CN112618433B - Natural casein mild moisturizing washing product - Google Patents
Natural casein mild moisturizing washing product Download PDFInfo
- Publication number
- CN112618433B CN112618433B CN202011584505.9A CN202011584505A CN112618433B CN 112618433 B CN112618433 B CN 112618433B CN 202011584505 A CN202011584505 A CN 202011584505A CN 112618433 B CN112618433 B CN 112618433B
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- China
- Prior art keywords
- moisturizing
- mild
- sodium
- natural casein
- water
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- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 24
- 238000005406 washing Methods 0.000 title claims abstract description 21
- 239000005018 casein Substances 0.000 title claims abstract description 16
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 title claims abstract description 16
- 235000021240 caseins Nutrition 0.000 title claims abstract description 16
- 102000011632 Caseins Human genes 0.000 claims abstract description 42
- 108010076119 Caseins Proteins 0.000 claims abstract description 42
- 229940080237 sodium caseinate Drugs 0.000 claims abstract description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000004094 surface-active agent Substances 0.000 claims abstract description 20
- 239000003906 humectant Substances 0.000 claims abstract description 11
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 10
- 239000002738 chelating agent Substances 0.000 claims abstract description 7
- 239000003755 preservative agent Substances 0.000 claims abstract description 6
- 230000002335 preservative effect Effects 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 15
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 15
- 238000001816 cooling Methods 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 10
- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- 229940079886 disodium lauryl sulfosuccinate Drugs 0.000 claims description 7
- KHIQYZGEUSTKSB-UHFFFAOYSA-L disodium;4-dodecoxy-4-oxo-3-sulfobutanoate Chemical compound [Na+].[Na+].CCCCCCCCCCCCOC(=O)C(S(O)(=O)=O)CC([O-])=O.CCCCCCCCCCCCOC(=O)C(S(O)(=O)=O)CC([O-])=O KHIQYZGEUSTKSB-UHFFFAOYSA-L 0.000 claims description 7
- 238000004090 dissolution Methods 0.000 claims description 7
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 5
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 5
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 229940119170 jojoba wax Drugs 0.000 claims description 4
- 229960005323 phenoxyethanol Drugs 0.000 claims description 4
- 108700004121 sarkosyl Proteins 0.000 claims description 4
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 4
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims description 4
- 240000001548 Camellia japonica Species 0.000 claims description 3
- 235000005976 Citrus sinensis Nutrition 0.000 claims description 3
- 240000002319 Citrus sinensis Species 0.000 claims description 3
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 3
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 3
- 235000018597 common camellia Nutrition 0.000 claims description 3
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 3
- 239000010502 orange oil Substances 0.000 claims description 3
- 229940101267 panthenol Drugs 0.000 claims description 3
- 239000011619 pantothenol Substances 0.000 claims description 3
- 235000020957 pantothenol Nutrition 0.000 claims description 3
- 229940065859 sodium cocoyl glycinate Drugs 0.000 claims description 3
- -1 sodium lauroyl aminopropionate Chemical compound 0.000 claims description 3
- IKGKWKGYFJBGQJ-UHFFFAOYSA-M sodium;2-(dodecanoylamino)acetate Chemical compound [Na+].CCCCCCCCCCCC(=O)NCC([O-])=O IKGKWKGYFJBGQJ-UHFFFAOYSA-M 0.000 claims description 3
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 2
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 2
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 2
- 229960005150 glycerol Drugs 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 229960004063 propylene glycol Drugs 0.000 claims description 2
- 239000002453 shampoo Substances 0.000 claims description 2
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 2
- 229940098386 usnea barbata extract Drugs 0.000 claims description 2
- 235000011201 Ginkgo Nutrition 0.000 claims 1
- 244000194101 Ginkgo biloba Species 0.000 claims 1
- 235000008100 Ginkgo biloba Nutrition 0.000 claims 1
- 244000170916 Paeonia officinalis Species 0.000 claims 1
- 230000002421 anti-septic effect Effects 0.000 claims 1
- 230000003750 conditioning effect Effects 0.000 claims 1
- 238000004140 cleaning Methods 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 6
- 239000002537 cosmetic Substances 0.000 abstract description 4
- 230000009982 effect on human Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 230000000638 stimulation Effects 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 239000000344 soap Substances 0.000 description 11
- 230000000052 comparative effect Effects 0.000 description 9
- UYTOHYBIBPDOKX-UHFFFAOYSA-N 2-(dodecanoylamino)propanoic acid Chemical compound CCCCCCCCCCCC(=O)NC(C)C(O)=O UYTOHYBIBPDOKX-UHFFFAOYSA-N 0.000 description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 6
- 239000011734 sodium Substances 0.000 description 6
- 229910052708 sodium Inorganic materials 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 239000006260 foam Substances 0.000 description 4
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 241000736199 Paeonia Species 0.000 description 2
- 206010040880 Skin irritation Diseases 0.000 description 2
- 230000036074 healthy skin Effects 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 239000005445 natural material Substances 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 230000036556 skin irritation Effects 0.000 description 2
- 231100000475 skin irritation Toxicity 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- OHVLMTFVQDZYHP-UHFFFAOYSA-N 1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-2-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]ethanone Chemical compound N1N=NC=2CN(CCC=21)C(CN1CCN(CC1)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)=O OHVLMTFVQDZYHP-UHFFFAOYSA-N 0.000 description 1
- HMUNWXXNJPVALC-UHFFFAOYSA-N 1-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)C(CN1CC2=C(CC1)NN=N2)=O HMUNWXXNJPVALC-UHFFFAOYSA-N 0.000 description 1
- LDXJRKWFNNFDSA-UHFFFAOYSA-N 2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-1-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]ethanone Chemical compound C1CN(CC2=NNN=C21)CC(=O)N3CCN(CC3)C4=CN=C(N=C4)NCC5=CC(=CC=C5)OC(F)(F)F LDXJRKWFNNFDSA-UHFFFAOYSA-N 0.000 description 1
- WZFUQSJFWNHZHM-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]-1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethanone Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)CC(=O)N1CC2=C(CC1)NN=N2 WZFUQSJFWNHZHM-UHFFFAOYSA-N 0.000 description 1
- 239000009429 Ginkgo biloba extract Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005238 degreasing Methods 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 229940068052 ginkgo biloba extract Drugs 0.000 description 1
- 235000020686 ginkgo biloba extract Nutrition 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
Abstract
The invention relates to the field of cosmetics, in particular to a mild moisturizing washing article of natural casein. The washing article comprises the following raw materials in percentage by mass: 3-10% of sodium caseinate, 8-15% of auxiliary surfactant, 3-8% of humectant, 0.1-0.5% of chelating agent, 0.1-2% of conditioner, 0.1-1% of preservative, 0-5% of pearling agent, 0.1-0.5% of essence and the balance of water. The washing product of the invention takes the water-soluble protein sodium caseinate as a natural surfactant, a thickener and a humectant, and is compounded with the auxiliary surfactant, the humectant and other components, thereby ensuring deep cleaning of skin and hair and simultaneously having moisturizing effect, no toxic or side effect on human body, natural green, mild and no stimulation.
Description
Technical Field
The invention relates to the field of cosmetics, in particular to a mild moisturizing washing article of natural casein.
Background
Skin cleansing cosmetics can be largely divided into two categories, one category being soap-based surfactant systems and one category being non-soap-based surfactant systems. For a long time, soap-based products occupy most of the market due to their good easy-to-rinse characteristics. However, soap-based products have high pH, strong irritation and degreasing capability, and the skin feel tight and uncomfortable after face cleaning, and the soap-based products are easy to damage the skin after long-term use.
Non-soap based washing products are a class of washing products that use non-soap based surfactants as the primary surfactant. In recent years, a plurality of large factories abroad put forward skin cleaning products formed by compounding non-soap-based surfactants. However, currently commercially available non-soap based detergents are mainly based on chemically synthesized surfactants, which are much softer than soap bases but still potentially harmful to the human body. Aiming at the existing market gap, the washing product with mild foam, moisturizing and cleaning effects and taking natural substances as main raw materials is particularly important. And the washing products are used as daily chemicals which are indispensable to modern people, and have wide market space.
Disclosure of Invention
Aiming at the defects existing in the prior art, the invention provides a natural casein mild moisturizing washing product which uses sodium caseinate as a main surfactant, is compounded with components such as a green mild surfactant, a humectant and the like, can realize deep cleaning of skin, moisturizes and protects the skin, is easy to wash, and has small skin irritation.
The specific scheme is as follows: a natural casein mild moisturizing washing article comprises the following components in percentage by mass: 3-10% of sodium caseinate, 8-15% of auxiliary surfactant, 3-8% of humectant, 0.1-0.5% of chelating agent, 0.1-2% of conditioner, 0.1-1% of preservative, 0-5% of pearling agent, 0.1-0.5% of essence and the balance of water.
The auxiliary surfactant is at least one of sodium lauroyl sarcosinate, sodium lauroyl aminopropionate, cocamidopropyl betaine, sodium cocoyl glycinate and disodium lauryl sulfosuccinate monoester.
The humectant is at least one of glycerol, propylene glycol, panthenol and sodium hyaluronate.
The chelating agent is at least one of disodium EDTA and tetrasodium EDTA.
The conditioner is at least one of jojoba oil, camellia seed oil and sweet orange oil.
The preservative is at least one of DMDM hydantoin, phenoxyethanol, ginkgo biloba extract and peony extract, and Usnea barbata extract.
The preparation method of the natural casein mild moisturizing washing product comprises the following steps:
s1, taking 100mL of prepared product as a reference, adding 50mL of water into a container, and heating to 60 ℃;
s2, adding sodium caseinate for dissolution, keeping the temperature for 30min, and stirring while heating to enable the sodium caseinate to be fully dissolved in water;
s3, sequentially adding auxiliary surfactant, humectant and conditioner according to a proportion. And cooling to 45 ℃, and adding the chelating agent, the preservative, the essence and the pearling agent.
S4, adding deionized water to a volume of 100mL, continuously stirring, fully and uniformly mixing the system, and keeping a stable state.
S5, cooling and standing the obtained mixture for 24-36h, and filling the mixture into a container which is sterilized in advance.
The invention has the beneficial effects that: the skin deep cleaning agent takes sodium caseinate as a main surfactant, and is compounded with components such as a green mild surfactant, a humectant and the like, so that skin deep cleaning can be realized simultaneously, and meanwhile, the skin is not sticky and tight after washing due to the fact that the nonionic soap-based surfactant is compounded, washing is easy. In addition, because the sodium caseinate is a natural substance, the skin irritation is small, on the premise of ensuring that the skin and hair are soft and have no irritation, the skin can be deeply cleaned, sebum and cuticle fragments adhered to the surfaces of the skin and the scalp and residues of beauty cosmetics adhered to the cuticle fragments and the cuticle fragments are removed, and meanwhile, the effects of moisturizing and protecting the skin and nourishing the scalp are achieved, and the process is mild and safe and has no toxic or side effect on human bodies.
Detailed Description
The invention will be further described with reference to specific examples:
example 1
The natural casein mild moisturizing facial cleanser disclosed by the embodiment comprises the following raw materials in percentage by mass:
based on 100mL of the prepared product, 50mL of water is added into a three-necked flask, the temperature is heated to 60 ℃, then 5% sodium caseinate is added for dissolution, the temperature is kept for 30min, and the sodium caseinate is fully dissolved in the water while being heated and stirred. Then adding 8% of sodium lauramidopropionate, 6% of sodium lauroyl sarcosinate, 4% of glycerol, 2% of propylene glycol and 0.8% of jojoba oil according to the proportion, and stirring until the mixture is completely dissolved. Cooling to 45deg.C, adding 0.1% EDTA disodium, 1% DMDM hydantoin, 2% pearling agent, and 0.5% essence. And finally adding deionized water to a constant volume of 100mL, and continuously stirring for 1h to ensure that the system is fully and uniformly mixed, and keeping a stable state. Cooling and standing the obtained mixture for 24-36h, and placing the mixture into a container which is sterilized in advance.
Comparative examples 1 to 1
The difference from example 1 is that sodium lauramidopropionate is used instead of sodium caseinate.
Comparative examples 1 to 2
The difference from example 1 is that disodium lauryl sulfosuccinate monoester is used instead of sodium caseinate.
Example 2
The natural casein mild moisturizing body wash disclosed by the embodiment comprises the following raw materials in percentage by mass:
based on 100mL of the prepared product, 50mL of water is added into a three-necked flask, the temperature is heated to 60 ℃, then 6% sodium caseinate is added for dissolution, the temperature is kept for 30min, and the sodium caseinate is fully dissolved in the water while being heated and stirred. Then 8% of cocamidopropyl betaine, 6% of sodium cocoyl glycinate, 4% of glycerol, 2% of panthenol and 0.8% of jojoba oil are added according to the proportion, and stirred until the mixture is completely dissolved. Cooling to 45deg.C, adding 0.1% EDTA disodium, 0.5% phenoxyethanol, 2% pearling agent, and 0.5% essence. And finally adding deionized water to a constant volume of 100mL, and continuously stirring for 1h to ensure that the system is fully and uniformly mixed, and keeping a stable state. Cooling and standing the obtained mixture for 24-36h, and placing the mixture into a container which is sterilized in advance.
Comparative example 2-1
The difference from example 2 is that sodium lauramidopropionate is used instead of sodium caseinate.
Comparative examples 2 to 2
The difference from example 2 is that disodium lauryl sulfosuccinate monoester is used instead of sodium caseinate.
Example 3
The natural casein mild moisturizing shampoo disclosed by the embodiment is prepared from the following raw materials in percentage by mass:
based on 100mL of the prepared product, 50mL of water is added into a three-necked flask, the temperature is heated to 60 ℃, then 3% sodium caseinate is added for dissolution, the temperature is kept for 30min, and the sodium caseinate is fully dissolved in the water while being heated and stirred. Then 8% of sodium lauroyl sarcosinate, 5% of disodium lauryl sulfosuccinate monoester, 2% of cocamidopropyl betaine, 5% of propylene glycol and 0.5% of sweet orange oil are added according to the proportion, and the mixture is stirred until the mixture is completely dissolved. Cooling to 45deg.C, adding 5% pearling agent, 0.1% EDTA disodium, 1% peony extract, and 0.5% essence. And finally adding deionized water to a constant volume of 100mL, and continuously stirring for 1h to ensure that the system is fully and uniformly mixed, and keeping a stable state. Cooling and standing the obtained mixture for 24-36h, and placing the mixture into a container which is sterilized in advance.
Comparative example 3-1
The difference from example 3 is that sodium lauramidopropionate is used instead of sodium caseinate.
Comparative example 3-2
The difference from example 3 is that disodium lauryl sulfosuccinate monoester is used instead of sodium caseinate.
Example 4
The mild moisturizing hand sanitizer containing the natural casein consists of the following raw materials in percentage by mass:
based on 100mL of the prepared product, 50mL of water is added into a three-necked flask, the temperature is heated to 60 ℃, then 8% sodium caseinate is added for dissolution, the temperature is kept for 30min, and the sodium caseinate is fully dissolved in the water while being heated and stirred. Then adding 8% of sodium lauramidopropionate, 6% of cocamidopropyl betaine, 4% of glycerol, 2% of propylene glycol and 0.8% of camellia seed oil according to the proportion, and stirring until the mixture is completely dissolved. Cooling to 45deg.C, adding 0.1% EDTA tetrasodium, 0.5% phenoxyethanol, 5% pearling agent, and 0.5% essence. And finally adding deionized water to a constant volume of 100mL, and continuously stirring for 1h to ensure that the system is fully and uniformly mixed, and keeping a stable state. Cooling and standing the obtained mixture for 24-36h, and placing the mixture into a container which is sterilized in advance.
Comparative example 4-1
The difference from example 4 is that sodium lauramidopropionate is used instead of sodium caseinate.
Comparative example 4-2
The difference from example 4 is that disodium lauryl sulfosuccinate monoester was used instead of sodium caseinate.
Stability test: the samples were placed in a 40 ℃ constant temperature and humidity cabinet and inspected for 30 days, and whether the appearance of the samples had delamination or other changes was observed every 5 days.
Foam bottle testing. 1g of sample was taken, 49g of deionized water was added for sufficient dissolution, and then the aqueous solution was slowly poured into a graduated foam bottle and shaken up and down for 20 times to observe the foam height (cm).
Rinse performance and feel in use. Healthy skin subjects were randomly selected in 20 subjects, each half of men and women, and randomly divided into 5 groups of 4 persons each. Healthy skin 5cm x 5cm inside the arm of the subject was selected and lipstick was evenly applied thereon. The skin coated with lipstick was moistened with water, the products prepared in examples and comparative examples were respectively extruded into the above moistened areas by a pump, and after 30s of massage, the skin was rinsed with water, the moisturizing effect, the degree of easy rinsing, the cleansing effect and the feeling of skin after washing were recorded, evaluated by a score-giving machine, and the score-giving machine was divided into full scores of 10, and the average value was calculated.
Test effect record
Claims (5)
1. A natural casein mild moisturizing washing article, characterized in that: the components comprise the following components in percentage by mass: 3-10% of sodium caseinate, 8-15% of auxiliary surfactant, 3-8% of humectant, 0.1-0.5% of chelating agent, 0.1-2% of conditioner, 0.1-1% of preservative, 0-5% of pearling agent, 0.1-0.5% of essence and the balance of water; the humectant is at least one of glycerol, propylene glycol, panthenol and sodium hyaluronate;
the auxiliary surfactant is at least one of sodium lauroyl sarcosinate, sodium lauroyl aminopropionate, cocamidopropyl betaine, sodium cocoyl glycinate and disodium lauryl sulfosuccinate monoester;
the preservative is at least one of DMDM hydantoin, phenoxyethanol, ginkgo extract, peony extract and Usnea barbata extract.
2. A natural casein mild moisturizing washing according to claim 1, wherein said chelating agent is at least one of disodium EDTA and tetrasodium EDTA.
3. A natural casein mild moisturizing washing according to claim 1, wherein the conditioning agent is at least one of jojoba oil, camellia seed oil, sweet orange oil.
4. A process for the preparation of a natural casein mild moisturizing washing according to any one of claims 1 to 3, wherein: s1, taking 100mL of prepared product as a reference, adding 50mL of water into a container, and heating to 60 ℃;
s2, adding sodium caseinate for dissolution, keeping the temperature for 30min, and stirring while heating to enable the sodium caseinate to be fully dissolved in water;
s3, sequentially adding auxiliary surfactant, humectant and conditioner according to a proportion; cooling to 45deg.C, adding chelating agent, antiseptic, essence, and pearling agent;
s4, adding deionized water to a volume of 100mL, continuously stirring to ensure that the system is fully and uniformly mixed, and keeping a stable state;
s5, cooling and standing the obtained mixture for 24-36h, and filling the mixture into a container which is sterilized in advance.
5. Use of natural casein mild moisturizing washing products according to any one of claims 1 to 3, for moisturizing hand washes, moisturizing face washes, moisturizing shampoos, moisturizing body washes.
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