CN112120955A - Antibacterial moisturizing cosmetic and application thereof - Google Patents
Antibacterial moisturizing cosmetic and application thereof Download PDFInfo
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- CN112120955A CN112120955A CN202011006515.4A CN202011006515A CN112120955A CN 112120955 A CN112120955 A CN 112120955A CN 202011006515 A CN202011006515 A CN 202011006515A CN 112120955 A CN112120955 A CN 112120955A
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- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 44
- 239000002537 cosmetic Substances 0.000 title claims abstract description 31
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 19
- 239000000725 suspension Substances 0.000 claims abstract description 25
- 239000002562 thickening agent Substances 0.000 claims abstract description 24
- 239000004094 surface-active agent Substances 0.000 claims abstract description 21
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229940057950 sodium laureth sulfate Drugs 0.000 claims abstract description 16
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical group [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 claims abstract description 16
- 229920001577 copolymer Polymers 0.000 claims abstract description 15
- 150000002148 esters Chemical class 0.000 claims abstract description 15
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 14
- 229930006000 Sucrose Natural products 0.000 claims abstract description 14
- 239000003906 humectant Substances 0.000 claims abstract description 14
- 239000005720 sucrose Substances 0.000 claims abstract description 14
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 12
- 239000008101 lactose Substances 0.000 claims abstract description 12
- 239000004332 silver Substances 0.000 claims abstract description 11
- 229910052709 silver Inorganic materials 0.000 claims abstract description 11
- 102000008186 Collagen Human genes 0.000 claims abstract description 10
- 108010035532 Collagen Proteins 0.000 claims abstract description 10
- 229920001436 collagen Polymers 0.000 claims abstract description 10
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims abstract description 9
- 239000011259 mixed solution Substances 0.000 claims description 35
- 238000003756 stirring Methods 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical group [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 18
- 230000003385 bacteriostatic effect Effects 0.000 claims description 18
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 12
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims description 12
- 229920002261 Corn starch Polymers 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 9
- 239000008120 corn starch Substances 0.000 claims description 9
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 9
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 9
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 9
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 5
- 239000003086 colorant Substances 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical group O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 claims description 5
- 229940091173 hydantoin Drugs 0.000 claims description 5
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 5
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 5
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 5
- 239000003463 adsorbent Substances 0.000 claims description 4
- 125000003118 aryl group Chemical group 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- 230000002335 preservative effect Effects 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 238000004090 dissolution Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000003205 fragrance Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 abstract description 24
- 239000006260 foam Substances 0.000 abstract description 12
- 238000005187 foaming Methods 0.000 abstract description 4
- 238000012360 testing method Methods 0.000 description 29
- 230000000052 comparative effect Effects 0.000 description 18
- 239000000499 gel Substances 0.000 description 15
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical group [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 239000004480 active ingredient Substances 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 108010022355 Fibroins Proteins 0.000 description 2
- 206010040880 Skin irritation Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 235000015110 jellies Nutrition 0.000 description 2
- 239000008274 jelly Substances 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000036556 skin irritation Effects 0.000 description 2
- 231100000475 skin irritation Toxicity 0.000 description 2
- 238000013112 stability test Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- CONKBQPVFMXDOV-QHCPKHFHSA-N 6-[(5S)-5-[[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]methyl]-2-oxo-1,3-oxazolidin-3-yl]-3H-1,3-benzoxazol-2-one Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)C[C@H]1CN(C(O1)=O)C1=CC2=C(NC(O2)=O)C=C1 CONKBQPVFMXDOV-QHCPKHFHSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229920006243 acrylic copolymer Polymers 0.000 description 1
- 230000002052 anaphylactic effect Effects 0.000 description 1
- 239000000022 bacteriostatic agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000007705 chemical test Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000007863 gel particle Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000012430 stability testing Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses an antibacterial moisturizing cosmetic, and relates to the technical field of cosmetics. The antibacterial moisturizing cosmetic comprises the following components in parts by weight: 12-28 parts of surfactant, 2-2.2 parts of suspension thickening agent, 0.01-0.2 part of skin conditioner and 0.03-0.3 part of humectant; the suspension thickening agent is acrylic acid (ester) copolymer, the surfactant is sodium laureth sulfate and disodium cocoyl amphodiacetate, the skin conditioner is silver, and the humectant is soluble collagen, lactose and sucrose. Meanwhile, the antibacterial shower gel containing the suspended particles provided by the invention is high in foaming speed and rich in foam, and the produced body is less in bubbles and stable in particle suspension.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to an antibacterial moisturizing cosmetic and application thereof.
Background
99.9 percent of the shower gel sold in the market at present is white liquid or transparent liquid, is easy to foam, has rich foam, is too common, and cannot meet the requirements of modern young people. Meanwhile, the traditional shower gel is not clean after false slide rinsing, dry and sensitive after rinsing and does not keep moisture. And because of the suspension system, the particles are easy to sink, are not easy to foam, are not rich in foam, and have more bubbles in the material body.
Pearlescent particles or other types of particles are added in the same type on the market, and due to a suspension system, the particles are easy to sink and not easy to foam, the foam is not abundant, and bubbles are particularly abundant in the material body.
Disclosure of Invention
Based on the above, the invention aims to overcome the defects of the prior art and provide the bacteriostatic moisturizing cosmetic which is suspensible, has high foaming speed and abundant foam, and is less in bubbles and stable in particle suspension in the produced body.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows: an antibacterial moisturizing cosmetic comprises the following components in parts by weight: 12-28 parts of surfactant, 2-2.2 parts of suspension thickening agent, 0.01-0.2 part of skin conditioner and 0.03-0.3 part of humectant;
the suspension thickening agent is acrylic acid (ester) copolymer, the surfactant is sodium laureth sulfate and disodium cocoyl amphodiacetate, the skin conditioner is silver, and the humectant is soluble collagen, lactose and sucrose.
The antibacterial moisturizing cosmetic provided by the invention has the advantages that a formed suspension system is stable, the foaming speed is high, the foam is rich, and a special particle is provided, wherein the special particle is wrapped with the fibroin, so that the activity of the effective components is preserved, and the slow release is realized, and the skin irritation is reduced.
Preferably, the antibacterial moisturizing cosmetic comprises the following components in parts by weight: 12-20 parts of surfactant, 2-2.2 parts of suspension thickening agent, 0.01-0.05 part of skin conditioner and 0.1-0.2 part of humectant;
the weight part of acrylic acid (ester) copolymer in the suspension thickener is 2-2.2 parts, and the weight ratio of sodium laureth sulfate to disodium cocoyl amphodiacetate in the surfactant is sodium laureth sulfate: 10-20 parts of cocoyl amphodiacetate disodium: 2-8; the weight part of the silver in the skin conditioner is 0.01-0.05 part; the humectant comprises the following components in parts by weight: sucrose ═ 0.01-0.1: 0.01-0.1: 0.01-0.1.
The acrylic acid (ester) copolymer is used as a suspension thickening agent, and the wrapped moisture-retaining particles of the active ingredients are uniformly distributed in the shower gel, so that the slow-release active ingredients are accurately controlled, the anaphylactic and irritant reactions caused by the fact that the active ingredients are directly added into a body are reduced, and the shower gel is milder.
Preferably, the antibacterial moisturizing cosmetic comprises the following components in parts by weight: 16.5 parts of surfactant, 2.1 parts of suspension thickening agent, 0.03 part of skin conditioner and 0.16 part of humectant;
the weight part of acrylic acid (ester) copolymer in the suspension thickener is 2.1 parts, and the weight ratio of sodium laureth sulfate to disodium cocoyl amphodiacetate in the surfactant is sodium laureth sulfate: cocoyl amphodiacetate disodium 10.5: 6; the skin conditioner comprises 0.03 part by weight of silver, and the humectant comprises soluble collagen, lactose and sucrose in a weight ratio of: lactose: sucrose ═ 0.1: 0.03: 0.03.
the particles for wrapping the active ingredients are added, acrylic acid (ester) copolymer is selected as a suspension thickening agent, sodium lauryl polyether sulfate serving as a surfactant is selected, and the cocoyl amphodiacetate is matched, so that the transparency is extremely high, and the jelly is not produced at low temperature.
Preferably, the antibacterial moisturizing cosmetic is shower gel.
Preferably, the antibacterial moisturizing cosmetic further comprises the following components in parts by weight: 0.1-0.4 part of pH regulator, 0.1-0.4 part of preservative, 0.011-0.22 part of thickener, 0.01-0.12 part of adsorbent, 60-80 parts of solvent, 0.0001-0.1 part of colorant and 0.35-0.82 part of aromatic.
Preferably, the pH regulator is potassium hydroxide, the preservative is hydantoin, the thickener is corn starch and hydroxypropyl methyl cellulose, the adsorbent is microcrystalline cellulose, the solvent is water, the colorant is iron oxide yellow, and the aromatic is an essence.
Preferably, the weight ratio of the corn starch to the hydroxypropyl methyl cellulose in the thickener is corn starch: hydroxypropyl methylcellulose 0.01-0.12: 0.001-0.1.
Further preferably, the weight ratio of the corn starch to the hydroxypropyl methyl cellulose in the thickener is corn starch: hydroxypropyl methylcellulose 0.01: 0.001.
the body wash provided by the invention selects the coloring agent as iron oxide yellow, and the appearance visual effect of the particles is most beautiful; the aromatic is essence, and can be used for light and luxurious bath for 24 hr.
In addition, the invention also provides a preparation method of the antibacterial moisturizing cosmetic, which comprises the following steps:
(1) mixing water and sodium laureth sulfate, stirring and heating to obtain a mixed solution A after complete dissolution;
(2) cooling the mixed solution A to 75-80 ℃, defoaming, adding the mixed solution of pre-dispersed acrylic acid (ester) copolymer and water, stirring uniformly, adding the cocoyl amphodiacetate, and continuing to stir uniformly to obtain a mixed solution B;
(3) cooling the mixed solution B to 70-75 ℃, adding a mixed solution of potassium hydroxide and water, and uniformly stirring to obtain a mixed solution C;
(4) cooling the mixed solution C to 60-65 ℃, sequentially adding hydantoin, water, silver, soluble collagen and essence, and stirring until the mixed solution is colorless and transparent to obtain a mixed solution D;
(5) and adding corn starch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl methylcellulose and iron oxide yellow into the mixed solution D under stirring, and stirring uniformly to obtain the antibacterial moisturizing cosmetic.
Preferably, in the step (1), the frequency of stirring is 20-45HZ, and the temperature of heating is 85-95 ℃; in the step (2) and the step (3), the stirring frequency is 20-45 HZ; in the step (4) and the step (5), the stirring frequency is 10-45 HZ.
Preferably, in the step (3), the water added to the mixed solution B is cold water, potassium hydroxide and water undergo an exothermic reaction, and the cooled water is necessary to prevent the droplets from splashing.
Preferably, in the step (5), the prepared antibacterial moisturizing cosmetic needs to be color checked, and is discharged after being qualified without being filtered.
Compared with the prior art, the invention has the beneficial effects that:
(1) the provided suspensible moisturizing and bacteriostasis integrated shower gel has the advantages of high foaming speed, rich foam, less bubbles in the produced body and stable particle suspension.
(2) Provides special particles, wraps the fibroin, has bright color, not only preserves the activity of the effective components, but also slowly releases the active components to reduce the skin irritation, and has grain essence, and is interesting to the eyes.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
The antibacterial moisturizing cosmetic is shower gel in examples 1-5, and the components and parts by weight of the antibacterial moisturizing cosmetic are shown in table 1, the rest components are shown in table 2, and water is added to make up 100 parts
TABLE 1 selection of ingredients and parts by weight of bacteriostatic moisturizing cosmetic in examples 1-5
| Components | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 |
| Sodium laureth sulfate | 10 | 20 | 10.5 | 11 | 12 |
| Cocoiloyl amphodiacetic acid disodium salt | 2 | 8 | 6 | 3 | 6 |
| Acrylic acid (ester) copolymer | 2 | 2.2 | 2.1 | 2.1 | 2.1 |
| Soluble collagen | 0.01 | 0.1 | 0.1 | 0.08 | 0.06 |
| Silver (Ag) | 0.01 | 0.2 | 0.03 | 0.01 | 0.05 |
| Lactose | 0.01 | 0.1 | 0.03 | 0.02 | 0.04 |
| Sucrose | 0.01 | 0.1 | 0.03 | 0.02 | 0.04 |
Table 2 selection of remaining components and parts by weight of the bacteriostatic moisturizing cosmetic in examples 1-5
Examples 1-5 the preparation method of the shower gel described in the examples was as follows, after weighing the components in the parts by weight shown in tables 1 and 2:
(1) adding water into a main pot, homogenizing, adding sodium laureth sulfate, stirring, heating, and completely dissolving to obtain a mixed solution A;
(2) cooling the mixed solution A to 75-80 ℃, defoaming, adding the mixed solution of pre-dispersed acrylic acid (ester) copolymer and water, stirring uniformly, adding the cocoyl amphodiacetate, and continuing to stir uniformly to obtain a mixed solution B;
(3) cooling the mixed solution B to 70-75 ℃, adding a mixed solution of potassium hydroxide and water, and uniformly stirring to obtain a mixed solution C;
(4) cooling the mixed solution C to 60-65 ℃, sequentially adding hydantoin, water, silver, soluble collagen and essence, and stirring until the mixed solution is colorless and transparent to obtain a mixed solution D;
(5) and testing the pH value of the mixed solution D, stirring and adding corn starch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl methyl cellulose and iron oxide yellow after the mixed solution D is qualified, and uniformly stirring to obtain the bacteriostatic shower gel containing the suspended particles.
Test example 1 examples 1-5 moisturizing effect test
Procedure of the test
Randomly selecting 25 volunteers, randomly dividing into 5 groups, respectively correspondingly smearing the samples of examples 1-5 on 5 groups of 5 volunteers (male 1 and female 4), wetting the skin of the hand of the body, squeezing out a proper amount of bath to expose the bath on the hand, rubbing out foams, wiping the body, and finally washing the body with clear water; the moisture content of the skin before and after 1-4h of rinsing was measured using a Corneometer CM825 as a test instrument and averaged, and the test results are shown in the following table.
And (3) test results:
the moisturizing effect test is shown in Table 3
Table 3 examples 1-5 moisturizing performance test results
As can be seen from Table 3, examples 1-5 all have better moisturizing effects, wherein the moisturizing effect of example 3 is most obvious, and 4 hours after use, compared with before use, the moisture content of the skin after use is improved by 37.94%, which is greatly improved; 4 hours after the shower gel of the examples 4 and 5 is used, compared with the shower gel before use, the moisture content of the skin after use is respectively improved by 26.88 percent and 32.41 percent; the moisture content of the skin of the shower gel of the examples 1 and 2 after use is respectively improved by 20.55 percent and 18.57 percent compared with that of the skin before use after 4 hours after use. The shower gel provided by the embodiment of the invention has a good moisturizing effect.
Test example 2 examples 1 to 5 bacteriostatic effect test
Test object
Test strains: escherichia coli (ATCC 25922) (passage 4);
diluting liquid: phosphate buffered body fluid (PBS, 0.03mol/L, pH7.2;)
Culture medium: nutrient agar
Procedure of the test
The inspection basis is as follows: appendix C of GB15979-2002 hygienic Standard for Disposable sanitary articles
And (3) testing conditions: the test temperature was 20 ℃ and the test was repeated 3 times.
Test results
The results of the bacteriostatic effect test are shown in Table 4
TABLE 4 results of the Escherichia coli inhibition tests of examples 1 to 5
| Sequence number/scheme | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 |
| 1 | 90.66 | 92.56 | 99.99 | 95.34 | 93.21 |
| 2 | 74.50 | 92.43 | 99.98 | 95.33 | 93.20 |
| 3 | 74.52 | 92.38 | 99.97 | 95.32 | 93.22 |
| Average | 74.51 | 92.53 | 99.98 | 95.33 | 93.21 |
The bacteriostasis rate has 3 standards, one is more than 50 percent, and the bacteriostatic agent has bacteriostasis; one is more than 90 percent, and has stronger bacteriostatic action; one is more than 99.99 percent, has strong bacteriostatic action; as can be seen from Table 4, the shower gel prepared in the examples has a strong bacteriostatic effect on Escherichia coli (ATCC 25922) with an average bacteriostatic rate of more than 90% after the sample is applied for 2min under the test conditions.
Test example 3 examples 1-5 System stability testing
Procedure of the test
The particles and the material bodies of examples 1 to 5 were filled in 80g transparent bottles, and observed after 24 hours and 3 months
The stability test results are shown in Table 5
Table 5 examples 1-5 stability test results
| Scheme(s) | Example 1 | Example 2 | Example 3 | Example 4 | Example 5 |
| Viscosity (mPa.s) | 5900 | 5800 | 6200 | 6100 | 6000 |
| Stability (24 hours) | Is normal | Is normal | Is normal | Is normal | Is normal |
| Stability (3 months) | Particle normality | Particle normality | Particle normality | Particle normality | Particle normality |
| Transparency (10 points to full transparency) | 10 | 10 | 10 | 10 | 10 |
As can be seen from table 5, the shower gels prepared in examples 1 to 5 are all in a fully transparent state, and after 3 months, the ions still normally do not sink, indicating that the shower gel particles provided by the present invention are stable in suspension.
Meanwhile, comparative examples 1 to 7 are arranged in the application, the moisture retention components and the weight parts of the comparative examples 1 to 7 are selected as shown in Table 6, the rest components and the preparation method are completely the same as those of example 3, and the moisture retention effect test of the comparative examples 1 to 7 is shown in Table 7
Test example 4 test of moisturizing effect in comparative examples 1 to 7
Procedure of the test
Randomly selecting 35 volunteers, randomly dividing into 7 groups, respectively correspondingly smearing the samples of comparative examples 1-7 on 5 groups (male 1 and female 4) of volunteers in 7 groups, wetting the skin of the hand of the body, squeezing out a proper amount of bath to expose the bath on the hand, rubbing out foams, wiping the body, and finally washing the body with clear water; the moisture content of the skin before and after rinsing was measured using a Corneometer CM825 as a test instrument and averaged, and the test results are shown in Table 6 below.
TABLE 6 COMPARATIVE EXAMPLES 1-7 moisturizing Components and weight selection
TABLE 7 comparative examples 1 to 7 moisturizing Effect test
As shown by the results in tables 6 and 7, comparative examples 1 to 3 were 1 moisturizing component only, and the results in Table 7 showed that the moisturizing effect was not significant after use, and comparative examples 4 to 6 were two components, and showed that there was a certain moisturizing effect, but the moisturizing effect was still very different from that of the examples, and the moisture content of the skin was even decreased in the case of comparative example 7 containing no moisturizing component, and the results showed that there was a synergistic effect among the three moisturizing components, soluble collagen, lactose and sucrose.
Meanwhile, the present application sets comparative examples 8-13, the surfactant components and the parts by weight of comparative examples 8-11 are selected as shown in table 8, and the rest of the components and the preparation method are completely the same as those of example 3; the selection of the components and parts by weight of the suspension-thickening agent of comparative examples 12 to 13 are shown in Table 8, and the remaining components and the preparation method are exactly the same as those of example 3
TABLE 8 surfactant Components and part by weight selections for comparative examples 8-13
TABLE 7 results of physical and chemical tests of comparative examples 1 to 4
From the combination of tables 6 and 7, and comparative examples 8 to 11, it can be seen that the surfactant is selected from other commonly used surfactants on the market, which not only has low transparency and affects the appearance, but also has poor particle stability and sinks after a period of time; in comparative example 12, when the weight part of the acrylic acid (ester) copolymer was 1.8 parts, the particles were sunk; in comparative example 13, when the weight part of the acrylic copolymer was 2.4 parts, the jelly phenomenon occurred; therefore, the combined action of the acrylic acid (ester) copolymer in the suspension thickening agent, the sodium laureth sulfate in the surfactant and the disodium cocoyl amphodiacetate in the surfactant provides a system with stable particle suspension.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (8)
1. The antibacterial moisturizing cosmetic is characterized by comprising the following components in parts by weight: 12-28 parts of surfactant, 2-2.2 parts of suspension thickening agent, 0.01-0.2 part of skin conditioner and 0.03-0.3 part of humectant;
the suspension thickening agent is acrylic acid (ester) copolymer, the surfactant is sodium laureth sulfate and disodium cocoyl amphodiacetate, the skin conditioner is silver, and the humectant is soluble collagen, lactose and sucrose.
2. The bacteriostatic moisturizing cosmetic as claimed in claim 1, which is characterized by comprising the following components in parts by weight: 12-20 parts of surfactant, 2-2.2 parts of suspension thickening agent, 0.01-0.05 part of skin conditioner and 0.1-0.2 part of humectant;
the weight part of acrylic acid (ester) copolymer in the suspension thickener is 2-2.2 parts, and the weight ratio of sodium laureth sulfate to disodium cocoyl amphodiacetate in the surfactant is sodium laureth sulfate: 10-20 parts of cocoyl amphodiacetate disodium: 2-8; the weight part of the silver in the skin conditioner is 0.01-0.05 part; the humectant comprises the following components in parts by weight: sucrose ═ 0.01-0.1: 0.01-0.1: 0.01-0.1.
3. The bacteriostatic moisturizing cosmetic as claimed in claim 2, which is characterized by comprising the following components in parts by weight: 16.5 parts of surfactant, 2.1 parts of suspension thickening agent, 0.03 part of skin conditioner and 0.16 part of humectant;
the weight part of acrylic acid (ester) copolymer in the suspension thickener is 2.1 parts, and the weight ratio of sodium laureth sulfate to disodium cocoyl amphodiacetate in the surfactant is sodium laureth sulfate: cocoyl amphodiacetate disodium 10.5: 6; the skin conditioner comprises 0.03 part by weight of silver, and the humectant comprises soluble collagen, lactose and sucrose in a weight ratio of: lactose: sucrose ═ 0.1: 0.03: 0.03.
4. the bacteriostatic moisturizing cosmetic according to claim 1, wherein the bacteriostatic moisturizing cosmetic is a body wash.
5. The bacteriostatic moisturizing cosmetic as claimed in claim 4, further comprising the following components in parts by weight: 0.1-0.4 part of pH regulator, 0.1-0.4 part of preservative, 0.011-0.22 part of thickener, 0.01-0.12 part of adsorbent, 60-80 parts of solvent, 0.0001-0.1 part of colorant and 0.35-0.82 part of aromatic.
6. The bacteriostatic moisturizing cosmetic according to claim 5, wherein the pH regulator is potassium hydroxide, the preservative is hydantoin, the thickener is corn starch and hydroxypropyl methylcellulose, the adsorbent is microcrystalline cellulose, the solvent is water, the colorant is yellow iron oxide, and the fragrance is essence.
7. A method for preparing a bacteriostatic moisturizing cosmetic as claimed in claim 5 or 6, which comprises the following steps:
(1) mixing water and sodium laureth sulfate, stirring and heating to obtain a mixed solution A after complete dissolution;
(2) cooling the mixed solution A to 75-80 ℃, defoaming, adding the mixed solution of pre-dispersed acrylic acid (ester) copolymer and water, stirring uniformly, adding the cocoyl amphodiacetate, and continuing to stir uniformly to obtain a mixed solution B;
(3) cooling the mixed solution B to 70-75 ℃, adding a mixed solution of potassium hydroxide and water, and uniformly stirring to obtain a mixed solution C;
(4) cooling the mixed solution C to 60-65 ℃, sequentially adding hydantoin, water, silver, soluble collagen and essence, and stirring until the mixed solution is colorless and transparent to obtain a mixed solution D;
(5) and adding corn starch, microcrystalline cellulose, sucrose, lactose, hydroxypropyl methylcellulose and iron oxide yellow into the mixed solution D under stirring, and stirring uniformly to obtain the antibacterial moisturizing cosmetic.
8. The method for preparing a bacteriostatic moisture-retaining cosmetic as claimed in claim 7, wherein in the step (1), the frequency of stirring is 20 to 45HZ, and the temperature of heating is 85 to 95 ℃; in the step (2) and the step (3), the stirring frequency is 20-45 HZ; in the step (4) and the step (5), the stirring frequency is 10-45 HZ.
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