CN112204020B - 二氧杂环丁烷化合物及其用于检测微生物的用途 - Google Patents
二氧杂环丁烷化合物及其用于检测微生物的用途 Download PDFInfo
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- CN112204020B CN112204020B CN201980035311.2A CN201980035311A CN112204020B CN 112204020 B CN112204020 B CN 112204020B CN 201980035311 A CN201980035311 A CN 201980035311A CN 112204020 B CN112204020 B CN 112204020B
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- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C07F9/02—Phosphorus compounds
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- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
- C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems
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- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/14—Streptococcus; Staphylococcus
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- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/22—Testing for sterility conditions
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
- G01N21/763—Bioluminescence
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- C12Q2304/00—Chemical means of detecting microorganisms
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- Proteomics, Peptides & Aminoacids (AREA)
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- Immunology (AREA)
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- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18174403 | 2018-05-25 | ||
| EP18174403.8 | 2018-05-25 | ||
| PCT/EP2019/063418 WO2019224338A1 (en) | 2018-05-25 | 2019-05-24 | Dioxetane compounds and their use for the detection of microorganisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112204020A CN112204020A (zh) | 2021-01-08 |
| CN112204020B true CN112204020B (zh) | 2023-11-14 |
Family
ID=62599426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980035311.2A Active CN112204020B (zh) | 2018-05-25 | 2019-05-24 | 二氧杂环丁烷化合物及其用于检测微生物的用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11649475B2 (https=) |
| EP (1) | EP3802511A1 (https=) |
| JP (1) | JP7462574B2 (https=) |
| KR (2) | KR20250052483A (https=) |
| CN (1) | CN112204020B (https=) |
| WO (1) | WO2019224338A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110944985B (zh) * | 2017-05-24 | 2022-12-13 | 特拉维夫大学拉玛特有限公司 | 用于蛋白酶的成像/检测的化学发光探针 |
| US20230094870A1 (en) * | 2020-02-19 | 2023-03-30 | Ramot At Tel-Aviv University Ltd. | Chemiluminescence probes for tuberculosis |
| WO2025079067A1 (en) * | 2023-10-10 | 2025-04-17 | Ramot At Tel-Aviv University Ltd. | Chemiluminescent array-based assay for rapid identification of bacteria and method of use |
| WO2025191551A1 (en) * | 2024-03-13 | 2025-09-18 | Ramot At Tel-Aviv University Ltd. | Phenoxy-dioxetanes-based chemiluminescence probes and uses thereof |
| CN119409748A (zh) * | 2025-01-06 | 2025-02-11 | 四川省医学科学院·四川省人民医院 | 一种N-乙酰-β-D-氨基葡萄糖酶的化学发光探针、试剂盒及其制备方法和应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017130191A1 (en) * | 2016-01-26 | 2017-08-03 | Ramot At Tel-Aviv University Ltd. | Chemiluminescent probes for diagnostics and in vivo imaging |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223402A (en) | 1990-08-30 | 1993-06-29 | Difco Laboratories | Method of detecting microbes utilizing chemiluminescent compound |
| EP1735621A4 (en) | 2004-04-14 | 2012-12-12 | Brij P Giri | NEW ULTRA-SENSITIVE CHEMIELUMINESCENSE SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES |
| WO2009139811A2 (en) | 2008-05-15 | 2009-11-19 | Tianxin Wang | Chemiluminescent methods and reagents for analyte detection |
| CN102183512B (zh) | 2011-02-15 | 2012-09-19 | 杭州师范大学 | 一种基于化学发光原理的活细胞检测方法 |
| JP2017505612A (ja) | 2014-01-17 | 2017-02-23 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | メタロ−β−ラクタマーゼを発現する細菌を検出するための6,7−トランスセファロスポリンに基づくプローブ |
| CN106279178B (zh) | 2016-07-18 | 2019-01-18 | 华东理工大学 | 耐碳青霉烯类抗生素病菌的荧光探针及合成方法与应用 |
| CN110944985B (zh) | 2017-05-24 | 2022-12-13 | 特拉维夫大学拉玛特有限公司 | 用于蛋白酶的成像/检测的化学发光探针 |
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2019
- 2019-05-24 EP EP19728340.1A patent/EP3802511A1/en active Pending
- 2019-05-24 KR KR1020257011217A patent/KR20250052483A/ko active Pending
- 2019-05-24 KR KR1020207037220A patent/KR20210013620A/ko active Pending
- 2019-05-24 CN CN201980035311.2A patent/CN112204020B/zh active Active
- 2019-05-24 JP JP2020567041A patent/JP7462574B2/ja active Active
- 2019-05-24 US US17/058,623 patent/US11649475B2/en active Active
- 2019-05-24 WO PCT/EP2019/063418 patent/WO2019224338A1/en not_active Ceased
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2023
- 2023-03-15 US US18/184,249 patent/US20230265480A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017130191A1 (en) * | 2016-01-26 | 2017-08-03 | Ramot At Tel-Aviv University Ltd. | Chemiluminescent probes for diagnostics and in vivo imaging |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7462574B2 (ja) | 2024-04-05 |
| KR20210013620A (ko) | 2021-02-04 |
| WO2019224338A1 (en) | 2019-11-28 |
| JP2021525273A (ja) | 2021-09-24 |
| CN112204020A (zh) | 2021-01-08 |
| KR20250052483A (ko) | 2025-04-18 |
| EP3802511A1 (en) | 2021-04-14 |
| US20230265480A1 (en) | 2023-08-24 |
| US11649475B2 (en) | 2023-05-16 |
| US20210214766A1 (en) | 2021-07-15 |
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