CN106728793A - A kind of porcupine oil medicament for treating empyrosis and skin erosion - Google Patents

A kind of porcupine oil medicament for treating empyrosis and skin erosion Download PDF

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Publication number
CN106728793A
CN106728793A CN201710162527.8A CN201710162527A CN106728793A CN 106728793 A CN106728793 A CN 106728793A CN 201710162527 A CN201710162527 A CN 201710162527A CN 106728793 A CN106728793 A CN 106728793A
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porcupine
parts
oil
medicament
borneol
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刘前军
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Xiangxi Zhangjiajie Porcupine Eco Agriculture Travel Development Co Ltd
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Xiangxi Zhangjiajie Porcupine Eco Agriculture Travel Development Co Ltd
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Publication of CN106728793A publication Critical patent/CN106728793A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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Abstract

The present invention provides a kind of porcupine oil medicament for treating empyrosis and skin erosion, and containing porcupine oil in the medicament, the porcupine oil is the grease extracted from porcupine tissue.Also contain rheum officinale, borneol, cloves, tendril-leaved fritillary bulb in the burn medicament, garden burnet, Asiatic plantain, radix scutellariae, the weight of each component is:100 300 parts of porcupine oil, 68 parts of rheum officinale, 35 parts of borneol, 8 12 parts of cloves, 68 parts of tendril-leaved fritillary bulb, 58 parts of garden burnet, Asiatic plantain 58, radix scutellariae 58.Its preparation method is to crush rheum officinale, borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae respectively, be then sufficiently mixed with porcupine oil.The present invention has the functions such as heat clearing and inflammation relieving, promoting blood circulation and removing blood stasis, dissipating bind dredging collateral, analgesia detumescence, promotion anathrepsis, desalination scar, and for treating upper scald, effective percentage reaches 95.93%.

Description

A kind of porcupine oil medicament for treating empyrosis and skin erosion
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of porcupine oil medicine for treating empyrosis and skin erosion Agent.
Background technology
Burn and scald is generally referred to by including hydrothermal solution, steam, high-temperature gas, flame, electric energy, chemical substance, radioactive ray, scorching hot Histologic lesion caused by the heating power such as metal liquid or solid, is primarily referred to as the infringement of skin or mucous membrane, and severe patient is likely to Other tissues are injured, also to be had be referred to as the thermal damage caused by hydrothermal solution, steam and is scalded, flame, the causer such as electric current is referred to as It is burn.Burn is common clinical, frequently-occurring disease, the pain unbearably caused to patient with it, the easy infection of burn wound and Because infecting a series of physiology, the change of pathology and the serious consequence brought to patient body, Rao Zhe the world of medicine is stranded always.Burn The order of severity depend on wounded tissue scope and depth, depth of burn can be divided into I degree, II degree and III degree.Western medical treatment is slight Burn mainly processes the surface of a wound and prevents local infection;To Large area severe burn, then local treatment and whole body therapeutic are taken simultaneously The principle of weight.Burnt degree focuses on to prevent and treat low CBF shock, and transfusion is given as early as possible to recover blood volume, and gives nutritional support, Correct acid-base balance and Electrolyte imbalance.Reasonable application of antibiotics preventing and treating infection, general first-selection penicillin and the second generation, the 3rd For cynnematin etc., or according to surface of a wound fester Bacteria Culture from enough sensitive antibiotic.To more than Wound treatment using exposure Therapy, topical application antibacterials.III degree of burn is more using the treatment such as skin grafting surgery.The traditional Chinese medical science is controlled using the rule of diagnosis and treatment It.The Chinese herbal medicine formula of existing treatment burn is a lot, " a kind of medicament for treating burn and its preparation as disclosed in Chinese patent Method ", by 19-21 parts of black sanguisorba root, 7-9 parts of ilex pubescens, 14-16 parts of root of large-flowered skullcap, 7-9 parts of coptis, 5-7g parts of rheum officinale, 2-4g parts of Huang Cypress, 5-7g part of two flowers, 9-11g parts of dandelion, 4-6g parts of peppermint borneol, 4-6g parts of Borneolum, 2-4g parts of lactogenesis perfume, 2-4g parts of life do not have Medicine, 2-4g portion of radix cyathulae, 9-11g portions of Chinese gall, 9-11g parts of yellow wax and 200g portions of sesame oil are made, with heat-clearing, ease pain, draw out pus by applying a plaster to the affected part, Anti-inflammatory, promoting blood circulation, dissipating bind dredging collateral, stagnation resolvation, protection skin and mucosa, the function of promotion anathrepsis.But its formula check, without awake scar The effects such as trace.
Porcupine, is Rodentia that a class drapes over one's shoulders spine also known as porcupine.Porcupine is a kind of very high rare dynamic economic worth Thing, with medical value very high.Meat, brain, fat oil, the heart, liver, courage, stomach, arrow thorn can be used as medicine.With step-down, analgesic therapy, work The effects such as blood, stagnation resolvation, wind-dispelling, dredging collateral, cure mainly stomach, hemorrhoid complicated by anal fistula, dislike the illnesss such as sore, cardiovascula arteriosclerosis, leukaemia, rheumatism.Using person of outstanding talent Lard treatment burn has no report.
The content of the invention
It is an object of the invention to provide a kind of porcupine oil medicament for treating empyrosis and skin erosion, it is utilized based on porcupine oil Carrier is wanted, with functions such as heat clearing and inflammation relieving, promoting blood circulation and removing blood stasis, dissipating bind dredging collateral, analgesia detumescence, promotion anathrepsis, is burnt for treating Wound is scalded and skin erosion has good result.
Embodiment of the present invention is:A kind of porcupine oil medicament for treating empyrosis and skin erosion, the burn medicament In containing porcupine oil, the porcupine oil be from porcupine tissue in extract grease.
Further embodiment is:In the burn medicament also contain rheum officinale, borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, Radix scutellariae, the weight of each component is:100-300 parts of porcupine oil, rheum officinale 6-8 parts, borneol 3-5 parts, cloves 8-12 parts, tendril-leaved fritillary bulb 6-8 parts, garden burnet 5-8 parts, Asiatic plantain 5-8, radix scutellariae 5-8.
Further the technical scheme of optimization is that the weight of each component is:200 parts of porcupine oil, 7 parts of rheum officinale, borneol 4 Part, 10 parts of cloves, 7 parts of tendril-leaved fritillary bulb, 6 parts of garden burnet, Asiatic plantain 6, radix scutellariae 6.
The preparation method is that rheum officinale, borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae are crushed respectively, then It is sufficiently mixed with porcupine oil.
In the present invention, the function such as cell tissue that porcupine oil is damaged with anti-inflammatory analgetic, dredging the channel, quick reparation, and a little Desalinate the effect of scar;Rheum officinale, cloves have heat-clearing, removing toxic substances, the effects such as dispelling stasis of blood and stimulating the menstrual flow;Borneol swelling and pain relieving, heat-clearing dissipates poison, dissipate Fire removing toxic substances;Tendril-leaved fritillary bulb can suppress the growth and breeding of the bacteriums such as staphylococcus aureus, there is certain antibacterial action;Garden burnet has cool blood The effects such as hemostasis, clearing heat and detoxicating, the clear yin-nourishing of training, healing up sore and subduing swelling;Asiatic plantain has functions that diuresis, heat-clearing, improving eyesight;The root of large-flowered skullcap can rush down Excess fire, except damp and hot, hemostasis, and with good antibiotic property.Above-mentioned all medicine compatibilities, lead to heat clearing and inflammation relieving, promoting blood circulation and removing blood stasis, dissipating bind The functions such as network, analgesia detumescence, promotion anathrepsis, desalination scar, for treating upper scald, effective percentage reaches 95.93%.
Specific embodiment
Embodiments of the invention are given below and describe the present invention in detail.
Embodiment 1:A kind of porcupine oil medicament for treating empyrosis and skin erosion, is porcupine oil, and the porcupine oil is The grease extracted from porcupine tissue.
Embodiment 2:A kind of porcupine oil medicament for treating empyrosis and skin erosion, is made up of following raw material:Porcupine oil 100g, rheum officinale 8g, borneol 5g parts, cloves 8g, tendril-leaved fritillary bulb 8g, garden burnet 5g, Asiatic plantain 8g, radix scutellariae 5g.Its preparation method be by rheum officinale, Borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae are crushed respectively, be then sufficiently mixed with porcupine oil.
Embodiment 3:A kind of porcupine oil medicament for treating empyrosis and skin erosion, is made up of following raw material:Porcupine oil 300g, rheum officinale 6g, borneol 3g, cloves 12g, tendril-leaved fritillary bulb 8g, garden burnet 5g, Asiatic plantain 8g, radix scutellariae 5g.Its preparation method be by rheum officinale, Borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae are crushed respectively, be then sufficiently mixed with porcupine oil.
Embodiment 4:A kind of porcupine oil medicament for treating empyrosis and skin erosion, is made up of following raw material:Porcupine oil 200g, rheum officinale 7g, borneol 4g, cloves 10g, tendril-leaved fritillary bulb 7g, garden burnet 6g, Asiatic plantain 6g, radix scutellariae 6g.Its preparation method be by rheum officinale, Borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae are crushed respectively, be then sufficiently mixed with porcupine oil.
Embodiment 4 is preferred scheme.
To verify effect of the invention, the present invention has done following clinical observation with regard to embodiment 1 and the spy of embodiment 4:First, case Selection:
Since 2009, using 1 pharmaceutical treatment burned patient of the embodiment of the present invention 32, wherein male 18, women 14, Age 20-56 Sui, all burn surface areas are less than 10% patient, wherein scalding 23, fire wound 9.Use the embodiment of the present invention 4 pharmaceutical treatment burned patients 123.Wherein male 66, women 57, age 12-68 Sui, burn surface area 1%~10% Person 88, more than 10% 35;Boiling water burn 72, fire wound 42, chemical substance is burnt 9.Use two, diagnosis mark It is accurate:According to《Chinese medical disease Standardization of diagnosis and curative effect》, the judgement of depth of burn and percentage using three degree of quarterings, i.e., I degree, II degree (light degree Ⅱ, II degree of depth), III degree of burn.I degree of burn (erythema):Slight red, swollen, hot, pain, hyperesthesia is not got blister, epidermis Dry.II degree of burn (bubble):Light degree Ⅱ:Severe pain, hyperesthesia, temperature increases, and has blister, and substrate is moist, in uniform red, Blister is obvious.It is deep II degree:Hypalgesia, blister is with little or no, throws off epidermis, and substrate drying is pale, there is small blutpunkte, and oedema is bright It is aobvious.III degree of burn (eschar):Anesthesia, inelastic, hard as leather sample, wax are white, sallow or charing is visible subcutaneous after drying Tendon and vessel obstruction such as dendroid.3rd, treatment method:Patient be admitted to hospital after venous transfusion at once, adjust Water-Electrolyte acid-base balance, application Extensive pedigree antibiotic is anti-infective, the simple debridement of burn wound row, the person that has bubble, and bubble is needled, and liquid flows out in making bubble, so SPSS cleaning and sterilizing is used afterwards.After conventional treatment, the surface of a wound is smeared with medicament of the present invention, gauze wrapping, daily dressing 1 It is secondary.Safeguard that viscera function changes simultaneously, to the ill and the treatment such as nutritional support.4th, curative effect judging standard:According to《Chinese medical disease is examined Disconnected criterion of therapeutical effect》Formulate.Cure:Constitutional symptom disappears, wound healing.Take a turn for the better:Constitutional symptom disappears, and the surface of a wound does not heal completely. It is invalid:Constitutional symptom has no improvement, and trauma surface infestation can not be controlled.5th, treatment results:See the table below.
As seen from the above table, with 1 pharmaceutical treatment of the embodiment of the present invention 32, cure 17, take a turn for the better 11, invalid 4, cure Rate 56.25%, efficient 90.63%, inefficiency 9.37%.With 4 pharmaceutical treatment burned patient of the embodiment of the present invention 123, cure 87, take a turn for the better 41, invalid 5, cure rate 70.73%, efficient 95.93%, inefficiency 4.07%.Healing time is 7-17 days, Average 13.1 days.
Model case:Zhang, man, 41 years old, boiling water was scalded, deepⅱdegreeburn, scalding area 5% or so, after conventional treatment, The medicament of the wound surface smearing embodiment of the present invention 2, gauze wrapping, daily dressing 1 time, medication 13 days, constitutional symptom is disappeared, and the surface of a wound is healed Close, cure.

Claims (3)

1. it is a kind of to treat the oily medicament of the porcupine of empyrosis and skin erosion, it is characterised in that to contain porcupine in the burn medicament Oil, the porcupine oil is the grease extracted from porcupine tissue.
2. it is according to claim 1 to treat the oily medicament of the porcupine of empyrosis and skin erosion, it is characterised in that also to contain Rheum officinale, borneol, cloves, tendril-leaved fritillary bulb, garden burnet, Asiatic plantain, radix scutellariae, the weight of each component is:It is 100-300 parts of porcupine oil, big Yellow 6-8 parts, borneol 3-5 parts, cloves 8-12 parts, tendril-leaved fritillary bulb 6-8 parts, garden burnet 5-8 parts, Asiatic plantain 5-8, radix scutellariae 5-8.
It is 3. according to claim 2 to treat the oily medicament of the porcupine of empyrosis and skin erosion, it is characterised in that:Each component Weight be:200 parts of porcupine oil, 7 parts of rheum officinale, 4 parts of borneol, 10 parts of cloves, 7 parts of tendril-leaved fritillary bulb, 6 parts of garden burnet, Asiatic plantain 6, Radix scutellariae 6.
CN201710162527.8A 2017-03-18 2017-03-18 A kind of porcupine oil medicament for treating empyrosis and skin erosion Pending CN106728793A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113694132A (en) * 2021-09-28 2021-11-26 李兴夫 Medicine for treating scald and its preparing method
CN113797300A (en) * 2021-09-16 2021-12-17 李根洪 Formula of porcupine oil for diminishing inflammation, relieving pain and treating burns and scalds and preparation method of porcupine oil

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232723A (en) * 2015-11-02 2016-01-13 郭东玲 Burn moistening ointment
CN106387916A (en) * 2016-09-12 2017-02-15 云南农业大学 Oral microencapsulated porcupine oil and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105232723A (en) * 2015-11-02 2016-01-13 郭东玲 Burn moistening ointment
CN106387916A (en) * 2016-09-12 2017-02-15 云南农业大学 Oral microencapsulated porcupine oil and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
黄倩: "豪猪人工养殖技术", 《农家顾问》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113797300A (en) * 2021-09-16 2021-12-17 李根洪 Formula of porcupine oil for diminishing inflammation, relieving pain and treating burns and scalds and preparation method of porcupine oil
CN113694132A (en) * 2021-09-28 2021-11-26 李兴夫 Medicine for treating scald and its preparing method

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Application publication date: 20170531