CN112156001A - Preparation method of smokeless moxa cone - Google Patents

Preparation method of smokeless moxa cone Download PDF

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Publication number
CN112156001A
CN112156001A CN202010856586.7A CN202010856586A CN112156001A CN 112156001 A CN112156001 A CN 112156001A CN 202010856586 A CN202010856586 A CN 202010856586A CN 112156001 A CN112156001 A CN 112156001A
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artemisiae argyi
folium artemisiae
moxa
smokeless
activated carbon
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于安伟
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Jiangsu Sancaiwuyan Medical Technology Development Co ltd
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Jiangsu Sancaiwuyan Medical Technology Development Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/06Devices for heating or cooling such points within cell-life limits

Abstract

The invention provides a preparation method of a smokeless moxa cone, which comprises the following steps: 1) preparing an active carbon column and an artemisia leaf extracting solution for later use; 2) fully soaking the activated carbon column in the folium artemisiae argyi extracting solution, and drying to obtain the smokeless folium artemisiae argyi column. Compared with the prior art, the smokeless moxa cone prepared by the method has the following unexpected technical effects: 1) can reduce the formation of moxa smoke in the burning process of moxa column when using, reduce indoor environmental pollution, green. 2) Because only the substance of the moxa is added in the preparation process, no chemical adhesive or other substances are added, and the effect is specific when the moxa is used. 3) The smokeless moxa cone prepared by the method can completely keep the active ingredients of the folium artemisiae argyi because the moxa is not carbonized at high temperature, and can achieve the effect of traditional moxibustion when in use.

Description

Preparation method of smokeless moxa cone
Technical Field
The invention relates to a preparation method of a smokeless moxa cone, and belongs to the technical field of traditional Chinese medicine.
Background
Moxibustion is one of the methods for treating and preventing diseases in traditional Chinese medicine, originates in ancient times in China, and is a treatment method which is wide in application range and achieves the purposes of preventing and treating diseases by stimulating acupuncture points or specific parts on the body surface with moxa heat generated by moxa materials made of folium artemisiae argyi, adjusting physiological and biochemical functions of human body disorder by exciting the activity of meridian qi, and playing the effects of promoting qi circulation, dredging collaterals, supporting yang, relieving depletion, promoting blood circulation, removing blood stasis, drawing out toxin, discharging heat, prolonging life, beautifying and the like. In the aspect of pharmacological research, the folium artemisiae argyi has the effects of resisting bacteria, viruses, asthma, cough, phlegm, allergy, bleeding and coagulation, enhancing the immune function and the like.
Folium Artemisiae Argyi (Folium Artemisiae Argyi) is herb of Artemisia of CompositaeLeaves (dry) of Artemisia argyi have effects of eliminating pathogenic factor, activating collaterals, dispelling cold, relieving pain, caring skin, and delaying aging[1]. Modern pharmacological research shows that the folium artemisiae argyi has the effects of resisting bacteria and viruses, relieving cough and asthma, protecting liver and gallbladder, resisting allergy, enhancing immunity and the like[2-5]
The folium Artemisiae Argyi water extractive solution has different degrees of inhibition on 3 kinds of bacteria. Compared with 3 kinds of bacteria, the antibacterial effect of the moxa leaf water extract on staphylococcus aureus is slightly better than that of escherichia coli and salmonella typhi B, and the antibacterial effect is enhanced along with the increase of the drug concentration. MICs of 3 kinds of bacteria were all 0.125g/mL[6]
Modern pharmacological research on antiallergic and antibacterial effects of folium Artemisiae Argyi decoction[7]. Therefore, the folium artemisiae argyi water decoction is used for treating skin itch and dermatitis, and can relieve the degree of blood vessel congestion, local swelling and pain, the degree of itch and eczema symptoms. The modern clinical external application of the folium artemisiae argyi has better effects on treating impetigo, pruritus vulvae, eczema scroti, skin eczema, scabies, verruca vulgaris and the like, and the clinical curative effect is consistent with the external application function of the folium artemisiae argyi for dispelling dampness and relieving itching. According to the experimental pharmacological experimental data and results, the characteristics and the law of the traditional Chinese medicine for treating corresponding diseases are discussed, the experimental support is provided for the external application of the folium artemisiae argyi for eliminating dampness and relieving itching, and the clinical application is supplemented to[8,9]. The experiment provides theoretical support for clinical external application of the folium artemisiae argyi, and provides a simple, effective and standardized treatment method for clinical skin pruritus and dermatitis.
The core material used in moxibustion is mainly a moxa cone containing folium artemisiae argyi components, and the existing moxa cone products mainly have the following defects:
1) the moxa cone on the market at present is directly filled with mugwort leaves, smoke can be generated in the combustion process, the smoke has the stimulation effect on asthma patients, asthma can be induced or the condition of the asthma can be aggravated, and the indoor environment is polluted;
2) in the production process of most smokeless moxa cones in the market, the moxa leaves need to be carbonized at high temperature, most effective components in the moxa leaves are lost in the process, and the obtained moxa cones only have heat effect when in use and cannot completely achieve the efficacy of traditional moxibustion.
3) Some chemical adhesives and aromatic substances are added into some smokeless moxa cones in the market, so that the smoke generated by burning the moxa cones is added with fragrance or other odors, but the fragrance is not necessarily suitable, and certain influence is exerted on the curative effect and the environment.
Chinese patent CN103393336B, entitled moxibustion type smokeless health-care Buddha incense, discloses moxibustion type smokeless health-care Buddha incense which is composed of the following raw materials in percentage by mass: 70-80% of charcoal powder, 8-10% of folium artemisiae argyi extract, 0.2-0.5% of nard extract, 0.1-0.3% of each component extract of angelica dahurica, asarum, notopterygium root, costus root, 10-20% of fennel and clove, 0.2-2% of sandalwood extract, and the total content of the components is 100%. Mixing and stirring extractive solutions of folium Artemisiae Argyi, rhizoma Nardostachyos, radix Angelicae Dahuricae, herba asari, Notopterygii rhizoma, radix aucklandiae, fructus Foeniculi and flos Caryophylli to obtain moxibustion extractive solution; adding a proper amount of water into the modified starch, stirring and dissolving uniformly to prepare a modified starch binder solution; mixing the carbon powder with the mixed solution of the moxibustion extract and the modified starch binder solution, stirring, molding, and drying to obtain incense blank; spraying the sandalwood extract on the incense blank uniformly to obtain the moxibustion type smokeless health Buddha incense finished product. The technical scheme has the following defects: the used extracting solution is more in variety, the folium artemisiae argyi extracting solution accounts for only 8-10% of the total content, and the moxibustion effect is not good; the used carbon powder is not easy to absorb and the content is only 70-80%.
[1] National pharmacopoeia committee, chinese pharmacopoeia (part) M. beijing: chinese medical science and technology press, 2010: 82-83.
[2] Pharmacological action and application of "caiping" folium artemisiae argyi [ J ]. shizhen national and medical drugs, 2001, 12 (12): 1137-1139.CAI Ping. the pharmacological action and application of Artemisiae argyi [ J ]. Lishizhen Medicine and Material medical Research, 2001, 12 (12): 1137-
[3]Adams M,Efferth T,Bauer R.Activity-guided isolation of scopoletin and isoscopoletin,the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells,from Artemisia argyi[J].Planta Medica,2006,72:862-864.
[4]Zeng K W,Wang S,Dong X,et al.Sesquiterpene dimer(DSF-52)from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-kappa B,JNK/p38 MAPKs and Jak2/Stat3 signaling pathways[J].Phytomedicine,2014,21(3):298-306.
[5]Seo J M,Kang H M,Son K H,et al.Antitumor activity of flavones isolated from Artemisia argyi[J].Planta Medica,2003,69:218-222.
[6]Wang Hua 1,2Zhouxiaoqiong (Zhouxiaoqiong)1,2Clock snow incense1At the corner of the Chinese character Wang1Liu refined1Zhang Qiu poem1In vitro bacteriostatic tests of the aqueous extract of artemisia leaf on 3 bacteria, heilongjiang veterinary, 2016(10 below): 168-169,172
[7] Liu Wei, Liu Lian, Yuanming, folium Artemisiae Argyi aqueous extract in vitro antibacterial test, Chinese pharmacist, 2009(8): 1159-1160
[8] Mao jun refined, miaoming three, establishment and perfection of traditional Chinese medicine functional pharmacodynamic spectrum, pharmacology and clinic of traditional Chinese medicine, 2011; 27(5) and 111 to 112
[9] Miaoming III, Yang bud, examination of the basic pharmacological action of the theory of drug properties, pharmacology and clinical use of Chinese herbs, 2011; 27 (6): (110-112)
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a preparation method of a smokeless moxa cone.
The technical scheme of the invention is as follows:
a preparation method of a smokeless moxa cone comprises the following steps:
1) preparing an active carbon column and an artemisia leaf extracting solution for later use; among them, the activated carbon column may be in various shapes including, but not limited to: cylindrical, rectangular, bar-shaped, etc.;
2) fully soaking the activated carbon column in the folium artemisiae argyi extracting solution, and drying to obtain the smokeless folium artemisiae argyi column.
Preferably, the first and second electrodes are formed of a metal,
in the step 1), the preparation method of the activated carbon column comprises the following steps: and (4) crushing, stripping, carbonizing and cutting the activated carbon to obtain the activated carbon column.
In the step 1), the preparation method of the folium artemisiae argyi extract liquid comprises the following steps: soaking folium Artemisiae Argyi in water, repeatedly extracting and concentrating to obtain folium Artemisiae Argyi extract.
In the step 2), the soaking time is 8-16h according to the different diameters and lengths of the moxa cone.
In the step 2), the drying may be natural drying or artificial drying. Naturally drying the mixture as follows: drying in the shade and in the sun; the artificial drying is as follows: vacuum drying, freeze drying, spray drying, microwave drying, air flow drying, infrared drying, high frequency drying, and the like.
More preferably still, the first and second liquid crystal compositions are,
in the preparation of the activated carbon column:
the active carbon is crushed and sieved for standby application before use;
the mesh number of the sieved screen is less than 200 meshes;
the crushed activated carbon is mixed and extruded into strips through an extruder according to different diameters;
carbonizing the strip-shaped activated carbon at the temperature of 1500-1800 ℃ for 8-12 h;
and after carbonization and cooling, cutting according to the requirements of diameter and length for later use.
The preparation of the folium artemisiae argyi extracting solution comprises the following steps:
the folium artemisiae argyi is high-quality folium artemisiae argyi which grows for 1-10 years;
the soaking time is 1-3h according to different addition amounts of the folium artemisiae argyi;
the extraction is carried out by boiling the folium artemisiae argyi in a repeated extraction process according to different addition amounts of the folium artemisiae argyi, and keeping slight boiling for 6-10 hours;
the concentration is carried out according to different concentration requirements of the extracting solution, the temperature is kept at 80-100 ℃ in the concentration process, and the concentration time is 6-12 h.
In the step 2), the drying adopts a vacuum drying method, the vacuum drying temperature is 30-50 ℃ (preferably 45 ℃), and the drying time is 8-24h according to different diameters and lengths of the moxa cone.
The smokeless moxa cone prepared by the invention can fully exert the effect of moxa in the combustion process, and the mechanism is as follows: when the moxa cone is burnt, the moxa can generate photothermal effect and moxibustion heat, such as specific wavelength light similar to human body and environmental temperature, can directly act on qi and blood of the human body, and is transmitted to the operation through meridians and collaterals, the blood is warmed and moved, the body state is adjusted and strengthened, and the moxibustion effect is finally achieved.
Compared with the prior art, the smokeless moxa column prepared by the method has the following unexpected technical effects through the synergistic effect of the activated carbon column and the folium artemisiae argyi extract:
1) can reduce the formation of moxa smoke in the burning process of moxa column when using, reduce indoor environmental pollution, green.
2) Because only the substance of the moxa is added in the preparation process, no chemical adhesive or other substances are added, and the effect is specific when the moxa is used.
3) The smokeless moxa cone prepared by the method can completely keep the active ingredients of the folium artemisiae argyi because the moxa is not carbonized at high temperature, and can achieve the effect of traditional moxibustion when in use.
Drawings
FIG. 1 is a flow chart of a method for preparing a smokeless moxa cone of the present invention.
Detailed Description
Example 1
The preparation method of the smokeless moxa cone comprises the following steps:
crushing the activated carbon, sieving the crushed activated carbon by a 60-mesh sieve, mixing the sieved activated carbon, and extruding the mixed activated carbon into strips by an extruder according to different diameters. Carbonizing the strip-shaped activated carbon at 1600 ℃ for 10h, cooling after the carbonization, and cutting according to the requirements of diameter and length.
Selecting 500g of 1-year-old high-quality folium artemisiae argyi, adding water to soak for 2h, adding the folium artemisiae argyi into an extraction tank to perform cooking extraction and concentration, firstly cooking to boiling, then keeping slightly boiling for 6h, keeping the temperature of 80 ℃ in the concentration process and concentrating for 6h according to the concentration requirement of an extracting solution.
Fully soaking the carbonized, cooled and cut activated carbon column in the folium artemisiae argyi extract for 10 hours according to different diameters and lengths of the folium artemisiae argyi column.
And (3) putting the soaked moxa cone into an electric heating vacuum drying oven, keeping the temperature at 45 ℃ for vacuum drying, and drying for 18h to ensure complete drying according to different diameters and lengths of the moxa cone.
Example 2
The preparation method of the smokeless moxa cone comprises the following steps:
crushing the activated carbon, sieving the crushed activated carbon by a 40-mesh sieve, mixing the sieved activated carbon, and extruding the mixed activated carbon into strips by an extruder according to different diameters. Carbonizing the strip-shaped activated carbon at 1500 ℃, carbonizing for 8h, cooling after the carbonization, and cutting according to the requirements of diameter and length.
Selecting 500g of 5-year-old high-quality folium artemisiae argyi, adding water to soak for 1h, adding the mixture into an extraction tank to perform cooking extraction and concentration, firstly cooking the mixture until the mixture is boiled, then keeping the mixture slightly boiling for 8h, keeping the temperature of 90 ℃ in the concentration process and concentrating the mixture for 8h according to the concentration requirement of an extracting solution.
Fully soaking the carbonized, cooled and cut activated carbon column in the folium artemisiae argyi extract for 8 hours according to different diameters and lengths of the folium artemisiae argyi column.
And (3) putting the soaked moxa cone into an electric heating vacuum drying oven, keeping the temperature at 45 ℃ for vacuum drying, and keeping the drying time for 8h for ensuring complete drying according to different diameters and lengths of the moxa cone.
Example 3
The preparation method of the smokeless moxa cone comprises the following steps:
crushing the activated carbon, sieving the crushed activated carbon by a 40-mesh sieve, mixing the sieved activated carbon, and extruding the mixed activated carbon into strips by an extruder according to different diameters. Carbonizing the strip-shaped activated carbon at 1800 ℃ for 12h, cooling after the carbonization is finished, and cutting according to the requirements of diameter and length.
Selecting 1000g of 10-year-old high-quality folium artemisiae argyi, adding water to soak for 3h, adding the folium artemisiae argyi into an extraction tank to perform cooking extraction and concentration, firstly cooking to boiling, then keeping slightly boiling for 10h, keeping the temperature of 100 ℃ in the concentration process and concentrating for 12h according to the concentration requirement of an extracting solution.
Fully soaking the carbonized, cooled and cut activated carbon column in the folium artemisiae argyi extract for 16 hours according to different diameters and lengths of the folium artemisiae argyi column.
And (3) putting the soaked moxa cone into an electric heating vacuum drying oven, keeping the temperature at 45 ℃ for vacuum drying, and keeping the drying time for 24 hours for ensuring complete drying according to different diameters and lengths of the moxa cone.
Example 4 Combustion test
Experimental materials:
the smokeless moxa columns prepared in examples 1 to 3 were used as experimental materials, and a conventional moxa column and an activated carbon column containing no extract of mugwort leaf were used as controls.
Traditional moxa cone has two kinds:
the first traditional moxa column is directly filled with folium artemisiae argyi or moxa wool, or is kneaded and extruded into moxa sticks or moxa columns by adding an adhesive; (preparation method refer to publication No. CN 111135068A published by 2020.05.12, entitled "preparation method of Chinese herbal medicine moxa stick")
The second traditional moxa column is prepared by directly making moxa sticks or moxa columns from folium artemisiae argyi after high-temperature carbonization, crushing, sieving, extrusion and drying. (preparation method refer to the invention patent of publication No. CN 105770096A, published as 2016.07.20, entitled smokeless moxa cone for moxibustion and its preparation method.)
The experimental method comprises the following steps:
the smokeless moxa sticks prepared in examples 1 to 3 were placed in the same hermetic platform with the same diameter and length as the conventional moxa sticks, and the two kinds of moxa sticks were ignited with an alcohol burner or a glow stick, respectively. When both of them were completely burned (i.e. the whole diameter surface of the moxa cone was completely burned), the smoke amount, carbon monoxide, PM10, PM2.5, formaldehyde, etc. were measured.
Specific combustion test methods are referenced in the following documents: chang Xiao Rong, orchid bud, Zhangshan, Shi Jia, Tan Jing, moxa stick burning test report [ J ] Guangming TCM, 2011, 26(9): 1801-.
The experimental results are as follows:
first traditional moxa cone combustion experimental data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Carbon monoxide PM10
1562ug/m3 0.23mg/m3 2000ppm 29.3℃ 57.8%RH 2.23ppm 546ppm 6545ug/m3
Second conventional moxa cone combustion experimental data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Carbon monoxide PM10
637ug/m3 0.19mg/m3 470ppm 28.9℃ 53%RH 1.7ppm 236ppm 988ug/m3
Example 1 smokeless moxa cone combustion experimental data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Carbon monoxide PM10
315ug/m3 0.17mg/m3 172ppm 27.6℃ 58.9%RH 1.02ppm 108ppm 460ug/m3
Example 2 smokeless moxa cone combustion experimental data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Carbon monoxide PM10
483ug/m3 0.19mg/m3 309ppm 29.3℃ 52.1%RH 1.34ppm 163ppm 614ug/m3
Example 3 smokeless moxa cone combustion experimental data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Oxygen generationCarbonization of carbon PM10
410ug/m3 0.18mg/m3 255ppm 28.7℃ 55.2%RH 1.16ppm 137ppm 523ug/m3
The combustion experimental data of the activated carbon column without the folium artemisiae argyi extract comprises the following data:
PM2.5 TVOC smoke and fog Temperature of Humidity Formaldehyde (I) Carbon monoxide PM10
584ug/m3 0.19mg/m3 479ppm 28.9℃ 53%RH 1.26ppm 167ppm 806ug/m3
And (4) experimental conclusion:
through the experiments and data, the smokeless moxa column prepared by the method disclosed by the invention has the advantages that the activated carbon column and the folium artemisiae argyi extract can act synergistically, the generation of moxa smoke in the combustion process of the moxa column is reduced, the irritation of smoke to a human body in the moxibustion process is avoided, the indoor environmental pollution is reduced, and the smokeless moxa column is green and environment-friendly. In addition, only one substance of the moxa is added into the smokeless moxa column prepared by the method, and no chemical adhesive is added. Meanwhile, the method avoids the carbonization of the Chinese mugwort leaves and well preserves the active ingredients of the Chinese mugwort leaves. Simple and safe use and is suitable for wide popularization.

Claims (8)

1. A preparation method of a smokeless moxa cone is characterized by comprising the following steps:
1) preparing an active carbon column and an artemisia leaf extracting solution for later use;
2) fully soaking the activated carbon column in the folium artemisiae argyi extracting solution, and drying to obtain the smokeless folium artemisiae argyi column.
2. The method for preparing a smokeless moxa column according to claim 1, wherein in the step 1), the method for preparing an activated carbon column comprises the following steps: and (4) crushing, stripping, carbonizing and cutting the activated carbon to obtain the activated carbon column.
3. The method for preparing a smokeless moxa cone according to claim 1, wherein in the step 1), the preparation method of the folium artemisiae argyi extract comprises the following steps: soaking folium Artemisiae Argyi in water, repeatedly extracting and concentrating to obtain folium Artemisiae Argyi extract.
4. The method for preparing smokeless moxa cone according to claim 1, wherein the soaking time in step 2) is 8-16h according to the diameter and length of the moxa cone.
5. The method for preparing a smokeless moxa cone according to claim 1, wherein the drying in step 2) is natural drying or artificial drying.
6. The method for preparing a smokeless moxa column according to claim 2, wherein the preparation of the activated carbon column comprises:
the active carbon is crushed and sieved for standby application before use;
the mesh number of the sieved screen is less than 200 meshes;
the crushed activated carbon is mixed and extruded into strips through an extruder according to different diameters;
carbonizing the strip-shaped activated carbon at the temperature of 1500-1800 ℃ for 8-12 h;
and after carbonization and cooling, cutting according to the requirements of diameter and length for later use.
7. The method for preparing a smokeless moxa cone according to claim 3, wherein the preparation of the folium artemisiae argyi extract comprises the following steps:
the folium artemisiae argyi is high-quality folium artemisiae argyi which grows for 1-10 years;
the soaking time is 1-3h according to different addition amounts of the folium artemisiae argyi;
the extraction is carried out by boiling the folium artemisiae argyi in a repeated extraction process according to different addition amounts of the folium artemisiae argyi, and keeping slight boiling for 6-10 hours;
the concentration is carried out according to different concentration requirements of the extracting solution, the temperature is kept at 80-100 ℃ in the concentration process, and the concentration time is 6-12 h.
8. The method for preparing a smokeless moxa cone according to claim 5,
in the step 2), the drying is carried out by adopting a vacuum drying method, the vacuum drying temperature is 30-50 ℃, and the drying time is 8-24h according to different diameters and lengths of the moxa cone.
CN202010856586.7A 2020-08-24 2020-08-24 Preparation method of smokeless moxa cone Pending CN112156001A (en)

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