CN112567036A - 用于基因编辑的修饰的向导rna - Google Patents

用于基因编辑的修饰的向导rna Download PDF

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CN112567036A
CN112567036A CN201980052704.4A CN201980052704A CN112567036A CN 112567036 A CN112567036 A CN 112567036A CN 201980052704 A CN201980052704 A CN 201980052704A CN 112567036 A CN112567036 A CN 112567036A
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nucleotides
modification
grna
nucleotide
modifications
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A·M·R·史密斯
S·亚历山大
D·布朗
R·布朗
A·兰巴
R·莱斯卡博
R·M·莱斯卡博
R·帕尔马
M·罗伊
P·萨勒诺
J·L·塞泽
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Intellia Therapeutics Inc
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Intellia Therapeutics Inc
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CN201980052704.4A 2018-06-08 2019-06-07 用于基因编辑的修饰的向导rna Pending CN112567036A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862682838P 2018-06-08 2018-06-08
US201862682820P 2018-06-08 2018-06-08
US62/682,820 2018-06-08
US62/682,838 2018-06-08
PCT/US2019/036160 WO2019237069A1 (en) 2018-06-08 2019-06-07 Modified guide rnas for gene editing

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CN112567036A true CN112567036A (zh) 2021-03-26

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US (1) US20210087568A1 (https=)
EP (1) EP3802828A4 (https=)
JP (2) JP7832761B2 (https=)
KR (2) KR102919364B1 (https=)
CN (1) CN112567036A (https=)
AU (2) AU2019282824C1 (https=)
BR (1) BR112020024731A2 (https=)
CA (1) CA3102950A1 (https=)
CO (1) CO2021000051A2 (https=)
IL (2) IL278822B1 (https=)
MX (2) MX2020013293A (https=)
PH (1) PH12020552100A1 (https=)
SA (1) SA520420729B1 (https=)
SG (1) SG11202011539VA (https=)
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WO2025007951A1 (zh) * 2023-07-06 2025-01-09 上海交通大学 一种靶向ttr的sacas9 sgrna及其修饰方式

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