CN112336657A - Cleaning and disinfecting hand sanitizer and preparation method thereof - Google Patents
Cleaning and disinfecting hand sanitizer and preparation method thereof Download PDFInfo
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- CN112336657A CN112336657A CN201910721561.3A CN201910721561A CN112336657A CN 112336657 A CN112336657 A CN 112336657A CN 201910721561 A CN201910721561 A CN 201910721561A CN 112336657 A CN112336657 A CN 112336657A
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- hand sanitizer
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- chitin
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- 238000002360 preparation method Methods 0.000 title claims description 9
- 230000000249 desinfective effect Effects 0.000 title description 8
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 63
- 239000000284 extract Substances 0.000 claims abstract description 36
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- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 23
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- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 description 1
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- XUSYGBPHQBWGAD-PJSUUKDQSA-N Carnosol Chemical compound CC([C@@H]1C2)(C)CCC[C@@]11C(=O)O[C@@H]2C2=C1C(O)=C(O)C(C(C)C)=C2 XUSYGBPHQBWGAD-PJSUUKDQSA-N 0.000 description 1
- MMFRMKXYTWBMOM-UHFFFAOYSA-N Carnosol Natural products CCc1cc2C3CC4C(C)(C)CCCC4(C(=O)O3)c2c(O)c1O MMFRMKXYTWBMOM-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Abstract
A hand sanitizer for cleaning and disinfection is prepared from the following raw materials in parts by weight: 25.0 to 30.0 parts of Quillaja bark extract, 0.25 to 0.5 part of tea catechins, 0.5 to 1.0 part of lecithin, 2.0 to 5.0 parts of rosemary extract, 1.0 to 2.0 parts of ginkgo leaf extract, 3.0 to 5.0 parts of chitin, 2.0 to 3.0 parts of decyl glucoside, 0.5 to 1.0 part of Chondrus crispus extract, 3.0 to 5.0 parts of sodium surfactin, 0.2 to 0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05 to 0.2 part of citric acid and 62.5 to 46.8 parts of water. The hand sanitizer is a multiple natural plant extract, is prepared from natural raw materials, and has high safety to skin and hair of people. Accomplish when clean, also have very big effect in the aspect of the disinfection, compare with the liquid soap on the market, add washing product with the raw materials that natural plant extraction and refining obtained, solved the injury of chemical composition to human skin when accomplishing basic effect, greatly reduced irritability, really reach the purpose of two unifications, have clean and sterile synergism.
Description
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a hand sanitizer with cleaning and disinfecting effects and a preparation method thereof.
Background
The current society develops rapidly, the requirements of people on washing products are increased day by day, and the development gradually evolves from the earliest purpose of single cleaning to the 21 st century with complex and diversified product requirements. The product is safer, has low irritation and has synergistic effect, thus being the pursuit of the vast consumers. The hand sanitizer is an essential washing liquid which has the main functions of hand cleaning and has the functions of disinfection, sterilization and the like, and plays an indispensable role in the life of people. The basic criteria for assessing a hand cleanser should be: firstly, the cleaning ability is required to remove stains and bacteria; secondly, important indexes of the foam stabilizer are the foaming capacity and the lasting foam stabilizing capacity of the components, and the easy flushing is also the basis for bringing the burden-free experience to the user; thirdly, the hand sanitizer is required to have excellent sterilization capability because of being used in public places. Meanwhile, chemical components in part of commercially available hand sanitizer are easy to irritate part of people, cause allergy and cause skin injury. The hand sanitizer of the invention replaces chemical components with more natural components, really achieves the integration of cleaning and disinfection in action, and is mild, safe and low in stimulation.
Disclosure of Invention
The invention aims to provide the hand sanitizer prepared from the raw materials extracted naturally, which has no stimulation to skin and has cleaning and disinfecting effects.
The invention provides a hand sanitizer for cleaning and disinfection, which is prepared from the following raw materials in parts by weight: 25.0 to 30.0 parts of Quillaja bark extract, 0.25 to 0.5 part of tea catechins, 0.5 to 1.0 part of lecithin, 2.0 to 5.0 parts of rosemary extract, 1.0 to 2.0 parts of ginkgo leaf extract, 3.0 to 5.0 parts of chitin, 2.0 to 3.0 parts of decyl glucoside, 0.5 to 1.0 part of Chondrus crispus extract, 3.0 to 5.0 parts of sodium surfactin, 0.2 to 0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05 to 0.2 part of citric acid and 62.5 to 46.8 parts of water.
Preferably, the hand sanitizer for cleaning and disinfection is prepared from the following raw materials in parts by weight: 25.0-28.0 parts of quillaja bark extract, 0.25-0.4 part of tea catechins, 0.7-1.0 part of lecithin, 2.5-4.0 parts of rosemary extract, 1.0-1.5 parts of ginkgo leaf extract, 3.0-4.0 parts of chitin, 2.5-3.0 parts of decyl glucoside, 0.6-0.95 part of carrageen crispus extract, 4.0-5.0 parts of sodium surfactin, 0.25-0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05-0.2 part of citric acid and 60.15-51.45 parts of water.
The invention also provides a preparation method of the hand sanitizer for cleaning and disinfection, which comprises the following steps:
(1) adding water, Quillaja bark extract, chitin, Chondrus crispus extract and hydrolyzed sclerotium rolfsii gum into the sterilized reaction kettle according to the proportion, heating and dissolving at the temperature of 70-80 ℃, the stirring speed of 150-200 RPM and the stirring time of 20-30 min to form a mixed solution;
(2) continuously keeping the temperature of the mixed solution at 70-80 ℃, stirring at the speed of 150-200 RPM, then adding citric acid and decyl glucoside, stirring at the speed of 150-200 RPM, and keeping the temperature for 5 min;
(3) and (3) after the mixed solution is stirred and cooled to 35-40 ℃, the stirring speed is 200RPM, and the other components, namely tea catechins, lecithin, rosemary extract, ginkgo leaf extract and sodium surfactin are added, wherein the stirring speed is 150-200 RPM, and the temperature is 20-25 ℃.
The invention has the beneficial effects that: the hand sanitizer is a multiple natural plant extract, is prepared from natural raw materials, and has high safety to skin and hair of people. Accomplish when clean, also have very big effect in the aspect of the disinfection, compare with the liquid soap on the market, add washing product with the raw materials that natural plant extraction and refining obtained, solved the injury of chemical composition to human skin when accomplishing basic effect, greatly reduced irritability, really reach the purpose of two unifications, have clean and sterile synergism.
Detailed Description
The invention provides a cleaning and disinfecting hand sanitizer, which adopts a natural extracted plant extract as a main component and is prepared by mixing the following components: quillaja bark extract, tea catechins, lecithin, rosemary extract, ginkgo biloba extract, chitin, decyl glucoside, Chondrus crispus extract, sodium surfactin, hydrolyzed sclerotium gum, citric acid and water.
The effects of the ingredients in the hand sanitizer are described below.
Quillaja saponaria extract is taken from bark of Quillaja saponaria, and contains triterpenoid saponin with excellent foaming performance, aglycone with different degrees of lipophilicity and carbohydrate chain with strong hydrophilicity, so that saponin becomes a surfactant, and after being shaken in an aqueous solution, the extract can generate lasting soap-like foam, can be used as a mild natural surfactant for more purposes, and can also prevent mildew. The plant extract rich in saponin can be used for preparing emulsifier, detergent, foaming agent, etc.
Tea catechins, catechin is an extracted phenol, is derived from natural plants such as tea leaves, and has excellent oxidation resistance, tumor resistance, germ resistance and the like.
Lecithin, also known as lecithin, together with proteins and vitamins is called "third dimension", supplements the body's needs in the diet, regulates serum lipids, improves fat absorption, and positively affects heart health and brain development. The lecithin has good hydrophilic and lipophilic power, and can improve appearance, make skin glossy, and improve cell regeneration ability.
Rosemary extracts, also called olea europaea, containing three components, namely rosmanol, carnosol and carnosic acid, are excellent high-efficiency natural antioxidant components, contain diterpenes, flavonoids and triterpenes, and are formulated in the field of aging delaying.
The ginkgo leaf extract is light yellow flowable powder extracted from dry ginkgo leaves, and the ginkgo leaves are widely cited by heart, cerebral vessels and nervous systems in Chinese medicine, and have the functions of inflammation resistance, allergy resistance and oxidation resistance in pharmaceutical research; the sodium surfactin is the sodium salt of the surfactin, has a unique cyclic peptide structure, and is widely applied to the field of daily chemicals as a natural surfactant.
Chitin, also called chitin, is derived from animal and plant shells in the nature, is the sixth element of human health and storage, is purely natural, safe, non-toxic and free of side effects, and can activate immunity, improve physique pH, sterilize and diminish inflammation.
Decyl glucoside, as nonionic surfactant, it has low surface tension, the detergency is good, the dissolubility is good, high temperature resistant, alkali-resistant and high-concentration electrolyte-resistant, there is good thickening effect, the compatibility is good, can produce the synergistic effect with various ionic type, nonionic surfactant complex, and can improve the mildness of the formulation apparently; good foamability, rich, fine and stable foam, good compatibility with skin, no toxicity, no irritation, and rapid and complete biodegradation.
Chondrus crispus extract is derived from natural seaweed, and has effects of improving skin protection ability by adsorbing cation aging substances of skin with a large amount of anions, keeping moisture, inhibiting leukocyte elastase, relieving inflammation and allergy, and thickening in water solution.
Hydrolyzed scleroglucan, also known as scleroglucan, is a natural polymer of polysaccharides. The polysaccharide polymer is stable at high temperature and various pH values, is a polysaccharide polymer, has good compatibility with skin, can effectively form a film, is stable, and can preserve moisture, thicken and resist inflammation.
The invention provides a hand sanitizer for cleaning and disinfection, which is prepared from the following raw materials in parts by weight: 25.0 to 30.0 parts of Quillaja bark extract, 0.25 to 0.5 part of tea catechins, 0.5 to 1.0 part of lecithin, 2.0 to 5.0 parts of rosemary extract, 1.0 to 2.0 parts of ginkgo leaf extract, 3.0 to 5.0 parts of chitin, 2.0 to 3.0 parts of decyl glucoside, 0.5 to 1.0 part of Chondrus crispus extract, 3.0 to 5.0 parts of sodium surfactin, 0.2 to 0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05 to 0.2 part of citric acid and 62.5 to 46.8 parts of water.
Preferably, the hand sanitizer for cleaning and disinfection is prepared from the following raw materials in parts by weight: 25.0-28.0 parts of quillaja bark extract, 0.25-0.4 part of tea catechins, 0.7-1.0 part of lecithin, 2.5-4.0 parts of rosemary extract, 1.0-1.5 parts of ginkgo leaf extract, 3.0-4.0 parts of chitin, 2.5-3.0 parts of decyl glucoside, 0.6-0.95 part of carrageen crispus extract, 4.0-5.0 parts of sodium surfactin, 0.25-0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05-0.2 part of citric acid and 60.15-51.45 parts of water.
Example one
The embodiment provides a hand sanitizer for cleaning and disinfection, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.3 part of tea catechins, 0.8 part of lecithin, 3.5 parts of rosemary extract, 1.5 parts of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 4.5 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 57.12 parts of water.
The preparation method of the hand sanitizer for cleaning and disinfection comprises the following steps:
(1) adding 57.12 parts of water, 25 parts of quillaja bark extract, 3 parts of chitin, 0.7 part of carrageen crispus extract and 0.4 part of hydrolyzed sclerotium rolfsii gum into a reaction kettle according to a ratio, heating to 80 ℃, and stirring at the speed of 150-200 RPM for 20-30 min until the mixture is completely dissolved to form a mixed solution;
(2) keeping the temperature of the mixed solution in the step (1), adding 3 parts of decyl glucoside and 0.18 part of citric acid, fully dissolving, stirring at 150-200 RPM, and keeping the temperature for 5 min;
(3) cooling to 38 ℃, adding 0.3 part of catechins of the camellia sinensis, 0.8 part of lecithin, 3.5 parts of rosemary extract, 1.5 parts of ginkgo leaf extract and 4.5 parts of surfactin sodium, stirring at the speed of 150-200 RPM and the temperature of 20-25 ℃, and uniformly stirring to obtain the finished product.
Example two
The embodiment provides a hand sanitizer for cleaning and disinfection, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.5 part of tea catechins, 0.5 part of lecithin, 2 parts of rosemary extract, 1 part of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 3 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 60.72 parts of water.
The preparation method of the hand sanitizer for cleaning and disinfection comprises the following steps:
(1) adding 60.72 parts of water, 25 parts of quillaja bark extract, 3 parts of chitin, 0.7 part of carrageen crispus extract and 0.4 part of hydrolyzed sclerotium rolfsii gum into a reaction kettle according to a ratio, heating to 80 ℃, and stirring at the speed of 150-200 RPM for 20-30 min until the mixture is completely dissolved to form a mixed solution;
(2) keeping the temperature of the mixed solution in the step (1), adding 3 parts of decyl glucoside and 0.18 part of citric acid, fully dissolving, stirring at 150-200 RPM, and keeping the temperature for 5 min;
(3) cooling to 38 ℃, adding 0.5 part of catechins of the camellia sinensis, 0.5 part of lecithin, 2 parts of rosemary extract, 1 part of ginkgo leaf extract and 3 parts of surfactin sodium, stirring at the speed of 150-200 RPM and the temperature of 20-25 ℃, and uniformly stirring to obtain the finished product.
EXAMPLE III
The embodiment provides a hand sanitizer for cleaning and disinfection, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.4 part of tea catechins, 1.0 part of lecithin, 4 parts of rosemary extract, 2 parts of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 5 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 55.32 parts of water.
The preparation method of the hand sanitizer for cleaning and disinfection comprises the following steps:
(1) adding 55.32 parts of water, 25 parts of quillaja bark extract, 3 parts of chitin, 0.7 part of carrageen crispus extract and 0.4 part of hydrolyzed sclerotium rolfsii gum into a reaction kettle according to a ratio, heating to 80 ℃, and stirring at the speed of 150-200 RPM for 20-30 min until the mixture is completely dissolved to form a mixed solution;
(2) keeping the temperature of the mixed solution in the step (1), adding 3 parts of decyl glucoside and 0.18 part of citric acid, fully dissolving, stirring at 150-200 RPM, and keeping the temperature for 5 min;
(3) cooling to 38 ℃, adding 0.4 part of catechins of camellia sinensis, 1.0 part of lecithin, 4 parts of rosemary extract, 2 parts of ginkgo leaf extract and 5 parts of surfactin sodium, stirring at the speed of 150-200 RPM and the temperature of 20-25 ℃, and uniformly stirring to obtain the finished product.
Control group 1
Natural cleaning and disinfecting two-in-one hand sanitizer and preparation method thereof
The natural hand sanitizer integrating cleaning and disinfection is prepared by the following steps: (1) adding 63.22 parts of water, 25 parts of quillaja bark extract, 3 parts of chitin, 0.7 part of carrageen crispus extract and 0.4 part of hydrolyzed sclerotium rolfsii gum into a reaction kettle according to the proportion, heating to 80 ℃, and stirring at 150-200 RPM for 20-30 min until the mixture is completely dissolved to form a mixed solution;
(2) keeping the temperature of the mixed solution in the step (1), adding 3 parts of decyl glucoside and 0.18 part of citric acid, fully dissolving, stirring at 150-200 RPM, and keeping the temperature for 5 min;
(3) and (3) cooling to 38 ℃, adding 4.5 parts of sodium surfactin, stirring at the speed of 150-200 RPM and the temperature of 20-25 ℃, and uniformly stirring to obtain a finished product.
The cost of each example was compared to a control for efficacy evaluation
Operation 1: before evaluation, the natural and cleaning two-in-one hand sanitizer is evaluated, the number of bacterial colonies per gram is less than 1000, and the bacterial colonies meet the light industry standard of the people's republic of China. Under the premise, the evaluation selects escherichia coli, staphylococcus aureus and yeast as main evaluation objects.
The experimenter uses modes such as soapy water, aseptic normal saline, alcohol in proper order to make both hands be in the super clean state, cultivates in above three kinds of colonies with both hands again and surveys its colony quantity, and the later equal amount of adding the control group + flowing water and wash and equal amount embodiment 1+ flowing water washes, and the left and right hands sample.
Results of colony culture inspection by left-hand and right-hand sampling of equivalent control group + running water washing versus equivalent example 1+ running water washing 60S
| Number of colonies | |
| Equivalent control group + running water rinse | 6 |
| Equivalent example 1+ running Water rinse | 1 |
Staphylococcus aureus was not detected and both Escherichia coli and yeast were greatly reduced.
Operation 2: the control group and the example 1 are respectively mixed with escherichia coli, staphylococcus aureus and yeast and cultured, the growth condition of colonies is observed, after 24 hours of culture, the observation result shows that no bacteria exist on the culture medium of the example 1, and bacteria appear on the culture medium of the control group.
As can be seen from the above experimental data, example 1 is superior to the control group in the bactericidal effect, and example 1 is a preferred embodiment of the present invention, and has a significant effect of having a cleaning effect and a disinfecting effect compared to control group 1.
Operation 3: the natural cleaning and disinfecting two-in-one hand sanitizer is used by selecting 20 people with different cleanliness degrees of hands under the same hand washing method at the same time, wherein 2 hands have slight wounds, 3 hands have skin which is easy to be allergic, 2 hands have slight molting phenomenon, and the rest of normal skin. After washing hands, 20 people all feed back that the cleaning power is excellent, and can wash greasy dirt, foaming power, foam stabilizing power and the like to the user without bringing unpleasant feeling in the process, and the feedback of a few mild hand injuries and molting persons does not deteriorate, inflammation and molting phenomenon of hands even improves. After the cleaning agent is used, unpleasant feelings such as over-drying and roughness after use can not occur, so that the cleaning agent is evaluated to have the moisture retention performance and really has the performance of combining natural cleaning and disinfection.
Claims (7)
1. The hand sanitizer for cleaning and disinfection is characterized by being prepared from the following raw materials in parts by weight: 25.0 to 30.0 parts of Quillaja bark extract, 0.25 to 0.5 part of tea catechins, 0.5 to 1.0 part of lecithin, 2.0 to 5.0 parts of rosemary extract, 1.0 to 2.0 parts of ginkgo leaf extract, 3.0 to 5.0 parts of chitin, 2.0 to 3.0 parts of decyl glucoside, 0.5 to 1.0 part of Chondrus crispus extract, 3.0 to 5.0 parts of sodium surfactin, 0.2 to 0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05 to 0.2 part of citric acid and 62.5 to 46.8 parts of water.
2. The hand sanitizer according to claim 1, which is prepared from the following raw materials in parts by weight: 25.0-28.0 parts of quillaja bark extract, 0.25-0.4 part of tea catechins, 0.7-1.0 part of lecithin, 2.5-4.0 parts of rosemary extract, 1.0-1.5 parts of ginkgo leaf extract, 3.0-4.0 parts of chitin, 2.5-3.0 parts of decyl glucoside, 0.6-0.95 part of carrageen crispus extract, 4.0-5.0 parts of sodium surfactin, 0.25-0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05-0.2 part of citric acid and 60.15-51.45 parts of water.
3. The hand sanitizer according to claim 2, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.3 part of tea catechins, 0.8 part of lecithin, 3.5 parts of rosemary extract, 1.5 parts of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 4.5 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 57.12 parts of water.
4. The hand sanitizer according to claim 2, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.5 part of tea catechins, 0.5 part of lecithin, 2 parts of rosemary extract, 1 part of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 3 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 60.72 parts of water.
5. The hand sanitizer according to claim 2, which is prepared from the following raw materials in parts by weight: 25.0 parts of quillaja bark extract, 0.4 part of tea catechins, 1.0 part of lecithin, 4 parts of rosemary extract, 2 parts of ginkgo leaf extract, 3 parts of chitin, 3 parts of decyl glucoside, 0.7 part of carrageen crispus extract, 5 parts of surfactin sodium, 0.4 part of hydrolyzed sclerotium rolfsii gum, 0.18 part of citric acid and 55.32 parts of water.
6. A preparation method of a hand sanitizer for cleaning and disinfection is characterized by comprising the following steps:
(1) adding water, Quillaja bark extract, chitin, Chondrus crispus extract and hydrolyzed sclerotium rolfsii gum into the sterilized reaction kettle according to the proportion, heating and dissolving at the temperature of 70-80 ℃, the stirring speed of 150-200 RPM and the stirring time of 20-30 min to form a mixed solution;
(2) continuously keeping the temperature of the mixed solution at 70-80 ℃, stirring at the speed of 150-200 RPM, then adding citric acid and decyl glucoside, stirring at the speed of 150-200 RPM, and keeping the temperature for 5 min;
(3) and (3) after the mixed solution is stirred and cooled to 35-40 ℃, the stirring speed is 200RPM, and the other components, namely tea catechins, lecithin, rosemary extract, ginkgo leaf extract and sodium surfactin are added, wherein the stirring speed is 150-200 RPM, and the temperature is 20-25 ℃.
7. A method of preparing a sanitizing hand sanitizer according to claim 6 wherein: the composition is prepared from the following raw materials in parts by weight: 25.0 to 30.0 parts of Quillaja bark extract, 0.25 to 0.5 part of tea catechins, 0.5 to 1.0 part of lecithin, 2.0 to 5.0 parts of rosemary extract, 1.0 to 2.0 parts of ginkgo leaf extract, 3.0 to 5.0 parts of chitin, 2.0 to 3.0 parts of decyl glucoside, 0.5 to 1.0 part of Chondrus crispus extract, 3.0 to 5.0 parts of sodium surfactin, 0.2 to 0.5 part of hydrolyzed sclerotium rolfsii gum, 0.05 to 0.2 part of citric acid and 62.5 to 46.8 parts of water.
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