CN101417027A - Health-care paste of treatment burn scar and preparation method thereof - Google Patents
Health-care paste of treatment burn scar and preparation method thereof Download PDFInfo
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- CN101417027A CN101417027A CNA2008102309141A CN200810230914A CN101417027A CN 101417027 A CN101417027 A CN 101417027A CN A2008102309141 A CNA2008102309141 A CN A2008102309141A CN 200810230914 A CN200810230914 A CN 200810230914A CN 101417027 A CN101417027 A CN 101417027A
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Abstract
The invention belongs to burn clinical treatment technical field, its raw material components of health-care paste and the proportioning of the treatment burn scar that proposes are: Semen Impatientis 10～15g, Herba Rosmarini Officinalis 10～15g, Flos Carthami 5～8g, Cortex Moutan 10～20g, Cortex Dictamni 10～20g, Rhizoma Chuanxiong 10～20g, Radix Angelicae Sinensis 10～15g, Galla Chinensis 10～15g, Radix Saposhnikoviae 20～30g, the Fructus Kochiae 10～15g, Oleum lavandula angustifolia 5～8g, Cera Chinensis 20～30g, Oleum Sesami 100～200g, Borneolum Syntheticum 0.5～0.8g.Its preparation method is that crude drug is concocted, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, adding pure water extracts, and will cross cleaner liquid concentrating under reduced pressure, oven dry, superfine powder is handled, and powder and Cera Chinensis are joined in the Oleum Sesami, the mixture cooling is added Borneolum Syntheticum, add Oleum lavandula angustifolia stirring, abundant mix homogeneously again, the paste fill to the PVC flexible pipe, is obtained the health-care paste that the present invention treats burn scar.
Description
Technical field
The invention belongs to burn clinical treatment technical field, mainly propose a kind of health-care paste for the treatment of burn scar and preparation method thereof
Background technology
Burn is generally to mean heating power, comprise hydrothermal solution (hot water, hot soup, deep fat etc.), gas, thunder and lightning, electric shock, chlorine, concentrated acid, highly basic, steam, high-temperature gas, flame, red-hot metal liquid or solid are (as molten steel, steel ingot) etc., caused skin histology infringement, severe patient can injure subcutaneous or (with) mucosa undertissue, as muscle, bone, joint even internal organs, along with the modern industry develop rapidly, the burn that all kinds of heat energy cause grows with each passing day, burn has also just become one of very painful traumatic disease of common but severe harm humans, and is heavy then disable or get killed.
Behind patient's burn,, behind wound healing, have burn scar in various degree because of age size, individual variation, burn surface area size and wound surface depth difference.The essence of burn scar is a kind of do not possess normal skin tissue's structure and physiological function, loses the normal structure vigor, unusual, unsound tissue.Burn scar not only diminishes appearance, also can hinder and the physiological function of linked groups or organ.Some burn scar can develop into proliferative burn scar, has not only not only itched but also pain, the local increase and diffusion, even develop into skin carcinoma.For serious, large-area fire victim, cicatrization causes disfeaturing, dysfunction, and normal work of influence and daily life are so that cause patient's psychological unbalance, spirit depressing.So prevention and treatment burn scar are the important component parts of modern burn treating, the burn scar medicine of determined curative effect can obviously improve the burn-healing quality, reduces disability rate.
Summary of the invention
Purpose of the present invention promptly is to propose a kind of health-care paste for the treatment of burn scar and preparation method thereof, makes it can be to the rehabilitation in fire victim's later stage, and the inhibition of cicatrix, softening, hypertrophy have played excellent curative; Thereby the practical problem that the later stage cicatrix medication shortage of solution burn, uncertain therapeutic efficacy are cut.
Cicatrization and differentiation are the processes of a complexity, when skin injures reticular layer of corium, be organized in the injured first few minutes, there are serum fibrin and sludged blood to occur on the wound surface, after about 24 hours, capillary endothelial cell is grown in sludged blood in the wound surface, form new blood capillary, after 3 days, fibroblast and capillary proliferation, form granulation tissue also gradually the filling of wound chamber, fibroblast begins to stop gradually division in the time of 5～6 days, collagen fiber occur, teleneuron is grown into, and the epithelial cell at wound edge is grown to the center, cover granulation tissue and just formed cicatrix, behind the wound healing in 3 months cicatrix begin to transfer cerise to by pale red, scleroma appears in surperficial roughening, slightly itch bitterly, As time goes on, the hypertrophy aggravation peaked to wound healing approximately in 6 months, scar thickness can reach several millimeters, quality is hard nonelastic, and color transfers purple to by cerise, and surperficial blood capillary appears, be subject to the external force effect and damage, the sufferings symptom is obvious, and to attach most importance to night, it is indecency that joint deformity and dysfunction and outward appearance can appear in cicatricial contracture especially.After burns scar, especially deep burn wound healed voluntarily, how a large amount of hypertrophy of wound surface place skin connective tissue and form hard only regular lump were with the sufferings discomfort.If form keloid and be pertinacious disease in treatment, at present, treat various cicatrixs both at home and abroad and adopt excision, freezing, laser, sealing, the isopressor method of elastic force more than refractory.Facts have proved that curative effect is all undesirable, not only easily recurrence, it is faster, bigger to stimulate cicatrix to make it hypertrophy on the contrary.Along with the like to be beautiful continuous rising of aesthetic conceptions of modern, the problem pendulum of burn, wound scar treatment and research is in face of the medical personnel, and colleague treats the method for all kinds of cicatrixes in tireless discussion both at home and abroad.
The inventor is engaged in the clinical treatment work of burn for a long time, and long term studies has been carried out in the formation of the back cicatrix of burning; Health-care paste of treatment burn scar proposed by the invention and preparation method thereof, be based on theory of Chinese medical science, carry out determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs according to practical situations such as age of patient, occupation, sex, inhabitation regional condition, morbidity seasons, the great achievement and the experience and lessons of burns scar are treated by conscientious research summary hospital over 28 years, break through the key difficult problem of burns scar treatment and medication aspect, with burn naturopathy theoretical system is guidance, promote local drug concentration to raise, suppress scar hyperplasia by the drug transdermal effect; The composing principle of follow Chinese medicinal formulae monarch, minister, helping, make proposes the raw material components and the proportioning of medicine of the present invention: Semen Impatientis 10～15g, Herba Rosmarini Officinalis 10～15g, Flos Carthami 5～8g, Cortex Moutan 10～20g, Cortex Dictamni 10～20g, Rhizoma Chuanxiong 10～20g, Radix Angelicae Sinensis 10～15g, Galla Chinensis 10～15g, Radix Saposhnikoviae 20～30g, the Fructus Kochiae 10～15g, Oleum lavandula angustifolia 5～8g, Cera Chinensis 20～30g, Oleum Sesami 100～200g, Borneolum Syntheticum 0.5～0.8g.
In the raw material components of medicine of the present invention:
Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami is monarch drug, the little hardship of Semen Impatientis wherein, and suffering, temperature, the removing blood stasis softening the hard mass is used for the lump in the abdomen mass in the abdomen.Herba Rosmarini Officinalis has stronger astriction, nurses one's health greasy unclean skin, blood circulation promoting, stimulating hair regeneration.The Flos Carthami promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing.Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong are ministerial drug, and Cortex Moutan contains the former glycoside of Cortex Moutan, paeonol, paeoniflorin, hydroxypaeoniflorin, benzoylpaeoniflorin and volatile oil, and is cold in nature, bitter in the mouth, suffering have clearing away heat and cooling blood, the effect of blood circulation promoting competent silt, be used for maculae caused by violent heat pathogen, carbuncle sore tumefacting virus, fall and pounce on the pain of injury.Shaggy-fruited dittany cold skin, hardship, return spleen, stomach warp, heat clearing and damp drying, the detoxifcation of dispeling the wind.Be used for damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, rheumatism pyretic arthralgia.The Rhizoma Chuanxiong suffering, temperature is returned liver, gallbladder, pericardium channel, has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping, lump in the abdomen stomachache, tumbling and swelling.Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae are adjuvant drug, and having enriches blood invigorates blood circulation expelling pathogenic wind from the body surface; Removing dampness to relieve pain, removing dampness is held back skin ulcer, spasmolytic, effect such as antipruritic.The Fructus Kochiae, Oleum lavandula angustifolia, Cera Chinensis are messenger drug, can remove the damp and hot and ailment said due to cold or exposure in the skin, and itching-relieving efficacies is arranged.Borneolum Syntheticum suffering, hardship are slightly cold.GUIXIN, spleen, the lung hydrocarbon.Have the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain is used for skin infection and swells and ache, and the effect of not holding back after bursting also has heat-clearing and toxic substances removing, erosion prevention and muscle growing effect.The Oleum Sesami nature and flavor are sweet, cool, have the effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.According to putting down in writing on the Compendium of Material Medica: " have moisturize, the merit of detoxifcation, pain relieving, detumescence." do substrate with Oleum Sesami and decoct plaster, also have granulation promoting meat simultaneously, the effect of the pain that relieves the pain.
The preparation method of ointment of the present invention is: with Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami, Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae, the Fructus Kochiae concoct, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, add pure water and make to extract solvent, extract first and add 10～13 times of water gagings, 6～8 times of water gagings of secondary, three 3～5 times of water gagings extract, in 75～90 ℃ of extractions 2.5～3.5 hours, merged 3 times and crossed cleaner liquid at every turn, and with the clear liquid concentrating under reduced pressure; Concentrated extract is dried, superfine powder is handled, powder to 180～240 orders joins above-mentioned powder and Cera Chinensis in 90～120 ℃ the Oleum Sesami, stirs, add Borneolum Syntheticum when then mixture being cooled to 48～55 ℃, when stirring is cooled to 32～38 ℃, adds Oleum lavandula angustifolia again and stirred 22～26 hours, fully mix homogeneously, above-mentioned paste fill to the PVC flexible pipe, is put in storage product inspection irradiation.
The using method of ointment of the present invention:
1, external, behind the wound healing, cicatrix does not form preceding or the cicatrization initial stage, the burn antibacterial liquid (applying for a patent in addition) that uses the inventor to propose will heal wipe away after wound surface cleans up dried, it is thick that ointment of the present invention evenly is applied to the about 1～2mm in affected part, and in addition appropriateness massage 5～10 minutes, helps drug absorption, every day 3～5 times, 3 months is a course of treatment.
2, wound healing can be used, medication more early, and curative effect is good more, and treatment cycle is short more, and continuous use effect 2 courses of treatment is better.
3, cicatrix has formed or the cicatrix later stage, be under the specialist instruct, and according to situations such as the position of scar hyperplasia and complication, cooperate method such as functional exercise to carry out Comprehensive Treatment.
4, during using the cicatrix health-care paste, avoid ichthyophagy, shrimp, suffering, the food that stimulates such as peppery.
5, the autopath avoids usefulness.
In the prescription of the present invention, compositions such as any Western medicine and hormone cannot be added, otherwise the curative effect of former medicine can be lost.
Ointment of the present invention is through a large amount of clinical verifications, and behind wound healing, cicatrix does not form preceding or the cicatrization initial stage uses, and is evident in efficacy, can play softening, inhibition cicatrix, reduces the effect of pigmentation, prevents scar contracture and reduces odd-shaped generation.Ointment of the present invention is applied in skin surface, make medicine quick penetration skin surface enter skin corium, form the connective tissue of cicatrix before decomposing, reparation broken fiber tissue, recover the collagen structure of skin basal layer, make its proper alignment, keep level and smooth and gloss, elasticity and the toughness of skin, treat various types of burn scar, and the various cicatrixs that form of operation, wound later stage.Has following function: the function of blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, removing toxic substances and promoting subsidence of swelling, software eliminating stagnation, inhibition scar hyperplasia, alleviation cicatrix pruritus, softening cicatrix.
The clinical therapeutic efficacy of ointment of the present invention is in particular in: this product is through a large amount of clinical verifications, and is safe in utilization, without any side effects; The early stage use of cicatrix can be played softening cicatrix, alleviates the uncomfortable sensations such as sufferings of cicatrix; To the cicatrix that has formed, can protect cicatrix skin effectively, improve partial microcirculation, the tight bundle sense behind the alleviation cicatrix, the reparation of vesicle behind the promotion cicatrix, the hypertrophy rate of reduction cicatrix, patient's quality of life behind the raising burn-healing.
The present invention is a pure Chinese medicinal preparation, the finished product price is on the low side, can allow more fire victim obtain correct treatment in time, and can save medical care expenses and Operation Fee about 50%, make the patient can get back to the work of going in the society early, improved patient's self-confidence, also made contribution for building a harmonious society.
Description of drawings
Fig. 1 is the process chart of the present invention's preparation.
The specific embodiment
Provide embodiments of the invention, but do not constitute any limitation of the invention:
Embodiment 1:
The raw material components of medicine of the present invention and proportioning are: Semen Impatientis 10g, Herba Rosmarini Officinalis 13g, Flos Carthami 8g, Cortex Moutan 10g, Cortex Dictamni 20g, Rhizoma Chuanxiong 15g, Radix Angelicae Sinensis 10g, Galla Chinensis 13g, Radix Saposhnikoviae 20g, Fructus Kochiae 15g, Oleum lavandula angustifolia 7g, Cera Chinensis 30g, Oleum Sesami 150g, Borneolum Syntheticum 0.5g.
The preparation method of ointment of the present invention is: with Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami, Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae, the Fructus Kochiae concoct, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, add pure water and make to extract solvent, extract first and add 10 times of water gagings, 8 times of water gagings of secondary, three 3 times of water gagings extract, in 85 ℃ of extractions 3.5 hours, merged 3 times and crossed cleaner liquid at every turn, and with the clear liquid concentrating under reduced pressure; Concentrated extract is dried, superfine powder is handled, powder to 200 order joins above-mentioned powder and Cera Chinensis in 100 ℃ the Oleum Sesami, stirs, add Borneolum Syntheticum when then mixture being cooled to 50 ℃, when stirring is cooled to 32 ℃, adds Oleum lavandula angustifolia again and stirred 24 hours, fully mix homogeneously, above-mentioned paste fill to the PVC flexible pipe, is put in storage product inspection irradiation.
Embodiment 2:
The raw material components of this embodiment medicine and proportioning are: Semen Impatientis 15g, Herba Rosmarini Officinalis 10g, Flos Carthami 5g, Cortex Moutan 15g, Cortex Dictamni 15g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 15g, Galla Chinensis 10g, Radix Saposhnikoviae 30g, Fructus Kochiae 13g, Oleum lavandula angustifolia 5g, Cera Chinensis 20g, Oleum Sesami 200g, Borneolum Syntheticum 0.8g.
The preparation method of ointment of the present invention is: with Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami, Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae, the Fructus Kochiae concoct, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, add pure water and make to extract solvent, extract first and add 12 times of water gagings, 7 times of water gagings of secondary, three 5 times of water gagings extract, in 90 ℃ of extractions 3 hours, merged 3 times and crossed cleaner liquid at every turn, and with the clear liquid concentrating under reduced pressure; Concentrated extract is dried, superfine powder is handled, powder to 240 order joins above-mentioned powder and Cera Chinensis in 120 ℃ the Oleum Sesami, stirs, add Borneolum Syntheticum when then mixture being cooled to 55 ℃, when stirring is cooled to 36 ℃, adds Oleum lavandula angustifolia again and stirred 26 hours, fully mix homogeneously, above-mentioned paste fill to the PVC flexible pipe, is put in storage product inspection irradiation.
Embodiment 3:
The raw material components of this embodiment Chinese medicine and proportioning are: Semen Impatientis 13g, Herba Rosmarini Officinalis 15g, Flos Carthami 6g, Cortex Moutan 20g, Cortex Dictamni 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Sinensis 12g, Galla Chinensis 15g, Radix Saposhnikoviae 25g, Fructus Kochiae 10g, Oleum lavandula angustifolia 8g, Cera Chinensis 25g, Oleum Sesami 100g, Borneolum Syntheticum 0.6g.
The preparation method of ointment of the present invention is: with Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami, Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae, the Fructus Kochiae concoct, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, add pure water and make to extract solvent, extract first and add 13 times of water gagings, 6 times of water gagings of secondary, three 4 times of water gagings extract, in 75 ℃ of extractions 2.5 hours, merged 3 times and crossed cleaner liquid at every turn, and with the clear liquid concentrating under reduced pressure; Concentrated extract is dried, superfine powder is handled, powder to 180 order joins above-mentioned powder and Cera Chinensis in 90 ℃ the Oleum Sesami, stirs, add Borneolum Syntheticum when then mixture being cooled to 48 ℃, when stirring is cooled to 38 ℃, adds Oleum lavandula angustifolia again and stirred 22 hours, fully mix homogeneously, above-mentioned paste fill to the PVC flexible pipe, is put in storage product inspection irradiation.
Claims (2)
1, a kind of health-care paste for the treatment of burn scar, it is characterized in that: the raw material components of medicine of the present invention and proportioning are: Semen Impatientis 10～15g, Herba Rosmarini Officinalis 10～15g, Flos Carthami 5～8g, Cortex Moutan 10～20g, Cortex Dictamni 10～20g, Rhizoma Chuanxiong 10～20g, Radix Angelicae Sinensis 10～15g, Galla Chinensis 10～15g, Radix Saposhnikoviae 20～30g, the Fructus Kochiae 10～15g, Oleum lavandula angustifolia 5～8g, Cera Chinensis 20～30g, Oleum Sesami 100～200g, Borneolum Syntheticum 0.5～0.8g.
2, a kind of method for preparing right 1 treatment burn scar health-care paste, it is characterized in that: with Semen Impatientis, Herba Rosmarini Officinalis, Flos Carthami, Cortex Moutan, Cortex Dictamni, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Galla Chinensis, Radix Saposhnikoviae, the Fructus Kochiae concoct, make the prepared slices of Chinese crude drugs in the Chinese medicine extraction device, add pure water and make to extract solvent, extraction first adds 10～13 times of water gagings, and 6～8 times of water gagings of secondary, three 3～5 times of water gagings extract, and extract 2.5～3.5 hours in 75～90 ℃ at every turn, merge 3 times and cross cleaner liquid, and with the clear liquid concentrating under reduced pressure; Concentrated extract is dried, superfine powder is handled, powder to 180～240 orders joins above-mentioned powder and Cera Chinensis in 90～120 ℃ the Oleum Sesami, stirs, add Borneolum Syntheticum when then mixture being cooled to 48～55 ℃, when stirring is cooled to 32～38 ℃, adds Oleum lavandula angustifolia again and stirred 22～26 hours, fully mix homogeneously, above-mentioned paste fill to the PVC flexible pipe, is obtained the health-care paste that the present invention treats burn scar.
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| CNA2008102309141A CN101417027A (en) | 2008-11-07 | 2008-11-07 | Health-care paste of treatment burn scar and preparation method thereof |
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| CNA2008102309141A CN101417027A (en) | 2008-11-07 | 2008-11-07 | Health-care paste of treatment burn scar and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893479A (en) * | 2014-03-21 | 2014-07-02 | 杨孝良 | Ointment for treating empyrosis and preparation method thereof |
| CN103893422A (en) * | 2014-04-17 | 2014-07-02 | 江西祥润科技有限公司 | Drug for repairing skin injury and preparation method of drug |
| CN104042560A (en) * | 2014-07-08 | 2014-09-17 | 福州绿野生化技术有限公司 | Scar removing liquid containing astragaloside and preparation method of scar removing liquid |
| CN105055768A (en) * | 2015-07-07 | 2015-11-18 | 中国人民解放军第四军医大学 | Traditional Chinese medicine compound external-application preparation for treating cicatrix and preparation method and application thereof |
| RU2651057C1 (en) * | 2016-10-26 | 2018-04-18 | Сергей Борисович Богданов | Method of application of vacuum dressing to head |
| RU2655832C2 (en) * | 2016-10-31 | 2018-05-29 | Сергей Борисович Богданов | Method of surgical treatment of patients with total scar facial deformities |
-
2008
- 2008-11-07 CN CNA2008102309141A patent/CN101417027A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893479A (en) * | 2014-03-21 | 2014-07-02 | 杨孝良 | Ointment for treating empyrosis and preparation method thereof |
| CN103893422A (en) * | 2014-04-17 | 2014-07-02 | 江西祥润科技有限公司 | Drug for repairing skin injury and preparation method of drug |
| CN103893422B (en) * | 2014-04-17 | 2018-02-09 | 江西祥润科技有限公司 | Repair medicine of skin injury and preparation method thereof |
| CN104042560A (en) * | 2014-07-08 | 2014-09-17 | 福州绿野生化技术有限公司 | Scar removing liquid containing astragaloside and preparation method of scar removing liquid |
| CN104042560B (en) * | 2014-07-08 | 2016-04-27 | 福州绿野生化技术有限公司 | A kind of scar liquid and preparation method thereof of dispelling containing astragaloside |
| CN105055768A (en) * | 2015-07-07 | 2015-11-18 | 中国人民解放军第四军医大学 | Traditional Chinese medicine compound external-application preparation for treating cicatrix and preparation method and application thereof |
| RU2651057C1 (en) * | 2016-10-26 | 2018-04-18 | Сергей Борисович Богданов | Method of application of vacuum dressing to head |
| RU2655832C2 (en) * | 2016-10-31 | 2018-05-29 | Сергей Борисович Богданов | Method of surgical treatment of patients with total scar facial deformities |
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Open date: 20090429 |