CN1125602A - "Gongxuiting" instant preparation - Google Patents

Abstract

The medicine for curing abnormal metrorrhagia with high curative effect and no toxic by-effect is prepared from 11 Chinese-medicinal materials such as astragalus root, cimicifuga rhizome, pilose asiabell root, motherwort, cat-tail pollen, etc through breaking, roasting fossil fragment and oyster shell, treating lucid ligustrum fruit with yellow wine, mixing, decoction in water, addition of granular sugar, preparing extract, drying and granulating.

Description

" Gongxuiting " instant preparation

The invention belongs to the pharmaceutical products field, particularly relate to a kind of medicine of the women of treatment official blood.

At present, the undesired metrorrhagia of treatment women, the general dilatation and curettage method that adopts, however operation is comparatively complicated, poor effect, another kind method is medicine---the Herba Clinopodii Tabellae of the common treatment metrorrhagia that arrives on the market, and it is to use the Chinese medicine Herba Clinopodii, single medicinal material extracts the tablet of being processed into, and major function is cooling blood for hemostasis.

The objective of the invention is to, carry a kind of invigorating the spleen and replenishing QI blood that has, at the added time removing blood stasis, the elder generation that utilizes the plurality of Chinese preparation is based on the plug flow that takes stopgap measures, and official's blood that can also reach treating both the principal and secondary aspects of a disease stops electuary.

In order to achieve the above object, solution of the present invention is based on Chinese medicine to metrorrhagia, the traditional Chinese medical science is called " metrorrhagia ", comprise by inflammation, tumor, puerperal or metrorrhagia that post-abortion, organic disease such as subinvolution of uterus caused, also comprise by hormonal balance and lacking of proper care, the metrorrhagia that functional disorders such as ovarian hypofunction cause from motherland's medical treasure-house, filters out: the electuary that the proved recipe of classic prescriptions " BUZHONG YIQI TANG " plus-minus treatment official blood develops.

The present invention is formulated by following component, and its constituent content is (weight %): the Radix Astragali 18.2; Rhizoma Cimicifugae 5.5; Radix Codonopsis 5.5; Herba Leonuri 18.2; Pollen Typhae 5.5; Fructus Aurantii 5.5; Radix Angelicae Sinensis 5.5; Os Draconis 10.8; Concha Ostreae 10.8; Fructus Ligustri Lucidi 7.3; Herba Ecliptae 7.2.

The production method that official's blood of the present invention stops electuary is: a, above-mentioned 11 kinds of Chinese medicines choosing is clean, give as one thinks fit cataclasm, Os Draconis, oyster calcining, Fructus Ligustri Lucidi adds 20% yellow wine processed with wine, after the stir-fry of 10% Testa Tritici,, add 8 times of water gagings and decocted 1.5 hours its mixing, filter, its filtrate is placed, again its medicinal residues are added 6 times of water gagings and decocted 1 hour, refilter, medicinal residues are steamed secondary filtrate after abandoning, place in the concentration tank and be concentrated into the extractum that proportion is 1.36～1.38 (50 ℃ of thermit powders);

B, Saccharum Sinensis Roxb. select clean, and drying is 2 hours under 80 ℃ of conditions of temperature, pulverizes 60 mesh sieves;

C, get 1 part of extractum; add 2.4 parts in Saccharum Sinensis Roxb. powder; 0.8 part in dextrin, mixing and stirring is granulated with granulation machine; by 12 mesh sieves; cool slightly back is to be dried to moisture content≤5% under 80 ℃ of conditions with the wet granulate of tying of 10 mesh sieves in temperature, remove fine powder with 40 mesh sieves after; be installed on packing in the granule racking machine, every packed amount is 10 grams.

Official's blood of the present invention stops electuary to have advantage and be: (1) official's blood stops electuary decoction is made electuary, has kept the former decoction fast characteristics of proving effective; (2) be convenient to take, preserve and carry; (3) do not contain any chemical drugs no side effects; (4) drug dose is big, is easy to absorb; Good effect.

The embodiment that official's blood of the present invention is stopped electuary describes in further detail below.

" Gongxuiting " instant preparation of the present invention is formulated by following component, and its constituent content is (weight %): Rhizoma Cimicifugae 5.5; The Radix Astragali 18.2; Radix Codonopsis 5.5; Herba Leonuri 18.2; Pollen Typhae 5.5; Fructus Aurantii 5.5; Radix Angelicae Sinensis 5.5; Os Draconis 10.8; Concha Ostreae 10.8; Fructus Ligustri Lucidi 7.3; Herba Ecliptae 7..

The production method that official's blood of the present invention stops electuary is: a, above-mentioned 11 kinds of Chinese medicines choosing is clean, give as one thinks fit cataclasm, Os Draconis, oyster calcining, Fructus Ligustri Lucidi adds 20% yellow wine processed with wine, after the stir-fry of 10% Testa Tritici,, add 8 times of water gagings and decocted 1.5 hours its mixing, filter, its filtrate is placed, again its medicinal residues are added 6 times of water gagings and decocted 1 hour, refilter, medicinal residues are steamed secondary filtrate after abandoning, place in the concentration tank and be concentrated into the extractum that proportion is 1.36～1.38 (50 ℃ of thermit powders);

B, Saccharum Sinensis Roxb. select clean, and drying is 2 hours under 80 ℃ of conditions of temperature, pulverizes 60 mesh sieves;

C, get 1 part of extractum; add 2.4 parts in Saccharum Sinensis Roxb. powder; 0.8 part in dextrin, mixing and stirring is granulated with granulation machine; by 12 mesh sieves; cool slightly back is to be dried to moisture content≤5% under 80 ℃ of conditions with the wet granulate of tying of 10 mesh sieves in temperature, remove fine powder with 40 mesh sieves after; be installed on packing in the granule racking machine, every packed amount is 10 grams.

The quality standard of " Gongxuiting " instant preparation of the present invention:

1, character: this product is a brown yellow granule, and it is sweet to distinguish the flavor of, little hardship.

2, differentiate: get this product 20 grams, add 50ml ethanol, dissolution filter, filtrate is shone following method test:

1. get filtrate 10ml and place evaporating dish, evaporate to dryness, residue add acetic anhydride 1ml, make it dissolving, add 1 in sulphuric acid, show pink, the purpling redness that continues, and it is green to become black dirt at last, puts under the uviol lamp and observes, and shows yellow-green fluorescence;

2. get filtrate 10ml, place evaporating dish, evaporate to dryness, residue add 1% hydrochloric acid makes it dissolving, filters, and filtrate is put in the test tube, adds 1-2 of bismuth potassium iodide test solutions, produces salmon precipitation;

3. get filtrate 10ml, add 2-3 of magnesium powder a little and hydrochloric acid, heating, dissolving shows cherry red.

3, check: moisture content should be in 5%, and other should meet the pertinent regulations (10 pages of 90 editions appendix of pharmacopeia) under the electuary item.

4, function and curing mainly: invigorating spleen and kidney, the dispelling hemostasis of becoming silted up.Be used for menorrhagia, non-menstrual phase is bled and various uterus abnormal bleeding disease.

5, usage and consumption: boiled water is taken after mixing it with water, one time 20 gram, three times on the one.

Be subjected to the trust of Heilongjiang Province Department of Public Health, gynecological of No.1 Hospital Attached to Harbin Medical Univ., No.1 Hospital, Harbin City gynecological and Harbin City hospital for gynaecology and obstetrics, official's blood with the our factory development stops the method for administration of electuary according to unified regulation, observed content and criterion of therapeutical effect have been carried out 300 routine clinical observations, anovulatory dysfunctional uterine hemorrhage 157 examples among the 300 routine patients, subinvolution 9 examples behind hemorrhage 50 examples of band, the term birth, subinvolution 6 examples, artificial abortion's postoperative hemorrhage 18 examples, hysteromyoma 45 examples, other undesired metrorrhagia 15 examples after the cesarean.Method of administration: with ten days be a course of treatment, take medicine every day three times, take medicine one bag at every turn, use warm boiled water, take medicine altogether three courses of treatment (one month by a definite date), produce effects 112 examples in treating 300 routine patients, effective 161 examples, invalid 27 examples, total effective rate is 91.0%.

Claims (3)

1, a kind of " Gongxuiting " instant preparation is formed by multiple prepared from traditional Chinese medicines, it is characterized in that: its constituent content is (weight %).

The Radix Astragali 18.2%

Rhizoma Cimicifugae 5.5%

Radix Codonopsis 5.5%

Herba Leonuri 18.2%

Pollen Typhae 5.5%

Fructus Aurantii 5.5%

Radix Angelicae Sinensis 5.5%

Os Draconis 10.8%

Concha Ostreae 10.8%

Fructus Ligustri Lucidi 7.3%

Herba Ecliptae 7.2%

2, a kind of product processes that stops electuary according to the described official's blood of claim 1, it is characterized in that: a, above-mentioned 11 kinds of Chinese medicines choosing is clean, give particle as one thinks fit, Os Draconis, oyster calcining, Fructus Ligustri Lucidi adds 20% yellow wine processed with wine, after the stir-fry of 10% Testa Tritici, with its mixing, add 8 times of water gagings and decocted 1.5 hours, filter, its filtrate is placed, again its medicinal residues being added 6 times of water gagings decocted 1 hour, refilter, steam secondary filtrate after medicinal residues are abandoned, placing and concentrating proportion in the concentration tank is the extractum of 1.36～1.38 (50 ℃ of thermit powders);

B, Saccharum Sinensis Roxb. choosing under 80 ℃ of conditions of temperature, dry 2 hours, were pulverized 60 mesh sieves only;

C, get 1 part of extractum; add 2.4 parts in Saccharum Sinensis Roxb. powder; 0.8 part in dextrin, mixing and stirring is granulated with granulation machine; by 12 mesh sieves; cool slightly back is to be dried to moisture content≤5% under 80 ℃ of conditions with the wet granulate of tying of 10 mesh sieves in temperature, remove fine powder with 40 mesh sieves after; be installed on packing in the granule racking machine, every packed amount is 10 grams.

3, stop the production method of electuary by the described official's blood of claim 2, it is characterized in that: the moisture content of said Saccharum Sinensis Roxb.≤1%.