CN104644501A - Composition with acne removal and restoration effects and preparation method thereof - Google Patents
Composition with acne removal and restoration effects and preparation method thereof Download PDFInfo
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- CN104644501A CN104644501A CN201510059176.9A CN201510059176A CN104644501A CN 104644501 A CN104644501 A CN 104644501A CN 201510059176 A CN201510059176 A CN 201510059176A CN 104644501 A CN104644501 A CN 104644501A
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Abstract
The embodiment of the invention discloses a composition with acne removal and restoration effects. The composition comprises the following components in percentage by mass: 50-80% of alcohol, 15-40% of chloramphenicol, 0.1-5% of glycerol, and 0.1-5% of a cactus extract. The embodiment of the invention also discloses a preparation method of the composition with acne removal and restoration effects, and the preparation method comprises the following steps: at a temperature of 30-40 DEG C, putting the components of the composition into a stirring container and uniformly stirring, so that a mixture is obtained; and at a temperature of 10-15 DEG C, and in a vacuum and sterile environment, filling the mixture, so that a finished product is obtained. According to the composition, by optimizing a formula of acne removing products, acnes on the skin can be nourished well, so that the composition has relatively ideal acne removal and restoration effects.
Description
Technical field
The present invention relates to skin-protection product technical field, specifically a kind of composition and method of making the same that there is anti-acne and repair effect.
Background technology
Comedo claims " acne " in the traditional Chinese medical science, " acne " is claimed in doctor trained in Western medicine, a kind of chronic inflammatory skin being pilosebaceous unit is sick, its clinical manifestation be apt to occur in face, cervical region, chest and back, shoulder the pleomorphism skin lesion such as acne, pimple, pustule, tuberosity for feature.The pathogeny of comedo is, hormone meeting stimulating hair growth higher in human body, promotes smegma more heavy wool fat; Therefore hair and sebaceous gland pile up many materials, cause oils and fats and bacterial adhesion to there is discharge obstacle in sebum; Multiple-microorganism especially propionibacterium acnes amount reproduction in sebum hair follicle, the lipase of generation decomposes sebum and generates free fatty, simultaneously chemotactic inflammatory cell and medium, final induction also exacerbate inflammation reaction; When the damage of skin is dark and corium or large-area skin blemish time, the epidermis at this position can not regenerate, and occurs pockmark thus.
Comedo is mainly apt to occur in teenager, makes a big impact to teen-age psychology and social activity.For this reason, there is various product for resolving poxes on the market.The following problem of these product for resolving poxes ubiquities: (1) is large to skin irritation, easily causes skin allergy; (2) too large to the side effect of skin, damage healthy; (3) recurrent is strong, can not thoroughly effect a radical cure; (4) easily leave cicatrix after anti-acne, affect user appearance.In view of existing product for resolving poxes effect is single, comprehensively can not nurse the acne of skin, be necessary that researching and developing the better anti-acne of a kind of performance repairs product.
Summary of the invention
For the defect that prior art exists, the object of the embodiment of the present invention is to provide a kind of composition and method of making the same having anti-acne and repair effect, can acne that is safer, skin effectively nurse.
For solving above technical problem, the embodiment of the present invention provides a kind of compositions having anti-acne and repair effect, and described compositions by percentage to the quality, comprising: ethanol, and 50% ~ 80%; Chloromycetin, 15% ~ 40%; Glycerol, 0.1% ~ 5%; Radix et Caulis Opuntiae Dillenii extract, 0.1% ~ 5%.
More preferably, described compositions by percentage to the quality, comprising: ethanol, and 60% ~ 75%; Chloromycetin, 20% ~ 35%; Glycerol, 0.5% ~ 4%; Radix et Caulis Opuntiae Dillenii extract, 0.5% ~ 4%.
More preferably, described compositions by percentage to the quality, comprising: ethanol, and 65% ~ 70%; Chloromycetin, 25% ~ 30%; Glycerol, 1% ~ 3%; Radix et Caulis Opuntiae Dillenii extract, 1% ~ 3%.
More preferably, described compositions by percentage to the quality, comprising: the Chinese traditional medicine's extractant having heat-clearing toxin-expelling functions, 2% ~ 10%.
More preferably, described compositions by percentage to the quality, comprising: the Chinese traditional medicine's extractant having heat-clearing toxin-expelling functions, 4% ~ 8%.
More preferably, described in have the crude drug of the Chinese traditional medicine's extractant of heat-clearing toxin-expelling functions in mass parts, comprising: Folium Eriobotryae 5 ~ 10 parts; Flos Chrysanthemi 5 ~ 10 parts; Cortex Mori 5 ~ 10 parts; Radix Sophorae Flavescentis 5 ~ 10 parts; Radix Paeoniae Rubra 10 ~ 15 parts; Cortex Moutan 5 ~ 10 parts; Radix Glycyrrhizae 5 ~ 10 parts.
More preferably, described in have the crude drug of the Chinese traditional medicine's extractant of heat-clearing toxin-expelling functions in mass parts, comprising: Folium Eriobotryae 6 ~ 8 parts; Flos Chrysanthemi 6 ~ 8 parts; Cortex Mori 6 ~ 8 parts; Radix Sophorae Flavescentis 6 ~ 8 parts; Radix Paeoniae Rubra 8 ~ 12 parts; Cortex Moutan 8 ~ 12 parts; Radix Glycyrrhizae 6 ~ 8 parts.
More preferably, described Radix et Caulis Opuntiae Dillenii extract is Opuntia Streptacantha stem extract.
On this basis, the embodiment of the present invention also provides a kind of preparation method with the compositions of anti-acne and reparation effect, comprise the following steps: under 30 DEG C ~ 40 DEG C environment, each component in the above compositions is put into stirred vessel and stirs evenly, obtain mixture; 10 DEG C ~ 15 DEG C, vacuum, under gnotobasis, be finished product by mixture fill.
More preferably, adopt Medical constant-temperature magnetic stirring apparatus, mixing speed is 100 ~ 150 revs/min, and mixing time is 5 ~ 10 minutes.
The embodiment of the present invention can be different dosage form as carrier, ethanol wherein can be sterilized, and chloromycetin can antimicrobial therapy, and glycerol can skin care, scar, reparation and the hydroxymalonic acid contained in Radix et Caulis Opuntiae Dillenii extract and triterpenoid saponin can be dispelled.By the rational proportion of these components, product for resolving poxes of the present invention can be nursed the acne of skin well, there is good anti-acne and repairing effect.Compared with prior art, products obtained therefrom of the present invention is safer, effective, and its raw material obtains simple, and preparation method is convenient, is easy to be accepted by consumers in general, has good application prospect and market prospect.
Accompanying drawing explanation
Fig. 1 is the flow chart that the embodiment of the present invention has the preparation method of the compositions of anti-acne and reparation effect.
Detailed description of the invention
In order to understand know-why and the work process of the embodiment of the present invention better, describe the present invention further below in conjunction with drawings and the specific embodiments.
In the embodiment of the present invention, there is anti-acne and repair efficacy (hereinafter referred to as product of the present invention) and mainly comprise the components such as ethanol, chloromycetin, glycerol, Radix et Caulis Opuntiae Dillenii extract, wherein the proportioning of each component is: ethanol accounts for 50% ~ 80% of gross mass, and its Main Function is sterilization; Chloromycetin accounts for 15% ~ 40% of gross mass, and its Main Function is antimicrobial therapy; Glycerol accounts for 0.1% ~ 5% of gross mass, and its Main Function is skin care; Radix et Caulis Opuntiae Dillenii extract accounts for 0.1% ~ 5% of gross mass, is preferably Opuntia Streptacantha stem extract, and it has hydroxymalonic acid compared with horn of plenty and triterpenoid saponin, can dispel well scar, reparation.
The more excellent embodiment of one of product of the present invention is: by percentage to the quality, and ethanol is 60% ~ 75%, and chloromycetin is 20% ~ 35%, and glycerol is 0.5% ~ 4%, and Radix et Caulis Opuntiae Dillenii extract is 0.5% ~ 4%.More excellent embodiment is: by percentage to the quality, and ethanol is 65% ~ 70%, and chloromycetin is 25% ~ 30%, and glycerol is 1% ~ 3%, and Radix et Caulis Opuntiae Dillenii extract is 1% ~ 3%.
In product of the present invention, the antibacterial of skin surface can kill by ethanol, plays the sterilization to skins such as faces; Chloromycetin has antibacterial effect, suppresses rapidly and kills the Growth and Reproduction of antibacterial in acne, acne; Glycerol has the effect of skin protection moisturizing, moisturizing speckle dispelling; Radix et Caulis Opuntiae Dillenii extract has the effect of promoting flow of QI and blood, heat-clearing and toxic substances removing, has eliminating toxin and beautifying the skin special effect to the acne of face, acne.By the rational proportion to above-mentioned component, product of the present invention is made to have good speckle dispelling and repairing effect.
In the embodiment of the present invention, can add the Chinese traditional medicine's extractant of heat-clearing toxin-expelling functions further, it, by clearing away heat and expelling wind, pathogenic fire reducing toxin expelling, removing heat from blood dampness removing, is conducive to anti-acne better.By percentage to the quality, accounting is 2% ~ 10% to the Chinese traditional medicine's extractant of these heat-clearing toxin-expelling functions, is preferably 4% ~ 8%.After adding these Chinese traditional medicine's extractants, correspondingly can reduce the content of ethanol and chloromycetin, repeat no more.
Above-mentioned Chinese traditional medicine's extractant specifically can adopt following formula, and its crude drug is in mass parts: comprise Folium Eriobotryae 5 ~ 10 parts; Flos Chrysanthemi 5 ~ 10 parts; Cortex Mori 5 ~ 10 parts; Radix Sophorae Flavescentis 5 ~ 10 parts; Radix Paeoniae Rubra 10 ~ 15 parts; Cortex Moutan 5 ~ 10 parts; Radix Glycyrrhizae 5 ~ 10 parts.Preferably, following formula can be adopted: Folium Eriobotryae 6 ~ 8 parts; Flos Chrysanthemi 6 ~ 8 parts; Cortex Mori 6 ~ 8 parts; Radix Sophorae Flavescentis 6 ~ 8 parts; Radix Paeoniae Rubra 8 ~ 12 parts; Cortex Moutan 8 ~ 12 parts; Radix Glycyrrhizae 6 ~ 8 parts.
The better example of one of above-mentioned Chinese traditional medicine's extractant gets Folium Eriobotryae 7 parts; Flos Chrysanthemi 7 parts; Cortex Mori 7 parts; Radix Sophorae Flavescentis 7 parts; Radix Paeoniae Rubra 10 parts; Cortex Moutan 10 parts; Radix Glycyrrhizae 7 parts is crude drug; By these crude drug first by cold water soak to deliquescing, cell wall expansion; Add the water of roughly equivalent, within 10 ~ 15 minutes with high heat, be fried boiling; Afterwards, 45 ~ 60 minutes are decocted again with slow fire; Cool rear taking-up is for subsequent use, joins product of the present invention with other component systems of coming together.
Below illustrate and product of the present invention and preparation method be described in detail:
Embodiment 1
The present embodiment component and formula are: ethanol, 70%; Chloromycetin, 28%; Glycerol, 1%; Radix et Caulis Opuntiae Dillenii extract, 1%.
The compounding method of the present embodiment is as shown in Figure 1:
Step S101, prepare above-mentioned component;
Step S102, with electric furnace or other firing equipment, stirred vessel is warming up to 30 DEG C ~ 40 DEG C;
Step S103, add above-mentioned component successively;
Step S104, stir evenly in stirred vessel above-mentioned component is stirred evenly, obtain mixture.The performance indications of the visual agitator product of technological parameter are herein selected, and such as: for Medical constant-temperature magnetic stirring apparatus, mixing speed gets 120 revs/min, mixing time gets 8 minutes, can reach ideal mixing effect.
Step S105, cool to 10 DEG C ~ 15 DEG C;
Step S106, under vacuum, gnotobasis, be finished product by mixture fill.
The feature of the present embodiment product is: scar of dispelling Be very effective, anti-inflammatory effects is relatively good.
Embodiment 2
The present embodiment component and formula are: ethanol, 69%; Chloromycetin, 30%; Glycerol, 0.5%; Radix et Caulis Opuntiae Dillenii extract, 0.5%.
Preparation method is with embodiment 1.
Products characteristics is: show as anti-inflammatory effects remarkable.
Embodiment 3
The present embodiment component and formula are: ethanol, 72.5%; Chloromycetin, 25%; Glycerol, 1%; Radix et Caulis Opuntiae Dillenii extract, 1.5%.
Preparation method is with embodiment 1.
Products characteristics is: show as anti-inflammatory effects relatively good, and oil-control is good.
Embodiment 4
The present embodiment component and formula are: ethanol, 65%; Chloromycetin, 32%; Glycerol, 1.5%; Radix et Caulis Opuntiae Dillenii extract, 1.5%.
Preparation method is with embodiment 1.
Products characteristics is: show as therapeutic effect obvious.
Embodiment 5
The present embodiment adds Chinese traditional medicine's extractant, and concrete component and formula are: ethanol, 60%; Chloromycetin, 30%; Glycerol, 1.5%; Radix et Caulis Opuntiae Dillenii extract, 1.5%; Chinese traditional medicine's extractant, 7%.
In the preparation method of the present embodiment: need get out Chinese traditional medicine's extractant in advance, crude drug and preparation method please see above; Other step is with embodiment 1.
Products characteristics is: heat-clearing and toxic substances removing, regulating body function, and therapeutic effect is more obvious.
Using method and points for attention
The using method of product of the present invention is: product is applied to affected part, about 2 hours onsets.As met allergic phenomena, allergy sufferers shows as affected part decortication, and processing method is drug withdrawal immediately, and within three days, (72 hours) disappear certainly.
Product of the present invention answers points for attention in use: (1) keeping life is 1 year, expiredly must not use; (2) anemia of pregnant woman's forbidding; (3) forbid that large area is smeared; (4) away from naked light; (5) this product of use must not more than 2 months continuously; (6) alcohol intolerance person is forbidden; (7) be cautious use of menstrual period; Child below (8) 16 one full year of life is forbidden; (9) avoid during using this product: pungent, greasy, fry, tobacco and wine.
Clinical test results
Product of the present invention can kill the corynebacterium, Staphylococcus albus, the circular sugared rash sporeformer of print etc. that exist in hair follicle, is conducive to anti-acne reparation.Concrete anti-acne repairing effect evaluation criterion is: (1) is obvious: clinical symptom disappearance, erythra acne disappear; (2) general: clinical symptom relief, erythra acne partial remission or disappearance, reduce or reduce; (3) poor: clinical symptoms, erythra acne have no improvement.
Table 1, by teenager use (wherein men and women half and half) giving 100 comedo symptoms similar respectively, checks anti-acne effect.Shown within 15 days, test result is specific as follows:
Table 1 clinical test results summary sheet
| Effect | Number |
| Anti-acne effect obviously (man) | 40 |
| Anti-acne effect general (man) | 8 |
| Anti-acne effect poor (man) | 2 |
| Anti-acne effect obviously (female) | 38 |
| Anti-acne effect general (female) | 9 |
| Anti-acne effect poor (female) | 3 |
Above-mentioned clinical test results shows: product safety of the present invention, effectively, its effective percentage reaches 100%, and cure rate is up to more than 90%.
Embodiment of the present invention medical material used all can be bought from China Medicament Group Corp. and obtain, and its raw material obtains simple, and preparation method is convenient, is easy to be accepted by consumers in general, has good application prospect and market prospect.
Although the present invention with preferred embodiment openly as above; but it is not for limiting the present invention; any those skilled in the art without departing from the spirit and scope of the present invention; can make possible variation and amendment, the scope that therefore protection scope of the present invention should define with the claims in the present invention is as the criterion.
Claims (10)
1. have the compositions of anti-acne and reparation effect, it is characterized in that, described compositions by percentage to the quality, comprising: ethanol, and 50% ~ 80%; Chloromycetin, 15% ~ 40%; Glycerol, 0.1% ~ 5%; Radix et Caulis Opuntiae Dillenii extract, 0.1% ~ 5%.
2. compositions as claimed in claim 1, it is characterized in that, described compositions by percentage to the quality, comprising: ethanol, and 60% ~ 75%; Chloromycetin, 20% ~ 35%; Glycerol, 0.5% ~ 4%; Radix et Caulis Opuntiae Dillenii extract, 0.5% ~ 4%.
3. compositions as claimed in claim 2, it is characterized in that, described compositions by percentage to the quality, comprising: ethanol, and 65% ~ 70%; Chloromycetin, 25% ~ 30%; Glycerol, 1% ~ 3%; Radix et Caulis Opuntiae Dillenii extract, 1% ~ 3%.
4. compositions as claimed in claim 1, it is characterized in that, described compositions by percentage to the quality, comprising: the Chinese traditional medicine's extractant having heat-clearing toxin-expelling functions, 2% ~ 10%.
5. compositions as claimed in claim 4, it is characterized in that, described compositions by percentage to the quality, comprising: the Chinese traditional medicine's extractant having heat-clearing toxin-expelling functions, 4% ~ 8%.
6. compositions as claimed in claim 4, is characterized in that, described in have the crude drug of the Chinese traditional medicine's extractant of heat-clearing toxin-expelling functions in mass parts, comprising: Folium Eriobotryae 5 ~ 10 parts; Flos Chrysanthemi 5 ~ 10 parts; Cortex Mori 5 ~ 10 parts; Radix Sophorae Flavescentis 5 ~ 10 parts; Radix Paeoniae Rubra 10 ~ 15 parts; Cortex Moutan 5 ~ 10 parts; Radix Glycyrrhizae 5 ~ 10 parts.
7. compositions as claimed in claim 6, is characterized in that, described in have the crude drug of the Chinese traditional medicine's extractant of heat-clearing toxin-expelling functions in mass parts, comprising: Folium Eriobotryae 6 ~ 8 parts; Flos Chrysanthemi 6 ~ 8 parts; Cortex Mori 6 ~ 8 parts; Radix Sophorae Flavescentis 6 ~ 8 parts; Radix Paeoniae Rubra 8 ~ 12 parts; Cortex Moutan 8 ~ 12 parts; Radix Glycyrrhizae 6 ~ 8 parts.
8. the compositions as described in any one of claim 1 ~ 7, is characterized in that, described Radix et Caulis Opuntiae Dillenii extract is Opuntia Streptacantha stem extract.
9. one kind has the preparation method of the compositions of anti-acne and reparation effect, it is characterized in that, comprise the following steps: under 30 DEG C ~ 40 DEG C environment, each component in compositions as described in any one of claim 1 ~ 8 is put into stirred vessel and stirs evenly, obtain mixture; 10 DEG C ~ 15 DEG C, vacuum, under gnotobasis, be finished product by mixture fill.
10. preparation method as claimed in claim 9, is characterized in that, adopt Medical constant-temperature magnetic stirring apparatus, mixing speed is 100 ~ 150 revs/min, and mixing time is 5 ~ 10 minutes.
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| CN201510059176.9A CN104644501A (en) | 2015-02-05 | 2015-02-05 | Composition with acne removal and restoration effects and preparation method thereof |
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| CN201510059176.9A CN104644501A (en) | 2015-02-05 | 2015-02-05 | Composition with acne removal and restoration effects and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109806219A (en) * | 2019-04-03 | 2019-05-28 | 朱方芳 | A kind of daubing-type facial mask for repairing cuticula |
| CN110522782A (en) * | 2019-10-17 | 2019-12-03 | 王济兴 | With bactericidal antiphlogistic, the traditional Chinese medicinal ointment of antipruritic analgesic effect and preparation method thereof |
| CN110721250A (en) * | 2019-09-12 | 2020-01-24 | 武汉润欣科技股份有限公司 | Traditional Chinese medicine extract and acne removing liquid containing same |
-
2015
- 2015-02-05 CN CN201510059176.9A patent/CN104644501A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109806219A (en) * | 2019-04-03 | 2019-05-28 | 朱方芳 | A kind of daubing-type facial mask for repairing cuticula |
| CN110721250A (en) * | 2019-09-12 | 2020-01-24 | 武汉润欣科技股份有限公司 | Traditional Chinese medicine extract and acne removing liquid containing same |
| CN110522782A (en) * | 2019-10-17 | 2019-12-03 | 王济兴 | With bactericidal antiphlogistic, the traditional Chinese medicinal ointment of antipruritic analgesic effect and preparation method thereof |
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Address after: Huang Shan Zhen 311809 Zhejiang city of Shaoxing province Zhuji City, the East Road No. 66 Zhuji Gengxing environmental protection equipment Co. Ltd. Applicant after: Jin Yuliang Address before: Old Zhou Zhen Zhuang Cun, Tongxin County, Wuzhong City, the Ningxia Hui Autonomous Region Wei 257 751303 Applicant before: Jin Yuliang |
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Address after: Old Zhou Zhen Zhuang Cun, Tongxin County, Wuzhong City, the Ningxia Hui Autonomous Region Wei 257 751303 Applicant after: Jin Yuliang Address before: Huang Shan Zhen 311809 Zhejiang city of Shaoxing province Zhuji City, the East Road No. 66 Zhuji Gengxing environmental protection equipment Co. Ltd. Applicant before: Jin Yuliang |
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Application publication date: 20150527 |