CN112335891A - Oral formulation containing non-hydrolytic plant fiber and chitin - Google Patents
Oral formulation containing non-hydrolytic plant fiber and chitin Download PDFInfo
- Publication number
- CN112335891A CN112335891A CN202011196780.3A CN202011196780A CN112335891A CN 112335891 A CN112335891 A CN 112335891A CN 202011196780 A CN202011196780 A CN 202011196780A CN 112335891 A CN112335891 A CN 112335891A
- Authority
- CN
- China
- Prior art keywords
- chitin
- parts
- oral formulation
- fiber
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000835 fiber Substances 0.000 title claims abstract description 35
- 229920002101 Chitin Polymers 0.000 title claims abstract description 32
- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 238000009472 formulation Methods 0.000 title claims abstract description 25
- 230000003301 hydrolyzing effect Effects 0.000 title claims abstract description 12
- 239000000843 powder Substances 0.000 claims abstract description 22
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 7
- 235000013339 cereals Nutrition 0.000 claims abstract description 5
- 235000013325 dietary fiber Nutrition 0.000 claims abstract description 5
- 239000000796 flavoring agent Substances 0.000 claims abstract description 5
- 235000013355 food flavoring agent Nutrition 0.000 claims abstract description 5
- 235000012055 fruits and vegetables Nutrition 0.000 claims abstract description 5
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 5
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 5
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 4
- 239000003765 sweetening agent Substances 0.000 claims abstract description 4
- 235000013311 vegetables Nutrition 0.000 claims abstract description 3
- 241000196324 Embryophyta Species 0.000 claims description 24
- 244000269722 Thea sinensis Species 0.000 claims description 17
- 235000013616 tea Nutrition 0.000 claims description 11
- 239000007910 chewable tablet Substances 0.000 claims description 6
- 235000006468 Thea sinensis Nutrition 0.000 claims description 5
- 241000238557 Decapoda Species 0.000 claims description 4
- 229940068682 chewable tablet Drugs 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 235000000346 sugar Nutrition 0.000 claims description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 3
- 235000020279 black tea Nutrition 0.000 claims description 3
- 235000009569 green tea Nutrition 0.000 claims description 3
- 229920002261 Corn starch Polymers 0.000 claims description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- 229930195725 Mannitol Natural products 0.000 claims description 2
- 239000008120 corn starch Substances 0.000 claims description 2
- 239000008101 lactose Substances 0.000 claims description 2
- 239000000594 mannitol Substances 0.000 claims description 2
- 235000010355 mannitol Nutrition 0.000 claims description 2
- 235000020333 oolong tea Nutrition 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 235000010356 sorbitol Nutrition 0.000 claims description 2
- 235000020334 white tea Nutrition 0.000 claims description 2
- 235000019789 appetite Nutrition 0.000 abstract description 8
- 230000036528 appetite Effects 0.000 abstract description 8
- 235000013305 food Nutrition 0.000 abstract description 7
- 230000036186 satiety Effects 0.000 abstract description 7
- 235000019627 satiety Nutrition 0.000 abstract description 7
- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 238000002360 preparation method Methods 0.000 abstract description 3
- 150000002632 lipids Chemical class 0.000 abstract description 2
- 210000002784 stomach Anatomy 0.000 abstract description 2
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 description 13
- 229920002678 cellulose Polymers 0.000 description 13
- 230000000694 effects Effects 0.000 description 9
- 241000282414 Homo sapiens Species 0.000 description 6
- 239000003925 fat Substances 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 4
- 235000012054 meals Nutrition 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 230000009102 absorption Effects 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 230000000968 intestinal effect Effects 0.000 description 3
- 230000004580 weight loss Effects 0.000 description 3
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 2
- 229920001661 Chitosan Polymers 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 240000003553 Leptospermum scoparium Species 0.000 description 2
- 244000280244 Luffa acutangula Species 0.000 description 2
- 235000009814 Luffa aegyptiaca Nutrition 0.000 description 2
- 235000015459 Lycium barbarum Nutrition 0.000 description 2
- 208000008589 Obesity Diseases 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 235000019577 caloric intake Nutrition 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 201000001883 cholelithiasis Diseases 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000013872 defecation Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 102000038379 digestive enzymes Human genes 0.000 description 2
- 108091007734 digestive enzymes Proteins 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 235000003642 hunger Nutrition 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000020824 obesity Nutrition 0.000 description 2
- 230000009103 reabsorption Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 235000009852 Cucurbita pepo Nutrition 0.000 description 1
- 241000219104 Cucurbitaceae Species 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 229920002488 Hemicellulose Polymers 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020710 Hyperphagia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010033307 Overweight Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 229960004977 anhydrous lactose Drugs 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 239000003613 bile acid Substances 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000005200 bud stage Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004851 dishwashing Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 235000005686 eating Nutrition 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000037219 healthy weight Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 229960001375 lactose Drugs 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 235000021486 meal replacement product Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 235000020830 overeating Nutrition 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 201000002859 sleep apnea Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A23L33/22—Comminuted fibrous parts of plants, e.g. bagasse or pulp
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/198—Dry unshaped finely divided cereal products, not provided for in groups A23L7/117 - A23L7/196 and A23L29/00, e.g. meal, flour, powder, dried cereal creams or extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides an oral formulation containing non-hydrolytic plant fiber and chitin, and belongs to the technical field of health-care food. The formula comprises non-hydrolytic vegetable fiber, chitin, fruit and vegetable powder, protein powder, cereal powder, dietary fiber powder, sweetening agent, flavoring agent and excipient. When ingested in a quantity, the formulation suppresses appetite and causes a feeling of satiety, such as that caused by a "full" stomach. Therefore, the preparation is a dietary supplement which can suppress appetite, promote satiety, and maintain healthy blood lipids.
Description
Technical Field
The invention relates to the field of health care products, in particular to an oral formulation containing non-hydrolytic plant fiber and chitin.
Background
In modern society, due to the great improvement of living standard and bad living habits, diet irregularity of partial crowds, frequent overeating and lack of exercise cause imbalance of intake and consumption of body energy, abnormal catabolism of fat and fat in vivo, excessive accumulation of fat and overweight, and obesity. Obesity can not only cause excessive proud flesh in human body to affect body beauty, but also cause partial diseases, such as hypertension, hyperlipidemia, diabetes, coronary heart disease, cholelithiasis, sleep apnea, depression and the like.
The weight loss of meal replacement food is a healthy weight loss mode which is easily accepted by people at present, but the meal replacement products on the market are various in types and good in quality, the weight loss effect of some products is not obvious, and the weight loss is easy to rebound after the use is stopped. Some of the traditional Chinese medicine composition is also added with chemically synthesized additives or Chinese herbal medicine extracts, and certain toxic and side effects can be generated after long-term use, so that secondary damage is brought to the health of a human body. Some cause undesirable side effects such as anxiety, hyperactivity, etc.
To date, there has not been a low volume material that suppresses appetite and is satisfactory without causing undesirable side effects.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide an oral formulation which is small in size, strong in satiety effect, safe and reliable and does not cause adverse side effects.
The purpose of the invention is realized by the following technical scheme:
an oral formulation containing non-hydrolytic plant fiber and chitin, the oral formulation containing non-hydrolytic plant fiber and chitin, by weight, comprising: 0.5 to 20 parts of non-hydrolytic vegetable fiber, 0.01 to 10 parts of chitin, 0.01 to 10 parts of fruit and vegetable powder, 0.01 to 10 parts of protein powder, 0.01 to 10 parts of cereal powder, 0.01 to 10 parts of dietary fiber powder, 0.01 to 10 parts of sweetening agent, 0.01 to 5 parts of flavoring agent and 0.01 to 5 parts of excipient.
Preferably, the non-hydrolyzable plant fiber is 5 to 10 parts, and the chitin is 1 to 5 parts.
The non-hydrolytic plant fiber is a sclerenchyma tissue widely distributed in plants, is also a filamentous or floccule generated by combining cellulose and various nutrient substances, has the functions of supporting, connecting, wrapping, filling and the like on the plants, and is widely present in plant stalks, roots, fruits and shells.
The non-hydrolyzable plant fiber is a non-digestible material that includes cellulose, hemicellulose, lignin, pectin, and some non-cellulosic sugars. Plant fibers can have a variety of different characteristics, both in morphology and in tissue structure that change significantly as the plant grows mature. By the mature period of the plant, the plant fiber is already gelatinized, cornified and lignified. At this time, the plant fiber is insoluble in water and is not decomposed by human digestive enzymes, and is called as crude fiber. For example, tea leaves in the bud stage and towel gourds in the flowering stage both contain rich digestible fibers, and are delicious foods for people; the fiber of the tea tree is mature and aged, so the tea tree is not edible; the mature loofah is not edible, and the loofah is used as a dish washing tool. It is noted that both digestible and non-digestible crude fiber have unique lipid-lowering function, and are important and irreplaceable health foods for human beings.
Preferably, the non-hydrolysable plant fibres are selected from tea fibres.
Preferably, the tea fibres are selected from green tea fibres, black tea fibres, white tea fibres, oolong tea fibres, or mixtures of two or more thereof.
The tea fiber itself has almost no calorie, and the weight of the human body is not increased by taking a large amount of the tea fiber. Increasing the intake of dietary cellulose increases the frequency of chewing in the mouth and produces satiety with less caloric intake, thereby reducing caloric intake. Meanwhile, a large amount of cellulose can shorten the retention time of food in the intestinal tract, reduce the reabsorption of the intestinal tract and play a role in losing weight to a certain extent. In addition, cellulose reduces the activity of digestive enzymes in the pancreas and reduces the absorption of sugars, fats, and the like. Therefore, the high-cellulose food is often used as an ideal diet food.
If intestinal waste is retained, the re-absorption of the intestinal wall can result in the presence of harmful substances in the blood. When waste products are present in the blood, the waste products are discharged from the skin, and thus pimples, comedones, dark spots, etc. appear on the face. So that poor defecation can affect the beauty and fitness of the skin. The cellulose can accelerate gastrointestinal peristalsis, discharge excrement out of body quickly, reduce absorption of metabolic waste or poison by intestinal wall, and keep blood clean, thereby achieving the effect of beautifying.
In addition, cellulose can reduce reabsorption of bile acid, change food digestion speed and secretion of digestive secretion, and prevent cholelithiasis, duodenal ulcer, and ulcerative colitis. It is noted that the cellulose in tea leaves is not taken into the human body by drinking tea because it is insoluble in water, and the cellulose in tea leaves can be effectively utilized by drinking tea cellulose.
Preferably, the chitin is selected from shrimp chitin and crab chitin. Chitin (C8H13O5N) n, also known as Chitin, english name Chitin. Chitin is pale beige to white, soluble in concentrated hydrochloric acid/phosphoric acid/sulfuric acid/acetic acid, insoluble in alkali and other organic solvents, and also insoluble in water. Chitosan (chitosans), a deacetylated derivative of chitin, is insoluble in water and soluble in a fraction of dilute acid. Chitin can improve digestive absorption function, reduce intake of fat and cholesterol, lower blood pressure, regulate blood lipid, promote ulcer healing, enhance immunity, lower blood pressure, improve insulin utilization rate, and is beneficial for preventing and treating diabetes. The shells of shrimps and crabs contain abundant chitin, but are often discarded, and if the shells are utilized, the value of the shells is not lower than that of the meat.
Preferably, the excipient is selected from lactose, sugar, corn starch, mannitol, sorbitol.
Preferably, the oral formulation may be one or more of an optional chewable tablet, a granular formulation.
The invention has the beneficial effects that: the present invention provides an oral formulation comprising non-hydrolysable plant fibre and chitin, which when ingested in an amount which suppresses appetite and causes a feeling of satiety, for example, the feeling of satiety caused by a "full" stomach. Thus, the preparation is an effective means for suppressing appetite and controlling body weight.
Detailed Description
The technical solution of the present invention is described in detail below, but the scope of the present invention is not limited to the embodiments.
Example 1
Chewable tablets containing non-hydrolyzable plant fiber and chitin were prepared in the following manner.
Mixing green tea cellulose 15 g, chitin 10 g, fruit and vegetable powder 5 g, protein composite powder 5 g, cereal powder 5 g, dietary fiber powder 5 g, and anhydrous lactose 5 g. The resulting mass is granulated with a suitable wetting agent and the wet mass is then passed through a granulator equipped with a suitable screen. The wet mass is dried to a specified moisture content and then passed through a granulator equipped with a suitable screen. Suitable flavoring agents, artificial sweeteners and excipients are added to the dried granules. The product is then compressed into chewable tablets having a total weight of about 2 to about 2.5 grams using a three-quarter inch, chamfered edge, round flat die tooling.
Example 2
Solid granules containing non-hydrolyzable plant fibers and chitin were prepared in the following manner.
Fully mixing 20 g of black tea cellulose, 5 g of chitin, 10 g of fruit and vegetable powder, 10 g of protein composite powder, 10 g of cereal powder and 10 g of dietary fiber powder. The resulting mass is granulated with a suitable wetting agent and the wet mass is then passed through a granulator equipped with a suitable screen. The wet mass is dried to a specified moisture content and then passed through a granulator equipped with a suitable screen. Suitable flavoring agents, sweeteners and excipients are added to the dried granules. And then packaged into 2 to 10 g of meal replacement powder in the form of a solid granular preparation.
Example 3
The chewable tablet of example 1 was administered to the subject as follows. The chewable tablet is taken at about 5 pm every day for four consecutive days. The subjects noted a significant decrease in appetite and no hunger sensation several hours after use of the lozenge. The subject had a feeling of eating. No adverse or unpleasant sensation was noted and the subject did not experience any other effect during which no substantial defecation was found.
Example 4
The subjects took the solid particle formulation of example 2 daily before meals for four days. The subject felt no hunger. The subject had a lunch approximately 30 to 50 minutes after taking the meal replacement powder, and the subject indicated a significant reduction in appetite with less lunch than usual. The subject did not report adverse reactions or abnormal bowel movements.
From the foregoing examples 3 and 4, it has been demonstrated that oral formulations containing non-hydrolyzable plant fibers and chitin have appetite suppressing activity and induce satiety.
Claims (8)
1. An oral formulation containing non-hydrolytic plant fiber and chitin, which is characterized in that the oral formulation contains the non-hydrolytic plant fiber and the chitin, and comprises the following components in parts by weight: 0.5 to 20 parts of non-hydrolytic vegetable fiber, 0.01 to 10 parts of chitin, 0.01 to 10 parts of fruit and vegetable powder, 0.01 to 10 parts of protein powder, 0.01 to 10 parts of cereal powder, 0.01 to 10 parts of dietary fiber powder, 0.01 to 10 parts of sweetening agent, 0.01 to 5 parts of flavoring agent and 0.01 to 5 parts of excipient.
2. The oral formulation according to claim 1, wherein the non-hydrolyzable plant fiber is preferably 5 to 10 parts, and the chitin is preferably 1 to 5 parts.
3. The oral formulation of claim 1, wherein the non-hydrolyzable plant fiber is selected from the group consisting of tea fiber.
4. The oral formulation of claim 3, wherein the tea fiber is selected from green tea fiber, black tea fiber, white tea fiber, oolong tea fiber, or a mixture of two or more thereof.
5. The oral formulation of claim 1, wherein the chitin is selected from the group consisting of shrimp chitin and crab chitin.
6. The oral formulation according to claim 1, wherein said excipients are selected from lactose, sugar, corn starch, mannitol, sorbitol.
7. The oral formulation of claim 1, wherein the oral formulation is a chewable tablet.
8. The oral formulation of claim 1, wherein the oral formulation is a solid particulate formulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011196780.3A CN112335891A (en) | 2020-10-30 | 2020-10-30 | Oral formulation containing non-hydrolytic plant fiber and chitin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011196780.3A CN112335891A (en) | 2020-10-30 | 2020-10-30 | Oral formulation containing non-hydrolytic plant fiber and chitin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112335891A true CN112335891A (en) | 2021-02-09 |
Family
ID=74355842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011196780.3A Pending CN112335891A (en) | 2020-10-30 | 2020-10-30 | Oral formulation containing non-hydrolytic plant fiber and chitin |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112335891A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173829A (en) * | 2016-07-06 | 2016-12-07 | 武汉好多多生物科技有限公司 | A kind of processing method of ourishing rice flour |
| CN106262951A (en) * | 2016-08-31 | 2017-01-04 | 江苏阜丰生物科技有限公司 | A kind of dietary fiber chewable tablets and preparation method thereof |
| CN108936236A (en) * | 2018-06-20 | 2018-12-07 | 丹凤县商山丹水食品有限公司 | A kind of nutritional meal replacement powder and its processing method of high dietary-fiber |
| CN108968084A (en) * | 2018-06-28 | 2018-12-11 | 贵州省石阡正岩苔生态茶业有限公司 | A kind of preparation method of tealeaves dietary fiber |
-
2020
- 2020-10-30 CN CN202011196780.3A patent/CN112335891A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173829A (en) * | 2016-07-06 | 2016-12-07 | 武汉好多多生物科技有限公司 | A kind of processing method of ourishing rice flour |
| CN106262951A (en) * | 2016-08-31 | 2017-01-04 | 江苏阜丰生物科技有限公司 | A kind of dietary fiber chewable tablets and preparation method thereof |
| CN108936236A (en) * | 2018-06-20 | 2018-12-07 | 丹凤县商山丹水食品有限公司 | A kind of nutritional meal replacement powder and its processing method of high dietary-fiber |
| CN108968084A (en) * | 2018-06-28 | 2018-12-11 | 贵州省石阡正岩苔生态茶业有限公司 | A kind of preparation method of tealeaves dietary fiber |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101606704A (en) | A kind of dietary fiber food with multiple function | |
| CN100356867C (en) | Black edible fungus health food and its preparation method | |
| CN107467462A (en) | A kind of generation meal solid beverage for contributing to fat-reducing and preparation method thereof | |
| CN106723087A (en) | A kind of tablet containing kelp dietary fiber and preparation method thereof | |
| CN109329930A (en) | A kind of composition and preparation method thereof for promoting uric acid to reduce | |
| CN109549097A (en) | A kind of health caring noodles with functions of reducing sugar and reducing fat | |
| CN103054127B (en) | Cellulose effervescent tablet with weight reducing function | |
| CN108812792A (en) | A kind of sugar-free buckwheat biscuit | |
| JP3533181B2 (en) | Cocoa extract containing dietary fiber | |
| CN104012850A (en) | Dietary fiber nutrient paste and preparation method thereof | |
| CN112390899A (en) | Preparation method of blend of pregelatinized starch and pachyman alkaline hydrolysis fragment and application of blend in weight-reducing meal replacement food | |
| CN104054788B (en) | A kind of celery health-care biscuit | |
| CN102987402B (en) | Plateau natural plant food with balance nutrition and preparation method thereof | |
| CN112335891A (en) | Oral formulation containing non-hydrolytic plant fiber and chitin | |
| CN109090585A (en) | One kind relieves the effect of alcohol, protect stomach, protect liver, shield brain composition and preparation method thereof | |
| KR100503208B1 (en) | Diet-food composition | |
| JP2001269135A (en) | Nutritional composition capable of promoting body protein accumulation efficiency | |
| CN104305229B (en) | A kind of stem of noble dendrobium dietary fiber food and its processing method | |
| WO2006106888A1 (en) | Oral composition for promoting defecation containing patchouli oil and dietary fiber | |
| CN107536035A (en) | A kind of functional food containing ketone and application thereof | |
| CN113197305A (en) | Formula and preparation method of crude fiber composite solid food | |
| CN113397094A (en) | Soybean protein powder capable of reducing blood fat and blood sugar and preparation method thereof | |
| JP2009034017A (en) | Diet food | |
| CN111685332A (en) | Composition with fat-reducing, body-shaping and body-beautifying functions and preparation method thereof | |
| CN103829110B (en) | A kind of preparation method of the konjaku rice dumpling |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210209 |
|
| RJ01 | Rejection of invention patent application after publication |