CN107184638A - A kind of Chinese medicine smokeless moxa roll and preparation method thereof - Google Patents
A kind of Chinese medicine smokeless moxa roll and preparation method thereof Download PDFInfo
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract
The invention provides a kind of Chinese medicine smokeless moxa roll and preparation method thereof, it is related to Chinese medicine health-care technical field.The traditional Chinese medicine extraction composition includes any one in Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng extract or at least two combination and Folium Artemisiae Argyi extract.The traditional Chinese medicine extraction composition can be applied in all kinds of cosmetic health products and method, play effect of promoting blood circulation and removing blood stasis, dredging the channel, physical fitness and nourishing and health preserving.The Chinese medicine smokeless moxa roll prepared using the traditional Chinese medicine extraction composition, on the basis of original moxa stick active ingredient is retained, has Chinese medicine health-care effect concurrently.
Description
Technical field
The present invention relates to Chinese medicine health-care technical field, in particular to a kind of Chinese medicine smokeless moxa roll and preparation method thereof.
Background technology
Traditional puncture can produce a large amount of smog when carrying out moxibustion, and these smog are unrelated with effect of moxa-moxibustion, but cause
The pollution of indoor environment, reduces the experience of moxibustion, or even causes to health certain harm.In view of this, smokeless Chinese mugwort
Bar, smokeless moxibustion post are gradually by big well-established, as traditional moxa stick substitute.Need to end in the production process of smokeless moxa roll
Leaf or batten high temperature carbonization, in this course most active ingredients in folium artemisiae argyi can lose, the moxa stick so obtained makes
Used time only has fuel factor, and effect of traditional puncture can not be fully achieved.
Chinese herbal medicine is widely approved by practice for thousands of years and cognition.Know that natural resources of Chinese medicinal materials sum reaches
10000 liang of over thousands of kinds, wherein, pseudo-ginseng, the Radix Astragali, the bark of eucommia, ginseng are all warm-natured and and have in the effect of physical fitness, nourishing
Herbal medicine.Principle active component in pseudo-ginseng, the Radix Astragali, the bark of eucommia, ginseng is glycoside material, but the hydrophilic not lipophilic of glycoside material,
Molecular weight is larger, there is the problem of being difficult to absorbing transmission from skin, thus be all the time with the oral principal mode to absorb,
It is difficult to be absorbed into vivo by the external application mode such as smearing or massaging in vitro.
How the active ingredient in Chinese herbal medicine to be blended with moxa-moxibustion and other health-care methods, the focus as exploitation.
The content of the invention
The first object of the present invention is to provide a kind of preparation method of Chinese medicine smokeless moxa roll, and the traditional Chinese medicine extraction composition can
Applied in all kinds of cosmetic health products and method, effect of promoting blood circulation and removing blood stasis, dredging the channel, physical fitness and nourishing and health preserving is played.
A kind of traditional Chinese medicine extraction composition, including following raw material：Notogineng Extract, Astragalus Root P.E, eucommia ulmoides extracts or people
Any one in conopsea extraction or at least two composition and Folium Artemisiae Argyi extract.
Folium Artemisiae Argyi extract is containing abundant volatile oil and Flavonoid substances, with antibacterial, antiviral, eliminating the phlegm, relieving cough and asthma, anti-
The multiple efficacies such as allergy, anticoagulation, complement activation and calmness.
Notogineng Extract main component is arasaponin, and long-term use can improve microcirculation, promoting blood circulation and removing obstruction in channels, softening blood
Pipe, lowering blood pressure and blood fat, treatment liver fibrosis etc..
Astragalus Root P.E main component is astragaloside and astragalus polyose, and it has enhancing body's immunity, liver protection, profit
Urine, anti-aging, decompression and wide antibacterial action.
Effect of Squama Manis extract is blood circulation promoting and dispersing pathogen accumulation, stimulate the menstrual flow lower breast, anti-stain in solid.
Angelica extract：Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.
Eucommia ulmoides extracts main component is glycoside and phenylpropanoids, can remove internal rubbish, reinforcement human body thin
Born of the same parents' metabolism, prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol, reduction body fat, recover blood vessel
Elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system and the effect for improving white blood cell.
Ginseng extract is that Hydrolysis kinetics are formed from the root, stem and leaf of ginseng, and it is rich in 18 kinds of ginseng saponinses,
Ginsenoside can substantially suppress lipid peroxide in brain and liver and be formed, and reduce the content of lipofuscin in cerebral cortex and liver, together
When can also increase the content of superoxide dismutase and catalase in blood, with antioxidation.In addition, ginseng soap
Partial monosomy saponin(e such as rg3, rg2, rb1, rb2, rd, rc, re, rg1 in glycosides etc. can reduce interior free yl to some extent
Content.Ginsenoside can delay nerve cell aging and reduce memory impairment, and be closed with stablizing membrane structure and increasing protein
Into effect, memory ability can be improved.
By the way that Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract eucommia ulmoides extracts or ginseng are carried
Take thing to be used in combination with Folium Artemisiae Argyi extract, play the synergy of various bulk drugs, can be by the traditional Chinese medicine extraction composition of preparation
Arbitrarily it is added in all kinds of cosmetic health products, plays effect of promoting blood circulation and removing blood stasis, dredging the channel, physical fitness and nourishing and health preserving.
Preferably, above-mentioned traditional Chinese medicine extraction composition, including following raw material：Folium Artemisiae Argyi extract, Notogineng Extract, astragalus extraction
Thing, Squama Manis extract, angelica extract eucommia ulmoides extracts and ginseng extract.
Preferably, in above-mentioned traditional Chinese medicine extraction composition, Folium Artemisiae Argyi extract is that 65-85 parts by weight, Notogineng Extract are 10-15
Parts by weight, Astragalus Root P.E are 3-8 parts by weight, Squama Manis extract 3-8 parts by weight, angelica extract 5-10 parts by weight, the bark of eucommia
Extract is 5-15 parts by weight and ginseng extract 2-6 parts by weight.
Preferably, in above-mentioned traditional Chinese medicine extraction composition, Folium Artemisiae Argyi extract is that 65 parts by weight, Notogineng Extract are 12 weight
Part, Astragalus Root P.E be that 6 parts by weight, Squama Manis extract are that 5 parts by weight, angelica extract are that 5 parts by weight, eucommia ulmoides extracts are
5 parts by weight and the parts by weight of ginseng extract 2.
By further optimizing the proportion relation of each raw material, the synergy of each raw material can be further improved,
Strengthen using effect.
Preferably, above-mentioned Folium Artemisiae Argyi extract is, by water-ethanol heating and refluxing extraction, ethanol to be concentrated after filtering and obtains big portion
It is divided into the active ingredient of volatile oil and Flavonoid substances.
Preferably, extracted respectively by pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia or ginseng first and obtain glucosides, then by acid
Hydrolyze method hydrolyzing glucosidic bonds, remove and hydrolysate aglycon are obtained after glycosyl, dry after obtain Notogineng Extract, Astragalus Root P.E,
Eucommia ulmoides extracts or ginseng extract.
In the present invention, by the sugar in the active ingredient glycoside material of pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia and ginseng
Base is removed, and has obtained the aglycon corresponding with active ingredient.Aglycon has good lipophilicity, can be dissolved in lipid component
In, its transdermal capability is greatly improved compared with polyglycoside molecule.In moxa-moxibustion and massage, skin heart and body surface point are upset
While, aglycon can enter internal through skin, and synergy is played with moxa-moxibustion and massage.Promoting blood circulation is played in use
Stagnation resolvation, dredging the channel, effect of physical fitness and nourishing and health preserving.
Preferably, the content of glucosides is no more than the 5% of gross weight in traditional Chinese medicine extraction composition.
The preparation method of above-mentioned traditional Chinese medicine extraction composition, comprises the following steps：
By any in Notogineng Extract, Astragalus Root P.E, eucommia ulmoides extracts or ginseng extract or at least two groups
Conjunction is mixed with Folium Artemisiae Argyi extract, obtains traditional Chinese medicine extraction composition.
Preferably, preparing the process of Folium Artemisiae Argyi extract includes：Folium artemisiae argyi is placed in solvent, is heated to reflux, is filtrated to get and carries
Liquid is taken, extract solution is dried to obtain Folium Artemisiae Argyi extract.
Preferably, in the step of preparing Folium Artemisiae Argyi extract, the solvent is water-ethanol solvent.
Preferably, the mass ratio of the water-ethanol is 1: 1.
Preferably, it is 2-4h that duration is hydrolyzed in acid hydrolysis；
Preferably, ultrasonic extraction extraction time is 35-50min；
Preferably, extraction process, which is adopted, is extracted with ethyl acetate；
Preferably, the content of glucosides is no more than the 5% of gross weight in the traditional Chinese medicine extraction composition.
Preferably, Notogineng Extract, Astragalus Root P.E, pangolin, Radix Angelicae Sinensis, eucommia ulmoides extracts or ginseng extract are prepared
Process includes：Pseudo-ginseng, the Radix Astragali, the bark of eucommia or ginseng are crushed respectively first, glycoside material is extracted with ultrasonic extraction, then by acid
Hydrolyze method hydrolyzing glucosidic bonds, remove and hydrolysate aglycon are obtained after glycosyl, and Notogineng Extract, the Radix Astragali are obtained after extracting, drying
Extract, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng extract.
Preferably, it is 2-4h that duration is hydrolyzed in acid hydrolysis.
Preferably, extraction process, which is adopted, is extracted with ethyl acetate.
Preferably, the content of glucosides is no more than the 5% of gross weight in the traditional Chinese medicine extraction composition.
Notogineng Extract, Astragalus Root P.E, Squama Manis extract, the Radix Angelicae Sinensis of the method preparation provided using the present invention are extracted
Thing, eucommia ulmoides extracts or ginseng extract, using Hydrolyze method by the sugar on the polyglycoside molecule in pseudo-ginseng, the Radix Astragali, the bark of eucommia and ginseng
Base is removed, and has obtained the aglycon corresponding with active ingredient.Aglycon has good lipophilicity, can be dissolved in lipid component
In, its transdermal capability is greatly improved compared with polyglycoside molecule.In moxa-moxibustion and massage, skin heart and body surface point are upset
While, aglycon can enter internal through skin, and synergy is played with moxa-moxibustion and massage.The Chinese medicine prepared by this method
Extract composition and contain substantial amounts of aglycon effective constituents, the active ingredient of different crude drug sources plays synergy, used
During play effect of promoting blood circulation and removing blood stasis, dredging the channel, physical fitness and nourishing and health preserving.
A kind of Chinese medicine smokeless moxa roll, the Chinese medicine smokeless moxa roll is prepared by following steps：By folium artemisiae argyi frying, grinding
Infiltrated with being placed in after shaping in the solvent containing above-mentioned traditional Chinese medicine extraction composition, Chinese medicine smokeless moxa roll is obtained after drying.
The dissolving of above-mentioned traditional Chinese medicine extraction composition is infiltrated smokeless moxa roll by the present invention in a solvent, the nothing after being carbonized using frying
The property adsorbing Chinese medicine of cigarette moxa stick porous surface extracts the active ingredient of composition, so as to obtain Chinese medicine smokeless moxa roll.Use
When light after Chinese medicine smokeless moxa roll, the active ingredient volatilized in traditional Chinese medicine extraction composition by breathing and transdermal effect enter body
It is interior, play treatment and health effect.The Chinese medicine smokeless moxa roll that the present invention is provided solves popular smokeless moxa stick and damaged in process of production
The problem of losing active ingredient, possesses the advantage of traditional moxa stick, is more attached with pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia and ginseng
Chinese herbal medicine effect.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.It is unreceipted specific in embodiment
Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or the unreceipted production firm person of instrument, be
The conventional products that can be obtained by commercially available purchase.
The traditional Chinese medicine extraction composition that embodiment 1-3 is provided, which is prepared by the following method, to be obtained, and difference is each raw material
Content it is different：
1) Folium Artemisiae Argyi extract is prepared：Folium artemisiae argyi is placed in the water-ethanol solvent that mass ratio is 1: 1, heated back at 55-65 DEG C
Flow 1.5-2.5h, be filtrated to get extract solution, extract solution is dried to obtain Folium Artemisiae Argyi extract；
2) Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng are prepared
Extract：After pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia or ginseng are crushed, 35-50min is extracted using ultrasonic extraction and obtained
To the component containing glucosides, 2-4h is hydrolyzed with acid-hydrolysis method and removes the hydrolysate aglycon obtained after the glycosyl of glucosides, acetic acid is used
Ethyl ester is extracted and dried after aglycon, is obtained Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, the bark of eucommia and is carried
Take thing or ginseng extract；
3) traditional Chinese medicine extraction composition is prepared：By the Notogineng Extract of above-mentioned preparation, Astragalus Root P.E, Squama Manis extract,
Any or at least two combination is mixed with Folium Artemisiae Argyi extract in angelica extract, eucommia ulmoides extracts or ginseng extract, is obtained
To traditional Chinese medicine extraction composition.
Claims (7)
1. a kind of Chinese medicine smokeless moxa roll and preparation method thereof, it is characterised in that including following raw material：Notogineng Extract, the Radix Astragali are carried
Take any one in thing, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng extract or at least two combination
With Folium Artemisiae Argyi extract.
2. a kind of Chinese medicine smokeless moxa roll according to claim 1 and preparation method thereof, it is characterised in that including following original
Material：Folium Artemisiae Argyi extract, Notogineng Extract, Astragalus Root P.E, eucommia ulmoides extracts and ginseng extract.
3. a kind of Chinese medicine smokeless moxa roll according to claim 1 or 2 and preparation method thereof, it is characterised in that folium artemisiae argyi is extracted
Thing is that 65-85 parts by weight, Notogineng Extract are that 10-15 parts by weight, Astragalus Root P.E are 3-8 parts by weight, Squama Manis extract 3-8
Parts by weight, angelica extract 5-10 parts by weight, eucommia ulmoides extracts are 5-15 parts by weight and ginseng extract 2-6 parts by weight；
Preferably, Folium Artemisiae Argyi extract is that 65 parts by weight, Notogineng Extract are that 12 parts by weight, Astragalus Root P.E are 6 parts by weight, Chuan Shan
First extract is that 5 parts by weight, angelica extract are that 5 parts by weight, eucommia ulmoides extracts are 5 parts by weight and the parts by weight of ginseng extract 2；
Preferably, extracted respectively by pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia or ginseng first and obtain glucosides, then by sour water solution
Method hydrolyzing glucosidic bonds, remove and hydrolysate aglycon are obtained after glycosyl, and Notogineng Extract, Astragalus Root P.E, the bark of eucommia are obtained after drying
Extract or ginseng extract；
Preferably, the content of glucosides is no more than the 5% of gross weight in traditional Chinese medicine extraction composition.
4. a kind of a kind of Chinese medicine smokeless moxa roll as described in claim any one of 1-3 and preparation method thereof, it is characterised in that bag
Include following steps：
By in Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng extract
Any or at least two combinations are mixed with Folium Artemisiae Argyi extract, obtain traditional Chinese medicine extraction composition.
5. a kind of Chinese medicine smokeless moxa roll according to claim 4 and preparation method thereof, it is characterised in that
Preparing the process of Folium Artemisiae Argyi extract includes：Folium artemisiae argyi is placed in solvent, is heated to reflux, is filtrated to get extract solution, extract solution
It is dried to obtain Folium Artemisiae Argyi extract；
Preferably, the solvent is water-ethanol solvent；
Preferably, the mass ratio of the water-ethanol is 1: 1；
Preferably, the temperature that is heated to reflux is 70-85 DEG C, and the time is 2-3.5h；
Preferably, the temperature that is heated to reflux is 75 DEG C, and the time is 2h；
Preferably, Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng are prepared
The process of extract includes：Pseudo-ginseng, the Radix Astragali, pangolin, Radix Angelicae Sinensis, the bark of eucommia or ginseng are crushed respectively first, ultrasonic extraction is used
Glycoside material is extracted, then by acid-hydrolysis method hydrolyzing glucosidic bonds, removes and hydrolysate aglycon is obtained after glycosyl, through extraction, is dried
After obtain Notogineng Extract, Astragalus Root P.E, Squama Manis extract, angelica extract, eucommia ulmoides extracts or ginseng extract；
Preferably, it is 2-4h that duration is hydrolyzed in acid hydrolysis；
Preferably, ultrasonic extraction extraction time is 35-50min；
Preferably, extraction process, which is adopted, is extracted with ethyl acetate；
Preferably, the content of glucosides is no more than the 5% of gross weight in the traditional Chinese medicine extraction composition.
6. a kind of Chinese medicine smokeless moxa roll and preparation method thereof, it is characterised in that the Chinese medicine smokeless moxa roll passes through following steps system
It is standby to obtain：
By the solvent for the traditional Chinese medicine extraction composition being placed in after folium artemisiae argyi frying, grinding and shaping described in any one of 1-5 containing claim
Middle infiltration, Chinese medicine smokeless moxa roll is obtained after drying.
7. a kind of Chinese medicine smokeless moxa roll according to claim 6 and preparation method thereof, it is characterised in that the solvent of infiltration
The content of middle traditional Chinese medicine extraction composition is 10-40 weight %；
Preferably, the content of traditional Chinese medicine extraction composition is 25 weight % in the solvent of infiltration；
Preferably, infiltrating time is 15-60min；
Preferably, the solvent is ethanol.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108030670A (en) * | 2018-01-24 | 2018-05-15 | 平邑泰奉药材进出口有限公司 | A kind of smokeless moxibustion yellow mud ball and preparation method thereof |
| CN112156001A (en) * | 2020-08-24 | 2021-01-01 | 江苏三才五妍医疗科技发展有限公司 | Preparation method of smokeless moxa cone |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106109524A (en) * | 2016-08-16 | 2016-11-16 | 陶然 | A kind of Chinese medicine extraction compositions and preparation method thereof, Chinese medicine smokeless moxa roll and Chinese medicine massage oil |
| CN106474364A (en) * | 2016-09-28 | 2017-03-08 | 黄耀丹 | A kind of smokeless moxa roll treating dysmenorrhea |
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| CN106109524A (en) * | 2016-08-16 | 2016-11-16 | 陶然 | A kind of Chinese medicine extraction compositions and preparation method thereof, Chinese medicine smokeless moxa roll and Chinese medicine massage oil |
| CN106474364A (en) * | 2016-09-28 | 2017-03-08 | 黄耀丹 | A kind of smokeless moxa roll treating dysmenorrhea |
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| CN108030670A (en) * | 2018-01-24 | 2018-05-15 | 平邑泰奉药材进出口有限公司 | A kind of smokeless moxibustion yellow mud ball and preparation method thereof |
| CN108030670B (en) * | 2018-01-24 | 2020-04-28 | 平邑泰奉药材进出口有限公司 | Smokeless moxibustion yellow mud pill and preparation method thereof |
| CN112156001A (en) * | 2020-08-24 | 2021-01-01 | 江苏三才五妍医疗科技发展有限公司 | Preparation method of smokeless moxa cone |
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Application publication date: 20170922 |