CN103893422A - Drug for repairing skin injury and preparation method of drug - Google Patents
Drug for repairing skin injury and preparation method of drug Download PDFInfo
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- CN103893422A CN103893422A CN201410154749.1A CN201410154749A CN103893422A CN 103893422 A CN103893422 A CN 103893422A CN 201410154749 A CN201410154749 A CN 201410154749A CN 103893422 A CN103893422 A CN 103893422A
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Abstract
The invention relates to the field of a traditional Chinese medicine, and particularly relates to a drug for repairing a skin injury and a preparation method of the drug. The drug comprises a topical agent prepared from the following components in parts by weight: 20-25 parts of egg yolk oil, 15-25 parts of tetrastigma hemsleyanum, 15-20 parts of angelica oil, 10-15 parts of lavender essential oil and 25-40 parts of sesame oil. The drug for repairing the skin injury has good treatment effects on various degrees of skin injuries, and especially has a unique curative effect on deep second skin trauma. The curative effect is mainly reflected as follows: the skin injury can be cured by direct external application, does not need skin grafting, and is short in treatment cycle. The clinical test proves that the deep second skin trauma can be cured after 2-3 weeks when being treated by using the drug for repairing the skin injury. Compared with the traditional skin grafting, the treatment course is shortened by at least 10-30 days, and the drug can be used for stopping pain, resisting bacteria and diminishing inflammation, protecting the wound from being polluted, promoting wound healing, and carrying out reducing repairing on the skin, and is safe and free of a side effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to repairing medicine of skin injury and preparation method thereof.
Background technology
Skin is one very important barrier of human body, both can prevent the loss of moisture, electrolyte and other material nutrition material in body, can stop again the intrusion of extraneous harmful substance.In addition, skin also directly affects the attractive in appearance of people.As can be seen here, the health degree of skin is most important to human body.
In correlation technique, the medicine of repairing skin injury is varied, comprise Chinese medicine and Western medicine, but these medicines generally can only be treated skin minor trauma, and larger for dark two degree (being depthⅡ°) skin trauma difficulty.At present, be skin grafting for the conventional a kind of Therapeutic Method of dark two degree skin trauma, there is following technical disadvantages in skin grafting: treatment flow process complexity, depends on surgical surgical technic; Patient physiological and psychological misery are strengthened; Medical expense costliness.
Summary of the invention
The object of the present invention is to provide medicine of repairing skin injury and preparation method thereof, to solve the above problems.
A kind of medicine of repairing skin injury is provided in an embodiment of the present invention, comprise the externally dressing consisting of the following composition: by weight, elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
Further, by weight, elgen 23-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 18-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
Further, by weight, elgen 20-25 part, tetratigma hemsleyanum 20-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 30-40 part.
Further, by weight, elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 17-20 part, Herba Lysimachiae foenum-graeci quintessence oil 13-15 part, Oleum sesami 35-40 part.
The preparation method that the medicine of above-mentioned reparation skin injury is also provided in an embodiment of the present invention, comprises the following steps:
Steps A: Oleum sesami is heated to 50-75 DEG C;
Step B: add tetratigma hemsleyanum in the Oleum sesami after heating, then make Oleum sesami keep 60-90min at 50-75 DEG C, obtain the first mixture;
Step C: the first mixture is filtered, obtain filtrate;
Step D: add Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen in filtrate, and stir, obtain product.
Further, the method for filtration is: with 200 object membrane filtrations.
Further, in step D, before adding Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen in filtrate, also comprise: first filtrate is heated to 50-75 DEG C.
Further, in step D, in filtrate, add Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen can adopt following either type:
Mode one adds Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen simultaneously;
Mode two, adds respectively Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen.
The Chinese medicine that the medicine of the reparation skin injury of the above embodiment of the present invention is made up of elgen, tetratigma hemsleyanum, Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and five kinds of medical materials of Oleum sesami, it all has good therapeutic effect to the skin injury of various degree, especially dark two degree skin traumas are had to unique curative effect, this uniqueness curative effect is mainly reflected in: one, directly external application can be treated, without carrying out skin grafting, patient physiological and psychological misery are greatly alleviated; Two, treatment cycle is short, proves through clinical trial, and during with the dark two degree skin trauma of the Drug therapy of reparation skin injury of the present invention, 2-3 week can fully recover, and has at least shortened 10-30 days the course for the treatment of with respect to traditional skin grafting; Three, can pain relieving, anti-inflammation, protection wound surface is not infected, wound healing, thus significantly suppress formation and the hypertrophy of cicatrix, skin is carried out to reproducibility reparation; Four, safety has no side effect, and boil on the nape opposite the mouth eye mucosa etc. is organized non-stimulated.Five, significantly reduce medical expense.
The formulation principle of the medicine of the reparation skin injury of the above embodiment of the present invention is: elgen is warm in nature, there is the effect of subduing swelling and detoxicating, expelling pus and promoting granulation, matching with Oleum sesami can pain relieving, convergence wound surface, reducing body fluid oozes out, wound healing, the monarch drug in Oleum sesami and elgen the side of being, is mainly used to the hemostasis and pain-relieving of wound, when injected organism tissue is repaired, and suppresses scar hyperplasia; Tetratigma hemsleyanum, has heat-clearing and toxic substances removing, outward for controlling venom, and cellulitis, traumatic injury, tetratigma hemsleyanum coordinates monarch drug to suppress traumatic infection for antiinflammatory detoxicating, is the ministerial drug in side.Radix Angelicae Sinensis oil antiinflammatory mould fungus inhibition, Herba Lysimachiae foenum-graeci quintessence oil promotes cell regeneration wound healing, supplementary drug in the side of being, effect of auxiliary monarch-minister drug.In side each taste effect gentle, have no side effect, safety is high, repair trauma effect remarkable.
Detailed description of the invention
Below by specific embodiment, the present invention is described in further detail.
Embodiment mono-
A kind of medicine of repairing skin injury comprises the externally dressing consisting of the following composition: by weight, and elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
Embodiment bis-
A kind of medicine of repairing skin injury comprises the externally dressing consisting of the following composition: by weight, and elgen 23-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 18-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
Embodiment tri-
A kind of medicine of repairing skin injury comprises the externally dressing consisting of the following composition: by weight, and elgen 20-25 part, tetratigma hemsleyanum 20-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 30-40 part.
Embodiment tetra-
A kind of medicine of repairing skin injury comprises the externally dressing consisting of the following composition: by weight, and elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 17-20 part, Herba Lysimachiae foenum-graeci quintessence oil 13-15 part, Oleum sesami 35-40 part.
The pharmaceutical formulation of above-described embodiment one to four, every kind of medical material all can adopt any part within the scope of umber, and for example the concrete formula shown in embodiment five to 16, as shown in table 1.But protection scope of the present invention is not limited only to the formula shown in form.
The formula of the medicine of the reparation skin injury that table 1 embodiment five to 16 provides
The Chinese medicine that the medicine of the reparation skin injury of above-mentioned all embodiment is made up of elgen, tetratigma hemsleyanum, Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and five kinds of medical materials of Oleum sesami, it all has good therapeutic effect to the skin injury of various degree, especially dark two degree skin traumas are had to unique curative effect, this uniqueness curative effect is mainly reflected in:
One, directly external application can be treated, and without carrying out skin grafting, has greatly alleviated patient physiological and psychological misery.Suggestion adopts following applicating method: after medical dressing is soaked in this medicinal liquid, spread on wound surface, dosage and application number of times are to keep wound surface to have medicinal liquid moistening as principle.
Two, treatment cycle is short, proves through clinical trial, and during with the dark two degree skin trauma of the Drug therapy of reparation skin injury of the present invention, 2-3 week can fully recover, and has shortened at least 10-30 days the course for the treatment of with respect to traditional skin grafting.
Three, can pain relieving, anti-inflammation, protection wound surface is not infected, wound healing, thus significantly suppress formation and the hypertrophy of cicatrix, skin is carried out to reproducibility reparation.
Four, safety has no side effect, and boil on the nape opposite the mouth eye mucosa etc. is organized non-stimulated, and all drawing materials is edible material, without using taboo.
Five, treatment procedure is simple, and expense is low.
Six, alternative povidone iodine directly acts on the anti-inflammation of damaged tissues, can effectively suppress the infection of larger area wound, repairs because of the wound surface of infection suppurates of delay treatment; And traditional iodophor disinfection entrance eye can cause burn, a minority is to povidone iodine allergy, life-time service can cause xerosis cutis, highly concentrated solution (as 0.5% povidone iodine) has pigmentation phenomenon, hardening etc. stimulates phenomenon.
Seven, except critical wound, can complete separately infection process without other ancillary drug, the alternative traditional antibiotic of medicine of the present invention completes infection, and has avoided drug resistance and toxic and side effects.
In the medicine of the reparation skin injury of above-mentioned all embodiment, the effect of each medical material is as follows.
Elgen has the effect of heat clearing away skin moistening, anti-inflammatory analgetic, convergence granulation promoting and protection skin ulcer face.
Radix Angelicae Sinensis oil has antiinflammatory and processes mycete effect.
Tetratigma hemsleyanum is the exclusive swag Wild Medicinal of China, cool in nature, sweet in the mouth, have no side effect, China is among the people normal outer for controlling venom, skin cellulitis, traumatic injury, there is heat-clearing and toxic substances removing, antimicrobial and anti-inflammation efficacy (" Zhiwu Mingshi Tukao " record: control traumatic injury, married woman's irregular menstruation, applies all innominate toxic swellings; " the practical Chinese herbal medicine in Guangxi newly selects " recorded: promoting blood circulation to remove blood stasis, and strengthening bone and muscle, controls traumatic injury, lumbago due to pathogenic wind-dampness, furuncle and phyma, eczema; " Zhejiang conventional medical herbs among the people " recorded: refreshing and detoxicating, dispelling pathogenic wind and eliminating phlegm).
Herba Lysimachiae foenum-graeci quintessence oil can promote cell regeneration, helps wound healing.
Oleum sesami has removing toxic substances, moisturizes, the merit of granulation promoting, and fragrant odour, is apt to away alter, and can serve as carrier various effective ingredient are infiltrated to subcutaneous tissue, brings into play three effects: 1, granulation promoting is moisturized in removing toxic substances; 2, replenishing QI and blood invigorating the liver and kidney; 3, fragrant odour, is apt to thoroughly walk to alter, and priming is to sick institute (" Japan hanako materia medica " recorded: granulation promoting is put on flesh, pain relieving, subduing inflammation, benefit rhagades of the skin).
The compatibility principle of the medicine of the reparation skin injury of above-mentioned all embodiment is: elgen is warm in nature, there is the effect of subduing swelling and detoxicating, expelling pus and promoting granulation, matching with Oleum sesami can pain relieving, convergence wound surface, reducing body fluid oozes out, wound healing, the monarch drug in Oleum sesami and elgen the side of being, is mainly used to the hemostasis and pain-relieving of wound, when injected organism tissue is repaired, and suppresses scar hyperplasia; Tetratigma hemsleyanum, has heat-clearing and toxic substances removing, outward for controlling venom, and cellulitis, traumatic injury, tetratigma hemsleyanum coordinates monarch drug to suppress traumatic infection for antiinflammatory detoxicating, is the ministerial drug in side.Radix Angelicae Sinensis oil antiinflammatory mould fungus inhibition, Herba Lysimachiae foenum-graeci quintessence oil promotes cell regeneration wound healing, supplementary drug in the side of being, effect of auxiliary monarch-minister drug.In side each taste effect gentle, have no side effect, safety is high, repair trauma effect remarkable.
Embodiment 17
Above the medicine of the reparation skin injury of all embodiment all can adopt following preparation method, comprises the following steps:
The first step: Oleum sesami is heated to 50-75 DEG C.
Second step: add tetratigma hemsleyanum in the Oleum sesami after heating, then make Oleum sesami keep 60-90min at 50-75 DEG C, obtain the first mixture.
The 3rd step: the first mixture is filtered, obtain filtrate.
The 4th step: add Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen in filtrate, and stir, obtain product.
In said method, the first step and second step fully extract effective ingredient in tetratigma hemsleyanum with Oleum sesami under the condition of heating and insulation, through the filtration of the 3rd step, the impurity such as the medicinal residues that produce after extracting are removed again, finally add remaining three taste medical materials (returning oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen), can obtain repairing the medicine of skin injury.
Heating-up temperature-50-75 in the first step and second step DEG C belongs to extract at low temperature, in actual fabrication process, also can adjust, not destroy nutritional labeling in medical material as restriction, after heating-up temperature is adjusted, temperature retention time (being extraction time) also needs to be adjusted accordingly, for example adopt higher than the temperature of 75 DEG C and extract, extraction time can corresponding shortening.
The filtration of the 3rd step preferably adopts 200 object membrane filtrations, show after deliberation, when the impurity in medicinal liquid is less than 200 order on wound tissue without negative impact.
For all medical materials can fully be mixed, interpenetrate, preferably, before adding Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen, first described filtrate is heated to 50-75 DEG C, under the environment of 50-75 DEG C, add surplus materials.And add the mode of Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen can not exert an influence to the therapeutic effect of product, therefore can adopt any-mode to add, for example, mode one adds Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen simultaneously; Mode two, add respectively Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen, and three's sequencing does not have specific limited.
In addition, above-described embodiment 17 is only one of drug provision preparation method of reparation skin injury of the present invention, in actual applications, also can adopt other conventional preparation method to make medicine of the present invention, and can reach technique effect mentioned above equally.For example, can first adopt one or more the oily heating extraction tetratigma hemsleyanums in Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen, then filter successively, add residue medical material; Or any one in use Oleum sesami and Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen or multiple combination post-heating extract tetratigma hemsleyanum, then filter successively, add residue medical material.
In order to be illustrated more clearly in effect of the present invention, below also provide clinical example, specifically as shown in table 2.
Remarks: the reason of " improvement is left hospital " in table 2 is mostly patient family in considering cost saving, require to leave hospital after, the large portion of wound surface healing stable in traumatic condition.The Therapeutic Method in while in hospital is the medicine of application reparation skin injury of the present invention.
As shown in Table 2, the present invention, to II °-III ° skin injury has good therapeutic effect, and treatment cycle is shorter, takes a turn for the better and can leave hospital or fully recover for average approximately 17 days.
Table 2 clinical treatment example
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (8)
1. the medicine of repairing skin injury, is characterized in that, comprises the externally dressing consisting of the following composition: by weight, and elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
2. the medicine of reparation skin injury according to claim 1, is characterized in that, by weight, and elgen 23-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 18-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 25-40 part.
3. the medicine of reparation skin injury according to claim 1, is characterized in that, by weight, and elgen 20-25 part, tetratigma hemsleyanum 20-25 part, Radix Angelicae Sinensis oil 15-20 part, Herba Lysimachiae foenum-graeci quintessence oil 10-15 part, Oleum sesami 30-40 part.
4. the medicine of reparation skin injury according to claim 1, is characterized in that, by weight, and elgen 20-25 part, tetratigma hemsleyanum 15-25 part, Radix Angelicae Sinensis oil 17-20 part, Herba Lysimachiae foenum-graeci quintessence oil 13-15 part, Oleum sesami 35-40 part.
5. the preparation method of the medicine of reparation skin injury claimed in claim 1, is characterized in that, comprises the following steps:
Steps A: described Oleum sesami is heated to 50-75 DEG C;
Step B: add described tetratigma hemsleyanum in the described Oleum sesami after heating, then make described Oleum sesami keep 60-90min at 50-75 DEG C, obtain the first mixture;
Step C: described the first mixture is filtered, obtain filtrate;
Step D: add described Radix Angelicae Sinensis oil, described Herba Lysimachiae foenum-graeci quintessence oil and described elgen in described filtrate, and stir, obtain product.
6. the preparation method of the medicine of reparation skin injury according to claim 5, is characterized in that, the method for described filtration is: with 200 object membrane filtrations.
7. the preparation method of the medicine of reparation skin injury according to claim 5, is characterized in that, in step D, before adding Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen in described filtrate, also comprises: first described filtrate is heated to 50-75 DEG C.
8. the preparation method of the medicine of reparation skin injury according to claim 5, is characterized in that, in step D, in described filtrate, adds Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen can adopt following either type:
Mode one adds Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen simultaneously;
Mode two, adds respectively Radix Angelicae Sinensis oil, Herba Lysimachiae foenum-graeci quintessence oil and elgen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410154749.1A CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410154749.1A CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN103893422A true CN103893422A (en) | 2014-07-02 |
| CN103893422B CN103893422B (en) | 2018-02-09 |
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| CN201410154749.1A Active CN103893422B (en) | 2014-04-17 | 2014-04-17 | Repair medicine of skin injury and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104784267A (en) * | 2015-04-23 | 2015-07-22 | 杜平全 | Medicinal oil for treating burn and preparation method of medicinal oil |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1493316A (en) * | 2002-10-29 | 2004-05-05 | 魏汉东 | Medicinal composition for treating burn and its preparation process |
| CN1723953A (en) * | 2005-07-08 | 2006-01-25 | 胡馨尹 | Herb medicine |
| CN101417027A (en) * | 2008-11-07 | 2009-04-29 | 肖建勋 | Health-care paste of treatment burn scar and preparation method thereof |
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2014
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1493316A (en) * | 2002-10-29 | 2004-05-05 | 魏汉东 | Medicinal composition for treating burn and its preparation process |
| CN1723953A (en) * | 2005-07-08 | 2006-01-25 | 胡馨尹 | Herb medicine |
| CN101417027A (en) * | 2008-11-07 | 2009-04-29 | 肖建勋 | Health-care paste of treatment burn scar and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104784267A (en) * | 2015-04-23 | 2015-07-22 | 杜平全 | Medicinal oil for treating burn and preparation method of medicinal oil |
| CN104784267B (en) * | 2015-04-23 | 2017-11-03 | 杜平全 | It is a kind of to treat medicine oil of burn and preparation method thereof |
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| Publication number | Publication date |
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| CN103893422B (en) | 2018-02-09 |
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Effective date of registration: 20190410 Address after: 330002 Jiangdong Residential Area, 756 Jinggangshan Avenue, Qingyunpu District, Nanchang City, Jiangxi Province, 18 Patentee after: Zhang Guojin Address before: 330000 Room 101, Room 3, Building 35, Unit 101, Section 2, Xiangyihua City, Qingshan Lake District, Nanchang City, Jiangxi Province, No. 1269, Hubin East Road, Qingshan Lake District (1st floor) Patentee before: Jiangxi Xiang Run Science and Technology Ltd. |