CN103893422B - Repair medicine of skin injury and preparation method thereof - Google Patents
Repair medicine of skin injury and preparation method thereof Download PDFInfo
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- CN103893422B CN103893422B CN201410154749.1A CN201410154749A CN103893422B CN 103893422 B CN103893422 B CN 103893422B CN 201410154749 A CN201410154749 A CN 201410154749A CN 103893422 B CN103893422 B CN 103893422B
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Abstract
The present invention relates to the field of Chinese medicines, more particularly to repairs medicine of skin injury and preparation method thereof.Wherein, the medicine includes the externally dressing consisted of the following composition：By weight, 20 25 parts of egg yolk oil, 15 25 parts of tetratigma hemsleyanum, 15 20 parts of Angelica oil, 10 15 parts of Lavender, 25 40 parts of sesame oil.The medicine of the reparation skin injury has good therapeutic effect to various degrees of skin injury, especially has unique curative effect to deep two degree of skin traumas, is mainly reflected in：Direct external application can treat, without carrying out skin grafting；Treatment cycle is short, clinical tests prove that, during two degree of skin traumas deep with the drug therapy of the reparation skin injury of the present invention, it can fully recover within 23 weeks, at least be shortened 10 30 days relative to traditional skin grafting course for the treatment of；It can relieve pain, anti-inflammation, protect the surface of a wound not infected, wound healing, reproducibility reparation be carried out to skin；Safety has no side effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to medicine for repairing skin injury and preparation method thereof.
Background technology
Skin is one critically important of barrier of human body, can both prevent internal water, electrolyte and other materials nutrients
The loss of matter, the intrusion of extraneous harmful substance can be prevented again.In addition, skin also directly affects the attractive in appearance of people.As can be seen here, skin
The health degree of skin is most important to human body.
In correlation technique, it is varied to repair the medicine of skin injury, including Chinese medicine and Western medicine, but these medicines are general only
Skin minor trauma can be treated, and for deep two degree（That is depthⅡ°）But difficulty is larger for skin trauma.At present, for deep two degree of skins
A kind of conventional treatment method of skin wound is skin grafting, and skin grafting has following technical disadvantages：It is complicated to treat flow, relies on
In surgical surgical technic；Increase patient's physiology and the pain of psychology；Medical expense is expensive.
The content of the invention
It is above-mentioned to solve the problems, such as it is an object of the invention to provide medicine for repairing skin injury and preparation method thereof.
A kind of medicine of reparation skin injury is provided in an embodiment of the present invention, including is consisted of the following composition outer
Application：By weight, egg yolk oil 20-25 parts, tetratigma hemsleyanum 15-25 parts, Angelica oil 15-20 parts, Lavender 10-15
Part, sesame oil 25-40 parts.
Further, by weight, egg yolk oil 23-25 parts, tetratigma hemsleyanum 15-25 parts, Angelica oil 18-20 parts, smoke clothing
Careless essential oil 10-15 parts, sesame oil 25-40 parts.
Further, by weight, egg yolk oil 20-25 parts, tetratigma hemsleyanum 20-25 parts, Angelica oil 15-20 parts, smoke clothing
Careless essential oil 10-15 parts, sesame oil 30-40 parts.
Further, by weight, egg yolk oil 20-25 parts, tetratigma hemsleyanum 15-25 parts, Angelica oil 17-20 parts, smoke clothing
Careless essential oil 13-15 parts, sesame oil 35-40 parts.
The preparation method of the medicine of above-mentioned reparation skin injury, including following step are additionally provided in an embodiment of the present invention
Suddenly：
Step A：Sesame oil is heated to 50-75 DEG C；
Step B：Tetratigma hemsleyanum is added into the sesame oil after heating, then sesame oil is kept 60- at 50-75 DEG C
90min, obtain the first mixture；
Step C：First mixture is filtered, obtains filtrate；
Step D：Angelica oil, Lavender and egg yolk oil are added into filtrate, and is stirred, obtains product.
Further, the method for filtering is：With the membrane filtration of 200 mesh.
Further, in step D, added into filtrate before Angelica oil, Lavender and egg yolk oil, in addition to：First
Filtrate is heated to 50-75 DEG C.
Further, in step D, Angelica oil, Lavender and egg yolk oil are added into filtrate can use following
One mode：
Mode one, while add Angelica oil, Lavender and egg yolk oil；
Mode two, it is separately added into Angelica oil, Lavender and egg yolk oil.
The medicine of the reparation skin injury of the above embodiment of the present invention is by egg yolk oil, tetratigma hemsleyanum, Angelica oil, lavender
The Chinese medicine of five kinds of medicinal material compositions of essential oil and sesame oil, it has good therapeutic effect to various degrees of skin injury, especially
It is to have unique curative effect to deep two degree of skin traumas, unique curative effect is mainly reflected in：One, direct external application can treat, without entering
Row skin grafting, greatly alleviate patient's physiology and psychological pain；Two, treatment cycle is short, clinical tests prove that, with this
During drug therapy two degree of skin traumas deeply of the reparation skin injury of invention, it can fully recover within 2-3 weeks, relative to traditional skin-grafting hand
The art course for the treatment of at least shortens 10-30 days；Three, it can relieve pain, anti-inflammation, protect the surface of a wound not infected, wound healing, from
And formation and the hyperplasia of scar are significantly inhibited, reproducibility reparation is carried out to skin；Four, have no side effect safely, counterpart eye mucosa etc.
Organize non-stimulated.Five, significantly reduce medical expense.
The formulation principle of the medicine of the reparation skin injury of the above embodiment of the present invention is：Egg yolk oil is warm-natured, has detumescence
Removing toxic substances, the effect of expelling pus and promoting granulation, matching with sesame oil can relieve pain, restrain the surface of a wound, reduces body fluid and oozes out, wound healing,
Sesame oil is with egg yolk oil and is the monarch drug in a prescription in side, is mainly used to the hemostasis and pain-relieving of wound, injected organism tissue reparation, suppresses scar hyperplasia；
Tetratigma hemsleyanum, has clearing heat and detoxicating, outer to be used to controlling venomous snake bite, cellulitis, traumatic injury, and tetratigma hemsleyanum coordinates monarch drug in a prescription
Disinfected for anti-inflammatory and suppress trauma surface infestation, be the ministerial drug in side.Angelica oil anti-inflammatory suppresses mould, and Lavender promotes cell again
Raw wound healing, supplementary drug in the side of being, the effect of aiding in monarch-minister drug.Each taste effect is gentle in side, has no toxic side effect, security
It is high, it is notable to repair trauma effect.
Embodiment
The present invention is described in further detail below by specific examples of the implementation.
Embodiment one
A kind of medicine for repairing skin injury includes the externally dressing consisted of the following composition：By weight, egg yolk oil 20-25
Part, tetratigma hemsleyanum 15-25 parts, Angelica oil 15-20 parts, Lavender 10-15 parts, sesame oil 25-40 parts.
Embodiment two
A kind of medicine for repairing skin injury includes the externally dressing consisted of the following composition：By weight, egg yolk oil 23-25
Part, tetratigma hemsleyanum 15-25 parts, Angelica oil 18-20 parts, Lavender 10-15 parts, sesame oil 25-40 parts.
Embodiment three
A kind of medicine for repairing skin injury includes the externally dressing consisted of the following composition：By weight, egg yolk oil 20-25
Part, tetratigma hemsleyanum 20-25 parts, Angelica oil 15-20 parts, Lavender 10-15 parts, sesame oil 30-40 parts.
Example IV
A kind of medicine for repairing skin injury includes the externally dressing consisted of the following composition：By weight, egg yolk oil 20-25
Part, tetratigma hemsleyanum 15-25 parts, Angelica oil 17-20 parts, Lavender 13-15 parts, sesame oil 35-40 parts.
The pharmaceutical formulation of above-described embodiment one to four, every kind of medicinal material can use any part in the range of number, such as in fact
The specific formula shown in example five to 16 is applied, as shown in table 1.But protection scope of the present invention is not limited only to matching somebody with somebody shown in form
Side.
The formula of the medicine for the reparation skin injury that the embodiment five to 16 of table 1 provides
The medicine of the reparation skin injury of above-mentioned all embodiments is by egg yolk oil, tetratigma hemsleyanum, Angelica oil, lavender essence
The Chinese medicine of five kinds of medicinal material compositions of oil and sesame oil, it has good therapeutic effect to various degrees of skin injury, especially
There is unique curative effect to deep two degree of skin traumas, unique curative effect is mainly reflected in：
One, direct external application can treat, and without carrying out skin grafting, greatly alleviate patient's physiology and psychological pain
It is bitter.It is proposed with following applicating method：After medical dressing is impregnated with this decoction, the surface of a wound, dosage and application number are spread on
To keep the surface of a wound to have decoction moistening for principle.
Two, treatment cycle is short, clinical tests prove that, with the deep two degree of skins of drug therapy of the reparation skin injury of the present invention
It during skin wound, can fully recover within 2-3 weeks, be shortened at least 10-30 days relative to traditional skin grafting course for the treatment of.
Three, it can relieve pain, anti-inflammation, protect the surface of a wound not infected, wound healing, so as to significantly inhibit scar
Formation and hyperplasia, reproducibility reparation is carried out to skin.
Four, have no side effect safely, the tissue such as counterpart eye mucosa is non-stimulated, and all materials are edible material, no use
Taboo.
Five, treatment procedure is simple, and expense is low.
Six, alternative Iodophor directly acts on the anti-inflammation of damaged tissues, can effectively suppress the wound of larger area
Infection, repair because delay treatment has infected the surface of a wound of suppuration；And traditional iodophor disinfection entrance eye can cause burn, few portion
People is divided to cause dry skin, highly concentrated solution to Iodophor allergy, long-term use（Such as 0.5% Iodophor）Have pigmentation phenomenon,
Being hardened etc. stimulates phenomenon.
Seven, in addition to critical wound, anti-infective process, i.e. medicine of the invention can be individually completed without other ancillary drugs
The alternative traditional antibiotic completion of thing is anti-infective, and avoids drug resistance and toxic side effect.
The effect of each medicinal material is as follows in the medicine of the reparation skin injury of above-mentioned all embodiments.
Egg yolk oil has the function that heat-clearing moisturizing, anti-inflammatory analgetic, convergence myogenic and protection sore face.
There is Angelica oil anti-inflammatory to handle mould effect.
Tetratigma hemsleyanum is the exclusive swag Wild Medicinal in China, cool in nature, sweet, have no toxic side effect, China people
Between it is often outer be used to control venomous snake bite, skin cellulitis, traumatic injury, there is clearing heat and detoxicating, antimicrobial and anti-inflammation efficacy（《Plant name
Real figure is examined》Record：Traumatic injury is controlled, married woman's irregular menstruation, applies all nameless sores or boils；《Guangxi practicality Chinese herbal medicine newly selects》Record：
Promoting blood circulation to remove blood stasis, strengthen the bone, control traumatic injury, lumbago due to wind-wetness evil, furuncle, eczema；《Zhejiang conventional herbal medicine among the people》Record：Refrigerant solution
Poison, dispelling pathogenic wind and eliminating phlegm）.
Lavender can promote cytothesis, help wound healing.
Sesame oil has removing toxic substances, moisturized, the work(of myogenic, fragrant odour, is apt to walk to alter, and can be used as carrier by various active ingredients
Hypodermis is penetrated into, plays three effects：1st, detoxify and moisturize myogenic；2nd, replenishing qi and blood filling liver kidney；3rd, fragrant odour, it is kind to walk to alter thoroughly,
Priming is to sick institute（《Japan hanako materia medica》Record：Myogenic is put on flesh, analgesic, subduing inflammation, is mended skin and is split）.
The compatibility principle of the medicine of the reparation skin injury of above-mentioned all embodiments is：Egg yolk oil is warm-natured, has detumescence solution
Poison, the effect of expelling pus and promoting granulation, matching with sesame oil can relieve pain, restrain the surface of a wound, reduces body fluid and oozes out, wound healing, sesame
Sesame oil is with egg yolk oil and is the monarch drug in a prescription in side, is mainly used to the hemostasis and pain-relieving of wound, injected organism tissue reparation, suppresses scar hyperplasia；Three
Rattan is climbed on leaf precipice, has clearing heat and detoxicating, outer to be used to controlling venomous snake bite, cellulitis, traumatic injury, and tetratigma hemsleyanum coordinates monarch drug in a prescription to use
Disinfected in anti-inflammatory and suppress trauma surface infestation, be the ministerial drug in side.Angelica oil anti-inflammatory suppresses mould, and Lavender promotes cytothesis
Wound healing, supplementary drug in the side of being, the effect of aiding in monarch-minister drug.Each taste effect is gentle in side, has no toxic side effect, security pole
Height, it is notable to repair trauma effect.
Embodiment 17
The medicine of the reparation skin injury of all the above embodiment can use following preparation method, comprise the following steps：
The first step：Sesame oil is heated to 50-75 DEG C.
Second step：Tetratigma hemsleyanum is added into the sesame oil after heating, then sesame oil is kept 60- at 50-75 DEG C
90min, obtain the first mixture.
3rd step：First mixture is filtered, obtains filtrate.
4th step：Angelica oil, Lavender and egg yolk oil are added into filtrate, and is stirred, obtains product.
In the above method, the first step and second step will have under conditions of heating and insulation with sesame oil in tetratigma hemsleyanum
Effect composition fully extracts, then the filtering by the 3rd step removes the impurity such as the caused dregs of a decoction after extraction, is eventually adding surplus
Three remaining taste medicinal materials（Return oil, Lavender and egg yolk oil）, you can obtain repairing the medicine of skin injury.
Heating-up temperature -50-75 DEG C in the first step and second step belongs to low temperature extraction, also may be used in actual fabrication process
To adjust, not destroy the nutritional ingredient in medicinal material as limitation, after heating-up temperature adjustment, soaking time（That is extraction time）Also need
It is adjusted accordingly, for example with the temperature extraction higher than 75 DEG C, extraction time can accordingly shorten.
The filtering of 3rd step preferably uses the membrane filtration of 200 mesh, research has shown that, the impurity in decoction is less than 200 mesh
When to wound tissue without negative impact.
In order that all medicinal materials can be sufficiently mixed, interpenetrate, it is preferable that add Angelica oil, Lavender and
The filtrate is first heated to 50-75 DEG C before egg yolk oil, i.e., surplus materials is added in the environment of 50-75 DEG C.And add
The mode of Angelica oil, Lavender and egg yolk oil will not have an impact to the therapeutic effect of product, therefore can use any side
Formula adds, for example, mode one, while add Angelica oil, Lavender and egg yolk oil；Mode two, it is separately added into Angelica oil, smokes
Clothing grass essential oil and egg yolk oil, and the sequencing of three does not have specific limitation.
In addition, the medicine that above-described embodiment 17 is only the reparation skin injury of the present invention provides one of preparation method,
In practical application, also it can use other customary preparation methods that the medicine of the present invention is made, and can equally reach institute above
The technique effect stated.For example, it can first use one or more oily heating extractions in Angelica oil, Lavender and egg yolk oil
Tetratigma hemsleyanum, then filter successively, add remaining medicinal material；Or with sesame oil and Angelica oil, Lavender and egg yolk oil
Any one or more combination after heating extraction tetratigma hemsleyanum, then filter successively, add remaining medicinal material.
In order to illustrate more clearly of the effect of the present invention, clinical example also provided below, it is specific as shown in table 2.
Remarks：The reason for " take a turn for the better discharge " in table 2 is mostly that patient home is in and considers saving expense, steady in the condition of the injury
Discharge is required after fixed, the big portion's healing of the surface of a wound.Treatment method during in hospital is the medicine of the reparation skin injury of the application present invention
Thing.
As shown in Table 2, the present invention has good therapeutic effect to II ° of-III ° of skin injury, and treatment cycle is shorter, puts down
I.e. improvement in about 17 days can leave hospital or fully recover.
The clinical treatment example of table 2
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.Within the spirit and principles of the invention, that is made any repaiies
Change, equivalent substitution, improvement etc., should be included in the scope of the protection.
Claims (7)
1. repair the medicine of skin injury, it is characterised in that the externally dressing consisted of the following composition：By weight, egg yolk oil 20-
25 parts, tetratigma hemsleyanum 15-25 parts, Angelica oil 15-20 parts, Lavender 10-15 parts, sesame oil 25-40 parts；
The medicine for repairing skin injury is made by following methods：
Step A：The sesame oil is heated to 50-75 DEG C；
Step B：The tetratigma hemsleyanum is added into the sesame oil after heating, then makes the sesame oil at 50-75 DEG C
60-90min is kept, obtains the first mixture；
Step C：First mixture is filtered, obtains filtrate；
Step D：The Angelica oil, the Lavender and the egg yolk oil are added into the filtrate, and is stirred, is produced
Product.
2. the medicine according to claim 1 for repairing skin injury, it is characterised in that by weight, egg yolk oil 23-25
Part, tetratigma hemsleyanum 15-25 parts, Angelica oil 18-20 parts, Lavender 10-15 parts, sesame oil 25-40 parts.
3. the medicine according to claim 1 for repairing skin injury, it is characterised in that by weight, egg yolk oil 20-25
Part, tetratigma hemsleyanum 20-25 parts, Angelica oil 15-20 parts, Lavender 10-15 parts, sesame oil 30-40 parts.
4. the medicine according to claim 1 for repairing skin injury, it is characterised in that by weight, egg yolk oil 20-25
Part, tetratigma hemsleyanum 15-25 parts, Angelica oil 17-20 parts, Lavender 13-15 parts, sesame oil 35-40 parts.
5. the medicine according to claim 1 for repairing skin injury, it is characterised in that the method for the filtering is：With 200
Purpose membrane filtration.
6. the medicine according to claim 1 for repairing skin injury, it is characterised in that in step D, add into the filtrate
Before entering Angelica oil, Lavender and egg yolk oil, in addition to：The filtrate is first heated to 50-75 DEG C.
7. the medicine according to claim 1 for repairing skin injury, it is characterised in that in step D, add into the filtrate
Following either type can be used by entering Angelica oil, Lavender and egg yolk oil：
Mode one, while add Angelica oil, Lavender and egg yolk oil；
Mode two, it is separately added into Angelica oil, Lavender and egg yolk oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410154749.1A CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410154749.1A CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
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| Publication Number | Publication Date |
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| CN103893422A CN103893422A (en) | 2014-07-02 |
| CN103893422B true CN103893422B (en) | 2018-02-09 |
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| CN201410154749.1A Active CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
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| CN104784267B (en) * | 2015-04-23 | 2017-11-03 | 杜平全 | It is a kind of to treat medicine oil of burn and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1493316A (en) * | 2002-10-29 | 2004-05-05 | 魏汉东 | Medicinal composition for treating burn and its preparation process |
| CN1723953A (en) * | 2005-07-08 | 2006-01-25 | 胡馨尹 | Herb medicine |
| CN101417027A (en) * | 2008-11-07 | 2009-04-29 | 肖建勋 | Health-care paste of treatment burn scar and preparation method thereof |
-
2014
- 2014-04-17 CN CN201410154749.1A patent/CN103893422B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1493316A (en) * | 2002-10-29 | 2004-05-05 | 魏汉东 | Medicinal composition for treating burn and its preparation process |
| CN1723953A (en) * | 2005-07-08 | 2006-01-25 | 胡馨尹 | Herb medicine |
| CN101417027A (en) * | 2008-11-07 | 2009-04-29 | 肖建勋 | Health-care paste of treatment burn scar and preparation method thereof |
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| CN103893422A (en) | 2014-07-02 |
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Effective date of registration: 20190410 Address after: 330002 Jiangdong Residential Area, 756 Jinggangshan Avenue, Qingyunpu District, Nanchang City, Jiangxi Province, 18 Patentee after: Zhang Guojin Address before: 330000 Room 101, Room 3, Building 35, Unit 101, Section 2, Xiangyihua City, Qingshan Lake District, Nanchang City, Jiangxi Province, No. 1269, Hubin East Road, Qingshan Lake District (1st floor) Patentee before: Jiangxi Xiang Run Science and Technology Ltd. |