CN105477081A - Preparation method of acne removal medicine liquid - Google Patents
Preparation method of acne removal medicine liquid Download PDFInfo
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- CN105477081A CN105477081A CN201510953223.4A CN201510953223A CN105477081A CN 105477081 A CN105477081 A CN 105477081A CN 201510953223 A CN201510953223 A CN 201510953223A CN 105477081 A CN105477081 A CN 105477081A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a preparation method of acne removal medicine liquid, and relates to a preparation method of a medicine for removing acnes. The acne removal medicine liquid is invented mainly to solve the problem of an existing acne removal product which, when used for a long time, can cause skin dependent dermatitis and like side effects, and to solve the problems that a heat and toxic material clearing traditional Chinese medicine is high in treatment expense, long in treatment course and poor in effect. The preparation method comprises the following steps: firstly, preparing a traditional Chinese medicine stock solution: soaking 1kg of radix et rhizoma rhei, 1.5kg of radix sophorae flavescentis and 1.5kg of cortex pseudolaricis in 10kg of 40-degree edible Baijiu for 30 days at normal temperature; grinding five chlortrimeton tablets into powder; grinding five dexamethasone tablets into powder; and adding the chlortrimeton powder and the dexamethasone tablet powder which are ground according to the weight as well as 0.1g of borneol powder and 5ml of medical glycerol to 30ml of the traditional Chinese medicine stock solution, and uniformly mixing, so that the acne removal medicine liquid is obtained. The acne removal medicine liquid disclosed by the invention has the advantages of being short in treatment course, good in treatment effect, free from toxic and side effects and low in expense.
Description
Technical field:
The present invention relates to a kind of preparation method of medicine of anti-acne.
Background technology:
The factors such as the generation of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.Patient mostly is adolescence men and women, and skin lesion is apt to occur in facial area, especially forehead, cheeks and chin portion, also goes up the position that the sebaceous gland such as breast, omoplate back is abundant as seen.Product for resolving poxes commercially available at present, in order to pursue significant effect, often adds hormone skin being had to larger stimulation in product, and life-time service can form the side effect such as skin dependence facial dermatitis.Also have the injection injected to beauty parlor and improve immunologic function, these injections often costly, substantially without any curative effect.In the treatment of medical heat and toxic materials clearing away medicine thing, costly, the course for the treatment of is long, weak effect.
Summary of the invention:
Technical problem to be solved by this invention is to provide a kind of preparation method of anti-acne medicine, and the short treating period of the anti-acne Drug therapy anti-acne obtained by this preparation method, therapeutic effect is good, has no side effect, and expense is few.
Above-mentioned purpose is achieved in that and first makes Chinese medicine stock solution, method be get Radix Et Rhizoma Rhei 1 kilogram, Radix Sophorae Flavescentis 1.5 kilograms, Cortex Pseudolaricis 1.5 kilograms put in 40 ° of edible distillate spirits 10 kilograms, soak at room temperature 30 days;
By 5 chlorpheniramine maleate tabletses (4 milli gram/piece) pulverize;
By 5 dexamethasone tablets (0.75 milli gram/piece) pulverize;
Join in the Chinese medicine stock solution of 30 milliliters by the borneol powder of the chlorphenamine powder worn into by above-mentioned weight, dexamethasone tablet powder and 0.1 gram and 5 milliliters of medical glycerol, mix homogeneously can obtain anti-acne medicinal liquid.
If acne infection is serious, desirable anti-acne medicinal liquid 30 milliliters, add injection liquid of gentamicin 2 milliliters, chloramphenicol inj 2 milliliters, cimetidine inj 2 milliliters, mix homogeneously can use.
Using method: smear affected part with cotton swab dip in liquid medicine after washing one's face in morning, evening, can cure for general 5-7 days.
Advantage of the present invention is: short treating period, and therapeutic effect is good, has no side effect, and expense is few.Radix Et Rhizoma Rhei has heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, effect of eliminating blood stasis and inducing menstruation; Radix Sophorae Flavescentis has heat clearing and damp drying, effect of wind dispelling insecticide; Cortex Pseudolaricis has effect of Anti-Puritic and insecticidal.Edible distillate spirit has the effect of sterilization.
Detailed description of the invention:
First make Chinese medicine stock solution, method be get Radix Et Rhizoma Rhei 1 kilogram, Radix Sophorae Flavescentis 1.5 kilograms, Cortex Pseudolaricis 1.5 kilograms put in 40 ° of edible distillate spirits 10 kilograms, soak at room temperature 30 days;
By 5 chlorpheniramine maleate tabletses (4 milli gram/piece) pulverize;
By 5 dexamethasone tablets (0.75 milli gram/piece) pulverize;
Join in the Chinese medicine stock solution of 30 milliliters by the borneol powder of the chlorphenamine powder worn into by above-mentioned weight, dexamethasone tablet powder and 0.1 gram and 5 milliliters of medical glycerol, mix homogeneously can obtain anti-acne medicinal liquid.
If acne infection is serious, desirable anti-acne medicinal liquid 30 milliliters, add injection liquid of gentamicin 2 milliliters, chloramphenicol inj 2 milliliters, cimetidine inj 2 milliliters, mix homogeneously can use.
Using method: smear affected part with cotton swab dip in liquid medicine after washing one's face in morning, evening, can cure for general 5-7 days.
The curative effect table of the anti-acne medicinal liquid obtained by this preparation method: wherein patients with acne medication 5 days, acne infection patient medication 7 days;
| Sex | Age | Case | Symptom | Cure | Take a turn for the better | Invalid | Cure rate | Effective percentage |
| Man | 16-30 | 322 | Acne | 318 | 3 | 1 | 98.7% | 99.6% |
| Female | 16-30 | 455 | Acne | 450 | 5 | 0 | 98.9% | 100% |
| Man | 16-30 | 148 | Acne infection | 145 | 2 | 1 | 97.9% | 99.3% |
| Female | 16-30 | 98 | Acne infection | 95 | 3 | 0 | 96.9% | 100% |
Claims (2)
1. a preparation method for anti-acne medicinal liquid, is characterized in that: first make Chinese medicine stock solution, method be get Radix Et Rhizoma Rhei 1 kilogram, Radix Sophorae Flavescentis 1.5 kilograms, Cortex Pseudolaricis 1.5 kilograms put in 40 ° of edible distillate spirits 10 kilograms, soak at room temperature 30 days;
By 5 chlorpheniramine maleate tablets pulverizes;
By 5 dexamethasone tablet pulverizes;
Join in the Chinese medicine stock solution of 30 milliliters by the borneol powder of the chlorphenamine powder worn into by above-mentioned weight, dexamethasone tablet powder and 0.1 gram and 5 milliliters of medical glycerol, mix homogeneously can obtain anti-acne medicinal liquid.
2. according to the preparation method of anti-acne medicinal liquid according to claim 1, it is characterized in that: get anti-acne medicinal liquid 30 milliliters, add injection liquid of gentamicin 2 milliliters, chloramphenicol inj 2 milliliters, cimetidine inj 2 milliliters, mix homogeneously can use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510953223.4A CN105477081A (en) | 2015-12-20 | 2015-12-20 | Preparation method of acne removal medicine liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510953223.4A CN105477081A (en) | 2015-12-20 | 2015-12-20 | Preparation method of acne removal medicine liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105477081A true CN105477081A (en) | 2016-04-13 |
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ID=55664596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510953223.4A Pending CN105477081A (en) | 2015-12-20 | 2015-12-20 | Preparation method of acne removal medicine liquid |
Country Status (1)
| Country | Link |
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| CN (1) | CN105477081A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267146A (en) * | 2016-09-30 | 2017-01-04 | 郭灵医 | A kind of external preparation for skin medicine for anti-acne and preparation method thereof |
-
2015
- 2015-12-20 CN CN201510953223.4A patent/CN105477081A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 田霞等: "中、西药擦剂治疗痊疮50例", 《第四届东南亚地区医学美容学术大会论文汇编》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267146A (en) * | 2016-09-30 | 2017-01-04 | 郭灵医 | A kind of external preparation for skin medicine for anti-acne and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160413 |