CN1493316A

CN1493316A - Medicinal composition for treating burn and its preparation process

Info

Publication number: CN1493316A
Application number: CNA021395055A
Authority: CN
Inventors: 魏汉东
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-10-29
Filing date: 2002-10-29
Publication date: 2004-05-05
Anticipated expiration: 2022-10-29
Also published as: CN1257738C

Abstract

A Chinese medicine in the form of ointment for treating burn and scald is prepared from 11 Chinese-medicinal materials including arnebia root, Chinese angelica root, honeysuckle stem, borneol, etc. through flushing, grinding, fusing, extracting and preparing ointment. Its advantage is high curative effect.

Description

The pharmaceutical composition and the preparation technology thereof of treatment burn

Technical field

The invention belongs to a kind of preparation for the treatment of the burn external.

Background technology

Chinese medicine and pharmacy is great historical treasure-house, and the Chinese medicine burn has the long history in more than 2,000 year.For a long time, the form of Chinese drug of external curing burn has multiple dosage forms such as the powder that comprises unguentum, membrane, decoction, the third fourth agent, aerosol.According to domestic literature, utilizations such as Wang Jingshan have the effect of clearing away heat and cooling blood, detoxification and sores, promoting blood circulation and stopping pain, dampness convergence from the side's of plan red rice cream (containing Cortex Phellodendri, Caulis Lonicerae, Radix Arnebiae (Radix Lithospermi), Pericarpium Papaveris etc.), analgesic effect is obvious, can accelerate epithelial growth speed, reduce and ooze out and infection chance, have no side effect.The high application of Zhu Yong " dragon and tiger water hinder oil " (being made up of Pheretima, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Borneolum Syntheticum etc.), this medical instrument has the protection wound surface, protects from infection, promotes wound surface to heal as early as possible and reduce effect such as cicatrization.

Summary of the invention

Purpose of the present invention is intended to the principle-method-recipe-medicines of Research on Mining Chinese medicine burn, sum up clinical experience for many years, on the basis of a large amount of tests, developed a kind of Chinese medicine ointment, has removing heat from blood and promoting blood circulation, anti-inflammatory analgesic, blood stasis dispelling toxin expelling, putrefaction-removing granulation-promoting, the effect of promotion tissue regeneration, for treatment burn, scald, chemical burn, electric injury and the disunion of a specified duration of wound postoperative infection all have obvious curative effects.

The object of the present invention is achieved like this

A kind of pharmaceutical composition for the treatment of burn, its component and content are:

Radix Arnebiae (Radix Lithospermi) 20-30g Radix Et Rhizoma Rhei 20-30g Radix Angelicae Dahuricae 20-30g Cortex Phellodendri 15-20g

Radix Angelicae Sinensis 10-20g Caulis Lonicerae 10-20g Sanguis Draxonis 5-10g Borneolum Syntheticum 5-10g

Egg oil 50-60g Cera Flava 40-50g Oleum Sesami 500-600g

A kind of pharmaceutical composition for the treatment of burn, its preparation method is:

(1) Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, Radix Et Rhizoma Rhei, Caulis Lonicerae, Radix Angelicae Sinensis, selected back weighing is the same, clean with distilled water flushing, run through, put standby.

(2) Borneolum Syntheticum, Sanguis Draxonis are ground impalpable powder respectively and cross 120 mesh sieves.

(3) Cera Flava is added the boiled water heating and melting and filter, standby after staticizing.

(4) preparation of egg oil: egg is boiled, isolate egg yolk after the cooling, put in the pot and fry, isolate fluid, filter standby to fuel-displaced.

(5) lixiviate medicinal liquid: Oleum Sesami 500-600g is put when heating in the iron pan earlier to 80-90 ℃, add Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, Cortex Phellodendri, the Radix Angelicae Dahuricae respectively, the slow fire lixiviate, make when adding medicine to into buff medicine is pulled out, add Caulis Lonicerae then, add at last Radix Arnebiae (Radix Lithospermi) slowly lixiviate closely pull medicinal residues out to burnt brown, filter standby.

(6) system cream: egg oil, Cera Flava entered to heat in the medicine oil to Cera Flava all melt, refilter mixed liquor, and constantly stir when treating oily temperature drop to 35-45 ℃, add Sanguis Draxonis earlier, add Borneolum Syntheticum powder again, constantly be stirred to evenly, the cooling canned ointment box packing in back is standby.

Medicine character: be the brownish red ointment

Quality standard: meet " Chinese pharmacopoeia version ointment in 2000 quality standard project pertinent regulations.

The beneficial effect of advantage of the present invention and generation is:

1, have removing heat from blood, invigorate blood circulation, skin is given birth in blood stasis dispelling, anti-inflammatory analgetic, accent flesh, promote the function of tissue regeneration; protect wound surface simultaneously in addition; form a wound repair barrier; do not make the wound surface loss of moist; the physiological environment that formative tissue is repaired; can also make burn wound's slough liquefaction drain unobstructed, bacteria growing inhibiting is bred, and has protected the regeneration function of wound tissue cell to greatest extent.

2, be applicable to a variety of causes and the burn that causes, scald, chemical burn, electric injury, wound and wound surface infect and do not close up for a long time, the deep ulcer wound surface of long-term disunion, and have prevention of scar to form, the effect of skin whitening.

3, the present invention handles through burn wound: ointment is coated onto on the wound surface thick 1-1.5mm; Hinder the back 1-5 days, and dabbed ointment every day once; Every day, coating was 2-4 time; Hinder back about 5-15 days; edema wound disappears; the slough liquefaction of wound surface surface; have faint yellow secretions to overflow outside wound surface ointment layer, wipe secretions once with cotton swab this every day phase, and then unction; it is histiocyte regeneration protecting film that 10-15 days left and right sides outer face surface form white mantle; this film comes off in therapeutic process voluntarily, does not wipe by force, still adheres to the wound surface coating.For dark II degree, shallow III degree burn, 10-25 days left and right sides coatings of wound surface process, wound tissue cell and corium to regenerate reparation, wound healing forms scarlet tender skin, applies ointment more on a small quantity about 10 days, so that the wound surface skin aging, wound surface heals fully.Since the nineteen ninety-five applying clinical, burn patient 289 people have been treated altogether, cure rate 100%.

The specific embodiment

A kind of pharmaceutical composition for the treatment of burn, contain:

Radix Arnebiae (Radix Lithospermi) 20g Radix Et Rhizoma Rhei 20g Radix Angelicae Dahuricae 20g Cortex Phellodendri 15g

Radix Angelicae Sinensis 20g Caulis Lonicerae 20g Sanguis Draxonis 5g Borneolum Syntheticum 5g

Egg oil 50g Cera Flava 40g Oleum Sesami 500g

A kind of pharmaceutical composition for the treatment of burn, its preparation technology's flow process:

(5) lixiviate medicinal liquid: earlier Oleum Sesami 500g is put when heating to 90 ℃ in the iron pan, add Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, Cortex Phellodendri, the Radix Angelicae Dahuricae respectively, the slow fire lixiviate, make when adding medicine to into buff medicine is pulled out, add Caulis Lonicerae then, add at last Radix Arnebiae (Radix Lithospermi) slowly lixiviate pull medicinal residues out to burnt brown, filter standby.

(6) system cream: egg oil, Cera Flava entered to heat in the medicine oil to Cera Flava all melt, refilter mixed liquor, and constantly stir when treating oily temperature drop to 40 ℃, add Sanguis Draxonis earlier, add Borneolum Syntheticum powder again, constantly be stirred to evenly, the cooling canned ointment box packing in back is standby.

Ointment evenly is coated with disinfecting cotton swab touches on the wound surface about the thick 1mm of reaching, every day 2-4 time, expose wound surface, but it is thick to be difficult for exposure portion and deep wound infections unction 2-3mm, cover wrapping with the layer 2-3 antiseptic gauze, every day, coating was 1-2 time, or made ointment ribbon gauze and cover on the wound surface, change dressings 1-2 every day, up to wound healing.

Claims

1, a kind of pharmaceutical composition for the treatment of burn, contain:

Egg oil 50-60g Cera Flava 40-50g Oleum Sesami 500-600g

2, a kind of preparation of pharmaceutical compositions technology for the treatment of burn is characterized in that:

(5) lixiviate medicinal liquid: Oleum Sesami 500-600g is put when heating in the iron pan earlier to 80-90 ℃, add Radix Angelicae Sinensis, Radix Et Rhizoma Rhei, Cortex Phellodendri, the Radix Angelicae Dahuricae respectively, the slow fire lixiviate, make when adding medicine to into buff medicine is pulled out, add Caulis Lonicerae then, add at last Radix Arnebiae (Radix Lithospermi) slowly lixiviate pull medicinal residues out to the burnt brown, filter standby.