CN107998250A - A kind of compound bruises and sprains medicinal liquor and preparation method thereof - Google Patents

A kind of compound bruises and sprains medicinal liquor and preparation method thereof Download PDF

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Publication number
CN107998250A
CN107998250A CN201711189421.3A CN201711189421A CN107998250A CN 107998250 A CN107998250 A CN 107998250A CN 201711189421 A CN201711189421 A CN 201711189421A CN 107998250 A CN107998250 A CN 107998250A
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parts
cream powder
powder
rhizome
wine
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Inventor
刘颖伸
谢明军
申巍
程桂广
周彬
桂跃
陈亮
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Kunming University of Science and Technology
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Kunming University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis

Abstract

The present invention relates to a kind of compound bruises and sprains medicinal liquor, belong to health-care medicated technical field, the compound bruises and sprains medicinal liquor, is made by the component of following mass parts:500~600 parts of 20~30 parts of scythian lamb rhizome cream powder, 20~30 parts of anisetree bark cream powder, 20~30 parts of rhizome of davallia cream powder, 15~20 parts of teasel root cream powder, 15~20 parts of pseudo-ginseng cream powder, 15~20 parts of Paris polyphylla cream powder, 10~15 parts of oldenlandia diffusa cream powder, 10~15 parts of the root bark of white mulberry, 10~15 parts of safflower and base liquor;The present invention by by extracts such as scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia diffusa, the root bark of white mulberry, safflowers according to theory of traditional Chinese medical science, scientific compatibility, function of human body is adjusted on the whole, so as to reach hemostasis callus, promoting blood circulation to remove blood stasis, anti-inflammatory go to swell, strengthening the muscles and bones and other effects.

Description

A kind of compound bruises and sprains medicinal liquor and preparation method thereof
Technical field
The present invention relates to a kind of compound bruises and sprains medicinal liquor and preparation method thereof, belong to health-care medicated technical field.
Background technology
Traumatic injury refer mainly to because fall flutter, impact etc. caused by soft tissue injury, wound swelling pain, skin and flesh breakage go out Blood, also including tumble injury incised wound etc..Main pharmacological stops up stagnant, blood for hemostasis and holds one's breath resistance, therefore using pain, swelling mainly to show.Control Treat suitable filling liver kidney, strengthening the bones and muscles, promoting blood circulation and removing obstruction in channels, relaxing muscles and tendons promoting the circulation of qi.The medicinal liquor or medicine of existing a variety for the treatment of traumatic injuries in the prior art Water, ZHONGHUA DIEDA WAN, blood-activating and pain-stopping capsules, Typhonium flagelliforme (Lodd.) Blume powder, Yunnan Baiyao bonesetting liquid, BOGU SHUI, SHANGKE DIEDA PIAN, dragon's blood arogel Capsule, stretch muscle capsule, powdered medicine for coaptation is controlled with pseudo-ginseng blood-circulation-invigovating cream etc., curative effect is slow.
Scythian lamb rhizome is the rhizome of Dicksoniaceae plant Cibotium barometz.Scythian lamb rhizome rhizome starch-containing 30% or so.Chain fern Rhizome starch-containing up to 48.5%, and class containing tannin.Rhizome is starch-containing and aspidinol;The pubescence of rhizome contains tannin and pigment.Gold Golden yellow fine hair, is good hemostatic on hair rhizoma cibotii plant.At wounds streamed blood, fine hair is stained with, is bled at once with regard to that can stop. Root-like stock also has filling liver kidney, diuresis and other effects.Rhizoma cibotii category strong muscles and bones medicine, has the disease that muscles and bones is not good for pair for the treatment of and health care Recast is used.Cure mainly stiff lumbar vertebra pain, it is impossible to pitching, the disease such as sufficient knee weakness and lumbago due to wind-wetness evil.There is temperature compensation to take the photograph effect admittedly, treatment frequent micturition, The enuresis, makes essence, with inferior.
Anisetree bark is also Cortex Illicii, Cortex schizophragmatis integrifolii radicis, Chinese hydrangeavine root-bark, belongs to Magnoliaceae.Its component 0.30%-0.71% containing volatile oil, Inside have:α-and nopinene, lauro lene, 1, 8-Cineole, linalool, safrole, camphor, Bronyl acetate, laurene etc. 28 into. Rheumatic arthritis can be treated;Lumbar muscle strain;Centipde-bite,《Xinhua's book on Chinese herbal medicine outline》, bark:Acrid flavour, it is puckery, warm-natured, it is slightly poisonous.Have Dispeling wind and dehumidification, the function of promoting qi circulation and relieving pain.
The rhizome of davallia, alias:Precipice ginger, rock connect ginger, delevay drynaria, meat it is broken mend, stone is broken mends, flying apsaras mouse, Niu Feilong, sudden wind, flies Moth grass.Polypodiales, Davalliaceae pteridophyte.Its medicinal efficacy is:1. The strong bone of kidney tonifying:It can promote absorption of the bone to calcium, improve Blood calcium and serum phosphorus levels, are conducive to bone calcification and bone salts is formed;2. anti-medicine poison:Originally water decoction is built up one's health by taking tonic to kanamycins and streptomysin Caused toxicity has obvious detoxicating functions, can mitigate toxic action of the kanamycins to cochlea, to the ototoxicity of medicine There is certain prevention effect, protect kidney, infringement of the kanamycins to kidney can be reduced;3. reducing blood lipid, antithrombotic:The rhizome of davallia is more Sugar lime, steroidal lactone and flavanone glycosides play the role of reducing serum cholesterol.Especially it is more prominent with the effect of more sugar limes Go out;4. cardiac effect:Rhizome of davallia flavanone glycosides has cardiac effect, can make the increase of rabbit myocardial contractive power, the rhythm of the heart is regular, is direct Act on cardiac muscle, and Non nervous system;5. protecting liver and detoxication:The rhizome of davallia can activate liver drug enzyme, mitigate or release medicine to liver Infringement, there is protecting liver and detoxication.6. kidney tonifying, invigorates blood circulation, hemostasis:Kidney deficiency chronic diarrhea and pain in the back are controlled, arthralgia pain due to rheumatism, dentalgia, tinnitus, falls Flash frustrate, bone fracture, appendicitis, alopecia areata, corn.
Teasel root, original name " Resurrection pill ", also known as shaven head.Its slightly warm in nature, it is bitter, pungent;Return liver and kidney channel.There are filling liver kidney, strengthening tendons Bone, continuous injured, stop the effect of uterine bleeding, available for treatment kidney deficiency and liver, soreness and weakness of waist and knees, arthralgia pain due to rheumatism, injury of tendon and muscle fracture, uterine bleeding, tire The illnesss such as leakage, injury from falling down.
Pseudo-ginseng, alias pseudo-ginseng powder are invaluable.It is warm-natured, sweet and slightly bitter taste.Rich in notoginsenoside, notoginseng polysaccharide, dencichine, Huang Ketone active ingredient, has hemostasis, promoting blood circulation and removing blood stasis, detumescence ding-tong, strengthening by means of tonics, antifatigue, resist oxygen lack, anti-aging, reducing blood lipid, drop Blood pressure, improve the effect such as body's immunity.
Paris polyphylla, is liliaceous plant Yunnan Rhizoma Paridis or the dry rhizome of paris polyphylla.Its bitter, cold nature;It is slightly poisonous. There is clearing heat and detoxicating a, swelling and pain relieving, the effect of cool liver is calmed the frightened, be usually used in furunculosis carbuncle swells, abscess of throat, snakebite and bugbite, the pain of injury caused by falling and tumbling, Convulsion.
Oldenlandia diffusa, alias:HERBA HEDYOTIS DIFFUSAE, tang Huang, snake needle grass, Radix Picriae felterrae, two leaf humulus, white flower cross are careless, sharp knife is careless, A, waterplantain ottelia herb, snake Lei grass, crane tongue grass, hang down loosely draft to be annual.It is its patent medicine bitter, light, it is cold in nature.Primary efficacy is clear Thermal detoxification, medicinal powder for relieving pain knot, promoting urination and removing dampness.Outstanding kind treatment all kinds inflammation.In clinical practice, if finding, oldenlandia diffusa is matched somebody with somebody 5 is proper, can treat a variety of diseases.
The root bark of white mulberry, Morus machaka or arbor, high 3--15m.Bark canescence.Pharmacology is made:1. sedation and analgesia acts on, The extract of the fat-soluble solvents such as the petroleum ether of the root bark of white mulberry, ether, ethyl acetate gives mouse intravenous, can reduce the spontaneous work of mouse It is dynamic, and have anticonvulsant effect;2. anti-inflammatory effect, root bark of white mulberry water extract gathers to Oral Administration in Rats or injection Carrageenan and Portugal Swollen feet caused by sugar has inhibitory action;3. antibacterial action, root bark of white mulberry decoction has staphylococcus aureus stronger suppression Effect;Also there is slight inhibitory action to typhoid bacillus and shigella flexneri.
Safflower, alias:Red blue flower, thorn safflower, composite family, safflower platymiscium, dry tubular flower is orange red, and floral tube is narrow thin, Apex 5 is split, and sliver is narrow linear, and flower pesticide yellow, is unified into pipe, is higher by outside sliver, its center has column cap to expose.Tool is special fragrant Gas, mildly bitter flavor.With flower piece is long, color is scarlet, the soft person of matter is preferred.With invigorate blood circulation, stasis eliminatings analgesic.Controlling through closing, abdominal mass are difficult Production, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.
The content of the invention
Complicated for above-mentioned drug ingredient existing in the prior art, the slow problem of curative effect, the present invention provides a kind of compound bruise Sprain medicinal liquor and preparation method thereof, the present invention is by by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, long-noded pit viper The extracts such as tongue grass, the root bark of white mulberry, safflower are according to theory of traditional Chinese medical science, and scientific compatibility, adjusts function of human body on the whole, so as to reach only Blood callus, promoting blood circulation to remove blood stasis, anti-inflammatory go to swell, strengthening the muscles and bones and other effects.Ultrasonic wave auxiliary reflux extraction of the present invention at the same time I.e. active ingredient in Chinese medicine, micro constitutent and heat-sensitive ingredients will not be destroyed can improve extracting efficiency well to technology again And ultrasonic wave auxiliary reflux extraction equipment cost is low, easy to operate, applied widely.
Compound bruises and sprains medicinal liquor of the present invention, is made by the component of following mass parts:20~30 parts of scythian lamb rhizome cream powder, 20~30 parts of maple skin cream powder, 20~30 parts of rhizome of davallia cream powder, 15~20 parts of teasel root cream powder, 15~20 parts of pseudo-ginseng cream powder, Paris polyphylla cream 15~20 parts of powder, 10~15 parts of oldenlandia diffusa cream powder, 10~15 parts of the root bark of white mulberry, 10~15 parts of safflower and base liquor 500~600 Part.
The base liquor is alcoholic strength>50% pure grain fermented wine or edible alcohol.
This compound bruises and sprains externally used medicinal liquor is added to warm bubbly water foot.
A kind of preparation method of compound bruises and sprains medicinal liquor, comprises the following steps that:
(1) powder processed:Respectively by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia diffusa, Sang Bai Skin, safflower crush and 60 mesh that sieve, then with the edible ethanol that mass fraction is 70~80% respectively to the powder material of each component -60 The reflux extraction of ultrasonic wave assisted decompression is carried out, wherein the mass volume ratio of each component powder and solution is 1g:10~15mL, extraction Time is 1~2h, 55~60 DEG C of extraction temperature, with filtered through gauze leaching liquor and takes filtrate after extraction, filter residue is soaked again Carry, filter, merge 2 filtrates and mix, by mixed liquor again by centrifugal treating, centrifuged supernatant is concentrated, that is, be prepared into each The cream powder of component;
(2) batch mixing:20~30 parts of scythian lamb rhizome cream powder, 20~30 parts of anisetree bark cream powder, the bone that step (1) is prepared It is broken to paste up 20~30 parts of powder, 15~20 parts of teasel root cream powder, 15~20 parts of pseudo-ginseng cream powder, 15~20 parts of Paris polyphylla cream powder, oldenlandia Careless 10~15 parts of cream powder, 10~15 parts of root bark of white mulberry cream powder, 10~15 parts of safflower cream powder are mixed to obtain mixture;
(3) soak:The mixture that step (2) is obtained is put into togerther in hermetically sealed can with mass parts for 500~600 parts of base liquors Immersion obtains crude drug wine in 15 days;
(4) ageing is aging:The crude drug wine that step (3) obtains is put into be sealed and stored 1 month in wine vat and obtains wine body;
(5) wine liquid for being clarified the wine body that step (4) obtains again by membrane filtration, envelope after being poured into bottle Mouthful, then heating water bath 30min, you can obtain finished wine.
The beneficial effects of the invention are as follows:
(1) present invention is by by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia diffusa, Sang Bai The extracts such as skin, safflower are according to theory of traditional Chinese medical science, and scientific compatibility, adjusts function of human body on the whole, so as to reach hemostasis callus, work Blood dissipates the stasis of blood, anti-inflammatory goes to swell, strengthening the muscles and bones and other effects.
(2) ultrasonic wave auxiliary reflux microwave leaching technology of the present invention will not destroy active ingredient in Chinese medicine, micro- Amount component and heat-sensitive ingredients can improve extracting efficiency well again and this ultrasonic wave auxiliary reflux extraction equipment into This is low, easy to operate, applied widely.
Brief description of the drawings
Fig. 1 is the process flow chart of the present invention.
Embodiment
The present invention is described in further detail below by drawings and examples, but protection scope of the present invention is not limited to In the content.
Embodiment 1
The compound bruises and sprains medicinal liquor, is made by the component of following mass parts:Scythian lamb rhizome cream powder 20g, anisetree bark cream powder 20g, rhizome of davallia cream powder 20g, teasel root cream powder 15g, pseudo-ginseng cream powder 15g, Paris polyphylla cream powder 15g, oldenlandia diffusa cream powder 10g, Sang Bai Skin 10g, safflower 10g and base liquor 500g.
As shown in Figure 1, for the preparation method process flow chart of the compound bruises and sprains medicinal liquor, it is comprised the following steps that:
(1) powder processed:Respectively by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia grass meal, Sang Bai Skin, safflower crush and 60 mesh that sieve, then with concentration is that 70wt% edible ethanols carry out ultrasonic wave assisted decompression to each component powder Reflux extraction, the wherein powder of each component and the mass volume ratio of edible ethanol is 1:10g/mL, ultrasonic power are 2000W, extraction time 1h, extraction temperature are 55 DEG C, and 6 layers of filtered through gauze are used after extraction, filtrate is taken, filter residue is soaked again Carry, filter, merge 2 filtrates and simultaneously mix, by mixed liquor again by centrifugal treating, by centrifuged supernatant vacuum-concentrcted, i.e., It is prepared into the cream powder (no alcohol) of each component;
(2) batch mixing:Scythian lamb rhizome cream powder 20g, anisetree bark cream powder 20g, the rhizome of davallia cream powder that step (1) is prepared 20g, teasel root cream powder 15g, pseudo-ginseng cream powder 15g, Paris polyphylla cream powder 15g, oldenlandia diffusa cream powder 10g, root bark of white mulberry cream powder 10g, safflower Cream powder 10g is mixed to obtain mixture;
(3) soak:The mixture that step (2) is obtained and 500g base liquors (alcoholic strength is 60% pure grain fermented wine) one Rise to be put into soak 15 days in hermetically sealed can and obtain crude drug wine;
(4) ageing is aging:The crude drug wine that step (3) obtains is put into be sealed and stored 1 month in wine vat and obtains wine body;
(5) wine liquid for being clarified the wine body that step (4) obtains again by membrane filtration, envelope after being poured into bottle Mouthful, then heating water bath 30min is that can obtain finished wine.
The compound bruises and sprains externally used medicinal liquor, effect are preferable.
Embodiment 2
The compound bruises and sprains specific medicinal liquor formula, is made by the component of following mass parts:Scythian lamb rhizome cream powder 30g, Maple skin cream powder 30g, rhizome of davallia cream powder 30g, teasel root cream powder 20g, pseudo-ginseng cream powder 20g, Paris polyphylla cream powder 20g, oldenlandia diffusa cream powder 15g, root bark of white mulberry 15g, safflower 15g and base liquor 600g.
As shown in Figure 1, for the preparation method of the compound bruises and sprains specific medicinal liquor formula, it is comprised the following steps that:
(1) powder processed:Respectively by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia grass meal, Sang Bai Skin, safflower crush and 60 mesh that sieve, then with concentration is that 80wt% edible ethanols carry out ultrasonic wave assisted decompression to each component powder Reflux extraction, the wherein powder of each component and the mass volume ratio of edible ethanol is 1:15g/mL, ultrasonic power are 2000W, extraction time 2h, extraction temperature are 60 DEG C, and 6 layers of filtered through gauze are used after extraction, filtrate is taken, filter residue is soaked again Carry, filter, merge 2 filtrates and simultaneously mix, by mixed liquor again by centrifugal treating, by centrifuged supernatant vacuum-concentrcted, i.e., It is prepared into the cream powder (no alcohol) of each component;
(2) batch mixing:Scythian lamb rhizome cream powder 30g, anisetree bark cream powder 30g, the rhizome of davallia cream powder that step (1) is prepared 30g, teasel root cream powder 20g, pseudo-ginseng cream powder 20g, Paris polyphylla cream powder 20g, oldenlandia diffusa cream powder 15g, root bark of white mulberry cream powder 15g, safflower Cream powder 15g is mixed to obtain mixture;
(3) soak:The mixture that step (2) obtains is put into togerther in hermetically sealed can with 600g base liquors (edible alcohol) and is soaked Obtain crude drug wine within 15 days;
(4) ageing is aging:The crude drug wine that step (3) obtains is put into be sealed and stored 1 month in wine vat and obtains wine body;
(5) wine liquid for being clarified the wine body that step (4) obtains again by membrane filtration, envelope after being poured into bottle Mouthful, then heating water bath 30min is that can obtain finished wine.
The compound bruises and sprains medicinal liquor is added to warm bubbly water foot, and effect is preferable.
Embodiment 3
The compound bruises and sprains specific medicinal liquor formula, is made by the component of following mass parts:Scythian lamb rhizome cream powder 25g, Maple skin cream powder 25g, rhizome of davallia cream powder 25g, teasel root cream powder 17g, pseudo-ginseng cream powder 17g, Paris polyphylla cream powder 17g, oldenlandia diffusa cream powder 13g, root bark of white mulberry cream powder 13g, safflower cream powder 13g and base liquor 560g.
As shown in Figure 1, the preparation method of the compound bruises and sprains specific medicinal liquor formula, it is comprised the following steps that:
(1) powder processed:Respectively by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia grass meal, Sang Bai Skin, safflower crush and 60 mesh that sieve, then with concentration is that 75wt% edible ethanols carry out ultrasonic wave assisted decompression to each component powder Reflux extraction, the wherein powder of each component and the mass volume ratio of edible ethanol is 1:12g/mL, ultrasonic power are 2000W, extraction time 1.5h, extraction temperature are 58 DEG C, and 6 layers of filtered through gauze are used after extraction, filtrate is taken, filter residue is soaked again Carry, filter, merge 2 filtrates and simultaneously mix, by mixed liquor again by centrifugal treating, by centrifuged supernatant vacuum-concentrcted, i.e., It is prepared into the cream powder (no alcohol) of each component;
(2) batch mixing:Scythian lamb rhizome cream powder 25g, anisetree bark cream powder 25g, the rhizome of davallia cream powder that step (1) is prepared 25g, teasel root cream powder 17g, pseudo-ginseng cream powder 17g, Paris polyphylla cream powder 17g, oldenlandia diffusa cream powder 13g, root bark of white mulberry cream powder 13g, safflower Cream powder 13g is mixed to obtain mixture;
(3) soak:The mixture that step (2) obtains is put into togerther in hermetically sealed can with 560g base liquors (edible alcohol) and is soaked Obtain crude drug wine within 15 days;
(4) ageing is aging:The crude drug wine that step (3) obtains is put into be sealed and stored 1 month in wine vat and obtains wine body;
(5) wine liquid for being clarified the wine body that step (4) obtains again by membrane filtration, envelope after being poured into bottle Mouthful, then heating water bath 30min is that can obtain finished wine.

Claims (4)

1. a kind of compound bruises and sprains medicinal liquor, it is characterised in that be made by the component of following mass parts:Scythian lamb rhizome cream powder 20~ 30 parts, 20~30 parts of anisetree bark cream powder, 20~30 parts of rhizome of davallia cream powder, 15~20 parts of teasel root cream powder, 15~20 parts of pseudo-ginseng cream powder, 15~20 parts of Paris polyphylla cream powder, 10~15 parts of oldenlandia diffusa cream powder, 10~15 parts of the root bark of white mulberry, 10~15 parts of safflower and base liquor 500 ~600 parts.
2. compound bruises and sprains medicinal liquor according to claim 1, it is characterised in that:The base liquor is alcoholic strength>50% Pure grain fermented wine or edible alcohol.
3. compound bruises and sprains medicinal liquor according to claim 1, it is characterised in that:External application is added to warm bubbly water foot.
4. the preparation method of the compound bruises and sprains medicinal liquor described in claim 1 or 2 or 3, it is characterised in that comprise the following steps that:
(1) powder processed:Respectively by scythian lamb rhizome, anisetree bark, the rhizome of davallia, teasel root, pseudo-ginseng, Paris polyphylla, oldenlandia diffusa, the root bark of white mulberry, red Pollen it is broken and sieve 60 mesh, then with concentration be 70~80wt% edible ethanol the powder material of each component -60 is surpassed respectively The reflux extraction of sound wave assisted decompression, the wherein mass volume ratio of each component powder and edible ethanol are 1:10~15g/mL, extraction Time is 1~2h, and 55~60 DEG C of extraction temperature after extraction, with filtered through gauze, takes filtrate, filter residue is extracted again, is filtered, and is closed And 2 filtrates and mix, by mixed liquor again by centrifugal treating, centrifuged supernatant is concentrated, that is, is prepared into the cream powder of each component;
(2) batch mixing:20~30 parts of scythian lamb rhizome cream powder, 20~30 parts of anisetree bark cream powder, the rhizome of davallia that step (1) is prepared 20~30 parts of cream powder, 15~20 parts of teasel root cream powder, 15~20 parts of pseudo-ginseng cream powder, 15~20 parts of Paris polyphylla cream powder, oldenlandia diffusa cream 10~15 parts of powder, 10~15 parts of root bark of white mulberry cream powder, 10~15 parts of safflower cream powder are mixed to obtain mixture;
(3) soak:The mixture that step (2) obtains is put into togerther in hermetically sealed can with mass parts for 500~600 parts of base liquors and is soaked Obtain crude drug wine within 15 days;
(4) ageing is aging:The crude drug wine that step (3) obtains is put into be sealed and stored 1 month in wine vat and obtains wine body;
(5) wine liquid for being clarified the wine body that step (4) obtains again by membrane filtration, sealing after being poured into bottle, Heating water bath 30min again, you can obtain finished wine.
CN201711189421.3A 2017-11-24 2017-11-24 A kind of compound bruises and sprains medicinal liquor and preparation method thereof Pending CN107998250A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101669991A (en) * 2009-10-10 2010-03-17 江泽平 Gendarussa wine and manufacturing method and application thereof
CN102949500A (en) * 2011-08-22 2013-03-06 天津尖峰弗兰德医药科技发展有限公司 Externally-applied traditional Chinese medicinal preparation used for foot sprains, and its preparation method
CN103877157A (en) * 2014-04-21 2014-06-25 张超 Chinese medicament for bone setting and preparation method of Chinese medicament

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101669991A (en) * 2009-10-10 2010-03-17 江泽平 Gendarussa wine and manufacturing method and application thereof
CN102949500A (en) * 2011-08-22 2013-03-06 天津尖峰弗兰德医药科技发展有限公司 Externally-applied traditional Chinese medicinal preparation used for foot sprains, and its preparation method
CN103877157A (en) * 2014-04-21 2014-06-25 张超 Chinese medicament for bone setting and preparation method of Chinese medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
陶德林: "正交法优选复方骨碎补接骨片提取工艺的研究", 《中国现代应用药学》 *

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