CN108578494A - A kind of burn and scald Chinese medicine composition and preparation method thereof - Google Patents
A kind of burn and scald Chinese medicine composition and preparation method thereof Download PDFInfo
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- CN108578494A CN108578494A CN201810578775.5A CN201810578775A CN108578494A CN 108578494 A CN108578494 A CN 108578494A CN 201810578775 A CN201810578775 A CN 201810578775A CN 108578494 A CN108578494 A CN 108578494A
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- burn
- chinese medicine
- scald
- medicine composition
- borneol
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Microbiology (AREA)
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- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine compositions and preparation method thereof for treating burn and scald.The Chinese medicine composition of the present invention is made of garden burnet, radix scutellariae, Asian puccoon, borneol, beeswax, sesame oil etc..The burn and scald Chinese medicine composition of the present invention has significant analgesic effect in the severe pain caused by corresponding burn and scald, can reduce the exudation of burned tissue body fluid, it is anti-infective, remove necrosis and promote granulation, empyrosis wound surface healing it is fast, the advantages that preventing from scar.It is a kind of safe and effective, the burn and scald medicine having no toxic side effect.
Description
Technical field：
The present invention is subordinate to traditional Chinese medicine field.
Background technology：
Burn and scald is incident traumatic disaster in daily life, in the epoch of industrialization high development, is especially changed
The injury of the chemical substance of industrial and commercial bank's industry, occurring area is big, causes group to injure sometimes.So that skin exfoliation, body fluid exudation, pain
It is bitterly hard to bear.If burn and scald area is big, can cause to suffer a shock, threat to life.
Scald degree：
1, I degree is scalded：Only injure epidermis, smartly pain is felt in injured rubefaction, swelling, but anhydrous is bubbled out
It is existing.
2, II degree burn and scald：Skin corium is injured, part is red and swollen, generates heat, in great pain, there is apparent bubble.
Deep II degree：Burn belongs to severe burn, and healing is very slow and leaves sizable scar.The shrunken skin in burn area,
Deformation, influences function.
3, III degree burn and scald：Full thickness skin includes that fat, bone and the muscle below skin all come to harm, and in ash or
Bronzing.
Though the medicament composing prescription for the treatment of burn and scald is traditional Chinese medicine ingredients at present, because of preparation difference, therapeutic effect then has greatly
Difference is dressed if it is using Chinese medicine milling oiling fat, and the effect of relieving the pain plays slow；Since burned tissue liquid oozes out meeting and application
Medicinal powder formed the surface of a wound incrustation；It is unfavorable for the absorption of drug；If the bleeding of empyrosis wound surface will certainly be caused by removing incrustation；No
Conducive to wound healing, it is less useful for the observation of empyrosis wound surface；Chinese medicine easily causes surface of a wound sense without high-temperature sterilization treatment
Dye.
Invention content
The present invention provides a kind of burn and scald Chinese medicine composition, drug use has theoretical foundation, is formulated rigorous, formulation science
Rationally, high temperature formulations are free of any microorganism, easy to use, avoid secondary allotment.
In order to solve the problems in the existing technology, the present invention provides a kind of burn and scald Chinese medicine composition, raw materials
It include the botanical herbs material of following parts by weight：Radix Angelicae Sinensis 40-150, coptis 30-120, rheum officinale 30-110, garden burnet 20-100, radix scutellariae
20-100, Asian puccoon 15-100, borneol 1-30, beeswax 10-50, sesame oil 1500-4000.
Further, the botanical herbs material of following parts by weight is included in raw material：Radix Angelicae Sinensis 60-100, coptis 50-80, rheum officinale
50-100, garden burnet 50-80, radix scutellariae 40-80, Asian puccoon 40-80, borneol 10-20, beeswax 20-30, sesame oil 2000-3000.
Further, the botanical herbs material of following parts by weight is included in raw material：Radix Angelicae Sinensis 100, the coptis 80, rheum officinale 70, garden burnet
60, radix scutellariae 60, Asian puccoon 50, borneol 20, beeswax 30, sesame oil 2500.
The present invention also provides the preparation methods of above-mentioned burn and scald Chinese medicine composition, include the following steps：
(1) sesame oil is added to impregnate 24-48 hours other Chinese medicines in addition to beeswax and borneol.
(2) soaked drug is slowly heated up 20-25 minutes, oil temperature reaches 180~250 DEG C and keeps 10~20, at this time
Drug dark brown is presented, liquid becomes kermesinus, stops heating at this time.
(3) boiled liquid is poured into the container being made ready beforehand for, the container dry disinfection in electric oven, addition
Container is put into fast cooling in cold water by beeswax, borneol.
Further, the dry disinfection temperature in step (3) is 100-200 DEG C, and the time is 10-30 minutes.
Further, the oil temperature in step (2) is up to 200 DEG C, is kept for 10 minutes.
The burn and scald treating oil Chinese medicine composition of the present invention, the pharmacological effect of various bulk pharmaceutical chemicals are respectively：
1. Radix Angelicae Sinensis
Nature and flavor：It is sweet, pungent, warm
Channel tropism：Return liver, the heart, the spleen channel.
Major function
It enriches blood；Promoting blood circulation；It enriches blood；Blood-nourishing, ulcer sores；Injury from falling down
Bibliographic reference：
《Sheng Nong's herbal classic》：All evil wound ulcer gold wounds.
《The formulary of peaceful benevolent dispensary》：Burn sore, it is red to fester, with this myogenic, pull out hot analgesic.
Anti- treating chilblain
Although Chinese medicine think pernio disease performance on the skin, and musculature because capillary spasm necrosis, Radix Angelicae Sinensis support
The benefits of blood is invigorated blood circulation, warming yang for dispelling cold.
Modern pharmacological research：Anti-thrombosis function；Improve blood circulation effect；Effect to smooth flesh；It is anti-inflammatory and
Analgesic activity.
2, the coptis
Medicinal efficacy：
The coptis：Bitter, it is cold in nature, it is nontoxic；Heat-clearing and damp-drying drug, purging intense heat and detonicating, carbuncle swells furunculosis；Control eczema, wet sore outside.
Bibliographic reference：
《Japan hanako materia medica》：It puts on flesh, stop blooding and sore scabies.
《Pharmacological property solution》：Main internal heat is scorching, and mesh disease is broken out, and sore is red and swollen.
Main component：Alkaloid, including based on jamaicin (berberine), coptisine etc..
Modern pharmacological research：
Main component：Alkaloid, including based on jamaicin (berberine), coptisine etc..
Antibacterial action；Antifungic action；Influence to hematological system；Anti-ulcer effect；To platelet aggregation and release
Inhibiting effect.
3, rheum officinale
Nature and flavor：Hardship is trembled with fear.
Channel tropism：Stomach；Large intestine channel；Liver Channel；The spleen channel.
Effect with cure mainly：Traumatic injury；Heat toxin large carbuncle；Erysipelas；Scald；It fries charcoal and is usually used in cooling blood and hemostasis.Purging intense heat and detonicating；It is living
Blood and dissolving stasis；It lets out damp and hot.
Bibliographic reference：
《Japan hanako materia medica》：And apply-cut boil carbuncle poison.
《Compendium of Materia Medica》：Cure mainly all fiery sores.
Modern pharmacological research：
Sequestered Anthraquinones mainly have：Chrysophanol, rheum emodin, Physcion, aloe-emodin, Rhein are to blood
The influence of system.
Hemostasis feature：It acts on definite, quick.
Anastalsis mechanism：Promote adherency and the aggregation capability of blood platelet；Increase platelet count and fibrinogen content；
Reduce Antithrombin III activity；Make the vessel retraction of injured part.
4, garden burnet：
Cold nature, bitter.
Effect with cure mainly：Garden burnet have blood-stanching and blood-cooling, clearing heat and detoxicating, astringing to arrest diarrhea, relieve the pain and inhibit it is a variety of cause a disease micro- lifes
Object acts on.
Modern chemical composition：Reduce the exudation of empyrosis wound surface tissue fluid.
5, radix scutellariae：
Nature and flavor
Taste, it is bitter, it trembles with fear.
Effect with cure mainly：Heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis.
Bibliography：
《Bencao Jingshu》：Bitter cold can remove damp and hot, fiery ulcer person, and internal heat blood trouble, cool blood is except heat, then self-healing.
Modern pharmacological research：Flavonoids compound.
Antibacterial：There is inhibiting effect to a variety of gram positive bacterias, gram-negative bacteria, pathogenic dermatophyte.
It is anti-inflammatory：Inhibit acute inflammatory reaction.Inflammatory seep swelling, capillary permeability is inhibited to increase.
6, Asian puccoon：
Nature and flavor, bitter cold are nontoxic
Bibliography：
《Bencao Jingshu》Burn is treated in promoting blood circulation, cool blood, hemostasis.
Modern pharmacological research：Local administration is hyperfunction to vasopermeability and the inflammation such as edema significantly inhibit, and still increases
Granulation is grown, and promotes wound healing.
7. borneol：
Nature and flavor：Toil, tepor are nontoxic.
Effect with cure mainly：Lead to all keys, dissipates stagnated fire, removes screen improving eyesight, swelling and pain relieving.
Bibliography：
《Medical center bun is wanted》：Borneol master dissipate stagnated fire, can it is deep heat, also can myogenic pain relieving.
Modern study：There is antibacterial, inhibits inflammatory effect.
8. beeswax：
Property it is sweet flat, it is lightly seasoned.
Major function：Removing toxic substances, myogenic, hemostasis, analgesic therapy, ulcer are to hold back.
Bibliography：
《Medical center collection is wanted》：Burn sore, analgesic, poison corruption are controlled into purulence, heat toxin is pulled out with this.
9. sesame oil：
Vitamin E and leukotrienes are rich in sesame oil, wherein vitamin E has antioxidation, can maintain the complete of cell membrane
Whole property and normal function have the function of promoting cell division, softening blood vessel and keep blood vessel elasticity.
If preparing Chinese medicine, there is the effect of clearing heat and detoxicating, cooling blood and relieving pain.
The composition for burn and scald of the present invention uses sesame oil to boil drug for medium, is not available for other burn-scald medicines
's.Traditional Chinese medicine ingredients are complicated, and Chinese medicine preparation compatibility is particular about " monarch minister, helps, makes ".It can just be obtained only in certain medium adequately
Dissolving, drug mutually merge, so that Chinese medicine effect is performed to ultimate attainment, reduce the waste of drug, the composition for burn and scald of preparation makes
With conveniently.
Burn and scald belongs to traumatic sudden illness, is different from " the miscellaneous card of internal injury " and treats.Because drug is epidermal absorption, and
The same prescription is used from beginning to end, this just needs the quantity of drug, and weight, dosage form is more reasonable, takes into account various symptoms comprehensively
Therapeutic effect.
It " relieves the pain in this burn and scald treating oil prescription, reduces tissue exudation, prevents the drugs such as infection, preventing from scar ", compatibility is rigorous,
Where the advantages of medicinal material is cheap and easy to get, reaches optimum therapeuticing effect with minimum medicinal material, this is Chinese medicine treatment disease.
This burn and scald treating oil feature：
1, easy to use, direct to smear, work rapidly.
2, do not have to secondary allotment, save the time.
3, change convenient for tissues observed after smearing the surface of a wound.
4, drug is handled through high-temperature sterilization, other microorganisms is not contained, from superinfection.
5, easy to carry.
The burn and scald Chinese traditional medicine composition application method of the present invention：
Composition for burn and scald is uniformly applied to empyrosis wound surface with swab stick, is continuously smeared after burn and scald treating oil is absorbed
, without wrapping up the surface of a wound.The burn and scald Chinese medicine composition of the present invention has aobvious in the severe pain caused by corresponding burn and scald
The analgesic effect of work, can reduce the exudation of burned tissue body fluid, it is anti-infective, remove necrosis and promote granulation, empyrosis wound surface healing it is fast, do not stay
The advantages that scar.It is a kind of safe and effective, the burn and scald medicine having no toxic side effect.
Description of the drawings
Attached drawing 1 is the pretherapy and post-treatment photos of patient Cao xx for having used the burn and scald Chinese medicine composition of the present invention.
Attached drawing 2 is the pretherapy and post-treatment photos of patient Liu xx for having used the burn and scald Chinese medicine composition of the present invention.
The experimental result (11 for the zoopery that attached drawing 3 is done for the burn and scald Chinese medicine composition of the present invention in University Of Qingdao
The observation of the rat surface of a wound is as shown in Figure 3 after its three kinds of different disposals).
Specific implementation mode
To keep technical scheme of the present invention and advantage clearer, below in conjunction with embodiment to embodiments of the present invention
It is described in further detail.
Embodiment 1：
Following botanical herbs material is taken by weight ratio：Radix Angelicae Sinensis 40, the coptis 30, rheum officinale 30, garden burnet 20, radix scutellariae 20, Asian puccoon 15,
Borneol 1, beeswax 10, sesame oil 1500.
Step：
(1) other Chinese medicines in addition to beeswax and borneol are placed in rustless steel container plus sesame oil impregnates 24 hours.
(2) soaked drug is heated 20 minutes, oil temperature reaches 200 degree and kept for 10 minutes, and drug presentation at this time is black
Brown, liquid become kermesinus, and container internal bulk hair oil is slightly charred taste, stop heating at this time.
(3) boiled liquid is poured into the container being made ready beforehand for, the container is 100 degree, 30 minutes in electric oven
Dry disinfection.Beeswax, borneol are added, container is put into fast cooling in cold water.
Embodiment 2：
Following botanical herbs material is taken by weight ratio：Radix Angelicae Sinensis 150, the coptis 120, rheum officinale 110, garden burnet 100, radix scutellariae 100, purple
Grass 100, borneol 30, beeswax 50, sesame oil 4000.
Step：
(1) other Chinese medicines in addition to beeswax and borneol are placed in rustless steel container plus sesame oil impregnates 48 hours.
(2) soaked drug is heated 25 minutes, oil temperature reaches 250 degree and kept for 15 minutes, and drug presentation at this time is black
Brown, liquid become kermesinus, and container internal bulk hair oil is slightly charred taste, stop heating at this time.
(3) boiled liquid is poured into the container being made ready beforehand for, the container is 100 degree, 30 minutes in electric oven
Dry disinfection.Beeswax, borneol are added, container is put into fast cooling in cold water.
Embodiment 3：
Following botanical herbs material is taken by weight ratio：Radix Angelicae Sinensis 100, the coptis 80, rheum officinale 70, garden burnet 60, radix scutellariae 60, Asian puccoon
50, borneol 20, beeswax 30, sesame oil 2500.
It is prepared according to the method for embodiment 1.
Embodiment 4：
Following botanical herbs material is taken by weight ratio：Radix Angelicae Sinensis 80, the coptis 100, rheum officinale 90, garden burnet 80, radix scutellariae 80, Asian puccoon
70, borneol 10, beeswax 40, sesame oil 3000.
It is prepared according to the method for embodiment 2.
According to clinical verification, Chinese medicine composition made from above-described embodiment is used respectively for 34 burn and scald III degree patients
After 15~20 days, cure rate reaches 100%, remained scar ratio 0.
Typical case：
Cao xx, man, 61 years old, the high willow people in Qingzhou, biped scald, deep II degree, the self-treatment one week of being in, scald wound sense
Dye examines on March 2016 time 23 because suffering from diabetes (10 mMs on an empty stomach of blood glucose).Treatment is passed through：The surface of a wound does debridement treatment,
The burn and scald group and object of the present invention are smeared, incrustation after a week falls off, and does not stay scar.Pretherapy and post-treatment photo is shown in attached drawing 1.
Liu xx, female, 50 years old, Qingzhou Trade City self-operation chemical reagent, to examine 2012 time September 6, by sulfuric acid when work
' chemistry pure ', right foot of burning are treated 15 days outside, are not improved and are carried out my clinic treatment, foot gauze wrapped is scalded when seeing and treating patients, is solved
It is unpleasant to open gauze stink, has suffered dorsal portion skin and largely falls off, scald wound is all covered by purulent core, the visible flesh in deep position
Tendinous tissue.Treatment is passed through：Slough is cleared up, the burn and scald treating oil of the present invention is smeared, with TDP according to the surface of a wound is baked, treats more than 20 days, wound
Face is healed, and does not stay scar.Pretherapy and post-treatment photo is shown in attached drawing 2.
The composition for burn and scald of the present invention, in more than 40 years of Clinical practice, therapeutic domain is wide, such as：Chemicals attack injures, is low
Warm substance frostbite, flame burn, high temperature scald, Early stage bedsore, skin injury and ulcer etc., up to 100%, cure rate reaches effective percentage
100%, remained scar ratio 0.
Contrast experiment
The composition for burn and scald of the present invention is done in October, 2017 in (University Of Qingdao's medical board Qingdao 266071)
《Research of the bright positive burn and scald treating oil to rat deep ii degree burn curative effect》, one group is blank assay group, and two groups of rats use current city
The MEBO ointment for treating scald sold on field, for three groups of rats using Chinese medicine composition of the invention, experimental result is as shown in table 1：
The experimental result for the zoopery that the burn and scald Chinese medicine composition of 1 present invention of table is done in University Of Qingdao
Attached drawing 3 is that the rat surface of a wound is observed after three kinds of different disposals after 11 days.
Experiment conclusion is as follows：This experiment is found, compared to one group and two groups Chinese medicine compositions of blank, Chinese medicine group of the invention
It is slight using rear inflammatory reaction to close object, wound repair is fast, and scarring level is low, therefore can consider that the burn and scald treating oil of the present invention is adding
There is significant curative effect in terms of fast wound repair and reduction cicatrization.It is of the invention and as the traditional treatment means of traditional Chinese medicine
Burn and scald treating oil wet treatment is easy to operate, and effect stability protrudes, and is easily received, new selection is provided for clinical application.This reality
Though it is zoopery to test, the research of its mechanism of action and therapeutic effect can be used as basis and the foundation of clinical application.
Clinical therapeutic efficacy：
Selection comes clinic and treats burned patient totally 120, age 3-70 Sui, wherein 23 people of burn and scald I degree, II degree 68
People, 29 people of III degree.It is randomly divided into two groups, treatment group 60, control group 60.Two groups of cases are through statistical analysis difference without system
Meter learns meaning (P ＞ 0.05), is comparable.
Treatment group is treated using drug prepared by the embodiment of the present invention 3, and the surface of a wound does debridement treatment, smears the present invention's
Drug, daily dressing 2 times, treatment time are 20 days.
Control group uses garden burnet 50g, giant knotweed 30g, Asian puccoon 30g, coptis 20g, radix scutellariae 20g, rheum officinale 20g, bletilla striata 20g, ice
Piece 5g, sesame oil 600ml, beeswax 10g.Usage is identical as treatment group.
Criterion of therapeutical effect, recovery from illness：Wound healing；It is effective：90% or more II degree wound healing, III degree wound healing 50% with
On；Effectively：50% or more II degree wound healing, 30% or more III degree wound healing；In vain：The surface of a wound does not heal.
Statistical result
After 20 days treatment ends, two groups of therapeutic effects are shown in Table 2. drug effective percentage 100% of the present invention, and cure rate 85% is bright
It is aobvious to be better than control group 45%.
The burn and scald Chinese medicine composition and control group drug study Comparative result of 2 present invention of table
| Group | Number | Recovery from illness | It is effective | Effectively | In vain |
| Treatment group | 60 | 51 | 5 | 4 | 0 |
| Control group | 60 | 27 | 11 | 8 | 4 |
Claims (6)
1. a kind of burn and scald Chinese medicine composition is it is characterized in that, its raw material includes the botanical herbs material of following parts by weight：Radix Angelicae Sinensis
40-150, coptis 30-120, rheum officinale 30-110, garden burnet 20-100, radix scutellariae 20-100, Asian puccoon 15-100, borneol 1-30, beeswax
10-50, sesame oil 1500-4000.
2. burn and scald Chinese medicine composition according to claim 1, which is characterized in that include the plant of following parts by weight in raw material
Object Chinese medicine：Radix Angelicae Sinensis 60-100, coptis 50-80, rheum officinale 50-100, garden burnet 50-80, radix scutellariae 40-80, Asian puccoon 40-80, borneol
10-20, beeswax 20-30, sesame oil 2000-3000.
3. burn and scald Chinese medicine composition according to claim 1, which is characterized in that raw material includes the plant of following parts by weight
Object Chinese medicine：Radix Angelicae Sinensis 100, the coptis 80, rheum officinale 70, garden burnet 60, radix scutellariae 60, Asian puccoon 50, borneol 20, beeswax 30, sesame oil 2500.
4. the preparation method of the burn and scald Chinese medicine composition of claim 1-3, it is characterised in that include the following steps：
(1) sesame oil is added to impregnate 24-48 hours other Chinese medicines in addition to beeswax and borneol.
(2) soaked drug is slowly heated up 20-25 minutes, oil temperature reach 180~250 DEG C keep 10~20 minutes, at this time
Drug dark brown is presented, liquid becomes kermesinus, stops heating at this time.
(3) boiled liquid is poured into the container being made ready beforehand for, the container dry disinfection in electric oven adds bee
Container is put into fast cooling in cold water by wax, borneol.
5. the preparation method of burn and scald Chinese medicine composition according to claim 4, which is characterized in that dry in step (3)
Dry sterilisation temp is 100-200 DEG C, and the time is 10-30 minutes.
6. the preparation method of burn and scald Chinese medicine composition according to claim 4, which is characterized in that the oil in step (2)
Up to 200 DEG C of temperature, is kept for 10 minutes.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010462A (en) * | 2018-10-29 | 2018-12-18 | 崔勇全 | Ointment for burns and scalds and preparation method thereof |
| CN110025728A (en) * | 2019-05-23 | 2019-07-19 | 永州市肤速康生物科技有限公司 | A kind of Chinese medicine ointment and its preparation process for treating burn and scald |
| CN110787232A (en) * | 2019-11-22 | 2020-02-14 | 江西佰康药业有限责任公司 | Scald spray and preparation method thereof |
| CN114209752A (en) * | 2022-01-07 | 2022-03-22 | 塔里木大学 | Medicine for treating burn and scald, and preparation method and application thereof |
| CN116270828A (en) * | 2023-05-11 | 2023-06-23 | 济南市中医医院 | Traditional Chinese medicine composition for wound healing and preparation method thereof |
-
2018
- 2018-06-07 CN CN201810578775.5A patent/CN108578494A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010462A (en) * | 2018-10-29 | 2018-12-18 | 崔勇全 | Ointment for burns and scalds and preparation method thereof |
| CN110025728A (en) * | 2019-05-23 | 2019-07-19 | 永州市肤速康生物科技有限公司 | A kind of Chinese medicine ointment and its preparation process for treating burn and scald |
| CN110787232A (en) * | 2019-11-22 | 2020-02-14 | 江西佰康药业有限责任公司 | Scald spray and preparation method thereof |
| CN114209752A (en) * | 2022-01-07 | 2022-03-22 | 塔里木大学 | Medicine for treating burn and scald, and preparation method and application thereof |
| CN116270828A (en) * | 2023-05-11 | 2023-06-23 | 济南市中医医院 | Traditional Chinese medicine composition for wound healing and preparation method thereof |
| CN116270828B (en) * | 2023-05-11 | 2024-01-26 | 济南市中医医院 | Traditional Chinese medicine composition for wound healing and preparation method thereof |
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