CN112535760A - Repair type medical cold compress dressing - Google Patents
Repair type medical cold compress dressing Download PDFInfo
- Publication number
- CN112535760A CN112535760A CN202011574947.5A CN202011574947A CN112535760A CN 112535760 A CN112535760 A CN 112535760A CN 202011574947 A CN202011574947 A CN 202011574947A CN 112535760 A CN112535760 A CN 112535760A
- Authority
- CN
- China
- Prior art keywords
- extract
- percent
- cold compress
- medical cold
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
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Abstract
The invention relates to a repair type medical cold compress dressing which comprises the following substances: milk protein, serine, folium artemisiae argyi extract, apple fruit extract, perilla extract, resveratrol, sodium hyaluronate, motherwort extract, pepper seed extract, hesperidin, perilla seed oil, walnut oil, olive oil, borneol, an emulsifier, polyglycerol-6 esters, ginger root oil, glutathione, a plant extract and water. The repairing medical cold compress dressing has the functions of balancing internal secretion and improving immunity, is rich in extracts of effective components such as resveratrol, folium artemisiae argyi, sodium hyaluronate, serine, motherwort herb, pepper seed, purple perilla, hesperidin and the like, can effectively promote the lipolysis process and metabolism, further eliminates orange peel tissues, is matched with effective plant extracts, activates a blood circulation system in a body and has the effects of diminishing inflammation and relieving pain, does not bring pain to skin when in use, and is high in mildness.
Description
Technical Field
The invention relates to the technical field of medical dressings, in particular to a repair type medical cold compress dressing.
Background
Skin is an important barrier for the human body against external damage. In daily life, skin injuries are common, such as skin abrasion, contusion, slight cut, slight scald, burn, sunburn, slight medical and cosmetic operation and other accidents or skin local superficial wound injuries caused by diseases, after the skin barrier is injured, the resistance is reduced, external bacteria are easily infected, and the phenomena of small amount of bleeding, tissue fluid exudation and the like are caused when the skin barrier of inflammation reactions such as pruritus, red swelling, stabbing pain and other parts is injured. Therefore, the medical dressing is usually applied to repair and nursing of skin barriers, and can play important roles in protecting wounds, preventing infection, repairing, promoting wound healing and the like. However, the existing medical dressing can not effectively promote the lipolysis process and the metabolism.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a repair type medical cold compress dressing which can permeate into the human body through skin and glands to play a role in repairing cells, supplementing energy and dredging channels and collaterals.
The technical purpose of the invention is realized by the following technical scheme: the repair type medical cold compress dressing comprises the following substances in percentage by mass:
milk protein: 5.0 to 10.0 percent;
serine: 1.0-2.5%;
the folium artemisiae argyi extract: 1.0 to 3.5 percent;
apple fruit extract: 2.0-4.0%;
and (3) perilla extract: 1.0-3.0%;
resveratrol: 3.0 to 5.0 percent;
sodium hyaluronate: 4.0 to 6.0 percent;
motherwort extract: 1.0-3.0%;
pepper seed extract: 1.0-3.0%;
hesperidin: 2.0 to 3.0 percent;
purple perilla seed oil: 1.0 to 3.5 percent;
walnut oil: 2.0 to 3.0 percent;
olive oil: 1.0-3.0%;
borneol: 0.2 to 0.5 percent;
emulsifier: 0.05 to 1.5 percent;
polyglycerol-6 esters: 0.05 to 1.0 percent
Ginger root oil: 1.0-3.0%;
glutathione: 1.0-3.0%;
plant extracts: 10.5 to 28.0 percent;
water: and (4) the balance.
Further, the plant extract comprises lithospermum extract, ginseng extract, peony root bark extract, notopterygium root extract and ginger root extract; the contents of the lithospermum extract, the ginseng extract, the peony root bark extract, the notopterygium root extract and the ginger root extract are respectively 2.0-4.0%, 2.0-5.0%, 1.0-3.0%, 4.0-6.0% and 2.0-4.0%.
Further, the plant extract also comprises oat extract; the content of the oat extract is 1.0-3.0%.
Further, the folium artemisiae argyi extract is prepared by cleaning folium artemisiae argyi, adding water, performing ultrasonic extraction, filtering, and concentrating the filtrate; wherein the ultrasonic power is 350-380W, and the extraction time is 40-45 min.
Further, the preparation method of the motherwort extract comprises the steps of grinding motherwort into powder, adding ethanol water solution, carrying out ultrasonic extraction with the ultrasonic power of 350-400W and the extraction time of 25-30min, filtering, extracting filtrate with diethyl ether, removing an organic solvent layer, heating at 50-55 ℃ for 10-15min, centrifuging to obtain supernatant, and concentrating the supernatant.
Further, lavender essential oil and astaxanthin are also included; the contents of lavender essential oil and astaxanthin are 1.5-3.0% and 2.0-3.0%, respectively.
Further, the emulsifier is PEG-6.
In conclusion, the invention has the following beneficial effects:
1. the repairing medical cold compress dressing has the functions of balancing internal secretion and improving immunity, is rich in extracts of effective components such as resveratrol, folium artemisiae argyi, sodium hyaluronate, serine, motherwort herb, pepper seed, purple perilla, hesperidin and the like, can effectively promote the lipolysis process and metabolism, further eliminates orange peel tissues, is matched with effective plant extracts, activates a blood circulation system in a body and has the effects of diminishing inflammation and relieving pain, does not bring pain to skin when in use, and is high in mildness.
2. The motherwort extract is added, so that the Chinese medicinal preparation has the special effects of promoting blood circulation to restore menstrual flow, removing blood stasis and promoting tissue regeneration.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, and the terms used herein in the specification of the present invention are for the purpose of describing particular embodiments only and are not intended to limit the present invention.
Example 1:
the repair type medical cold compress dressing comprises the following substances in percentage by mass:
milk protein: 10.0 percent; serine: 2.5 percent; the folium artemisiae argyi extract: 2.5 percent; apple fruit extract: 3.0 percent; and (3) perilla extract: 3.0 percent; resveratrol: 3.0 percent; sodium hyaluronate: 4.0 percent; motherwort extract: 2.0 percent; pepper seed extract: 2.0 percent; hesperidin: 2.5 percent; purple perilla seed oil: 2.5 percent; walnut oil: 2.0 percent; olive oil: 3.0 percent; borneol: 0.2 percent; PEG-6: 1.0 percent; polyglycerol-6 esters: 1.0 percent; ginger root oil: 2.0 percent; glutathione: 2.0 percent; and (3) extracting the lithospermum: 2.0 percent; the ginseng extract: 2.0 percent; peony root bark extract: 2.0 percent; notopterygium root extract: 4.0 percent; ginger root extract: 3.0 percent; and (3) oat extract: 2.0 percent; lavender essential oil: 2.0 percent; astaxanthin: 3.0 percent; water: and (4) the balance.
Wherein the folium Artemisiae Argyi extract is prepared by cleaning folium Artemisiae Argyi, adding water, performing ultrasonic extraction, filtering, and concentrating the filtrate; wherein the ultrasonic power is 350W, and the extraction time is 30 min.
The preparation method of herba Leonuri extract comprises grinding herba Leonuri into powder, adding ethanol water solution, performing ultrasonic extraction with ultrasonic power of 380W for 30min, filtering, extracting the filtrate with diethyl ether, removing organic solvent layer, heating at 55 deg.C for 10min, centrifuging to obtain supernatant, and concentrating the supernatant.
The preparation method of the repair type medical cold compress dressing comprises the following steps: weighing the components in the formula according to a proportion, firstly adding PEG-6 and astaxanthin into water, stirring uniformly, then adding the rest components in sequence, and after adding one component every time, adding the next component after stirring uniformly to obtain the repair type medical cold compress dressing which is uniformly mixed.
Example 2:
the repair type medical cold compress dressing comprises the following substances in percentage by mass:
milk protein: 8.0 percent; serine: 2.0 percent; the folium artemisiae argyi extract: 1.5 percent; apple fruit extract: 3.5 percent; and (3) perilla extract: 2.0 percent; resveratrol: 4.0 percent; sodium hyaluronate: 4.0 percent; motherwort extract: 2.5 percent; pepper seed extract: 2.0 percent; hesperidin: 2.0 percent; purple perilla seed oil: 3.5 percent; walnut oil: 2.5 percent; olive oil: 2.5 percent; borneol: 0.2 percent; PEG-6: 1.0 percent; polyglycerol-6 esters: 1.0 percent; ginger root oil: 2.5 percent; glutathione: 2.0 percent; and (3) extracting the lithospermum: 1.0 percent; the ginseng extract: 3.0 percent; peony root bark extract: 1.0 percent; notopterygium root extract: 4.0 percent; ginger root extract: 2.0 percent; and (3) oat extract: 2.0 percent; lavender essential oil: 1.5 percent; astaxanthin: 2.5 percent; water: and (4) the balance.
Wherein the folium Artemisiae Argyi extract is prepared by cleaning folium Artemisiae Argyi, adding water, performing ultrasonic extraction, filtering, and concentrating the filtrate; wherein the ultrasonic power is 350W, and the extraction time is 30 min.
The preparation method of herba Leonuri extract comprises grinding herba Leonuri into powder, adding ethanol water solution, performing ultrasonic extraction with ultrasonic power of 380W for 30min, filtering, extracting the filtrate with diethyl ether, removing organic solvent layer, heating at 55 deg.C for 10min, centrifuging to obtain supernatant, and concentrating the supernatant.
The preparation method of the repair type medical cold compress dressing comprises the following steps: weighing the components in the formula according to a proportion, firstly adding PEG-6 and astaxanthin into water, stirring uniformly, then adding the rest components in sequence, and after adding one component every time, adding the next component after stirring uniformly to obtain the repair type medical cold compress dressing which is uniformly mixed.
Example 3:
the repair type medical cold compress dressing comprises the following substances in percentage by mass:
milk protein: 9.0 percent; serine: 1.0 percent; the folium artemisiae argyi extract: 1.5 percent; apple fruit extract: 2.5 percent; and (3) perilla extract: 1.0 percent; resveratrol: 3.0 percent; sodium hyaluronate: 4.5 percent; motherwort extract: 1.5 percent; pepper seed extract: 2.0 percent; hesperidin: 3.0 percent; purple perilla seed oil: 2.5 percent; walnut oil: 3.0 percent; olive oil: 2.0 percent; borneol: 0.2 percent; PEG-6: 1.0 percent; polyglycerol-6 esters: 1.0 percent; ginger root oil: 1.0 percent; glutathione: 2.0 percent; and (3) extracting the lithospermum: 1.0 percent; the ginseng extract: 2.0 percent; peony root bark extract: 2.0 percent; notopterygium root extract: 4.0 percent; ginger root extract: 3.0 percent; and (3) oat extract: 1.0 percent; lavender essential oil: 1.5 percent; astaxanthin: 2.0 percent; water: and (4) the balance.
Wherein the folium Artemisiae Argyi extract is prepared by cleaning folium Artemisiae Argyi, adding water, performing ultrasonic extraction, filtering, and concentrating the filtrate; wherein the ultrasonic power is 350W, and the extraction time is 30 min.
The preparation method of herba Leonuri extract comprises grinding herba Leonuri into powder, adding ethanol water solution, performing ultrasonic extraction with ultrasonic power of 380W for 30min, filtering, extracting the filtrate with diethyl ether, removing organic solvent layer, heating at 55 deg.C for 10min, centrifuging to obtain supernatant, and concentrating the supernatant.
The preparation method of the repair type medical cold compress dressing comprises the following steps: weighing the components in the formula according to a proportion, firstly adding PEG-6 and astaxanthin into water, stirring uniformly, then adding the rest components in sequence, and after adding one component every time, adding the next component after stirring uniformly to obtain the repair type medical cold compress dressing which is uniformly mixed.
Comparative example 1:
comparative example 1 no serine was added, and other ingredients and preparation method were the same as example 1.
Comparative example 2:
comparative example 2 the leonurus extract was not added, and other ingredients and preparation methods were the same as example 1.
And (3) effect testing:
the products obtained in examples 1 to 3 were tested for their effects with the products of comparative examples 1 to 2:
150 patients with rheumatism were selected and randomly divided into 5 groups, and the products of examples 1-3 and comparative examples 1-2 were used, respectively, all patients could use the products as required for 15 days continuously, and the curative effect statistics are as follows.
Wherein, the evaluation standard of the curative effect is as follows:
the effect is shown: the symptoms of rheumatism and pain are obviously improved;
the method has the following advantages: the symptoms are improved and improved, and the pain symptoms are relieved;
and (4) invalidation: the symptoms did not improve or improve, or even tended to be more severe.
Test items | Show effect | Is effective | Invalidation | Significant efficiency (%) |
Example 1 | 49 | 1 | 0 | 98% |
Example 2 | 48 | 2 | 0 | 96% |
Example 3 | 48 | 2 | 0 | 96% |
Comparative example 1 | 34 | 16 | 0 | 68% |
Comparative example 2 | 30 | 15 | 5 | 60% |
The data in the table show that the medical cold compress dressing has obvious curative effect on treating rheumatism and eliminating pain. The repairing medical cold compress dressing has the functions of balancing internal secretion and improving immunity, is rich in extracts of effective components such as resveratrol, folium artemisiae argyi, sodium hyaluronate, serine, motherwort herb, pepper seed, purple perilla, hesperidin and the like, can effectively promote the lipolysis process and metabolism, further eliminates orange peel tissues, is matched with effective plant extracts, activates a blood circulation system in a body and has the effects of diminishing inflammation and relieving pain, does not bring pain to skin when in use, and is high in mildness.
Among them, comparative example 1 showed a decrease in the significant efficiency to 68% without adding serine, and thus it was found that serine plays an important role in the metabolism of fats and fatty acids and the growth of muscles, and contributes to the production of immunocytokines and antibodies, thereby maintaining a healthy immune system.
In the case that the leonurus extract is not added, the significant efficiency is reduced to 60%, and the condition that the use is invalid occurs at the same time, so that the leonurus extract plays an important role in the medical cold compress dressing, and the effects of promoting blood circulation to regulate menstruation, removing blood stasis and promoting tissue regeneration of the medical cold compress dressing can be obviously improved by adding the leonurus extract.
The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may occur to those skilled in the art without departing from the principle of the invention, and are considered to be within the scope of the invention.
Claims (7)
1. The repairing medical cold compress dressing is characterized by comprising the following substances in percentage by mass:
milk protein: 5.0 to 10.0 percent;
serine: 1.0-2.5%;
the folium artemisiae argyi extract: 1.0 to 3.5 percent;
apple fruit extract: 2.0-4.0%;
and (3) perilla extract: 1.0-3.0%;
resveratrol: 3.0 to 5.0 percent;
sodium hyaluronate: 4.0 to 6.0 percent;
motherwort extract: 1.0-3.0%;
pepper seed extract: 1.0-3.0%;
hesperidin: 2.0 to 3.0 percent;
purple perilla seed oil: 1.0 to 3.5 percent;
walnut oil: 2.0 to 3.0 percent;
olive oil: 1.0-3.0%;
borneol: 0.2 to 0.5 percent;
emulsifier: 0.05 to 1.5 percent;
polyglycerol-6 esters: 0.05 to 1.0 percent
Ginger root oil: 1.0-3.0%;
glutathione: 1.0-3.0%;
plant extracts: 10.5 to 28.0 percent;
water: and (4) the balance.
2. The restorative-type medical cold compress dressing of claim 1, wherein the plant extract comprises a lithospermum erythrorhizon extract, a ginseng extract, a peony root bark extract, a notopterygium root extract, and a ginger root extract; the contents of the lithospermum extract, the ginseng extract, the peony root bark extract, the notopterygium root extract and the ginger root extract are respectively 2.0-4.0%, 2.0-5.0%, 1.0-3.0%, 4.0-6.0% and 2.0-4.0%.
3. The prosthetic medical cold compress dressing of claim 2, wherein the plant extract further comprises oat extract; the content of the oat extract is 1.0-3.0%.
4. The repair type medical cold compress dressing according to claim 2, wherein the folium artemisiae argyi extract is prepared by cleaning folium artemisiae argyi, adding water, performing ultrasonic extraction, filtering, and concentrating the filtrate; wherein the ultrasonic power is 350-380W, and the extraction time is 40-45 min.
5. The repair type medical cold compress dressing as claimed in claim 2, wherein the herba Leonuri extract is prepared by grinding herba Leonuri into powder, adding ethanol water solution, performing ultrasonic extraction with ultrasonic power of 350-400W for 25-30min, filtering, extracting the filtrate with diethyl ether, removing organic solvent layer, heating at 50-55 deg.C for 10-15min, centrifuging to obtain supernatant, and concentrating the supernatant.
6. The repair medical cold compress dressing of claim 1, further comprising lavender essential oil and astaxanthin; the contents of lavender essential oil and astaxanthin are 1.5-3.0% and 2.0-3.0%, respectively.
7. The repair medical cold compress dressing according to claim 1, wherein the emulsifier is PEG-6.
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CN111568780A (en) * | 2020-05-09 | 2020-08-25 | 广东华辰凯太健康管理有限公司 | Herbal gel with myotonin and preparation method thereof |
CN112089883A (en) * | 2020-09-14 | 2020-12-18 | 海南希睿达生物技术有限公司 | Medical cold compress dressing and preparation method thereof |
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Patent Citations (3)
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CN110101639A (en) * | 2019-06-17 | 2019-08-09 | 广州南雪药业有限公司 | Vigor frost and preparation method thereof |
CN111568780A (en) * | 2020-05-09 | 2020-08-25 | 广东华辰凯太健康管理有限公司 | Herbal gel with myotonin and preparation method thereof |
CN112089883A (en) * | 2020-09-14 | 2020-12-18 | 海南希睿达生物技术有限公司 | Medical cold compress dressing and preparation method thereof |
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