CN101637553A - Chinese medicinal composition for treating hysteromyoma and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese medicinal composition for treating hysteromyoma and a preparation method thereof. The Chinese medicinal composition comprises mongolian dandelion herb, common selfheal fruit-spike, cassia twig, motherwort herb, suberect spatholobus stem, yam, rhizoma corydalis, safflower, costustoot, weeping forsythia capsule and red peony root. The Chinese medicinal plants are extracted and concentrated respectively according to proportion, and are mixed into capsules and tablets according to different characteristics of each Chinese medicament. The medicament has the functions of activating blood and promoting menstruation, invigorating the vital energy and nourishing the blood, and removing blood stasis and dredging collaterals, and has remarkable curative effect in treating the hysteromyoma.

Description

A kind of Chinese medicine composition that is used for the treatment of hysteromyoma and preparation method thereof

Technical field

The invention belongs to the Chinese medicine preparation technical field, relate to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition that is used for the treatment of hysteromyoma and preparation method thereof.

Technical background

Hysteromyoma is the modal benign tumor of female reproductive system, and 30-50 year women sickness rate height finds that through autopsy data the sickness rate of hysteromyoma is about 20% more than 35 years old.The cause of disease of primary disease and pathogenesis are still very indefinite at present, clinical visible menorrhagia, and menostaxis, the cycle shortens, and can cause anemia, dysmenorrhea, leukorrhagia increases, and diseases such as infertile or miscarriage have a strong impact on patient's child-bearing health and quality of life.The tradition Chinese medicine is from organic conception, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, and in conjunction with women's periodic regularity, multipath, multi-angle treatment hysteromyoma has been obtained the experience for the treatment of preferably and achievement in research.

The main pathogenesis of primary disease is that QI-blood circulation is not smooth, and local QI and blood retardance is jammed.With the passing of time the imbalance of internal organs meridian function ties poly-addiction.Its main paathogenic factor has the stagnation of QI, blood stasis, phlegm-damp and damp and hot.Xia Chen etc. four think that hysteromyoma belongs to the burnt channels of expectorant dysentery, be by insufficiency of the spleen, suffer from a deficiency of the kidney, stagnation of liver-QI causes water damp-phlegm drink knot poly-,, hands over and hinders in the uterus in part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels channels with the passages through which vital energy circulates multiple abscess, condenses into tumor.Ceng Feiying draws and thinks hysteromyoma because deficiency of vital energy fortune blood is unable, blood-stasis internal-depression; The deficiency of vital energy is difficult transmitting and distributing the fluids, and water gathers into expectorant, and phlegm and blood stasis forms due to the abdominal mass abdominal mass.Xu Quanxiang discovery feelings will factor is occupied critical positions in the morbidity of hysteromyoma.Qi Nan etc. point out that " interior warp " contained stony mass of uterus is many and in utero form due to the caking because of cold coagulation, blood stasis stay to terminate in that stony mass of uterus promptly comprises the gynecological's abdominal mass abdominal mass disease based on hysteromyoma.

Hysteromyoma is a kind of substantive benign tumor of being mixed and being formed by outgrowth uterine smooth muscle cell and small amount of fibers connective tissue, and its standard name should be leiomyoma of uterus, is called for short hysteromyoma.Belonging to " abdominal mass disease ", " stony mass of uterus " or " menorrhagia ", " metrorrhagia " categories of etc.ing of Chinese medicine, is the common benign tumors of female sex organs, and pilosity is born in middle-aged women, occurs in 41-50 year at most, accounts for 50%, and next is in 31-40 year; 21-30 year and 50-60 the year rare generation, seldom take place below 20 years old and more than 60 years old.Many in recent years doctors inquire into method, the especially Chinese medicine of treatment primary disease.

Summary of the invention

The object of the invention is to provide a kind of Chinese medicine composition that is used for the treatment of hysteromyoma and preparation method thereof, to improve such sick medication environment, in the hope of alleviating the slight illness of female patient.

Be achieved through the following technical solutions order of the present invention:

1, the present invention is made by the following weight proportion raw material:

Herba Taraxaci 70-140 part Spica Prunellae 30-100 part Ramulus Cinnamomi 50-90 part

Herba Leonuri 50-90 part Caulis Spatholobi 30-100 part Rhizoma Dioscoreae 40-70 part

Rhizoma Corydalis 50-90 part Flos Carthami 50-90 part Radix Aucklandiae 40-70 part

Fructus Forsythiae 70-140 part Radix Paeoniae Rubra 30-100 part

2, each raw material weight proportioning of the best of the present invention's prescription is:

65 parts of 95 parts of Ramulus Cinnamomi of 120 parts of Spica Prunellaes of Herba Taraxaci

50 parts of 95 portions of Rhizoma Dioscoreaes of 65 portions of Caulis Spatholobis of Herba Leonuri

50 parts of 65 parts of Radix Aucklandiae of 65 parts of Flos Carthamis of Rhizoma Corydalis

95 parts of 120 parts of Radix Paeoniae Rubra of Fructus Forsythiae

3, preparation method:

(1) get Flos Carthami, the Radix Aucklandiae, water vapour distillation volatile oil is collected volatile oil, and aqueous solution and medicinal residues after the distillation are standby;

(2) get Ramulus Cinnamomi, Rhizoma Corydalis, be ground into coarse powder, mixed, with 75% ethanol of 6～10 times of medical material amounts, heating in water bath reflux, extract, 2～4 times each 1～2 hour, is collected alcohol extract, gradation is filtered, and merging filtrate and 50 ℃ of decompression recycling ethanol to relative densities are 1.16～1.22 clear paste, and be standby;

(3) get aqueous solution and medicinal residues after (1) distillation, add totally seven flavors such as all the other Herba Taraxacis, Spica Prunellae, mixed, add an amount of water again, decocts 3 times, decocted respectively 2,1,1 hours, merge decocting liquid, filtration.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 50～60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the clear paste that relative density is 1.23-1.29 (60 ℃), and is standby;

(4) above-mentioned two clear paste mixing is stirred evenly, 70 ℃ of drying under reduced pressure are ground into fine powder, behind technological forming, spray into volatile oil, make capsule or compacting in flakes, and coating promptly.

The invention discloses a kind of Chinese medicine composition that is used for the treatment of hysteromyoma and preparation method thereof, it by Herba Taraxaci, Spica Prunellae etc. totally ten simply Chinese crude drug form, according to the different qualities of every flavor Chinese medicine, in proportion, be mixed and made into capsule and tablet after extracting respectively, concentrating.Medicine of the present invention has the effect of promoting blood circulation to restore menstrual flow, benefiting qi and nourishing blood, clots absorbing collateral dredging, and the treatment of hysteromyoma is had significant curative effect.

The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.

The specific embodiment

Embodiment 1:

Adopt following prescription:

Herba Taraxaci 70g Spica Prunellae 30g Ramulus Cinnamomi 50g

Herba Leonuri 50g Caulis Spatholobi 30g Rhizoma Dioscoreae 40g

Rhizoma Corydalis 50g Flos Carthami 50g Radix Aucklandiae 40g

Fructus Forsythiae 70g Radix Paeoniae Rubra 30g

Preparation method:

(1) get Flos Carthami 50g, Radix Aucklandiae 40g, water vapour distillation volatile oil is collected volatile oil, and aqueous solution and medicinal residues after the distillation are standby;

(2) get Ramulus Cinnamomi, each 50g of Rhizoma Corydalis, be ground into coarse powder, mixed, with 75% ethanol of 8 times of medical material amounts, heating in water bath reflux, extract, 3 times each 1 hour, is collected alcohol extract, gradation is filtered, and merging filtrate and 50 ℃ of decompression recycling ethanol to relative densities are 1.21 clear paste, and be standby;

(3) get aqueous solution and medicinal residues after (1) distillation, add totally seven flavors such as all the other Herba Taraxacis, Spica Prunellae, mixed, add an amount of water again, decocts 3 times, decocted respectively 2,1,1 hours, merge decocting liquid, filtration.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 50% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the clear paste that relative density is 1.27 (60 ℃), and is standby;

(4) above-mentioned two clear paste mixing is stirred evenly, 70 ℃ of drying under reduced pressure are ground into fine powder, add the about 90g of starch, spray into volatile oil, and mixing is directly encapsulated, promptly.

Embodiment 2:

Adopt following prescription:

Herba Taraxaci 120g Spica Prunellae 95g Ramulus Cinnamomi 65g

Herba Leonuri 65g Caulis Spatholobi 95g Rhizoma Dioscoreae 50g

Rhizoma Corydalis 65g Flos Carthami 65g Radix Aucklandiae 50g

Fructus Forsythiae 120g Radix Paeoniae Rubra 95g

Preparation method:

(1) get Flos Carthami 65g, Radix Aucklandiae 50g, water vapour distillation volatile oil is collected volatile oil, and aqueous solution and medicinal residues after the distillation are standby;

(2) get Ramulus Cinnamomi, each 65g of Rhizoma Corydalis, be ground into coarse powder, mixed, with 75% ethanol of 10 times of medical material amounts, heating in water bath reflux, extract, 4 times each 1 hour, is collected alcohol extract, gradation is filtered, and merging filtrate and 50 ℃ of decompression recycling ethanol to relative densities are 1.18 clear paste, and be standby;

(3) get aqueous solution and medicinal residues after (1) distillation, add totally seven flavors such as all the other Herba Taraxacis, Spica Prunellae, mixed, add an amount of water again, decocts 3 times, decocted respectively 2,1,1 hours, merge decocting liquid, filtration.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the clear paste that relative density is 1.25 (60 ℃), and is standby;

(4) above-mentioned two clear paste mixing is stirred evenly, 70 ℃ of drying under reduced pressure are ground into fine powder, add the about 150g of starch, and the about 60g of dextrin uses 90% alcohol granulation, spray into volatile oil after the dry anti-cold, and compacting is in blocks, sugar coating, promptly.

Claims (3)

1, a kind of Chinese medicine composition that is used for the treatment of hysteromyoma is characterized in that it is made by following raw material:

Herba Taraxaci 70-140 part Spica Prunellae 30-100 part Ramulus Cinnamomi 50-90 part

Herba Leonuri 50-90 part Caulis Spatholobi 30-100 part Rhizoma Dioscoreae 40-70 part

Rhizoma Corydalis 50-90 part Flos Carthami 50-90 part Radix Aucklandiae 40-70 part

Fructus Forsythiae 70-140 part Radix Paeoniae Rubra 30-100 part.

2, a kind of Chinese medicine composition that is used for the treatment of hysteromyoma as claimed in claim 1 is characterized in that the proportioning of each component is:

65 parts of 95 parts of Ramulus Cinnamomi of 120 parts of Spica Prunellaes of Herba Taraxaci

50 parts of 95 portions of Rhizoma Dioscoreaes of 65 portions of Caulis Spatholobis of Herba Leonuri

50 parts of 65 parts of Radix Aucklandiae of 65 parts of Flos Carthamis of Rhizoma Corydalis

95 parts of 120 parts of Radix Paeoniae Rubra of Fructus Forsythiae.

3, as the described a kind of Chinese medicine composition that is used for the treatment of hysteromyoma of claim 1-2, it is characterized in that the preparation method of this Chinese medicine composition is:

(1) get Flos Carthami, the Radix Aucklandiae, water vapour distillation volatile oil is collected volatile oil, and aqueous solution and medicinal residues after the distillation are standby;

(2) get Ramulus Cinnamomi, Rhizoma Corydalis, be ground into coarse powder, mixed, with 75% ethanol of 6～10 times of medical material amounts, heating in water bath reflux, extract, 2～4 times each 1～2 hour, is collected alcohol extract, gradation is filtered, and merging filtrate and 50 ℃ of decompression recycling ethanol to relative densities are 1.16～1.22 clear paste, and be standby;

(3) get aqueous solution and medicinal residues after (1) distillation, add totally seven flavors such as all the other Herba Taraxacis, Spica Prunellae, mixed, add an amount of water again, decocts 3 times, decocted respectively 2,1,1 hours, merge decocting liquid, filtration.Filtrate water-bath solvent flashing is to an amount of, adds ethanol and makes and contain the alcohol amount and reach 50～60% (V/V), and liquid was left standstill in cold preservation.Get supernatant, reclaim under reduced pressure is to nothing alcohol flavor, and water-bath is concentrated into the clear paste that relative density is 1.23-1.29 (60 ℃), and is standby;

(4) above-mentioned two clear paste mixing is stirred evenly, 70 ℃ of drying under reduced pressure are ground into fine powder, behind technological forming, spray into volatile oil, make capsule or compacting in flakes, and coating promptly.