CN101214280B - Chinese medicine for treating burn, scald and sores and preparation thereof - Google Patents
Chinese medicine for treating burn, scald and sores and preparation thereof Download PDFInfo
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- CN101214280B CN101214280B CN2007100564108A CN200710056410A CN101214280B CN 101214280 B CN101214280 B CN 101214280B CN 2007100564108 A CN2007100564108 A CN 2007100564108A CN 200710056410 A CN200710056410 A CN 200710056410A CN 101214280 B CN101214280 B CN 101214280B
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Abstract
The present invention discloses a Chinese medicine for curing burn wounds and surface ulcers. The present invention is made of the following raw materials with the weight portions: 7 to 9 portions of milk veteh, 7 to 9 portions of skullcap root, 3 to 5 portions of forsythia fruit and 3 to 5 portions of lightyellow sophora root. The present invention can be paste and liquid, which has convenient use, no contamination on clothes, no strict requirement on curing environment and less dressing change. The present invention reduces the skin flap grafting operation rate, increases the reversible reactivation probability, produces no desquamation after the skin is recovered, effectively maintains the exudate of wound surface and promotes the growth of wound surface.
Description
Affiliated technical field
The invention belongs to a kind of Chinese medicine composition and preparation method thereof, specifically a kind of Chinese medicine composition for the treatment of burn and wound infections and preparation method thereof.
Background technology
Burn is a kind of common surgery diseases, always adopts " dry heating method ", is exactly the infection at the half-dead tissue of burn wound, scorches or use xeothermic wind with roasting lamp, makes the wound surface drying and dehydrating, impels half-dead tissue necrosis, with the method for control infection.This method cooperates excision slough, the skin grafting of being expert at.The deficiency of its existence is: medical environment conditional request height, must set up aseptic treatment ward and supporting operating room and sick bed; Technical merit to the doctor requires high; The medical expense height; Patient treatment is painful big.Along with the development of medical skill, in the latter stage eighties, China has released MEBT and supporting medicine-moist expose burn ointment, and promotes in the whole nation.This method adopts liquefaction to get rid of slough, utilizes residual skin histology information to come holomorphosis skin.It is not high to medical environment condition and doctor's specification requirement, and the patient suffering is little.But the deficiency of its existence is: easily be infected with medicated clothing, the patient is handicapped, and liquefaction phase dressing change frequency is frequent; The old people of infant and no ability of self control treats relative difficulty.
Summary of the invention
The inventor is through research repeatedly, and by clinical trial, developed the treatment burn and created the external application of Chinese medicine medicine of infections, thereby finished the present invention.
The present invention's purpose, the Chinese medicine composition that is to provide a kind of more effective treatment burn and creates infections.
Another object of the present invention has provided the preparation method of this Chinese medicine composition.
The medicament selection Radix Astragali of the present invention, Radix Scutellariae, Fructus Forsythiae, Radix Sophorae Flavescentis make up, and make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat burn and wound infections.Medicine wherein (1) Radix Astragali: [effect] tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent.[curing mainly] carbuncle card such as do not burst or burst and do not hold back.[test report] Radix Astragali has inhibitory action, immunoregulation effect to bacterial virus, the rat capillary permeability enhancing that can be significantly antihistaminic and 5-hydroxy tryptamine be caused.(2) Radix Scutellariae: [effect] heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis.[curing mainly] carbuncle, furuncle, malignant boil, carbuncle erosion, acute scleritis.[in vitro tests] has inhibitory action to pathogenic bacterium such as bacillus pyocyaneus, staphylococcus, dermatophytess.[animal experiment] has the capillary permeability effect of reduction and removes the free radical effect.(3) Fructus Forsythiae: [effect] heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, diuresis.[curing mainly] affection due to external wind and heat, acute calenture is from the beginning of, dysphoria with smothery sensation coma, and carbuncle sore tumefacting virus waits card.[test report] Fructus Forsythiae has wider antimicrobial spectrum, and staphylococcus aureus, dysentery bacterium, Hemolytic streptococcus, Diplococcus pneumoniae, Bacillus typhi, tubercule bacillus and influenza virus are had inhibitory action; The heart tonifying diuresis is arranged; The vascular permeability of reduction and fragility effect are arranged, prevent the effect of oozing of blood.(4) Radix Sophorae Flavescentis: [effect] heat clearing away, dampness, parasite killing.[curing mainly] skin pruritus, mange, malignant boil, erosion of vulva pruritus due to damp pathogen, scald.[test report] has diuresis and antipathogen effect as tubercule bacillus, dermatophytes and infusorian there being inhibitory action in various degree.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components is for all having better curative effect in the following weight parts scope:
Radix Astragali 7-9 part, Radix Scutellariae 7-9 part, Fructus Forsythiae 3-5 part, Radix Sophorae Flavescentis 3-5 part.
Be preferably: 8 parts of the Radixs Astragali, 8 parts of Radix Scutellariaes, 4 parts of Fructus Forsythiaes, 4 parts of Radix Sophorae Flavescentiss.
Medicine activity component of the present invention is prepared into unguentum and two kinds of dosage forms of liquor, and the two share therapeutic effect better.
Medicine activity component unguentum of the present invention adopts following substrate:
(1) Oleum Sesami: [effect] moistening dryness for relaxing bowels, detoxifcation, granulation promoting.Cards such as [curing mainly] skin ulcer is swollen, ulcer, scabies, chapped skin.
(2) Apis cerana Fabricius: [effect] detoxifcation, removing dampness, hold back skin ulcer, granulation promoting, pain relieving.The inside fire attack of [curing mainly] infections carbuncle, wound infections are burst for a long time and are not held back cards such as burn due to hot liquid or fire.
The substrate that medicine activity component liquor of the present invention adopts is ethanol, ethanol: [effect] promoting blood circulation, resisting cold gas, row medicine gesture.[curing mainly] pain relieving, detumescence.
The preparation method of medicine activity component unguentum of the present invention: with the Radix Astragali, Radix Scutellariae, Fructus Forsythiae, the Radix Sophorae Flavescentis of described weight proportion, go into earth pot, add the Oleum Sesami post-heating, continue 170 hours 40 ℃ of-70 ℃ of temperature, reheat boils to Oleum Sesami is little, plays pot immediately and removes the gred, precipitates, filters, and gets edible vegetable oil on the filtrate, Oleum Sesami, after putting into earth pot, go into Apis cerana Fabricius, the slow fire heating treats that Apis cerana Fabricius promptly stops heating after molten, wait cold, it is standby to stir evenly packaging container.
The preparation method of medicine activity component liquor of the present invention: with the Radix Astragali, Radix Scutellariae, Fructus Forsythiae, the Radix Sophorae Flavescentis of described weight proportion, go into container, add 75% ethanol, under 22 ℃ of-38 ℃ of temperature, airtight sealing up for safekeeping 170 hours, remove the gred then, precipitate, filter, the clear liquid dress hermetic container of getting after the filtration is standby.
Chinese medicine preparation of the present invention can effectively be treated burn (comprising scald, electric burn, chemical burn), wound infections (comprising that chilblain, wound furuncle, decubital ulcer, skin ulcer, soft tissue contusion, traumatic bone expose).The present invention is in clinical practice for many years, and by the treatment to 100 routine all kinds of fire victims, its remarkable efficient is 85%, and total effective rate is 95%.Good effect can effectively reduce the skin flap transplantation operability.
The using method of Chinese medicine preparation of the present invention is as follows.
Method one: behind the wound surface cleaning and sterilizing, coat burn ointment at whole wound surface earlier; Double-deck dressing is soaked into burn liquid, take out to squeeze medicinal liquid to drops physic liquor not and be advisable, cover and scribbling on the wound surface of burn ointment; Outside reuse one deck Dry Dressing wrapping gets final product.Said dressing manufacture method: two-layer absorbent carbasus therebetween one deck absorbent cotton, 6 square metres-8 square metres of general per 500 gram absorbent cotton wool systems.
Method two: double-deck dressing is soaked into burn liquid, take out to squeeze medicinal liquid to drops physic liquor not and be advisable, directly cover on wound surface; Again burn ointment is coated in the dressing.
For the deep burn patient, when using the present invention to treat, wound surface is carried out following processing: with the ploughing and weeding of ploughing and weeding cutter, or with the scalpel line, impelling eliminatings of liquefying as early as possible of burn slough, shortening course of treatment.Changed dressings once in general every 3-7 days.Common burn was changed dressings once in general 5 days, and severe burn was changed dressings once in wound surface liquefaction phase and infection period in 3 days after the large tracts of land; Changed dressings once 7 days convalescent periods.For deep burn, after wound surface does not ooze out, change dressings again once, kept 7 days-12 days, be used to protect wound surface; Dressing is removed in the back, can be coated with the skim burn ointment in the wound surface position, makes not dry and cracked, the desquamation not of wound surface, impels wound surface to continue to increase to thickness.
Chinese medicine preparation burn liquid of the present invention can come the infuse sliver, is used for the treatments such as filling drain of operations such as sinus tract, fistula, abscess otch, is used for vaginitis, the erosion of official's neck outward, and all effect is remarkable.
Four flavor Chinese medicine ingredients of Chinese medicine preparation of the present invention also can be made capsule, are used for the treatment of alimentary canal inflammation, ulcer (comprising esophagitis, gastric and duodenal ulcers, erosive gastritis, superficial gastritis, atrophic gastritis, colitis, proctitis).
Chinese medicine preparation application characteristic of the present invention:
(1) easy to use.The present invention is not infected with medicated clothing, and for the minor burn wound infections patient of middle small size, use is not influence life, study and work.
(2) environmental requirement is low, suits large area to popularize.The present invention is not strict with for the treatment environment, just can use under room temperature environment, therefore can use in any outpatient service.
(3) reduction expense.Changed dressings once in the every 3-7 of Chinese medicine preparation of the present invention days, and reduced dressing change frequency than other treatment scheme, the corresponding workload that reduces medical personnel can be treated use in the low relatively outpatient service of expense for the mild or moderate patient, thereby reduced medical expense.
(4) reduce the skin flap transplantation operability.Clinical showing: Chinese medicine preparation of the present invention, can make the neomorph of skin progenitor cell original position, wound surface for exposed bone, can make periosteum, muscle tendon, subcutaneous fat connective tissue in-situ regenerations such as (granulations), play regeneration site and be from the centre of exposed bone and begin in-situ regeneration, rather than only begin regeneration from the surrounding tissue position of exposed bone, thus the skin flap transplantation operability reduced, even can reduce the generation of amputation.
(5) reversibility that has increased slough is brought back to life probability.Chinese medicine preparation of the present invention when the burn wound of treatment in time, the stem cell below can the downright bad layer of strong activation burn, the centration of the shallow II degree wound surface after the healing is significantly less than other therapies.
(6) desquamation does not take place in the skin after the healing.Chinese medicine preparation of the present invention has activation to burn wound, and for the burn of shallow II degree burn and following degree, after the healing of this preparation, the desquamation phenomenon does not take place skin.
(7) effectively keep wound fluid, promote the growth of wound surface.When using this preparation to treat, owing to form a relatively reasonable space between medicine and the wound surface, can keep the constant not seepage flow of transudate, and the material of contained promotion wound surface growth in the transudate, under this solid environment, more can effectively promote the regeneration of wound surface.
The specific embodiment
Further set forth preparation method of the present invention below by specific embodiment.
The unguentum preparation of [embodiment 1] medicine of the present invention
Get the Radix Astragali 400 grams, Radix Scutellariae 400 grams, Fructus Forsythiae 200 grams, Radix Sophorae Flavescentis 200 grams, go into earth pot, add 5000 gram Oleum Sesami post-heating, continue 170 hours 40 ℃ of-70 ℃ of temperature, reheat boils to Oleum Sesami is little, plays pot immediately and removes the gred, precipitates, filters, and gets edible vegetable oil on the filtrate, Oleum Sesami 5000 grams, after putting into earth pot, go into Apis cerana Fabricius 500 grams-800 grams, the slow fire heating treats that Apis cerana Fabricius promptly stops heating after molten, wait cold, it is standby to stir evenly packaging container.
The liquor preparation of [embodiment 2] medicine of the present invention
Get the Radix Astragali 60 gram, Radix Scutellariae 60 grams, Fructus Forsythiae 30 grams, Radix Sophorae Flavescentis 30 grams, go into container, adds 3 liter of 75% ethanol, under 22 ℃ of-38 ℃ of temperature, airtight sealing up for safekeeping 170 hours removed the gred then, precipitates, filtered, and getting clear liquid after the filtration, to adorn hermetic container standby.
Claims (4)
1. a Chinese medicine for the treatment of burn and wound infections is characterized in that it is made up of following bulk drugs: Radix Astragali 7-9 part, Radix Scutellariae 7-9 part, Fructus Forsythiae 3-5 part and Radix Sophorae Flavescentis 3-5 part.
2. a kind of Chinese medicine for the treatment of burn and wound infections according to claim 1 is characterized in that wherein the preferable amount of each crude drug is: 4 parts of 8 parts of the Radixs Astragali, 8 parts of Radix Scutellariaes, 4 parts of Fructus Forsythiaes and Radix Sophorae Flavescentiss.
3. a kind of unguentum preparation method for the treatment of the Chinese medicine of burn and wound infections according to claim 1 and 2: with the Radix Astragali, Radix Scutellariae, Fructus Forsythiae, the Radix Sophorae Flavescentis of described weight proportion, go into earth pot, add the Oleum Sesami post-heating, continue 170 hours 40 ℃ of-70 ℃ of temperature, reheat boils to Oleum Sesami is little, plays pot immediately and removes the gred, precipitates, filters, and gets edible vegetable oil on the filtrate, Oleum Sesami, after putting into earth pot, go into Apis cerana Fabricius, the slow fire heating treats that Apis cerana Fabricius promptly stops heating after molten, Hou Liang, it is standby to stir evenly packaging container.
4. a kind of liquor preparation method for the treatment of the Chinese medicine of burn and wound infections according to claim 1 and 2: with the Radix Astragali, Radix Scutellariae, Fructus Forsythiae, the Radix Sophorae Flavescentis of described weight proportion, go into container, add 75% ethanol, under 22 ℃ of-38 ℃ of temperature, airtight sealing up for safekeeping 170 hours, remove the gred then, precipitate, filter, the clear liquid dress hermetic container of getting after the filtration is standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100564108A CN101214280B (en) | 2007-01-05 | 2007-01-05 | Chinese medicine for treating burn, scald and sores and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007100564108A CN101214280B (en) | 2007-01-05 | 2007-01-05 | Chinese medicine for treating burn, scald and sores and preparation thereof |
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| Publication Number | Publication Date |
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| CN101214280A CN101214280A (en) | 2008-07-09 |
| CN101214280B true CN101214280B (en) | 2011-01-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2007100564108A Active CN101214280B (en) | 2007-01-05 | 2007-01-05 | Chinese medicine for treating burn, scald and sores and preparation thereof |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105169158A (en) * | 2015-09-18 | 2015-12-23 | 庞群 | External coating ointment for burns and scalds |
| CN112870270B (en) * | 2021-02-26 | 2022-09-20 | 华北理工大学 | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110581A (en) * | 1994-04-21 | 1995-10-25 | 张树森 | External-use decoction with Chinese herbal medicines |
| CN1116539A (en) * | 1995-04-24 | 1996-02-14 | 刘景文 | Burn and scald curing ointment |
| CN1739697A (en) * | 2005-09-02 | 2006-03-01 | 张国梁 | Externally applied ointment for treating burns and scalds |
-
2007
- 2007-01-05 CN CN2007100564108A patent/CN101214280B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110581A (en) * | 1994-04-21 | 1995-10-25 | 张树森 | External-use decoction with Chinese herbal medicines |
| CN1116539A (en) * | 1995-04-24 | 1996-02-14 | 刘景文 | Burn and scald curing ointment |
| CN1739697A (en) * | 2005-09-02 | 2006-03-01 | 张国梁 | Externally applied ointment for treating burns and scalds |
Non-Patent Citations (2)
| Title |
|---|
| 郭静等.外用中医药制剂治疗烧伤的进展.中医外治杂志13 4.2004,13(4),38-39. |
| 郭静等.外用中医药制剂治疗烧伤的进展.中医外治杂志13 4.2004,13(4),38-39. * |
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| CN101214280A (en) | 2008-07-09 |
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