CN105213870A - A kind of Chinese medicine composition for the treatment of chronic bronchitis - Google Patents
A kind of Chinese medicine composition for the treatment of chronic bronchitis Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for the treatment of chronic bronchitis, it is made up of the raw material of Chinese medicine of following weight: Flos Magnoliae 10, Fructus Xanthii 10, Fructus Citri Sarcodactylis 12, Herba Cirsii 9, the Cortex Eucommiae 5, Radix Scrophulariae 8, Fructus Evodiae 9, coltsfoot 10, Cortex Magnoliae Officinalis 5, the Rhizoma Pinelliae 6, Rhizoma Polygonati 6, Rhizoma Atractylodis 10, Ramulus Cinnamomi 15, Caulis Lonicerae 15, Pheretima 5, Fructus Crataegi 7, Herba Taxilli 10, Fructus Mume 12, Radix Asteris 15, Sargassum 10, Caulis Trachelospermi 12, Caulis Piperis Kadsurae 6, Flos Caryophylli 15, Herba Centipedae 15, Flos Lonicerae 7, Radix Gentianae 7, Fructus Quisqualis 6, Herba Taraxaci 15, Caulis Perillae 15, Herba Houttuyniae 10, Herba speranskiae tuberculatae 15, Herba Lysimachiae 7, Vermilion 6, Herba Ephedrae 7, the Radix Pulsatillae 15, Bulbus Fritillariae Uninbracteatae 12, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8, Fructus Tritici Levis 15.The each raw material of Chinese medicine of the present invention, through dialectical compatibility, plays effect of drying dampness to eliminate phlegm, relieving cough and asthma, lung moistening eliminating stagnation, heat-clearing and toxic substances removing altogether, evident in efficacy to chronic bronchitis patient.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic bronchitis, belong to the field of Chinese medicines.
Background technology
Bronchitis refers to the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue thereof.Bronchitis main cause is that the repeated infection of virus and antibacterial defines bronchial chronic nonspecific inflammation.When under mercury dropped, respiratory tract small blood vessel spasm ischemia, defense function, degradation is beneficial to pathogenic; The chronic stimulations such as smog dust, atmosphere pollution also can be fallen ill; Smoking makes the variation of bronchospasm, mucosa, ciliary movement reduces, mucilage secretion increases advantageous infectivity; Intolerance factors also has certain relation.Except chronic bronchitis refers to chronic cough other a variety of causes after, the annual chronic cough of patient, expectoration more than three months, and continuous 2 years.Might not with the flow limitation of sustainable existence.Primary disease is early stage many without special signs, can hear moist or dry rales a little in the base of lung portion of most of patients.Sometimes can temporary extinction after cough or expectoration.The case of long-term outbreak can find that there is emophysematous sign.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of chronic bronchitis.
The technology used in the present invention solution is:
A kind of Chinese medicine composition for the treatment of chronic bronchitis, it is made up of the raw material of Chinese medicine of following weight: Flos Magnoliae 4-13, Fructus Xanthii 5-11, Fructus Citri Sarcodactylis 9-14, Herba Cirsii 7-18, Cortex Eucommiae 2-15, Radix Scrophulariae 6-13, Fructus Evodiae 7-10, coltsfoot 7-11, Cortex Magnoliae Officinalis 2-17, Rhizoma Pinelliae 5-10, Rhizoma Polygonati 5-10, Rhizoma Atractylodis 5-15, Ramulus Cinnamomi 10-20, Caulis Lonicerae 10-20, Pheretima 3-10, Fructus Crataegi 5-12, Herba Taxilli 6-17, Fructus Mume 5-13, Radix Asteris 6-17, Sargassum 7-14, Caulis Trachelospermi 10-15, Caulis Piperis Kadsurae 5-10, Flos Caryophylli 10-20, Herba Centipedae 10-20, Flos Lonicerae 5-10, Radix Gentianae 5-10, Fructus Quisqualis 5-10, Herba Taraxaci 10-20, Caulis Perillae 10-20, Herba Houttuyniae 5-15, Herba speranskiae tuberculatae 10-20, Herba Lysimachiae 5-10, Vermilion 5-10, Herba Ephedrae 5-10, Radix Pulsatillae 10-20, Bulbus Fritillariae Uninbracteatae 10-20, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10, Fructus Tritici Levis 10-20.
Preferably, the consumption of each raw material of Chinese medicine is: Flos Magnoliae 10, Fructus Xanthii 10, Fructus Citri Sarcodactylis 12, Herba Cirsii 9, the Cortex Eucommiae 5, Radix Scrophulariae 8, Fructus Evodiae 9, coltsfoot 10, Cortex Magnoliae Officinalis 5, the Rhizoma Pinelliae 6, Rhizoma Polygonati 6, Rhizoma Atractylodis 10, Ramulus Cinnamomi 15, Caulis Lonicerae 15, Pheretima 5, Fructus Crataegi 7, Herba Taxilli 10, Fructus Mume 12, Radix Asteris 15, Sargassum 10, Caulis Trachelospermi 12, Caulis Piperis Kadsurae 6, Flos Caryophylli 15, Herba Centipedae 15, Flos Lonicerae 7, Radix Gentianae 7, Fructus Quisqualis 6, Herba Taraxaci 15, Caulis Perillae 15, Herba Houttuyniae 10, Herba speranskiae tuberculatae 15, Herba Lysimachiae 7, Vermilion 6, Herba Ephedrae 7, the Radix Pulsatillae 15, Bulbus Fritillariae Uninbracteatae 12, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8, Fructus Tritici Levis 15.
Above-mentioned Chinese medicine composition can be processed into the multiple dosage forms such as decoction, capsule or tablet according to a conventional method.Wherein, the preparation method of decoction is as follows:
(1) according to above-mentioned weight by Flos Magnoliae, Fructus Xanthii, Fructus Citri Sarcodactylis, Herba Cirsii, the Cortex Eucommiae, Radix Scrophulariae, Fructus Evodiae, coltsfoot, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Rhizoma Polygonati, Rhizoma Atractylodis, Ramulus Cinnamomi, Caulis Lonicerae, Pheretima, Fructus Crataegi, Herba Taxilli, Fructus Mume, Radix Asteris, Sargassum, Caulis Trachelospermi, Caulis Piperis Kadsurae, Flos Caryophylli, Herba Centipedae, Flos Lonicerae, Radix Gentianae, Fructus Quisqualis, Herba Taraxaci, Caulis Perillae, Herba Houttuyniae, Herba speranskiae tuberculatae, Herba Lysimachiae, Vermilion, Herba Ephedrae, the Radix Pulsatillae, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Tritici Levis, mix homogeneously obtains mixture, this mixture is mixed with the ratio of water according to weight ratio 1:8, soak 50 minutes in water.
(2) mixture in described step (1) and soak by water, after 120 minutes, are filtered and obtain the first filtrate and filtering residue.
(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:6, then decoct 100 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.
Pharmacology of the present invention and beneficial effect as follows:
Chronic bronchitis belongs to categories such as Chinese medicine " cough " " asthma " " phlegm retentions ".Its sick origin cause of formation has diseases caused by exogenous pathogenic factor, internal injury two kinds.Diseases caused by exogenous pathogenic factor are many to be violated caused by lung by wind, cold, summer-heat, wet, dry, fiery six climate exopathogens heresy; Patient because lungs are weak or spleen deficiency generating phlegm, flaming up of liver-fire, asthenia of renal qi etc. involve in lung, then belongs to internal injury and causes a disease.The present invention chooses Flos Magnoliae targetedly, Fructus Xanthii, Fructus Citri Sarcodactylis, Herba Cirsii, the Cortex Eucommiae, Radix Scrophulariae, Fructus Evodiae, coltsfoot, Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Rhizoma Polygonati, Rhizoma Atractylodis, Ramulus Cinnamomi, Caulis Lonicerae, Pheretima, Fructus Crataegi, Herba Taxilli, Fructus Mume, Radix Asteris, Sargassum, Caulis Trachelospermi, Caulis Piperis Kadsurae, Flos Caryophylli, Herba Centipedae, Flos Lonicerae, Radix Gentianae, Fructus Quisqualis, Herba Taraxaci, Caulis Perillae, Herba Houttuyniae, Herba speranskiae tuberculatae, Herba Lysimachiae, Vermilion, Herba Ephedrae, the Radix Pulsatillae, Bulbus Fritillariae Uninbracteatae, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Tritici Levis is totally 38 taste raw material of Chinese medicine.
Wherein: Flos Magnoliae, dispersing wind and cold, clearing the nasal passage.
Fructus Xanthii, loose wind dehumidifying, understand things pain-stopping.
Fructus Citri Sarcodactylis, liver-smoothing, qi-regulating, and stomach and alleviating pain.
Herba Cirsii, cooling blood for hemostasis, promoting blood circulation and detoxication.
The Cortex Eucommiae, tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.
Radix Scrophulariae, clearing away heat and cooling blood, removing toxic substances, eliminating stagnation sore-throat relieving, YIN nourishing.
Fructus Evodiae, dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.
Coltsfoot, nourishing the lung to keep the adverse QI downward, reduce phlegm antitussive.
Cortex Magnoliae Officinalis, circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.
The Rhizoma Pinelliae, has drying dampness to eliminate phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI.
Rhizoma Polygonati, boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.
Rhizoma Atractylodis, drying damp and strengthening spleen, expelling wind and cold.
Ramulus Cinnamomi, diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.
Caulis Lonicerae, has heat-clearing and toxic substances removing, the curative effect of dispelling wind dredging collateral.
Pheretima, has heat clearing away arresting convulsion, effect that dysmenorrhea is active.
Fructus Crataegi, has the effects such as blood fat reducing, blood pressure, heart tonifying, arrhythmia.
Herba Taxilli, invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.Radix Achyranthis Bidentatae, Herba Taxilli and Os Draconis use, strengthen effect of nourishing the liver and kidney.
Fructus Mume, astringes the lung, and astringing intestine to stop diarrhea promotes the production of body fluid, relieving colic caused by ascaris.
Radix Asteris, nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.
Sargassum, heat clearing away, hard masses softening and resolving, softening the hard mass, expectorant, diuretic detumescent.
Caulis Trachelospermi, dispelling wind and removing obstruction in the collateral, removing heat from blood are subsided a swelling.
Caulis Piperis Kadsurae, wind-damp dispelling, the meridian dredging.
Flos Caryophylli, warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.
The effects such as Herba Centipedae, has dispersing wind-cold, clearing the nasal passage, cough-relieving, removing toxic substances, antipruritic.
Flos Lonicerae, heat-clearing and toxic substances removing.
Radix Gentianae, heat clearing and damp drying, eliminating pathogen in the liver is calmed the frightened.
Fructus Quisqualis, removing food stagnancy, spleen invigorating, parasite killing relieving constipation.
Herba Taraxaci, has the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.
Caulis Perillae, circulation of qi promoting and in.
Herba Houttuyniae, heat-clearing and toxic substances removing, detumescence treat skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, invigorating the stomach and promoting digestion.
Herba speranskiae tuberculatae, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, solution poison rash.
Herba Lysimachiae, relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, eliminating damp-heat.
Vermilion, eliminates the phlegm, and broken knot, parasite killing, controls skin ulcer.
Herba Ephedrae, diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.
The Radix Pulsatillae, has heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites.
Bulbus Fritillariae Uninbracteatae, lung moistening eliminating stagnation, antitussive reduces phlegm.
The Pseudobulbus Bletillae (Rhizoma Bletillae), tonifying the lung, hemostasis, detumescence, granulation promoting, sore.
Fructus Tritici Levis, except deficiency-heat; Hidroschesis.
Full side's compatibility, plays effect of drying dampness to eliminate phlegm, relieving cough and asthma, lung moistening eliminating stagnation, heat-clearing and toxic substances removing altogether, evident in efficacy to chronic bronchitis patient.
Clinical data
For showing the therapeutic effect of medicine of the present invention, the present invention carries out the clinical research of system to 120 routine chronic bronchitis patients.
Treatment group: choose 60 examples by random method, on former treatment basis, all medicines of stopping using, take Drug therapy of the present invention 1 month.
Matched group: choose 60 examples by random method, utilize traditional Western medicine cephalosporin, TANKEJING treats 1 month.
Two groups in the state of an illness, sex, age, the course of disease etc. through statistical procedures no significant difference.
Instructions of taking: treatment group: the decoction 200 milliliters sooner or later respectively once taking medicine of the present invention every day, the course for the treatment of is 1 month.Matched group: give cephalosporin 0.5g (2), TANKEJING 1g (2), every day 3 times, buccal after the meal, the course for the treatment of is 1 month.
Observation index and method
With reference to the standard of " new Chinese medicine guideline of clinical investigations ".
Treatment group, cures 54 examples, effective 6 examples, invalid 0 example, total effective rate 100%.Matched group, cures 26 examples, effective 20 examples, invalid 14 examples, total effective rate 76.67%.Between two groups, difference has very significant, and treatment group is obviously better than matched group.
Detailed description of the invention
Embodiment 1
Each raw material of Chinese medicine is taken by following weight:
Flos Magnoliae 10, Fructus Xanthii 10, Fructus Citri Sarcodactylis 12, Herba Cirsii 9, the Cortex Eucommiae 5, Radix Scrophulariae 8, Fructus Evodiae 9, coltsfoot 10, Cortex Magnoliae Officinalis 5, the Rhizoma Pinelliae 6, Rhizoma Polygonati 6, Rhizoma Atractylodis 10, Ramulus Cinnamomi 15, Caulis Lonicerae 15, Pheretima 5, Fructus Crataegi 7, Herba Taxilli 10, Fructus Mume 12, Radix Asteris 15, Sargassum 10, Caulis Trachelospermi 12, Caulis Piperis Kadsurae 6, Flos Caryophylli 15, Herba Centipedae 15, Flos Lonicerae 7, Radix Gentianae 7, Fructus Quisqualis 6, Herba Taraxaci 15, Caulis Perillae 15, Herba Houttuyniae 10, Herba speranskiae tuberculatae 15, Herba Lysimachiae 7, Vermilion 6, Herba Ephedrae 7, the Radix Pulsatillae 15, Bulbus Fritillariae Uninbracteatae 12, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8, Fructus Tritici Levis 15.
Preparation method is as follows:
(1) by above-mentioned each raw material of Chinese medicine mix homogeneously, obtain mixture, this mixture is mixed with the ratio of water according to weight ratio 1:8, soak 50 minutes in water.
(2) mixture in described step (1) and soak by water, after 120 minutes, are filtered and obtain the first filtrate and filtering residue.
(3) gained filtering residue in described step (2) is mixed with the ratio of water according to weight ratio 1:6, then decoct 100 minutes, then filter and obtain the second filtrate and filtering residue, the first filtrate is mixed with the second filtrate, obtain the decoction of medicine.
Embodiment 2
Each raw material of Chinese medicine is taken by following weight:
Flos Magnoliae 4, Fructus Xanthii 11, Fructus Citri Sarcodactylis 14, Herba Cirsii 7, the Cortex Eucommiae 2, Radix Scrophulariae 13, Fructus Evodiae 7, coltsfoot 11, Cortex Magnoliae Officinalis 2, the Rhizoma Pinelliae 5, Rhizoma Polygonati 5, Rhizoma Atractylodis 15, Ramulus Cinnamomi 20, Caulis Lonicerae 10, Pheretima 3, Fructus Crataegi 12, Herba Taxilli 6, Fructus Mume 5, Radix Asteris 17, Sargassum 14, Caulis Trachelospermi 10, Caulis Piperis Kadsurae 5, Flos Caryophylli 20, Herba Centipedae 20, Flos Lonicerae 5, Radix Gentianae 5, Fructus Quisqualis 10, Herba Taraxaci 10, Caulis Perillae 20, Herba Houttuyniae 15, Herba speranskiae tuberculatae 20, Herba Lysimachiae 10, Vermilion 5, Herba Ephedrae 5, the Radix Pulsatillae 20, Bulbus Fritillariae Uninbracteatae 10, the Pseudobulbus Bletillae (Rhizoma Bletillae) 5, Fructus Tritici Levis 20.
Preparation method is with embodiment 1.
Embodiment 3
Each raw material of Chinese medicine is taken by following weight:
Flos Magnoliae 13, Fructus Xanthii 5, Fructus Citri Sarcodactylis 9, Herba Cirsii 18, the Cortex Eucommiae 15, Radix Scrophulariae 6, Fructus Evodiae 10, coltsfoot 7, Cortex Magnoliae Officinalis 17, the Rhizoma Pinelliae 10, Rhizoma Polygonati 10, Rhizoma Atractylodis 5, Ramulus Cinnamomi 10, Caulis Lonicerae 20, Pheretima 10, Fructus Crataegi 5, Herba Taxilli 17, Fructus Mume 13, Radix Asteris 6, Sargassum 7, Caulis Trachelospermi 15, Caulis Piperis Kadsurae 10, Flos Caryophylli 10, Herba Centipedae 10, Flos Lonicerae 10, Radix Gentianae 10, Fructus Quisqualis 5, Herba Taraxaci 20, Caulis Perillae 10, Herba Houttuyniae 5, Herba speranskiae tuberculatae 10, Herba Lysimachiae 5, Vermilion 10, Herba Ephedrae 10, the Radix Pulsatillae 10, Bulbus Fritillariae Uninbracteatae 20, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Fructus Tritici Levis 10.
Make granule according to a conventional method.
Claims (2)
1. treat the Chinese medicine composition of chronic bronchitis for one kind, it is characterized in that it is made up of the raw material of Chinese medicine of following weight: Flos Magnoliae 4-13, Fructus Xanthii 5-11, Fructus Citri Sarcodactylis 9-14, Herba Cirsii 7-18, Cortex Eucommiae 2-15, Radix Scrophulariae 6-13, Fructus Evodiae 7-10, coltsfoot 7-11, Cortex Magnoliae Officinalis 2-17, Rhizoma Pinelliae 5-10, Rhizoma Polygonati 5-10, Rhizoma Atractylodis 5-15, Ramulus Cinnamomi 10-20, Caulis Lonicerae 10-20, Pheretima 3-10, Fructus Crataegi 5-12, Herba Taxilli 6-17, Fructus Mume 5-13, Radix Asteris 6-17, Sargassum 7-14, Caulis Trachelospermi 10-15, Caulis Piperis Kadsurae 5-10, Flos Caryophylli 10-20, Herba Centipedae 10-20, Flos Lonicerae 5-10, Radix Gentianae 5-10, Fructus Quisqualis 5-10, Herba Taraxaci 10-20, Caulis Perillae 10-20, Herba Houttuyniae 5-15, Herba speranskiae tuberculatae 10-20, Herba Lysimachiae 5-10, Vermilion 5-10, Herba Ephedrae 5-10, Radix Pulsatillae 10-20, Bulbus Fritillariae Uninbracteatae 10-20, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-10, Fructus Tritici Levis 10-20.
2. a kind of Chinese medicine composition for the treatment of chronic bronchitis according to claim 1, it is characterized in that the consumption of each raw material of Chinese medicine is: Flos Magnoliae 10, Fructus Xanthii 10, Fructus Citri Sarcodactylis 12, Herba Cirsii 9, the Cortex Eucommiae 5, Radix Scrophulariae 8, Fructus Evodiae 9, coltsfoot 10, Cortex Magnoliae Officinalis 5, the Rhizoma Pinelliae 6, Rhizoma Polygonati 6, Rhizoma Atractylodis 10, Ramulus Cinnamomi 15, Caulis Lonicerae 15, Pheretima 5, Fructus Crataegi 7, Herba Taxilli 10, Fructus Mume 12, Radix Asteris 15, Sargassum 10, Caulis Trachelospermi 12, Caulis Piperis Kadsurae 6, Flos Caryophylli 15, Herba Centipedae 15, Flos Lonicerae 7, Radix Gentianae 7, Fructus Quisqualis 6, Herba Taraxaci 15, Caulis Perillae 15, Herba Houttuyniae 10, Herba speranskiae tuberculatae 15, Herba Lysimachiae 7, Vermilion 6, Herba Ephedrae 7, the Radix Pulsatillae 15, Bulbus Fritillariae Uninbracteatae 12, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8, Fructus Tritici Levis 15.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497652A (en) * | 2016-01-28 | 2016-04-20 | 高桂田 | Traditional Chinese medicine for treating bronchitis |
| CN105641510A (en) * | 2016-01-14 | 2016-06-08 | 青岛大学附属医院 | Traditional Chinese medicine composition for treating child obliterans bronchiolitis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103690898A (en) * | 2013-12-27 | 2014-04-02 | 魏本松 | Traditional Chinese medicine for treating bronchitis |
| CN103877518A (en) * | 2014-04-11 | 2014-06-25 | 王家玲 | Traditional Chinese medicine for treating bronchitis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103690898A (en) * | 2013-12-27 | 2014-04-02 | 魏本松 | Traditional Chinese medicine for treating bronchitis |
| CN103877518A (en) * | 2014-04-11 | 2014-06-25 | 王家玲 | Traditional Chinese medicine for treating bronchitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105641510A (en) * | 2016-01-14 | 2016-06-08 | 青岛大学附属医院 | Traditional Chinese medicine composition for treating child obliterans bronchiolitis |
| CN105497652A (en) * | 2016-01-28 | 2016-04-20 | 高桂田 | Traditional Chinese medicine for treating bronchitis |
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