CN108066466A - A kind of Chinese medicine composition for treating burn and scald and preparation method and application - Google Patents
A kind of Chinese medicine composition for treating burn and scald and preparation method and application Download PDFInfo
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- CN108066466A CN108066466A CN201810136453.5A CN201810136453A CN108066466A CN 108066466 A CN108066466 A CN 108066466A CN 201810136453 A CN201810136453 A CN 201810136453A CN 108066466 A CN108066466 A CN 108066466A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention discloses a kind of Chinese medicine composition for treating burn and scald, the raw material that the Chinese medicine composition includes following parts by weight is made：15 35 parts of radix aconiti agrestis, 10 30 parts of spinyleaf pricklyash root, 10 25 parts of Asian puccoon, 15 30 parts of Artemisia anomala, 10 25 parts of Radix zanthoxyli.The invention also discloses a kind of preparation method and applications for the Chinese medicine composition for treating burn and scald.The present invention passes through all dialectical compatibilities of taste Chinese medicine, mutually auxiliary help, obtained composition have effects that clearing heat and detoxicating, dampness removing, analgesic hemostatic, activate blood circulation and disperse blood clots, putrefaction-removing granulation-promoting, can rapid healing, and cure after will not hyperplasia incrustation scar, it is raw material that the present invention, which selects natural common Chinese medicinal herbs, and cost is relatively low, and preparation method is simple and easy to operate, obtained Chinese medicine composition is apparent to treatment burn and scald curative effect, and it is nontoxic to human body, it is without any side effects, securely and reliably.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, and in particular to a kind of Chinese medicine composition and its system for treating burn and scald
Preparation Method and application.
Background technology
Burn and scald is a kind of relatively common unexpected injury and a kind of relatively common surgical disease, induces the disease
Because being known as deep fat, fire, steam and boiling water etc., although death will not be caused, it is present with dysfunction and acutely pain
Bitterly, increase psychological pressure and the financial burden of patient, the daily life of patient is caused to seriously affect, so positive symptomatic treatment
It is related to the raising of therapeutic effect to a certain extent.
At present, the drug of burn and scald is treated generally using drug therapy, is mostly Western medicine, of high cost, side effect is big, and past
Toward take effect after use slowly, it is impossible to heal spontaneously as early as possible, serious burn and scald can infect suppurations, even if fully recover after can also stay
Lower scar.
Chinese medicine has rich experience in terms of controlling burn outside, and the theoretical level for controlling burn outside traditional Chinese medicine in recent years is continuously improved,
Clinical experience is enriched constantly, and clinical advantage is more and more apparent.But existing Chinese medicine burn-scald medicine in terms of curative effect there are still
Deficiency, shows as that the wound healing time is long, and effect is general, easy scar.
The content of the invention
The present inventor is cleared away heart-fire using clearing heat and detoxicating, cool blood, clearing damp and promoting diuresis, supplementing qi and nourishing yin is the principles for the treatment of burn and scald, is comformed
It is screened and is compounded in more Chinese medicines, obtained the formula of the present invention.
It is an object of the invention to provide a kind of burn-scald medicines curative for effect, have painless, fast short stopping of adding medicine to
Bitterly, exempt from skin-grafting, healing rate it is fast, more after preventing from scar and it is easy to use, have no toxic side effect, it is safe and reliable the advantages of.
Specifically, to achieve the above object, the first aspect of the present invention provides a kind of Chinese traditional medicine composition for treating burn and scald
Object, the Chinese medicine composition are made of the raw material for including following parts by weight：15-35 parts of radix aconiti agrestis, 10-30 parts of spinyleaf pricklyash root, Asian puccoon
10-25 parts, 15-30 parts of Artemisia anomala, 10-25 parts of Radix zanthoxyli.
Further, the Chinese medicine composition is made of the raw material for including following parts by weight：15-25 parts of radix aconiti agrestis sees blood
16-24 parts winged, 10-20 parts of Asian puccoon, 18-25 parts of Artemisia anomala, 10-20 parts of Radix zanthoxyli.
Further, the Chinese medicine composition is made of the raw material for including following parts by weight：Radix aconiti agrestis 20g, spinyleaf pricklyash root
20g, Asian puccoon 15g, Artemisia anomala 20g, Radix zanthoxyli 15g.
Further, the Chinese medicine composition is external preparation.
The second aspect of the present invention provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment burn and scald, weighs
Each raw material of corresponding parts by weight, is placed in container, adds in white wine, and sealing is impregnated 1 month or more, filter and remove residue, that is, is made and controls
Treat the Chinese medicine composition of burn and scald.
Further, the alcohol concentration of the white wine is more than 95%.The white wine that alcohol concentration is more than 95% can make
The active ingredient of each raw material is fully dissolved out, and ensures the therapeutic effect of Chinese medicine composition, but can effective antiphlogistic and bactericidal, avoid burn and scald
Trauma surface infestation.
Further, the total weight ratio of the white wine and each raw material is 5:1-10:1.
The third aspect of the present invention provides a kind of above-mentioned Chinese medicine composition in the drug for preparing treatment burn and scald
Using.
The application method of Chinese medicine composition of the present invention is：
Chinese medicine composition Direct Uniform is applied to burned patient skin wound, can be applied either with or without exudation, wait to create
Continue to smear after doing in face surface.
Points for attention：The irritation that avoids pungent food and raw food, greasy food.
It is as follows the effect of each taste Chinese medicine selected by the present invention：
Radix aconiti agrestis is the dried root of ranunculaceae plant north rhizome of Chinese monkshood Aconitum kusnezoffii Reichb, and property is hot, taste
Pungent, bitter, the thoughts of returning home, liver,kidney,spleen warp have the effect of dispelling wind and eliminating dampness, antalgic.
Spinyleaf pricklyash root is dicotyledon medicine rutaceae Zanthoxylum dimorphophyllum (Zanthoxylum dimorphophyllum
Hemsl.var.spinifolum Rehd.et Wils.) root or root skin.Warm-natured, acrid flavour, Return liver, lung channel have expelling wind and clearing away cold,
It activates blood and relax tendons, analgesic effect.Modern pharmacological studies have shown that spinyleaf pricklyash root has the effects that hemostasis, blood coagulation.
Asian puccoon is Boraginaceae Lithospermum herbaceos perennial, and cold in nature, sweet in flavor, salty, thoughts of returning home envelope, Liver Channel have
Cool blood, activating blood and clearing heat, removing toxic substances and other effects, tcm clinical practice is mainly used for moist macula, purpura, blood urine, stranguria with turbid discharge and bloody flux, thermojunction
The diseases such as constipation, burn, eczema, erysipelas, large carbuncle.Asian puccoon principle active component has naphthalene Quinone Pigments, phenol, benzoquinones constituents, life
The ingredients such as alkaloids, phenolic acid class, triterpenic acid and acidic polysaccharose, modern pharmacological studies have shown that Asian puccoon has various bacteria apparent inhibition
Effect, and can strengthen local blood circulation, promote epithelial growth, so as to play antibacterial anti-inflammatory, myogenic dispel corruption the effect of.
Artemisia anomala is the herb of feverfew artemisia anomalas, and warm-natured, bitter, the thoughts of returning home, the spleen channel have dispelling wind and eliminating dampness, removing toxic substances life
Flesh, hemostasis and pain-relieving and other effects, among the people, summer people also have direct soaked edible custom, to relieve summer heat, health, health care.
Radix zanthoxyli is Rutaceae Zanthoxylum liana, mild-natured, bitter, pungent, enters liver, stomach,《National Chinese herbal medicine compilation》
It records：" Radix zanthoxyli is invigorated blood circulation, and narcotic analgesic cures mainly neuralgia, taste-blindness rate, stomach and intestine angina, biliary ascariasis and causes
Pain, abscess of throat, and for mucocutaneous anesthesia ".Contain in Radix zanthoxyli there are many active chemical, on tcm clinical practice
Application it is very extensive, rheumatism paralysis, toothache, pain in waist and lower extremities, traumatic injury swelling and pain and the infection such as pharyngitis, lymphnoditis can be treated
Property disease.
The invention has the advantages that：
1st, the present invention is by all dialectical compatibilities of taste Chinese medicine, and mutually auxiliary help, obtained composition has clearing heat and detoxicating, sharp
Wet, analgesic hemostatic, activate blood circulation and disperse blood clots, putrefaction-removing granulation-promoting the effect of, proved through a large amount of clinical tests, can quickly stop wound exudation, dispel
Purulence, healing, without applying other antibiotics, majority of cases can stop oozing out purulence blood for one or two days, and next day starts myogenic, right
In wound inflammation degree than more serious, there is the patient for suppuration of festering, quickly alleviating pain can be played, releived, anti-inflammatory, rapid myogenic, soon
Speed healing, while can split surface of a wound wind resistance, resist drying, achieve the purpose that moisten the maintenance surface of a wound with this, it will not hyperplasia after healing
Incrustation scar.
2nd, it is raw material that the present invention, which selects natural common Chinese medicinal herbs, and cost is relatively low, and preparation method is simple and easy to operate, obtains
Chinese medicine composition to treatment burn and scald curative effect it is apparent and nontoxic to human body, it is without any side effects, securely and reliably.
Specific embodiment
Following embodiment is not limited to the scope of the present invention for illustrating the present invention.
Embodiment 1
A kind of Chinese medicine composition for treating burn and scald, is made of the raw material for including following parts by weight：15 parts of radix aconiti agrestis sees blood
25 parts winged, 15 parts of Asian puccoon, 25 parts of Artemisia anomala, 12 parts of Radix zanthoxyli.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of corresponding parts by weight is weighed, is placed in container, adds in wine
Smart concentration is 95% white wine, and the total weight ratio of white wine and each raw material is 5:1, sealing is impregnated 1 month, filter and remove residue, that is, is made
Treat the Chinese medicine composition of burn and scald.
Embodiment 2
A kind of Chinese medicine composition for treating burn and scald, is made of the raw material for including following parts by weight：35 parts of radix aconiti agrestis sees blood
10 parts winged, 10 parts of Asian puccoon, 20 parts of Artemisia anomala, 20 parts of Radix zanthoxyli.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of corresponding parts by weight is weighed, is placed in container, adds in wine
Smart concentration is 98% white wine, and the total weight ratio of white wine and each raw material is 6:1, sealing is impregnated 45 days, filter and remove residue, that is, is made and is controlled
Treat the Chinese medicine composition of burn and scald.
Embodiment 3
A kind of Chinese medicine composition for treating burn and scald, is made of the raw material for including following parts by weight：15 parts of radix aconiti agrestis sees blood
30 parts winged, 20 parts of Asian puccoon, 30 parts of Artemisia anomala, 10 parts of Radix zanthoxyli.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of corresponding parts by weight is weighed, is placed in container, adds in wine
Smart concentration is 95% white wine, and the total weight ratio of white wine and each raw material is 7:1, sealing is impregnated 2 months, filter and remove residue, that is, is made
Treat the Chinese medicine composition of burn and scald.
Embodiment 4
A kind of Chinese medicine composition for treating burn and scald, the raw material including following parts by weight are made：20 parts of radix aconiti agrestis, spinyleaf pricklyash root
20 parts, 15 parts of Asian puccoon, 20 parts of Artemisia anomala, 15 parts of Radix zanthoxyli.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of corresponding parts by weight is weighed, is placed in container, adds in wine
Smart concentration is 95% white wine, and the total weight ratio of white wine and each raw material is 8:1, sealing is impregnated 1 month, filter and remove residue, that is, is made
Treat the Chinese medicine composition of burn and scald.
Embodiment 5
A kind of Chinese medicine composition for treating burn and scald, is made of the raw material for including following parts by weight：25 parts of radix aconiti agrestis sees blood
16 parts winged, 25 parts of Asian puccoon, 15 parts of Artemisia anomala, 25 parts of Radix zanthoxyli.
The preparation method of above-mentioned Chinese medicine composition is：Each raw material of corresponding parts by weight is weighed, is placed in container, adds in wine
Smart concentration is 98% white wine, and the total weight ratio of white wine and each raw material is 10:1, sealing is impregnated 50 days, filter and remove residue, that is, is made
Treat the Chinese medicine composition of burn and scald.
Test example 1
In order to illustrate Chinese medicine composition of the invention to the therapeutic effect of burn and scald, the present invention has carried out following curative effect examination
It tests.
1st, patient data
My outpatient service in March, 2014 is chosen to 136 burned patients accepted for medical treatment during in March, 2017, is randomly divided into observation
Group and control group, each 68.Women 31 in observation group, male 37, age 2-68 Sui, average age for (35 ± 7.8) year,
Average course of disease be (11 ± 3.6) d, traumatogenic reason：Burn 26, boiling water burn 31, oil scald 11, average burn surface area are
12±8.9cm2；Women 40 in control group, male 28, age 2-70 Sui, average age for (36 ± 4.2) year, average disease
Journey be (10 ± 7.3) d, traumatogenic reason：Burn 23, boiling water burn 36, oil scald 9, average burn surface area for 13 ±
3.4cm2.The general information of two groups of patients is comparable without significant difference (P ＞ 0.05).
2nd, curative effect determinate standard
Recovery from illness：After treatment, simultaneously medicine scab comes off for surface of a wound incrustation healing, and without any infection and pain condition；
Effectively：After treatment, most of wound healing, residual fraction is not cured or wound exudate is reduced, and without infection；
It is invalid：Surface of a wound area is after the treatment without reduction or infection.
3rd, therapy
Observation group：If there is bubble, bubble is first punctured, secretion is squeezed out, after cleaning up wound secretion, by embodiment 4
Chinese medicine composition obtained is directly applied to wounds, continues to smear after surface of a wound surface is done.
Control group：If there is bubble, bubble is first punctured, squeezes out secretion, after cleaning up wound secretion, market is smeared and buys
The dieda wanhua oil come, dieda wanhua oil is embrocated on wounds, and 2-3h is smeared once.
4th, result
Two groups of clinical therapeutic efficacy comparison：By the treatment of 20 days, observation group fully recovered 57, effective 11, and invalid 0
Example treats cure rate 83.8%, total effective rate 100%；Control group is fully recovered 18, effective 34, invalid 16, and treatment always has
Efficiency is 76.5%, the statistically significant (P of comparison among groups<0.05).
Two groups of clinical symptoms extinction time comparison：The secretion of observation group and red and swollen extinction time be respectively (2.1 ±
1.2)、(4.5±1.5)d；And the secretion of control group and red and swollen extinction time are respectively (13.2 ± 2.3), (17.6 ± 2.8)
D, the statistically significant (P of comparison among groups<0.05).
Typical case
Case 1, Feng, female, 6 years old, entire left arm was scalded by the boiling water in vacuum flask, II degree.Bubble first is punctured with pin,
Secretion is squeezed out, after cleaning up wound secretion, then the Chinese medicine composition made from cotton swab Example 4, dab scald position,
Medicine, which is done, to be applied, second day surface of a wound it is red and swollen it is apparent disappear, so smear until the surface of a wound reverts to normal skin, fully recover from an illness repeatedly within the 8th day
More.
Case 2, Lee, man, 39 years old, left and right thigh oil splashed scald, III degree.With alcohol washes are first used, pin punctures bubble, squeezes
Go out secretion, after cleaning up wound secretion, then the Chinese medicine composition made from cotton swab Example 1, dab scald position, medicine
Dry to apply, the 4th day redness is apparent to disappear, and so smears repeatedly until the surface of a wound reverts to normal skin, recovery from illness in the 10th day.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention belong to the scope of protection of present invention.
Claims (8)
1. a kind of Chinese medicine composition for treating burn and scald, which is characterized in that the Chinese medicine composition is by including following parts by weight
Raw material be made：15-35 parts of radix aconiti agrestis, 10-30 parts of spinyleaf pricklyash root, 10-25 parts of Asian puccoon, 15-30 parts of Artemisia anomala, 10-25 parts of Radix zanthoxyli.
2. the Chinese medicine composition of the treatment burn and scald according to power requires 1, which is characterized in that the Chinese medicine composition is by including
The raw material of following parts by weight is made：15-25 parts of radix aconiti agrestis, 16-24 parts of spinyleaf pricklyash root, 10-20 parts of Asian puccoon, 18-25 parts of Artemisia anomala, two
Pin 10-20 parts of face.
3. the Chinese medicine composition of the treatment burn and scald according to power requires 1, which is characterized in that the Chinese medicine composition is by including
The raw material of following parts by weight is made：Radix aconiti agrestis 20g, spinyleaf pricklyash root 20g, Asian puccoon 15g, Artemisia anomala 20g, Radix zanthoxyli 15g.
4. the Chinese medicine composition of the treatment burn and scald according to power requires 1, which is characterized in that the Chinese medicine composition is external application
Preparation.
5. a kind of preparation method for weighing the Chinese medicine composition for requiring the burn and scald of the treatment described in 1, which is characterized in that weigh corresponding weight
Each raw material of number is measured, is placed in container, adds in white wine, sealing is impregnated 1 month or more, filter and remove residue, that is, treatment is made and burns and scalds
The Chinese medicine composition of wound.
6. the preparation method of the Chinese medicine composition for the treatment of burn and scald according to claim 5, which is characterized in that the white wine
Alcohol concentration be more than 95%.
7. the preparation method of the Chinese medicine composition for the treatment of burn and scald according to claim 5, which is characterized in that the white wine
Total weight ratio with each raw material is 5:1-10:1.
8. application of the Chinese medicine composition described in claim 1 in the drug for preparing treatment burn and scald.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111588795A (en) * | 2020-05-22 | 2020-08-28 | 徐勋 | Chinese medicinal composition for treating burn, scald, wound and skin injury, and its preparation method |
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| CN101757180A (en) * | 2008-10-29 | 2010-06-30 | 天津金世制药有限公司 | Traditional Chinese medicine preparation for treating scald and preparation method thereof |
| CN103006867A (en) * | 2012-12-28 | 2013-04-03 | 青岛爱维互动信息技术有限公司 | Miao medicine ointment for treating scalding |
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2018
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| CN101757180A (en) * | 2008-10-29 | 2010-06-30 | 天津金世制药有限公司 | Traditional Chinese medicine preparation for treating scald and preparation method thereof |
| CN103006867A (en) * | 2012-12-28 | 2013-04-03 | 青岛爱维互动信息技术有限公司 | Miao medicine ointment for treating scalding |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111588795A (en) * | 2020-05-22 | 2020-08-28 | 徐勋 | Chinese medicinal composition for treating burn, scald, wound and skin injury, and its preparation method |
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Application publication date: 20180525 |