CN1126072A - 减低眼内压的眼用制剂 - Google Patents
减低眼内压的眼用制剂 Download PDFInfo
- Publication number
- CN1126072A CN1126072A CN95103537A CN95103537A CN1126072A CN 1126072 A CN1126072 A CN 1126072A CN 95103537 A CN95103537 A CN 95103537A CN 95103537 A CN95103537 A CN 95103537A CN 1126072 A CN1126072 A CN 1126072A
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- CN
- China
- Prior art keywords
- intraocular pressure
- propionyloxy
- dimethylamino
- ophthalmic
- reducing intraocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 229940067107 phenylethyl alcohol Drugs 0.000 description 1
- 229960001416 pilocarpine Drugs 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 230000036454 renin-angiotensin system Effects 0.000 description 1
- 230000004264 retinal detachment Effects 0.000 description 1
- 239000003215 serotonin 5-HT2 receptor antagonist Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 235000019830 sodium polyphosphate Nutrition 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 201000003826 superficial keratitis Diseases 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229940127230 sympathomimetic drug Drugs 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 229960004605 timolol Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 208000008281 urolithiasis Diseases 0.000 description 1
- 230000004382 visual function Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8717094 | 1994-03-18 | ||
| JP87170/94 | 1994-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1126072A true CN1126072A (zh) | 1996-07-10 |
Family
ID=13907523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95103537A Pending CN1126072A (zh) | 1994-03-18 | 1995-03-17 | 减低眼内压的眼用制剂 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5652272A (enExample) |
| EP (1) | EP0686393B1 (enExample) |
| KR (1) | KR100338053B1 (enExample) |
| CN (1) | CN1126072A (enExample) |
| AT (1) | ATE166227T1 (enExample) |
| CA (1) | CA2144810A1 (enExample) |
| DE (1) | DE69502539T2 (enExample) |
| ES (1) | ES2116681T3 (enExample) |
| TW (1) | TW309426B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998467A (en) * | 1995-10-25 | 1999-12-07 | Mitsubishi Chemical Corporation | Medicine for oculopathy |
| US6960579B1 (en) | 1998-05-19 | 2005-11-01 | Alcon Manufacturing, Ltd. | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders |
| ATE310566T1 (de) | 1998-09-18 | 2005-12-15 | Alcon Mfg Ltd | 5ht2-agoniste zur behandlung des glaukoms |
| WO2001058487A1 (en) * | 2000-02-09 | 2001-08-16 | Mitsubishi Pharma Corporation | Therapeutic and/or preventive agents for optic nerve diseases and retinal diseases |
| US6903081B2 (en) * | 2000-03-31 | 2005-06-07 | Purdue Research Foundation | Phosphoramidates and methods therefor |
| WO2003026636A1 (en) * | 2001-09-26 | 2003-04-03 | Mitsubishi Pharma Corporation | Thrombus/thrombogenesis inhibitors |
| JP2005511764A (ja) * | 2001-12-14 | 2005-04-28 | アルコン，インコーポレイテッド | 緑内障の処置のためのアミノアルキルベンゾフラン−５−オール化合物 |
| TW593302B (en) * | 2001-12-20 | 2004-06-21 | Alcon Inc | Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma |
| CN1678302A (zh) * | 2002-08-30 | 2005-10-05 | 爱尔康公司 | 取代的5－苯并二氢吡喃－5－基－乙胺化合物及其在治疗青光眼中的用途 |
| WO2004054572A2 (en) * | 2002-12-13 | 2004-07-01 | Alcon, Inc. | Novel benzopyran analogs and their use for the treatment of glaucoma |
| CA2839898C (en) * | 2003-06-13 | 2017-01-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| US7947295B2 (en) * | 2003-06-13 | 2011-05-24 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of two polymers |
| US7914803B2 (en) | 2003-06-13 | 2011-03-29 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of three polymers |
| TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| WO2005053688A1 (en) * | 2003-11-26 | 2005-06-16 | Alcon, Inc. | Substituted furo[2,3-g] indazoles for the treatment of glaucoma |
| US7129257B1 (en) * | 2003-12-15 | 2006-10-31 | Alcon, Inc. | Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma |
| US7338972B1 (en) | 2003-12-15 | 2008-03-04 | Alcon, Inc. | Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma |
| AR046890A1 (es) * | 2003-12-15 | 2005-12-28 | Alcon Inc | [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma. |
| US7425572B2 (en) | 2004-12-08 | 2008-09-16 | Alcon, Inc. | Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma |
| TW200744567A (en) * | 2005-09-23 | 2007-12-16 | Alcon Inc | Phenylethylamine analogs and their use for treating glaucoma |
| WO2007149728A2 (en) * | 2006-06-20 | 2007-12-27 | Alcon Research, Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| US20080193407A1 (en) * | 2007-02-09 | 2008-08-14 | Alcon, Inc. | Ophthalmic compositions containing a synergistic combination of three polymers |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02304022A (ja) * | 1989-05-18 | 1990-12-17 | Mitsubishi Kasei Corp | セロトニン拮抗剤 |
-
1995
- 1995-03-15 DE DE69502539T patent/DE69502539T2/de not_active Expired - Fee Related
- 1995-03-15 US US08/404,315 patent/US5652272A/en not_active Expired - Fee Related
- 1995-03-15 AT AT95301727T patent/ATE166227T1/de not_active IP Right Cessation
- 1995-03-15 ES ES95301727T patent/ES2116681T3/es not_active Expired - Lifetime
- 1995-03-15 TW TW084102465A patent/TW309426B/zh active
- 1995-03-15 EP EP95301727A patent/EP0686393B1/en not_active Expired - Lifetime
- 1995-03-16 CA CA002144810A patent/CA2144810A1/en not_active Abandoned
- 1995-03-17 KR KR1019950005633A patent/KR100338053B1/ko not_active Expired - Fee Related
- 1995-03-17 CN CN95103537A patent/CN1126072A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE166227T1 (de) | 1998-06-15 |
| EP0686393A1 (en) | 1995-12-13 |
| TW309426B (enExample) | 1997-07-01 |
| DE69502539T2 (de) | 1998-10-01 |
| KR950031062A (ko) | 1995-12-18 |
| KR100338053B1 (ko) | 2002-11-23 |
| US5652272A (en) | 1997-07-29 |
| CA2144810A1 (en) | 1995-09-19 |
| DE69502539D1 (de) | 1998-06-25 |
| ES2116681T3 (es) | 1998-07-16 |
| EP0686393B1 (en) | 1998-05-20 |
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| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Co-applicant after: MITSUBISHI CHEMICAL Corp. |
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| COR | Change of bibliographic data |
Free format text: CORRECT: CO-APPLICANT TO: MITSUBISHI CHEMICAL CO., LTD. |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |