多拉美丁 | -CH=CH- | 环己基 | -H |
时间 天 | 每只狗中的跳蚤数量 | 活性% | |
未处理 | 处理后 | ||
-1 感染100只跳蚤 | |||
0 处理并计数 | 30 | 0 | 100 |
5,8 感染100只跳蚤 | |||
9 计数 | 56 | 0 | 100 |
15 感染100只跳蚤 | |||
16 计数 | 76 | 0 | 100 |
19 感染100只跳蚤(未处理动物)250只跳蚤(处理的动物) | |||
20 计数 | 39 | 0 | 100 |
26 感染100只跳蚤 | |||
27 计数 | 43 | 0 | 100 |
活性化合物和剂量(mg/kg) | 减少速率(%) | |
吡虫啉 | 50.0 | 0 |
异阿凡曼菌素B1a/B1b | 0.1 | 0 |
异阿凡曼菌素B1a/B1b+吡虫啉 | 50.00.1 | 100 |
吡虫啉 | 25.0 | 0 |
吡虫啉+异阿凡曼菌素B1a/B1b | 25.00.1 | >80 |
活性化合物和剂量(mg/kg) | 减少速率(%) | |
吡虫啉 | 50.0 | 0 |
异阿凡曼菌素B1a/B1b | 0.1 | <50 |
吡虫啉+异阿凡曼菌素B1a/B1b | 50.00.1 | 100 |
吡虫啉 | 25.0 | 0 |
吡虫啉+异阿凡曼菌素B1a/B1b | 25.00.1 | 100 |
吡虫啉 | 10.0 | 0 |
吡虫啉+异阿凡曼菌素B1a/B1b | 10.00.1 | >80 |
吡虫啉 | 5.0 | 0 |
吡虫啉+异阿凡曼菌素B1a/B1b | 5.00.1 | >80 |
制剂(吡虫啉%/异阿凡曼菌素%) | 活性 |
10/0.006 | 60% |
10/0.05 | 95% |
10/0.2 | 99% |
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19654079.8 | 1996-12-23 | ||
DE19654079A DE19654079A1 (de) | 1996-12-23 | 1996-12-23 | Endo-ekto-parasitizide Mittel |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1241908A CN1241908A (zh) | 2000-01-19 |
CN1127294C true CN1127294C (zh) | 2003-11-12 |
Family
ID=7816057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN97180962A Expired - Lifetime CN1127294C (zh) | 1996-12-23 | 1997-12-11 | 杀内/外寄生虫组合物 |
Country Status (23)
Country | Link |
---|---|
US (2) | US20030055089A1 (zh) |
EP (1) | EP0946099B1 (zh) |
JP (2) | JP4445593B2 (zh) |
KR (1) | KR100549093B1 (zh) |
CN (1) | CN1127294C (zh) |
AR (1) | AR010375A1 (zh) |
AU (1) | AU736083B2 (zh) |
BR (1) | BR9714236B1 (zh) |
CA (1) | CA2275657C (zh) |
DE (1) | DE19654079A1 (zh) |
DK (1) | DK0946099T3 (zh) |
ES (1) | ES2536970T3 (zh) |
HK (1) | HK1025014A1 (zh) |
HU (2) | HU230153B1 (zh) |
IL (2) | IL130330A0 (zh) |
NL (1) | NL300761I2 (zh) |
NZ (1) | NZ336344A (zh) |
PL (1) | PL201763B1 (zh) |
PT (1) | PT946099E (zh) |
RU (1) | RU2222193C2 (zh) |
TW (1) | TW448047B (zh) |
WO (1) | WO1998027817A1 (zh) |
ZA (1) | ZA9711496B (zh) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4443888A1 (de) * | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermal applizierbare Formulierungen von Parasitiziden |
DE19654079A1 (de) * | 1996-12-23 | 1998-06-25 | Bayer Ag | Endo-ekto-parasitizide Mittel |
FR2780857B1 (fr) * | 1998-07-07 | 2006-09-22 | Novartis Ag | Agent pesticide |
EP1215964A4 (en) * | 1999-09-22 | 2002-11-05 | Ashmont Holdings Ltd | POUR-ON COMPOSITION FOR SHEEP |
AUPQ634300A0 (en) * | 2000-03-20 | 2000-04-15 | Eli Lilly And Company | Synergistic formulations |
JP4972843B2 (ja) * | 2000-11-09 | 2012-07-11 | 住友化学株式会社 | 動物外部寄生虫防除用経皮投与剤 |
DE10117676A1 (de) * | 2001-04-09 | 2002-10-10 | Bayer Ag | Dermal applizierbare flüssige Formulierungen zur Bekämpfung von parasitierenden Insekten an Tieren |
ITPR20010061A1 (it) * | 2001-09-14 | 2003-03-14 | Bruno Corradi | Prodotto fitosanitario, in particolare per iniezioni in piante arboree, e relativo procedimento. |
EA007161B1 (ru) * | 2001-09-17 | 2006-08-25 | Эли Лилли Энд Компани | Пестицидные составы |
DE10207242A1 (de) * | 2002-02-21 | 2003-09-04 | Bayer Cropscience Ag | Synergistische insektizide Mischungen |
PL1610613T3 (pl) * | 2003-04-04 | 2017-06-30 | Merial, Inc. | Miejscowe preparaty weterynaryjne przeciw robakom |
WO2005007822A2 (en) * | 2003-07-09 | 2005-01-27 | Sentigen Biosciences, Inc. | Method for assaying protein-protein interaction |
US7396819B2 (en) * | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
US7582612B2 (en) * | 2004-03-12 | 2009-09-01 | Hartz Mountain Corporation | Multi-action anthelmintic formulations |
DE102004013527A1 (de) * | 2004-03-19 | 2005-10-06 | Bayer Healthcare Ag | Parasitizide Mittel |
JP5622218B2 (ja) * | 2004-09-08 | 2014-11-12 | シーバ アニマル ヘルス リミテッド ライアビリティ カンパニー | 局所用殺内部寄生虫及び殺外部寄生虫製剤 |
DE102004053964A1 (de) * | 2004-11-09 | 2006-05-11 | Bayer Healthcare Ag | Mittel gegen Demodikose |
US20060147485A1 (en) * | 2005-01-04 | 2006-07-06 | Morten Pedersen | Oil-in-water formulation of avermectins |
EP1849363A1 (en) * | 2006-03-09 | 2007-10-31 | Cheminova A/S | Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin |
WO2011027333A1 (en) * | 2009-09-07 | 2011-03-10 | Douglas Robert Cleverly | Granulated anthelmintic preparations and delivery systems |
US8980896B2 (en) * | 2009-12-17 | 2015-03-17 | Merial, Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
CN102057937A (zh) * | 2011-01-21 | 2011-05-18 | 赤峰市帅旗农药有限责任公司 | 噻虫啉与甲氨基阿维菌素苯甲酸盐的杀虫组合物 |
NZ622869A (en) * | 2014-03-24 | 2015-01-30 | Donaghys Ltd | Stable veterinary anthelmintic formulations |
US9913472B2 (en) * | 2014-06-24 | 2018-03-13 | Rotam Agrochem International Company Limited | Agrochemical formulation, method making, and method of using |
CN104094960B (zh) * | 2014-07-16 | 2016-06-08 | 甘肃省农业科学院植物保护研究所 | 一种当归处理剂及其制备方法和应用 |
MX359970B (es) * | 2014-08-12 | 2018-10-05 | Univ Mexico Nac Autonoma | Composición farmacéutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y método para obtener la misma. |
CN107318879B (zh) * | 2016-04-28 | 2021-07-06 | 江苏龙灯化学有限公司 | 一种杀虫组合物 |
CN107318863B (zh) * | 2016-04-28 | 2021-07-06 | 江苏龙灯化学有限公司 | 一种杀虫组合物 |
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GB2221621A (en) * | 1988-08-12 | 1990-02-14 | Merck & Co Inc | Synergistic antiparasitic combinations of avermectin and pyrantel |
WO1995033453A1 (de) * | 1994-06-07 | 1995-12-14 | Bayer Aktiengesellschaft | Agonisten und antagonisten der nicotinergen acetylcholinrezeptoren von insekten als endoparasitizide |
DE19519007A1 (de) * | 1995-05-24 | 1996-11-28 | Bayer Ag | Insektizide Mittel |
WO1996038165A2 (de) * | 1995-06-02 | 1996-12-05 | Bayer Aktiengesellschaft | Endoparasitizide mittel |
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US4199569A (en) | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
JPS57139012A (en) | 1981-02-23 | 1982-08-27 | Sankyo Co Ltd | Anthelmintic composition |
ZA842571B (en) * | 1983-04-07 | 1985-11-27 | Merck & Co Inc | Novel synergistic antiparasitic combinations |
NZ223200A (en) | 1988-01-15 | 1989-01-06 | Ancare Distributors | Anthelmintic compositions containing 2',5-dicloro-4'-nitrosalicylanilide and non aqueous carrier |
GB2224933A (en) | 1988-11-21 | 1990-05-23 | Merck & Co Inc | Synergistic antiparasitic combinations |
IE960441L (en) * | 1988-12-27 | 1990-06-27 | Takeda Chemical Industries Ltd | Guanidine derivatives, their production and insecticides |
DE69023454T2 (de) | 1989-09-11 | 1996-06-05 | American Cyanamid Co., Wayne, N.J. | 13-Alkyl-23-Imino und 13-Halo-23-Imino-Derivate von LL-F28249-Verbindungen und ihre Verwendung als Endo- und Ectoparasitizide, Insektizide, Akarizide und Nematozide Mittel. |
US5030650A (en) * | 1989-09-11 | 1991-07-09 | American Cyanamid Company | 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents |
NZ247278A (en) | 1991-02-12 | 1995-03-28 | Ancare Distributors | Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier |
DE4443888A1 (de) | 1994-12-09 | 1996-06-13 | Bayer Ag | Dermal applizierbare Formulierungen von Parasitiziden |
JPH08179796A (ja) * | 1994-12-21 | 1996-07-12 | Sony Corp | 音声符号化方法 |
EP0836851A1 (en) * | 1996-10-21 | 1998-04-22 | Virbac S.A. | Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions |
DE19654079A1 (de) * | 1996-12-23 | 1998-06-25 | Bayer Ag | Endo-ekto-parasitizide Mittel |
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1996
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1997
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- 1997-12-11 BR BRPI9714236-0A patent/BR9714236B1/pt not_active IP Right Cessation
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- 1997-12-11 HU HU0000600A patent/HU230153B1/hu active Protection Beyond IP Right Term
- 1997-12-11 NZ NZ336344A patent/NZ336344A/xx not_active IP Right Cessation
- 1997-12-11 PT PT97953783T patent/PT946099E/pt unknown
- 1997-12-11 WO PCT/EP1997/006926 patent/WO1998027817A1/de active IP Right Grant
- 1997-12-11 EP EP97953783.4A patent/EP0946099B1/de not_active Expired - Lifetime
- 1997-12-11 US US09/331,040 patent/US20030055089A1/en not_active Abandoned
- 1997-12-11 PL PL334181A patent/PL201763B1/pl unknown
- 1997-12-11 RU RU99115825/13A patent/RU2222193C2/ru active
- 1997-12-17 TW TW086119026A patent/TW448047B/zh not_active IP Right Cessation
- 1997-12-19 AR ARP970106069A patent/AR010375A1/es not_active Application Discontinuation
- 1997-12-22 ZA ZA9711496A patent/ZA9711496B/xx unknown
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1999
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2000
- 2000-07-14 HK HK00104344A patent/HK1025014A1/xx not_active IP Right Cessation
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2003
- 2003-07-03 US US10/613,819 patent/US20040014689A1/en not_active Abandoned
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2009
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2015
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2016
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GB2221621A (en) * | 1988-08-12 | 1990-02-14 | Merck & Co Inc | Synergistic antiparasitic combinations of avermectin and pyrantel |
WO1995033453A1 (de) * | 1994-06-07 | 1995-12-14 | Bayer Aktiengesellschaft | Agonisten und antagonisten der nicotinergen acetylcholinrezeptoren von insekten als endoparasitizide |
DE19519007A1 (de) * | 1995-05-24 | 1996-11-28 | Bayer Ag | Insektizide Mittel |
WO1996038165A2 (de) * | 1995-06-02 | 1996-12-05 | Bayer Aktiengesellschaft | Endoparasitizide mittel |
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