CN101721547A - Medicine for treating onychomycosis - Google Patents
Medicine for treating onychomycosis Download PDFInfo
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- CN101721547A CN101721547A CN200810158137A CN200810158137A CN101721547A CN 101721547 A CN101721547 A CN 101721547A CN 200810158137 A CN200810158137 A CN 200810158137A CN 200810158137 A CN200810158137 A CN 200810158137A CN 101721547 A CN101721547 A CN 101721547A
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- tinea unguium
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Abstract
The invention provides a traditional Chinese medicine preparation for treating onychomycosis, which is prepared by raw materials: fineleaf schizonepeta herb, divaricate saposhnikovia root, chaulmoogratree seed, acanthopanax bark, cortex lycii radicis, lightyellow sophora root, Chinese honeylocust fruit, common cnidium fruit and the like. The medicine has the advantages of good treating effect, no toxic and side effect, strong sterilization capability, convenient use for patients, hard recrudescence, etc.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for outer use for the treatment of tinea unguium.
Background technology
Tinea unguium is being commonly called as of infectious disease on a kind of people's of occurring in first, and the traditional Chinese medical science claims " tinea unguium ".Claimed tinea unguium medically, then be tinea unguium now, it is to be caused by the infected by microbes that a big class is called pathogenic fungi.Pathological changes starts from first far-end, lateral margin or first pleat portion, shows as first color and paramophia.Be canescence more, and tarnish; The deck thickens significantly, and the surface is uneven.Tinea unguium influences people's overall appearance, health risk, infringement self-image.Tinea unguium is made troubles to work life, as shakes hands, holds tea, transmits article, visits etc., and he (she) people is reluctant to contact with it.Tinea unguium easily causes various fungal infection, forms serious dermatosis such as tinea manus and pedis, tinea corporis, tinea cruris, erysipelas.Following several mode is taked in the treatment of tinea unguium usually: the one, and first is pulled out in operation.Wound surface is big, and easy infection is easily hemorrhage, and this method wound surface is big, hemorrhage, easily causes infection.Can feel generally after the operation that than pain because " curing the symptoms, not the disease ", general treatment is not ideal, easily infection and recurrence again; Have a heart disease, the patient of hypertension, diabetes etc., treatment should not undergo surgery.The 2nd, endo-medicine.Taking antifungal drug merely has certain curative effect, and convenient.But because this class medicine must reach fungus place, parasitic deck competence exertion antibacterial action, and the dissolubility in water is low waits a moment, it is very fast again to absorb metabolism, so dosage is big, administration time is long.In addition, oral medicine all has side effect, and easily recurrence after the drug withdrawal, so should not be as the conventional therapy medicine of tinea unguium.The 3rd, the external therapy.According to the medicament difference, mainly contain local application and package and cut method such as control.Need cooperate during treatment and remove sick first, thus generally there is not interior oral administration to make things convenient for, but safety, no pain, have no side effect.As whitfield ointment or liniment, miconazole class cream, Liang Jia, daktarin, JIAOXIAN YICIJING etc., but curative effect is lower, easily recurrence, and price is higher.Therefore, the treatment of tinea unguium be it is generally acknowledged there is not specific drug.
Summary of the invention
At above-mentioned weak point, the inventor is through research repeatedly, and by clinical trial, develops that a kind of cost is low, prescription is reasonable, preparation is simple, easy to use, cure rate is high, eutherapeutic medicament.
Purpose of the present invention just provides a kind of medicine for the treatment of tinea unguium, and this curative effect of medication is good, have no side effect, the sterilization ability is strong, the patient is easy to use, more the back is difficult for recurrence.
Choice of drug Herba Schizonepetae of the present invention, Radix Saposhnikoviae, Semen Hydnocarpi core, Cortex Acanthopancis, Cortex Lycii, Radix Sophorae Flavescentis, Fructus Gleditsia, Fructus Cnidii, Alumen are formed.Wherein, the Herba Schizonepetae diffusing wind that induces sweat, rash, the skin ulcer that disappears, hemostasis.The Radix Saposhnikoviae inducing diaphoresis to dispel wind wins and wets, and relieving convulsion is used for rheumatic arthralgia, rubella pruritus etc.Semen Hydnocarpi core dispeiling pathogenic wind and removing dampness, detoxicating and killing parasites.Functions such as Cortex Acanthopancis wind-damp dispelling, strengthening bone and muscle, blood circulation and promoting silt, the diuresis of being good for the stomach.Cortex Lycii has heat clearing away, the effect of removing heat from blood.The Radix Sophorae Flavescentis heat clearing and damp drying, parasite killing, diuresis is used for swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy.Fructus Gleditsia detumescence poison holding, evacuation of pus, parasite killing, external treatment scabies leprosy.Fructus Cnidii dampness is dispeled the wind, parasite killing.Alumen has the detoxifcation parasite killing, dampness removing to stop itchin, hemostasis antidiarrheal, the effect of heat clearing away expectorant.The present invention matches by the Chinese medicine monarch, relends to help edible rice vinegar to have the kill ability very strong to multiple fungus, reaches the purpose of treatment tinea unguium.
The medicine that the present invention treats tinea unguium is to be made by the medicine of following weight parts proportioning: Herba Schizonepetae 30-40 weight portion, Radix Saposhnikoviae 25-30 weight portion, Semen Hydnocarpi core 20-35 weight portion, Cortex Acanthopancis 20-35 weight portion, Cortex Lycii 25-40 weight portion, Radix Sophorae Flavescentis 30-50 weight portion, Fructus Gleditsia 20-30 weight portion, Fructus Cnidii 30-35 weight portion, Alumen 25-50 weight portion.
The specific embodiment
Process for preparing medicine of the present invention is, with the gram is unit of weight, take by weighing each medicine (Herba Schizonepetae 30-40 weight portion promptly takes by weighing Herba Schizonepetae 30-40 gram, and all the other are same) by said ratio, to mix after each medicine pulverizing, add 2000-3000 milliliter edible rice vinegar and soaked about 2 hours, the fiery fried 25-30 of reuse temperature minute, the elimination medicinal residues, to can obtain liquid Chinese medicine preparation after the cooling of gained medicinal liquid, every width of cloth Chinese medicine preparation can use 4 times.
In use, the patient suffer from the hands of tinea unguium or foot put into make Chinese medicine preparation soaked 1 hour, every day, each was once treated 20 days continuously sooner or later, can cure.
It below is clinical observation material of the present invention.
Case is selected, and selects the patient who is diagnosed as tinea unguium according to symptom and examination in hospital to be the object of observation.The liquid Chinese medicine preparation that test group adopts the present invention's medicine to make is treated.Matched group 1 adopts daktarin, matched group 2 to adopt bright first to treat.During treatment, the administrated method of test group for suffer from the hands of tinea unguium or foot put into make Chinese medicine preparation soaked 1 hour, every day, each was once sooner or later.The administrated method of matched group 1 and matched group 2 is according to the description of used product.Test group is totally 100 examples, and matched group 1 is totally 85 examples, and matched group 2 is totally 56 examples.Each organizes the course of disease, degrees of symptoms etc. of case, and comprehensive average back there was no significant difference has comparability between each group.
The criterion of curative effect, 1, cure: bear new fingernail, negative fungal examination.2, effective: tinea unguium partly reduces, negative fungal examination.3, invalid, symptom partly alleviates, the fungus microscope examination positive.
Curative effect situation catalog
| Group | Case load | Cure number | Significant figure | Invalid number | Total effective rate |
| Test group | ??100 | ??85 | ??11 | ??4 | ??96％ |
| Matched group 1 | ??85 | ??26 | ??30 | ??29 | ??65.9％ |
| Matched group 2 | ??56 | ??21 | ??18 | ??17 | ??69.6％ |
As can be seen from the above table, the cure rate of test group is 85%, and the cure rate of matched group 1 is 30.6%, and the cure rate of matched group 2 is 37.5%.The cure rate of test group has been compared the significance effect with two matched groups.The total effective rate of test group is 96%, and the total effective rate of matched group 1 is 65.9%, and the total effective rate of matched group 2 is 69.6%.The effective percentage of test group has been compared with two contrasts the significance effect.
Healing case in the test group is paid a return visit after 1 year and is not all had recurrence.
Average responding time, test group is 3 days, and matched group 1 is 5 days, and matched group 2 is 4.3 days.
In sum, the therapeutic effect of the present invention's medicine obviously is better than two matched groups.
Claims (2)
1. medicine for the treatment of tinea unguium, it is characterized in that it is made by the following weight proportion raw material: Herba Schizonepetae 30-40 weight portion, Radix Saposhnikoviae 25-30 weight portion, Semen Hydnocarpi core 20-35 weight portion, Cortex Acanthopancis 20-35 weight portion, Cortex Lycii 25-40 weight portion, Radix Sophorae Flavescentis 30-50 weight portion, Fructus Gleditsia 20-30 weight portion, Fructus Cnidii 30-35 weight portion, Alumen 25-50 weight portion.
2. a kind of medicine that ash refers to for the treatment of according to claim 1 is characterized in that medicament soaks, boils and form with edible rice vinegar in use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101581374A CN101721547B (en) | 2008-10-24 | 2008-10-24 | Medicine for treating onychomycosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101581374A CN101721547B (en) | 2008-10-24 | 2008-10-24 | Medicine for treating onychomycosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101721547A true CN101721547A (en) | 2010-06-09 |
| CN101721547B CN101721547B (en) | 2012-01-18 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008101581374A Expired - Fee Related CN101721547B (en) | 2008-10-24 | 2008-10-24 | Medicine for treating onychomycosis |
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| Country | Link |
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| CN (1) | CN101721547B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705642A (en) * | 2014-01-14 | 2014-04-09 | 王兴洁 | Traditional Chinese medicine for treating leuconychia |
| CN103989743A (en) * | 2014-05-07 | 2014-08-20 | 张红 | Drug for treating onychomycosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110307C (en) * | 2000-04-24 | 2003-06-04 | 缪振兴 | Medicine for curing tinea unguium |
| CN100356947C (en) * | 2005-08-19 | 2007-12-26 | 吉慧文 | Chinese medicine preparation for treating tinea and its preparation process |
-
2008
- 2008-10-24 CN CN2008101581374A patent/CN101721547B/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705642A (en) * | 2014-01-14 | 2014-04-09 | 王兴洁 | Traditional Chinese medicine for treating leuconychia |
| CN103989743A (en) * | 2014-05-07 | 2014-08-20 | 张红 | Drug for treating onychomycosis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101721547B (en) | 2012-01-18 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120118 Termination date: 20121024 |