CN112106892A - Sow feed additive and preparation method and application thereof - Google Patents
Sow feed additive and preparation method and application thereof Download PDFInfo
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- CN112106892A CN112106892A CN202010974809.XA CN202010974809A CN112106892A CN 112106892 A CN112106892 A CN 112106892A CN 202010974809 A CN202010974809 A CN 202010974809A CN 112106892 A CN112106892 A CN 112106892A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
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Abstract
The invention relates to the technical field of feed additives, in particular to a sow feed additive and a preparation method thereof. The raw materials of the sow feed additive comprise fresh enteromorpha, fresh fig leaves and montmorillonite powder, the fresh enteromorpha and the fresh fig leaves are taken, crushed and uniformly mixed, protease in the fig leaves is utilized for full enzymolysis, then the montmorillonite powder is added and uniformly stirred, and the feed additive is obtained after high-pressure spray drying. The sow feed additive prepared by the invention basically has no influence on the weight of piglets, but can obviously improve the survival rate of the piglets and reduce the diarrhea rate of the piglets. By matching fresh enteromorpha prolifera and fig leaves, the protease of the fig leaves is skillfully utilized, and the active ingredients in the enteromorpha prolifera are fully released, so that the aims of resisting virus and germs, improving the immunity of sows and improving the survival rate of piglets are fulfilled.
Description
Technical Field
The invention relates to the technical field of feed additives, in particular to a sow feed additive and a preparation method and application thereof.
Background
The information in this background section is only for enhancement of understanding of the general background of the invention and is not necessarily to be construed as an admission or any form of suggestion that this information forms the prior art that is already known to a person of ordinary skill in the art.
The pig industry is an important component of the animal husbandry in China, and with the continuous development of the pig industry, the survival rate and the quality of piglets become important components influencing the pig industry. In addition, higher requirements are put forward for safety evaluation standards of veterinary drug residues and feed additives in the livestock industry at present. In recent years, along with the prohibition and limitation of antibiotics, China develops endless researches and applications on antibiotic substitutes and antibiotic breeding. But the sow feed additive aiming at improving the survival rate of piglets is less specially developed. Viruses and bacteria are important factors influencing the survival rate of piglets, but at present, better medicines for resisting viral diseases are lacked, and antibiotics which are only effective to bacteria are used only, so that the antiviral diseases cannot be effectively treated.
The enteromorpha belongs to large-scale seaweed with wide temperature, wide salt and strong desiccation resistance, the eutrophication degree of the seawater is continuously improved due to the influence of human activities, and the enteromorpha is difficult to completely disappear in a short time due to the influence of climate change effect, and if the enteromorpha is not fished and utilized in time, the natural landscape of the seashore is influenced and the environment is polluted. Therefore, how to effectively utilize enteromorpha resources becomes an important topic for improving ecological environment and comprehensively utilizing seaweed.
The folium fici is leaf of Ficus carica L. of Ficus of Moraceae. At present, fig is planted in a large amount in the Weihai region, but the leaves of the fig are not developed and utilized basically. The fig leaves contain various nutritional ingredients such as malic acid, citric acid, lipase, protease, hydrolase and the like, and if the fig leaves can be fully utilized, waste materials can be changed into valuable materials, and a larger economic value is created.
Disclosure of Invention
As discussed in the background, with the banning and restriction of antibiotics, the research and application of antibiotic substitutes becomes more and more important, and few in the prior art are specially developed sow feed additives aiming at improving the survival rate of piglets. And the virus and the bacteria are important factors influencing the survival rate of the piglets, and the sow feed additive provided by the invention can simultaneously obtain good antibacterial and antiviral effects, so that the survival rate of the piglets is improved.
In order to solve the technical problems in the prior art, the technical scheme of the invention is as follows:
in a first aspect of the present invention, there is provided a sow feed additive, the raw materials of which comprise fresh enteromorpha, fresh fig leaves and montmorillonite powder.
Preferably, the mass ratio of the fresh enteromorpha, the fresh fig leaves and the montmorillonite powder is as follows: 3-5 kg: 0.5-2 kg: 0.3-1 kg.
In a second aspect of the invention, a preparation method of the sow feed additive in the first aspect is provided, wherein fresh enteromorpha prolifera and fresh fig leaves are crushed and then uniformly mixed, protease in the fig leaves is utilized for full enzymolysis, montmorillonite powder is added and uniformly stirred, and the feed additive is obtained through high-pressure spray drying.
Preferably, the conditions of the enzymolysis are as follows: the enzymolysis conditions are as follows: stirring at 40-50 deg.C for 1-2h for enzymolysis;
more preferably: stirring for 2h at 45 ℃ for full enzymolysis;
preferably, the montmorillonite powder is added and stirred for 0.5 h.
In a third aspect of the invention, there is provided the use of a sow feed additive as described in the first aspect, for increasing the survival rate of piglets.
In a fourth aspect of the invention, there is provided a sow feed comprising the sow feed additive of the first aspect.
The specific embodiment of the invention has the following beneficial effects:
1. fresh enteromorpha and fig leaves are adopted, so that the effective active ingredients in the enteromorpha and fig leaves can be retained to the maximum extent.
2. The fresh enteromorpha is degraded by adopting the protease in the fig leaves, the degradation efficiency is high, and the cost is low.
3. After degradation by ficin, enteromorpha polysaccharide in enteromorpha can be released repeatedly, so that the antiviral capacity of enteromorpha polysaccharide can be better delivered.
4. The antimicrobial components of the fig leaves may also be retained in the feed additive.
5. Ficin can improve the utilization rate of pig feed.
6. The addition of the montmorillonite powder can not only improve the efficiency of spray drying, but also effectively protect active ingredients in enteromorpha and fig leaves.
7. By matching fresh enteromorpha prolifera and fig leaves, the protease of the fig leaves is skillfully utilized, and the active ingredients in the enteromorpha prolifera are fully released, so that the aims of resisting virus and germs, improving the immunity of sows and improving the survival rate of piglets are fulfilled.
8. The development and utilization of the enteromorpha and the fig leaves belong to changing waste into valuable and are beneficial to environmental protection.
Detailed Description
The invention will be further illustrated with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. The experimental procedures, in which specific conditions are not noted in the following examples, are generally carried out according to conventional conditions or according to conditions recommended by the manufacturers.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. The reagents or starting materials used in the present invention can be purchased from conventional sources, and unless otherwise specified, the reagents or starting materials used in the present invention can be used in a conventional manner in the art or in accordance with the product specifications. In addition, any methods and materials similar or equivalent to those described herein can be used in the methods of the present invention. The preferred embodiments and materials described herein are intended to be exemplary only.
In order to obtain the feed additive which can replace antibiotics and has antibacterial and antiviral effects and improve the survival rate of piglets, the invention provides the sow feed additive and the preparation method and the application thereof.
In one embodiment of the invention, the sow feed additive is provided, and raw materials of the sow feed additive comprise fresh enteromorpha, fresh fig leaves and montmorillonite powder.
Fresh enteromorpha and fig leaves are adopted, so that effective active ingredients in the fresh enteromorpha and the fig leaves can be retained to the maximum extent, and antibacterial ingredients in the fig leaves can also be retained in the feed additive; the addition of montmorillonite powder can effectively protect active ingredients in enteromorpha and fig leaves. And the development and utilization of the enteromorpha prolifera and the fig leaves belong to changing waste into valuable, and are beneficial to environmental protection.
In a preferred embodiment, the mass ratio of the fresh enteromorpha, the fresh fig leaves and the montmorillonite powder is as follows: 3-5 kg: 0.5-2 kg: 0.3-1 kg.
In an embodiment of the invention, a preparation method of the sow feed additive is provided, wherein fresh enteromorpha prolifera and fresh fig leaves are crushed and then uniformly mixed, protease in the fig leaves is utilized for full enzymolysis, montmorillonite powder is added and uniformly stirred, and the feed additive is obtained through high-pressure spray drying.
In a preferred embodiment, the conditions of the enzymatic hydrolysis are: stirring at 40-50 deg.C for 1-2h for enzymolysis;
the temperature condition is favorable for the protease in the fig leaves to exert activity, and can keep the effective components in the enteromorpha and the fig leaves from being degraded by high temperature.
In a preferred embodiment, the montmorillonite powder is added and stirred for 0.5 h.
The fresh enteromorpha is degraded by adopting the protease in the fig leaves, so that the degradation efficiency is high and the cost is low; after degradation by ficin, enteromorpha polysaccharide in enteromorpha can be released repeatedly, so that the antiviral capacity of enteromorpha polysaccharide is better delivered; ficin can improve the utilization rate of pig feed. The addition of montmorillonite powder can also improve the efficiency of spray drying;
by matching fresh enteromorpha prolifera and fig leaves, the protease of the fig leaves is skillfully utilized, and the active ingredients in the enteromorpha prolifera are fully released, so that the aims of resisting virus and germs, improving the immunity of sows and improving the survival rate of piglets are fulfilled.
In one embodiment of the invention, the application of the sow feed additive in improving the survival rate of piglets is provided.
In one embodiment of the invention, a sow feed is provided, which comprises the above sow feed additive.
The invention is further illustrated by the following examples, which are not to be construed as limiting the invention thereto. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention.
Example 1
Taking 5kg of fresh enteromorpha prolifera and 1kg of fresh fig leaves, crushing, uniformly mixing, stirring for 2h at 45 ℃, fully performing enzymolysis, then adding 0.5kg of montmorillonite powder, stirring for 0.5h, and finally performing high-pressure spray drying to obtain the feed additive.
Example 2
Taking 4kg of fresh enteromorpha prolifera and 1kg of fresh fig leaves, crushing, uniformly mixing, stirring for 1.5h at 40 ℃, fully performing enzymolysis, then adding 0.4kg of montmorillonite powder, stirring for 0.5h, and finally performing high-pressure spray drying to obtain the feed additive.
Example 3
Taking 3kg of fresh enteromorpha prolifera and 1kg of fresh fig leaves, crushing, uniformly mixing, stirring for 1h at 50 ℃ for sufficient enzymolysis, then adding 0.3kg of montmorillonite powder, stirring for 0.5h, and finally performing high-pressure spray drying to obtain the feed additive.
Research on virus infection prevention activity of the feed additive:
the feed additive prepared in example 1 was used for the test.
Mice were randomly divided into 4 groups by weight, which were a normal control group, a 0.5% dose group, a 1% dose group, and a 2% dose group, 10 mice per group. The normal control group is fed with normal feed, and the feed additive prepared by adding the feed additive into the feed according to the corresponding proportion in percentage by mass is respectively fed into the 0.5 percent dosage group, the 1 percent dosage group and the 2 percent dosage group. After one month of feeding, all mice were exposed to H1N1 influenza A virus in air for 15 min. On day 5 post-infection, the number of infected animals was counted.
TABLE 1 feed additive Activity for prevention of viral infections results
From the above table, it can be seen that the amount of virus infection of mice can be significantly reduced after the feed additive is added, and the dosage is dependent. Better effect can be achieved by adding 1% of the feed into normal feed.
Research on bacterial infection prevention activity of the feed additive:
mice were randomly divided into 4 groups by weight, which were a normal control group, a 0.5% dose group, a 1% dose group, and a 2% dose group, 10 mice per group. The normal control group is fed with normal feed, and the feed additive prepared by adding the feed additive into the feed according to the corresponding proportion in percentage by mass is respectively fed into the 0.5 percent dosage group, the 1 percent dosage group and the 2 percent dosage group. After one month of feeding, each mouse was gavaged to a concentration of about 10X 109Staphylococcus aureus (in saline) at 0.5 mL/mL. On day 5 post-infection, the number of infected dead animals was counted.
TABLE 2 feed additive Activity for preventing bacterial infections results
From the above table, it can be seen that the amount of virus infection of mice can be significantly reduced after the feed additive is added, and the dosage is dependent. Better effect can be achieved by adding 1% of the feed into normal feed.
Research on survival rate of piglets improved by the feed additive:
a total of 25 pregnant sows for the second farrowing are selected, randomly divided into 5 groups, including: the feed additive comprises a normal group (fed with normal feed), an enteromorpha group (1 mass percent of enteromorpha dry powder is added into the normal feed), a fig leaf group (1 mass percent of fig dry powder is added into the normal feed), a dry powder group (1 mass percent of premixed dry powder is added into the normal feed, the ratio of enteromorpha powder to fig dry powder to montmorillonite powder in the premixed dry powder is 10:3:10), and a feed additive group (1 mass percent of feed additive prepared by the method is added into the normal feed). The pregnant sows are fed with corresponding feeds according to groups from the first time before delivery and are fed to piglets weaned 25 days after delivery. And (5) counting the weight, survival rate, diarrhea rate and the like of the piglets.
TABLE 3 study of feed additives to improve survival rate of piglets
The results show that the feed additive prepared by the invention basically has no influence on the weight of piglets, but can obviously improve the survival rate of the piglets and reduce the diarrhea rate of the piglets.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. A feed additive for sow comprises fresh Enteromorpha prolifera, fresh folium fici and montmorillonite powder.
2. The sow feed additive as claimed in claim 1, wherein the fresh enteromorpha, fresh fig leaves and montmorillonite powder are in a mass ratio of: 3-5 kg: 0.5-2 kg: 0.3-1 kg.
3. The preparation method of the sow feed additive as described in claim 1, which is characterized in that the preparation method comprises the following steps: taking fresh enteromorpha prolifera and fresh fig leaves, crushing, mixing uniformly, performing full enzymolysis by using protease in the fig leaves, adding montmorillonite powder, stirring uniformly, and performing high-pressure spray drying to obtain the feed additive.
4. The method for preparing a feed additive for sows as claimed in claim 3, wherein the conditions of the enzymatic hydrolysis are: stirring at 40-50 deg.C for 1-2h for enzymolysis.
5. The method of producing the feed additive for sows as set forth in claim 4, wherein the enzymatic hydrolysis temperature is 45 ℃; the enzymolysis time is 2 h.
6. The method for producing a feed additive for sows as claimed in claim 3, wherein the montmorillonite powder is added thereto and stirred for 0.5 hour.
7. Use of the sow feed additive of claim 1 or 2 for increasing survival rate of piglets.
8. A sow feed comprising the sow feed additive of claim 1 or 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010974809.XA CN112106892A (en) | 2020-09-16 | 2020-09-16 | Sow feed additive and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010974809.XA CN112106892A (en) | 2020-09-16 | 2020-09-16 | Sow feed additive and preparation method and application thereof |
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| Publication Number | Publication Date |
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| CN112106892A true CN112106892A (en) | 2020-12-22 |
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| CN202010974809.XA Pending CN112106892A (en) | 2020-09-16 | 2020-09-16 | Sow feed additive and preparation method and application thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406056A (en) * | 2011-10-13 | 2012-04-11 | 东莞市银华生物科技有限公司 | Soybean meal fermented by pineapple juice, preparation method and application thereof |
| CN103478427A (en) * | 2013-09-30 | 2014-01-01 | 中国海洋大学生物工程开发有限公司 | Enteromorpha polysaccharide feed additive as well as preparation method and application thereof |
| CN107744070A (en) * | 2017-09-28 | 2018-03-02 | 临汾市碧丰霖农业科技开发有限公司 | A kind of fig home poultry raising liquid |
| CN108354062A (en) * | 2017-12-23 | 2018-08-03 | 青岛麦迪尔生物工程有限公司 | A kind of enteromorpha oligosaccharide poultry and livestock feed additive |
-
2020
- 2020-09-16 CN CN202010974809.XA patent/CN112106892A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406056A (en) * | 2011-10-13 | 2012-04-11 | 东莞市银华生物科技有限公司 | Soybean meal fermented by pineapple juice, preparation method and application thereof |
| CN103478427A (en) * | 2013-09-30 | 2014-01-01 | 中国海洋大学生物工程开发有限公司 | Enteromorpha polysaccharide feed additive as well as preparation method and application thereof |
| CN107744070A (en) * | 2017-09-28 | 2018-03-02 | 临汾市碧丰霖农业科技开发有限公司 | A kind of fig home poultry raising liquid |
| CN108354062A (en) * | 2017-12-23 | 2018-08-03 | 青岛麦迪尔生物工程有限公司 | A kind of enteromorpha oligosaccharide poultry and livestock feed additive |
Non-Patent Citations (1)
| Title |
|---|
| 乔洪明: "《无花果 人类健康的守护神》", 31 August 2011, 山东大学出版社 * |
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