CN102370726A - Compound Chinese medicinal preparation for treating chloasma and preparation method thereof - Google Patents
Compound Chinese medicinal preparation for treating chloasma and preparation method thereof Download PDFInfo
- Publication number
- CN102370726A CN102370726A CN2011103642181A CN201110364218A CN102370726A CN 102370726 A CN102370726 A CN 102370726A CN 2011103642181 A CN2011103642181 A CN 2011103642181A CN 201110364218 A CN201110364218 A CN 201110364218A CN 102370726 A CN102370726 A CN 102370726A
- Authority
- CN
- China
- Prior art keywords
- percent
- radix
- chinese medicinal
- chloasma
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention relates to a compound Chinese medicinal preparation for treating chloasma. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials in weight by percentage: 5-7 percent of root of Chinese thorowax, 13-17 percent of tuckahoe, 8-12 percent of white paeony root, 8-12 percent of angelica, 8-12 percent of bighead atractylodes rhizome, 13-17 percent of root of red-rooted salvia, 8-12 percent of safflower, 5-7 percent of stiff silkworm and 8-12 percent of angelica root. A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the 9 medicinal materials; mixing in proportion; adding water in an amount which is 6-8 times the total weight of the medicinal materials or ethanol in an amount which is 70 percent of the volume ratio to decoct for 3 times, 50 minutes each time; combining decoction for 3 times; filtering; and concentrating to obtain liquid extract with specific gravity of 1.13 at the temperature of 60 DEG C. By adopting the conventional reparation process, the preparation can be prepared into any one pharmaceutically said formulation, such as tablets, capsules, granules, oral liquid, pills and syrup. The compound Chinese medicinal preparation for treating the chloasma prepared by the invention has the advantages of obvious curative effect, simple administration mode and no adverse effect.
Description
Technical field
The present invention relates to a kind of compound Chinese medicinal preparation of treating chloasma and preparation method thereof, belong to field of traditional Chinese.
Background technology
Chloasma is that dermal melanin increases and a kind of face of forming is brown or black pigment calmness property discosmetic dermatosis, is one of department of dermatologry difficult and complicated illness.
It is relevant that modern medicine thinks that pathogeny and the intravital Progesterone and the estrogen secretion of chloasma increase the chafe melanocyte, in addition with ultraviolet radiation, make apply some make up, factors such as medicine (like contraceptive, chlorpromazine), gestation, disease (like hepatitis, tumor, hyperthyroidism, gynaecopathia) and heredity are relevant.The traditional Chinese medical science is referred to as meaning " dusty face ", " chloasma hepaticum ", " chloasma ", be commonly called as " cyasma " etc., and its pathogeny is: stagnation of QI due to depression of the liver, blood stasis are in face; Insufficiency of the spleen can not to change spermatogenesis little, and QI and blood deficiency, skin lose in honor and support; Deficiency of kidney-QI can not be made fire, accumulates in the deficiency-heat, and pent-up is not loose, and hinders due to the skin.
The chloasma course of disease is long, and obstinate refractory needs the patient to adhere to that for a long time treatment just can take effect, and the instrument treatment procedure is complicated, can not life-time service, and the patient accepts misery, and curative effect waits shortcoming repeatedly; And herbal treatment can with medicine process the patient can oneself be in the life-time service and the dosage form easy to carry of going out, and use no pain, the patient takes like a shot, and can help the patient to adhere to treatment accomplishing enough courses of treatment, thereby obtains satisfactory effect.
Summary of the invention
The object of the present invention is to provide a kind of Chinese traditional compound medicine of treating chloasma and preparation method thereof.
The present invention provides the compound Chinese medicinal preparation of a kind of Radix Bupleuri, Poria, the Radix Paeoniae Alba, Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Flos Carthami, Bombyx Batryticatus, Radix Angelicae Dahuricae compatibility to be used to treat chloasma, and administering mode is simple, and is evident in efficacy, has no adverse reaction, and the patient uses no pain.
Technical scheme of the present invention is following:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 5-7, Poria 13-17, Radix Paeoniae Alba 8-12, Radix Angelicae Sinensis 8-12, Rhizoma Atractylodis Macrocephalae 8-12, Radix Salviae Miltiorrhizae 13-17, Flos Carthami 8-12, Bombyx Batryticatus 5-7, Radix Angelicae Dahuricae 8-12.
Wherein method for preparing is that above-mentioned 9 flavor medical materials are cleaned, and proportional mixing, the 6-8 that adds medical material gross weight water or volume ratio doubly is that 70% ethanol decocts 3 times; Each 50 minutes hours, merge 3 times decoction liquor, filter; And concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃, adopts conventional preparation technology; Chinese medicine preparation of the present invention can be made into said dosage form on any pharmaceutics, like tablet, capsule, granule, oral liquid, pill, syrup.
Radix Bupleuri depressed liver-energy dispersing and QI regulating resolving depression in the present invention's prescription; Poria inducing diuresis to remove edema, invigorating spleen to remove dampness; Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver; Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Flos Carthami blood circulation promoting and blood stasis dispelling, strike off dirty, eliminating dampness by diuresis disappear stagnant, brightening, dispelling spots, dispelling, nourish blood preserve youthful looks, sliding flesh pool face; Rhizoma Atractylodis Macrocephalae circulation of qi promoting spleen invigorating; The Bombyx Batryticatus and the Radix Angelicae Dahuricae improve blee, the longue skin moistening, and stain clearing and face beautifying, all medicines share the effect of playing whitening and speckle dispelling, skin care skin moistening altogether.Therefore curative effect of the present invention is good, and administering mode is simple, has no adverse reaction.
Specific embodiment
Embodiment 1:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 5, Poria 13, the Radix Paeoniae Alba 8, Radix Angelicae Sinensis 8, the Rhizoma Atractylodis Macrocephalae 8, Radix Salviae Miltiorrhizae 13, Flos Carthami 8, Bombyx Batryticatus 5, the Radix Angelicae Dahuricae 8.
Wherein method for preparing is that above-mentioned 9 flavor medical materials are cleaned, proportional mixing, and 6 times the decocting that adds the medical material gross weight boils 3 times, and each 50 minutes hours, merge 3 times decoction liquor, to filter, and concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
Embodiment 2:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 6, Poria 15, the Radix Paeoniae Alba 10, Radix Angelicae Sinensis 10, the Rhizoma Atractylodis Macrocephalae 10, Radix Salviae Miltiorrhizae 15, Flos Carthami 10, Bombyx Batryticatus 6, the Radix Angelicae Dahuricae 10.
All the other are with embodiment 1.
Embodiment 3:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 7, Poria 17, the Radix Paeoniae Alba 12, Radix Angelicae Sinensis 12, the Rhizoma Atractylodis Macrocephalae 12, Radix Salviae Miltiorrhizae 17, Flos Carthami 12, Bombyx Batryticatus 7, the Radix Angelicae Dahuricae 12.
Wherein method for preparing is that above-mentioned 9 flavor medical materials are cleaned, proportional mixing, and 6 times of volume ratios that add the medical material gross weight are that 70% ethanol decocts 3 times, each 50 minutes hours, merges 3 times decoction liquor, filter, and concentrated, proportion is 1.13 fluid extract when obtaining 60 ℃.
Embodiment 4:
A kind of Chinese traditional compound medicine of treating chloasma, wherein method for preparing is the medical material in the prescription to be cleaned proportional mixing; 7 times of volume ratios that add the medical material gross weight are that 70% ethanol 7 decocts 3 times; Each 50 minutes hours, merge 3 times decoction liquor, filter; And concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
All the other are with embodiment 1.
Embodiment 5:
A kind of Chinese traditional compound medicine of treating chloasma, wherein method for preparing is the medical material in the prescription to be cleaned proportional mixing; 7 times the decocting that adds the medical material gross weight boils 3 times, each 50 minutes hours, merges 3 times decoction liquor; Filter, and concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
All the other are with embodiment 2.
Embodiment 6:
A kind of Chinese traditional compound medicine of treating chloasma, wherein method for preparing is the medical material in the prescription to be cleaned proportional mixing; 7 times the decocting that adds the medical material gross weight boils 3 times, each 50 minutes hours, merges 3 times decoction liquor; Filter, and concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
All the other are with embodiment 3.
Embodiment 7:
A kind of Chinese traditional compound medicine of treating chloasma, wherein method for preparing is the medical material in the prescription to be cleaned proportional mixing; 8 times of volume ratios that add the medical material gross weight are that 70% ethanol decocts 3 times; Each 50 minutes hours, merge 3 times decoction liquor, filter; And concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
All the other are with embodiment 2.
Embodiment 8:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 10, Poria 20, the Radix Paeoniae Alba 15, Radix Angelicae Sinensis 15, the Rhizoma Atractylodis Macrocephalae 8, Radix Salviae Miltiorrhizae 10, Flos Carthami 6, Bombyx Batryticatus 3, the Radix Angelicae Dahuricae 5.
Wherein method for preparing is that the medical material in the prescription is cleaned, proportional mixing, and 8 times the decocting that adds the medical material gross weight boils 3 times, and each 50 minutes hours, merge 3 times decoction liquor, to filter, and concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
Embodiment 9:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 3, Poria 10, the Radix Paeoniae Alba 6, Radix Angelicae Sinensis 6, the Rhizoma Atractylodis Macrocephalae 13, Radix Salviae Miltiorrhizae 18, Flos Carthami 15, Bombyx Batryticatus 10, the Radix Angelicae Dahuricae 13.
Wherein method for preparing is that the medical material in the prescription is cleaned, proportional mixing, and 8 times of volume ratios that add the medical material gross weight are that 70% ethanol decocts 3 times, each 50 minutes hours, merges 3 times decoction liquor, filter, and concentrated, proportion is 1.13 fluid extract when obtaining 60 ℃.
Embodiment 10:
A kind of Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 4, Poria 18, the Radix Paeoniae Alba 7, Radix Angelicae Sinensis 12, the Rhizoma Atractylodis Macrocephalae 7, Radix Salviae Miltiorrhizae 18, Flos Carthami 7, Bombyx Batryticatus 8, the Radix Angelicae Dahuricae 7.
Wherein method for preparing is that above-mentioned 9 flavor medical materials are cleaned, proportional mixing, and 5 times the water 7 that adds the medical material gross weight decocts 3 times, and each 50 minutes hours, merge 3 times decoction liquor, to filter, and concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃.
Embodiment 11:
Be disclosed chloasma eliminating medicine in 00130136.6 the patent according to application number, comprise following raw material of Chinese medicine:
A side: Rhizoma Atractylodis Macrocephalae (parched) 20g, Poria 10g, Rhizoma Dioscoreae 20g, Semen Nelumbinis 10g, Radix Morindae Officinalis 15g, Semen Ginkgo 15g, Cortex Eucommiae 15g, Cortex Cinnamomi 10g, Endothelium Corneum Gigeriae Galli 10g, Ramulus Cinnamomi 15g, Radix Dipsaci 10g.
B side: Radix Angelicae Sinensis 20g, Radix Paeoniae Alba (parched) 15g, Colla Corii Asini 15g, Fructus Corni 15g, Radix Morindae Officinalis 20g, Rhizoma Dioscoreae 15g, Endothelium Corneum Gigeriae Galli 10g.
C side: Radix Angelicae Sinensis 20g, Radix Rehmanniae 10g, Semen Persicae 15g, Flos Carthami 25g, Radix Platycodonis 15g, Radix Paeoniae Rubra 15g, Radix Bupleuri 15g, Radix Cyathulae 10g, Rhizoma Chuanxiong 20g, Rhizoma Cyperi 15g, Radix Salviae Miltiorrhizae 20g.
A, B, C side are all respectively with being decocted in water for oral dose; Took before menstruation comes in 5-7 days A side, and B side takes to ischomenia in first day in menstruation, and C side is after ending and taking during this future.
Embodiment 12:
Prescription according to " the Shaanxi traditional Chinese medical science " 2000 the 21st disclosed treatment chloasma of volume the 3rd interim " JIAWEI XIAOYAO SAN treatment chloasma 50 examples " comprises following traditional Chinese medicine raw:
Radix Bupleuri, Radix Curcumae, Semen Persicae, Flos Carthami, the Radix Paeoniae Alba, from each lOg of art, Radix Angelicae Sinensis, each 12g of Poria, Radix Salviae Miltiorrhizae 20g, Herba Menthae 6g.Fry in shallow oil filtered juice 300ml, 2 sub-services sooner or later. 1 dose of every day.
Embodiment 13: adopt conventional preparation technology, Chinese medicine preparation of the present invention can be made into said dosage form on any pharmaceutics, like tablet, capsule, granule, oral liquid, pill, syrup.
All the other are with embodiment 1-10.
Embodiment 14: the fluid extract of the mix homogeneously that will be made by embodiment 1-10 concentrates, and according to the operational approach of conventional tablet, adds pharmaceutic adjuvant; With each component mix homogeneously, wet granulation sieves; Adopt conventional tablet preparation method tabletting to process tablet, wherein each components contents is following:
Composition weight (part)
Mixed flow extractum 50
Starch 25
Microcrystalline Cellulose 13
Pulvis Talci 12
Polyethylene Glycol 8
All the other are with embodiment 1-10.
Embodiment 15: the fluid extract of the mix homogeneously that will be made by embodiment 1-10 concentrates, and according to the operational approach of conventional capsule, adds pharmaceutic adjuvant; With each component mix homogeneously; Granulate, adopt conventional capsule preparation method to fill and process capsule, wherein each components contents is following:
Composition weight (part)
Mixed flow extractum 100
Pregelatinized Starch 27
Lactis Anhydrous 20
Microcrystalline Cellulose 16
Calcium hydrogen phosphate 6
All the other are with embodiment 1-10.
Embodiment 16: the fluid extract of the mix homogeneously that will be made by embodiment 1-10 concentrates, according to the operational approach of conventional oral liquid, ethanol precipitation 1-2 time; Filter, concentrate aqueous precipitation; Filter, add pharmaceutic adjuvant, filter; The packing sterilization adopts conventional oral liquid preparation method to prepare oral liquid, and wherein each components contents is following:
Composition weight (part)
Mixed flow extractum 100
Ethanol 168
Sucrose 72
Sodium carboxymethyl cellulose 13
Oleum menthae 5
Sorbic acid 3
All the other are with embodiment 1-10.
The effectiveness study experiment:
Patient's data:
Totally 364 routine patients are female patient, and the age is at 21-56 between year, average 38 years old; The course of disease is 6 months-10 years, average 5 years.The clinical diagnosis standard that all meets traditional Chinese medical science chloasma, no internal organs systemic disease and pigment obstacle disease, all patients all have and use all kinds of cosmetics histories, and once in the department of dermatologry treatment of repeatedly going to a doctor.364 routine patients are divided into 13 groups at random, and 1 group as matched group, organize as treatment for 12 groups, every group 28 example, 13 groups of ages, the course of disease and state of an illness relatively, there are no significant for difference (P>0. 05), has comparability.
Diagnostic criteria:
1, facial filbert to dark brown, well-defined patch, symmetry distributes usually, NIP performance and squama.
2, there is not obvious subjective symptoms.
3, the women is multiple, mainly occur in adolescence after.
4, the state of an illness can have seasonality, and the Chang Xiachong winter is light.
5, get rid of the pigmentation that other disease (like the brown cyan nevus of cheekbone portion, Rieh1 melanosis and pigment property actinic lichen planus etc.) causes.
Therapeutic Method:
Matched group external thousand white hydroquinone creams, are put on the skin in the affected part in right amount at morning and evening every day twice; With the prepared Chinese medical concrete of embodiment 1-10 10 times of dilute with waters by volume, give 10 groups of treatment groups oral respectively, each 100ml, every day 2 times sooner or later, remaining two groups of treatment groups are taken the herbal mixture that embodiment 11 and embodiment 12 make respectively; Treatment group and matched group continuous use 2 months.
Criterion of therapeutical effect:
The basic healing: naked eyes are looked the mottle area and are disappeared>90%, color disappears basically; Produce effects: naked eyes are looked the mottle area and are disappeared>60%, color is obviously thin out, shoal; Take a turn for the better: naked eyes are looked the mottle area and are disappeared>30%, color is thin out, shoal; Invalid: naked eyes are looked the mottle area and are disappeared that < 30%, change color is not obvious.
Table 1 is respectively organized curative effect relatively
2 routine local anaphylaxises appear in matched group in therapeutic process, any untoward reaction does not appear in the treatment group.
Can find out from the effectiveness study experiment; Curative effect of the present invention obviously is better than the external preparation of existing treatment chloasma, and is superior to the curative effect of the Chinese medicine medicine that similar prescription makes in the prior art, and is wherein best with the therapeutic effect of embodiment 5; Medication is simpler than external preparation again; Therefore the Chinese traditional compound medicine of the treatment chloasma that makes of the present invention is evident in efficacy, and administering mode is simple, has no adverse reaction.
Claims (5)
1. a Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 5-7, Poria 13-17, Radix Paeoniae Alba 8-12.
2. a Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 5-7, Poria 13-17, Radix Paeoniae Alba 8-12, Radix Angelicae Sinensis 8-12, Rhizoma Atractylodis Macrocephalae 8-12, Radix Salviae Miltiorrhizae 13-17, Flos Carthami 8-12, Bombyx Batryticatus 5-7, Radix Angelicae Dahuricae 8-12.
3. a Chinese traditional compound medicine of treating chloasma comprises the following weight Chinese medicinal raw materials: Radix Bupleuri 6, Poria 15, the Radix Paeoniae Alba 10, Radix Angelicae Sinensis 10, the Rhizoma Atractylodis Macrocephalae 10, Radix Salviae Miltiorrhizae 15, Flos Carthami 10, Bombyx Batryticatus 6, the Radix Angelicae Dahuricae 10.
4. like claim 2 or 3 said a kind of method for preparinies of treating the Chinese traditional compound medicine of chloasma, it is characterized by: 9 flavor medical materials are cleaned proportional mixing; The 6-8 that adds medical material gross weight water or volume ratio doubly is that 70% ethanol decocts 3 times, each 50 minutes hours, merges 3 times decoction liquor; Filter; And concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃, adopts conventional preparation technology; Chinese medicine preparation of the present invention can be made into said dosage form on any pharmaceutics, like tablet, capsule, granule, oral liquid, pill, syrup.
5. a kind of method for preparing of treating the Chinese traditional compound medicine of chloasma as claimed in claim 4 is characterized by: 9 flavor medical materials are cleaned proportional mixing; 7 times the decocting that adds the medical material gross weight boils 3 times, each 50 minutes hours, merges 3 times decoction liquor; Filter; And concentrate, proportion is 1.13 fluid extract when obtaining 60 ℃, adopts conventional preparation technology; Chinese medicine preparation of the present invention can be made into said dosage form on any pharmaceutics, like tablet, capsule, granule, oral liquid, pill, syrup.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110364218.1A CN102370726B (en) | 2011-11-17 | 2011-11-17 | A kind of compound Chinese medicinal preparation for the treatment of chloasma and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110364218.1A CN102370726B (en) | 2011-11-17 | 2011-11-17 | A kind of compound Chinese medicinal preparation for the treatment of chloasma and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102370726A true CN102370726A (en) | 2012-03-14 |
| CN102370726B CN102370726B (en) | 2016-05-25 |
Family
ID=45790310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110364218.1A Expired - Fee Related CN102370726B (en) | 2011-11-17 | 2011-11-17 | A kind of compound Chinese medicinal preparation for the treatment of chloasma and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102370726B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657745A (en) * | 2012-05-17 | 2012-09-12 | 双飞人制药（中国）有限公司 | Medicinal composition with effect of removing chloasma |
| CN103222655A (en) * | 2013-04-22 | 2013-07-31 | 河南省淼雨饮品股份有限公司 | Yellow spot-removing apple vinegar health-care beverage and preparation method thereof |
| CN105031333A (en) * | 2015-07-08 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Traditional Chinese medicine paste for treating chloasma and preparation method thereof |
| CN106729150A (en) * | 2017-01-19 | 2017-05-31 | 四川香龙丹医药科技有限公司 | A kind of pharmaceutical formulation of skin-whitening and speckle eliminating |
| CN108498569A (en) * | 2018-06-26 | 2018-09-07 | 宋智琦 | Treat the herbal mixture tincture of chloasma |
| CN111388616A (en) * | 2020-04-14 | 2020-07-10 | 梁恒星 | Vine flower medicine bath bag |
| CN112843155A (en) * | 2021-02-04 | 2021-05-28 | 建昌帮药业有限公司 | Composition suitable for puerpera and used for removing freckles and relieving lumbago |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153655A (en) * | 1996-08-19 | 1997-07-09 | 侯永康 | Chinese medicine prepn for balancing internal secretion |
| CN1739774A (en) * | 2004-08-06 | 2006-03-01 | 王继平 | Spot eliminating and youthful looks preserving capsule |
| CN101972459A (en) * | 2010-10-10 | 2011-02-16 | 杨万明 | Medicament for treating chloasma and preparation method thereof |
-
2011
- 2011-11-17 CN CN201110364218.1A patent/CN102370726B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1153655A (en) * | 1996-08-19 | 1997-07-09 | 侯永康 | Chinese medicine prepn for balancing internal secretion |
| CN1739774A (en) * | 2004-08-06 | 2006-03-01 | 王继平 | Spot eliminating and youthful looks preserving capsule |
| CN101972459A (en) * | 2010-10-10 | 2011-02-16 | 杨万明 | Medicament for treating chloasma and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 汪黔蜀: "消斑汤治疗黄褐斑36例疗效观察", 《云南中医学院学报》 * |
| 王耘: "加味逍遥散治疗黄褐斑50例", 《陕西中医》 * |
| 王耘: "加味逍遥散治疗黄褐斑50例", 《陕西中医》, vol. 21, no. 03, 31 December 2000 (2000-12-31), pages 117 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102657745A (en) * | 2012-05-17 | 2012-09-12 | 双飞人制药（中国）有限公司 | Medicinal composition with effect of removing chloasma |
| CN103222655A (en) * | 2013-04-22 | 2013-07-31 | 河南省淼雨饮品股份有限公司 | Yellow spot-removing apple vinegar health-care beverage and preparation method thereof |
| CN103222655B (en) * | 2013-04-22 | 2015-06-17 | 河南省淼雨饮品股份有限公司 | Yellow spot-removing apple vinegar health-care beverage and preparation method thereof |
| CN105031333A (en) * | 2015-07-08 | 2015-11-11 | 江苏奇力康皮肤药业有限公司 | Traditional Chinese medicine paste for treating chloasma and preparation method thereof |
| CN106729150A (en) * | 2017-01-19 | 2017-05-31 | 四川香龙丹医药科技有限公司 | A kind of pharmaceutical formulation of skin-whitening and speckle eliminating |
| CN108498569A (en) * | 2018-06-26 | 2018-09-07 | 宋智琦 | Treat the herbal mixture tincture of chloasma |
| CN111388616A (en) * | 2020-04-14 | 2020-07-10 | 梁恒星 | Vine flower medicine bath bag |
| CN112843155A (en) * | 2021-02-04 | 2021-05-28 | 建昌帮药业有限公司 | Composition suitable for puerpera and used for removing freckles and relieving lumbago |
| CN112843155B (en) * | 2021-02-04 | 2022-05-10 | 建昌帮药业有限公司 | Composition suitable for puerpera and used for removing freckles and relieving lumbago |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102370726B (en) | 2016-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102370726A (en) | Compound Chinese medicinal preparation for treating chloasma and preparation method thereof | |
| CN103341145B (en) | Traditional Chinese medicine for treating psoriasis and preparation method thereof | |
| CN102370949A (en) | Chinese medicinal compound preparation for treating cholecystitis and preparation method thereof | |
| CN103285310A (en) | Use of rhodiola rosea compound composition in preparing medicine for curing gastric ulcer | |
| CN103212021A (en) | Traditional Chinese medicine composition used for treating chloasma | |
| CN101396542A (en) | Traditional Chinese medicine formulation for treating gastrosis and preparation method thereof | |
| CN103356772B (en) | Medicament used for treating chloasma | |
| CN103638335B (en) | A kind of Chinese medicine for the treatment of refractory acne and preparation method thereof | |
| CN103656436A (en) | Traditional Chinese medicine dispersible tablet with functions of regulating menstruation and replenishing blood and preparation method of traditional Chinese medicine dispersible tablet | |
| CN102139034A (en) | Medicament for treating chloasma | |
| CN102552520B (en) | Blood circulation-promoting and pain-stopping medicament and preparation process and application thereof | |
| CN1351872A (en) | Chinese herbal medicine for curing comedo and acne | |
| CN102327395B (en) | Pharmaceutical composition for treating postpartum persistent lochia and preparation method thereof | |
| CN101543577A (en) | Traditional Chinese medicine composition for curing whelk and preparation method thereof | |
| CN105362920A (en) | Chinese proprietary medicine for treating chloasma | |
| CN103610796A (en) | Traditional Chinese medicinal composition for treating exfoliative inflammation of lips | |
| CN102018847A (en) | Chinese medicinal preparation for treating dysmenorrhea and postpartum blood stasis | |
| CN102579678B (en) | Medicinal composition for treating vitligo | |
| CN101991738A (en) | Traditional Chinese medicine preparation for treating dysmenorrhea | |
| CN1814125A (en) | Rehmannia-root preparation | |
| CN102370838B (en) | Kidney-invigorating and tendon-reinforcing double-phase capsule | |
| CN103230475B (en) | One treats psoriatic medicine | |
| CN102430026A (en) | Medicine for removing macula | |
| CN101391009A (en) | Medicine composition for treating diabetic nephropathy of deficiency of both qi and yin and accumulation of blood stasis and preparation method thereof | |
| CN101279069A (en) | Medicament composite for dredging channels and collaterals, and promoting blood-circulation and removing blood stasis, and method of preparing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160525 Termination date: 20171117 |