CN112675100A - Whitening skin care composition and preparation method thereof - Google Patents

Whitening skin care composition and preparation method thereof Download PDF

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Publication number
CN112675100A
CN112675100A CN202110167424.7A CN202110167424A CN112675100A CN 112675100 A CN112675100 A CN 112675100A CN 202110167424 A CN202110167424 A CN 202110167424A CN 112675100 A CN112675100 A CN 112675100A
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Prior art keywords
care composition
whitening
skin care
skin
parts
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李日源
陈诗峰
陈磊
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Guangzhou Regal Fine Chemical Co
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Guangzhou Regal Fine Chemical Co
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Priority to CN202110167424.7A priority Critical patent/CN112675100A/en
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Abstract

The invention discloses a whitening skin care composition and a preparation method thereof, wherein the whitening skin care composition comprises the following effective components in parts by weight: 0.2-3 parts of 4-butyl resorcinol; 0.1-5 parts of nicotinamide; 0.2-5 parts of resveratrol; 0.1-2 parts of 3-o-ethyl ascorbic acid; 0.3-3 parts of hydroxyethyl piperazine ethanesulfonic acid; the preparation method comprises the following steps: a water phase preparation step: adding nicotinamide and hydroxyethyl piperazine ethanesulfonic acid into water, and heating for dissolving to obtain a water phase; oil phase preparation: heating and dissolving resveratrol to obtain an oil phase; mixing: mixing the water phase and the oil phase, and then adding 4-butyl resorcinol and 3-o-ethyl ascorbic acid to obtain the whitening and skin-care composition; the whitening skin care composition has the effects of whitening and brightening skin and fading color spots, has obvious using effect, and can be used as an effective active substance of a skin external preparation.

Description

Whitening skin care composition and preparation method thereof
Technical Field
The invention relates to a whitening skin-care composition and a preparation method thereof, belonging to the technical field of skin-care compositions.
Background
The color of human skin mainly depends on the content and distribution of melanin, and the structural function and quantity of melanocytes directly influence the content of melanin in skin, which is a determinant factor for melanin production. The whitening principle of various whitening components of the skin care product is to inhibit the growth of melanin, reduce the generation of melanin, accelerate the metabolism of the melanin and then replenish water for the skin so as to achieve the whitening effect. Generally, lightening the pigmentation on the skin surface to achieve a whitening effect is a slow process.
Disclosure of Invention
In order to overcome the defects of the prior art, the first object of the invention is to provide a whitening and skin-care composition which has the effects of whitening and brightening skin and lightening color spots, has obvious using effect and can be used as an effective active substance of a skin external preparation.
The second purpose of the invention is to provide a preparation method of the whitening and skin-care composition.
The first purpose of the invention can be achieved by adopting the following technical scheme: a whitening skin care composition comprises the following effective components in parts by weight:
Figure BDA0002936572620000011
Figure BDA0002936572620000021
further, the composition comprises the following effective components in parts by weight:
Figure BDA0002936572620000022
further, the resveratrol is resveratrol liposome.
Further, 0.01-10 parts of lavender essential oil is also included.
Further comprises 0.1-5 parts of gentiana rigescens extract.
Further, a thickening agent is also included.
The second purpose of the invention can be achieved by adopting the following technical scheme: a method for preparing a whitening skin care composition comprises the following steps:
a water phase preparation step: adding nicotinamide and hydroxyethyl piperazine ethanesulfonic acid into water, and heating for dissolving to obtain a water phase;
oil phase preparation: heating and dissolving resveratrol to obtain an oil phase;
mixing: mixing the water phase and the oil phase, and adding 4-butyl resorcinol and 3-o-ethyl ascorbic acid to obtain the whitening and skin-care composition.
Further, in the aqueous phase preparation step, the heating temperature is 80-85 ℃.
Further, in the oil phase preparation step, the heating temperature is 80-85 ℃.
Further, a mixing step: mixing the water phase and the oil phase, adding 4-butyl resorcinol at 60 deg.C, cooling to 42 deg.C, and adding 3-o-ethyl ascorbic acid to obtain the skin whitening and caring composition.
Compared with the prior art, the invention has the beneficial effects that:
1. the whitening and skin-care composition has the effects of whitening and brightening skin and fading color spots;
2. the whitening skin care composition disclosed by the invention can be suitable for various types of skin, is mild and non-irritant, and has an obvious and quick effect.
Detailed Description
The invention will be further described with reference to specific embodiments:
the whitening and skin-care composition comprises the following effective components in parts by weight as shown in table 1:
TABLE 1 ingredients of whitening skin care compositions
Figure BDA0002936572620000031
Figure BDA0002936572620000041
Figure BDA0002936572620000051
A method of preparing a whitening skin care composition comprising:
a water phase preparation step: mixing the phase A components, and heating to 80-85 deg.C to dissolve to obtain water phase;
oil phase preparation: heating the phase B component to 80-85 deg.C to dissolve to obtain oil phase;
mixing: mixing the water phase and the oil phase, adding the phase C and the phase D at the temperature of 60 ℃, and adding the phase E and the phase F when the temperature is reduced to 42 ℃ to obtain the whitening and skin-care composition.
Examples 1 to 3:
the whitening skin care compositions of examples 1-3 include the following active ingredients in parts by weight as shown in table 2:
table 2 ingredients of whitening skin care compositions of examples 1-3
Figure BDA0002936572620000052
Figure BDA0002936572620000061
Figure BDA0002936572620000071
A method of preparing a whitening skin care composition comprising:
a water phase preparation step: mixing the phase A components, and heating to 80-85 deg.C to dissolve to obtain water phase;
oil phase preparation: heating the phase B component to 80-85 deg.C to dissolve to obtain oil phase;
mixing: mixing the water phase and the oil phase, adding the phase C and the phase D at the temperature of 60 ℃, and adding the phase E and the phase F when the temperature is reduced to 42 ℃ to obtain the whitening and skin-care composition.
Examples 1-3 were tested:
the blank was set as a conventional skin care product without whitening function, and 40 women aged 20-50 years were randomly divided into 4 groups for testing for 8 weeks, and their faces had skin blackened and blotchy due to sun exposure, working pressure, age, etc.
The test method comprises the following steps: in the testing period, after the face is cleaned and refreshed in the morning and evening every day, a proper amount of the whitening composition is applied to the facial skin, the face is massaged until the whitening composition is absorbed, the color spot position can be repeatedly applied, the testing period is 8 weeks, and the whitening composition is matched with a sunscreen product during the testing period.
The results of the MC680 skin test instrument on the changes in melanin in the skin before and after use are shown in Table 3.
Before detection, the basic value D1 of melanin in skin is measured, then the value D2 of melanin in different periods is measured, then the melanin reduction ratio X0 is calculated according to the basic value D1 and D2 of the melanin before detection, X0 is (D1-D2)/D1 is 100 percent,
Figure BDA0002936572620000081
values are mean values from X0 of the subject,
Figure BDA0002936572620000082
the higher the value, the more the melanin reduction, the better the whitening effect,
Figure BDA0002936572620000083
it is considered that there is no whitening effect,
Figure BDA0002936572620000084
it is considered to be effective, but the effect is not good,
Figure BDA0002936572620000085
it is considered that there is a whitening effect,
Figure BDA0002936572620000086
it is considered to have an obvious whitening effect.
Table 3 melanin test results
Figure BDA0002936572620000087
As can be seen from Table 3, in the blank case where no whitening component was added,
Figure BDA0002936572620000088
the change was very small, the amount of melanin was almost unchanged, and the whitening effect was almost considered to be absent, whereas the examples had good whitening effect in about two weeks.
The MC680 skin detector detects the change in skin color before and after use:
the method has the following advantages: the facial skin of the testee is obviously improved, the skin color is obviously improved, and the roughness of the facial skin is obviously improved;
in general: the skin color, roughness and the like of the facial skin of the testee are improved compared with those before the test, but the improvement amplitude is not obvious;
and (4) invalidation: the skin color, roughness and the like of the facial skin of the testee are not changed compared with those before the test.
The results are shown in table 4:
table 4 skin color test results
Figure BDA0002936572620000091
As can be seen from Table 4, the skin tone of the blank remained substantially unchanged after 8 weeks of testing, but the skin tone was significantly improved in examples 1-3.
Various other changes and modifications to the above-described embodiments and concepts will become apparent to those skilled in the art from the above description, and all such changes and modifications are intended to be included within the scope of the present invention as defined in the appended claims.

Claims (10)

1. The whitening skin care composition is characterized by comprising the following effective components in parts by weight:
Figure FDA0002936572610000011
2. the whitening skin care composition of claim 1, comprising the following active ingredients in parts by weight:
Figure FDA0002936572610000012
3. the whitening skin care composition of claim 1, wherein the resveratrol is resveratrol liposome.
4. The whitening skin care composition of claim 1, further comprising 0.01-10 parts of lavender essential oil.
5. The whitening skin care composition of claim 1, further comprising 0.1-5 parts of gentiana rigescens extract.
6. The whitening skin care composition of claim 1, further comprising a thickener.
7. A preparation method of a whitening skin care composition is characterized by comprising the following steps:
a water phase preparation step: adding nicotinamide and hydroxyethyl piperazine ethanesulfonic acid into water, and heating for dissolving to obtain a water phase;
oil phase preparation: heating and dissolving resveratrol to obtain an oil phase;
mixing: mixing the water phase and the oil phase, and adding 4-butyl resorcinol and 3-o-ethyl ascorbic acid to obtain the whitening and skin-care composition.
8. The method of preparing a whitening skin care composition according to claim 1, wherein the heating temperature in the aqueous phase preparation step is 80-85 ℃.
9. The method of preparing a whitening skin care composition according to claim 1, wherein the heating temperature in the oil phase preparation step is 80-85 ℃.
10. The method of preparing a whitening skin care composition of claim 1, wherein the mixing step: mixing the water phase and the oil phase, adding 4-butyl resorcinol at 60 deg.C, cooling to 42 deg.C, and adding 3-o-ethyl ascorbic acid to obtain the skin whitening and caring composition.
CN202110167424.7A 2021-02-05 2021-02-05 Whitening skin care composition and preparation method thereof Pending CN112675100A (en)

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CN113332212A (en) * 2021-06-28 2021-09-03 深圳华信健康产业有限公司 Whitening composition and preparation method and application thereof
CN113350220A (en) * 2021-07-23 2021-09-07 杭州雅妍化妆品有限公司 Whitening 5D compound with synergistic whitening effect and application and preparation method thereof
CN113368003A (en) * 2021-06-25 2021-09-10 广州环亚化妆品科技有限公司 Composition with overnight muscle repairing effect and preparation method and application thereof
CN113648257A (en) * 2021-09-16 2021-11-16 广州芳利医药科技有限公司 Whitening and freckle-removing composition and preparation method and application thereof
CN115919676A (en) * 2023-03-11 2023-04-07 广州华厦生物制药有限公司 Whitening and freckle-removing porcelain cream for cleaning face

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Publication number Priority date Publication date Assignee Title
CN113368003A (en) * 2021-06-25 2021-09-10 广州环亚化妆品科技有限公司 Composition with overnight muscle repairing effect and preparation method and application thereof
CN113332212A (en) * 2021-06-28 2021-09-03 深圳华信健康产业有限公司 Whitening composition and preparation method and application thereof
CN113332212B (en) * 2021-06-28 2023-03-31 深圳华信健康产业有限公司 Whitening composition and preparation method and application thereof
CN113350220A (en) * 2021-07-23 2021-09-07 杭州雅妍化妆品有限公司 Whitening 5D compound with synergistic whitening effect and application and preparation method thereof
CN113648257A (en) * 2021-09-16 2021-11-16 广州芳利医药科技有限公司 Whitening and freckle-removing composition and preparation method and application thereof
CN115919676A (en) * 2023-03-11 2023-04-07 广州华厦生物制药有限公司 Whitening and freckle-removing porcelain cream for cleaning face
CN115919676B (en) * 2023-03-11 2023-05-09 广州华厦生物制药有限公司 Whitening and freckle removing cream for face cleaning and porcelain

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