CN1120943A - Nose opening capsule and its preparation method - Google Patents
Nose opening capsule and its preparation method Download PDFInfo
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- CN1120943A CN1120943A CN 94116800 CN94116800A CN1120943A CN 1120943 A CN1120943 A CN 1120943A CN 94116800 CN94116800 CN 94116800 CN 94116800 A CN94116800 A CN 94116800A CN 1120943 A CN1120943 A CN 1120943A
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- herba
- radix
- nose opening
- levigation
- opening capsule
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Abstract
The nose opening capsule is compounded with 12 kinds of Chinese medicinal material including Magnolia lififlora, Dahurian angelica root, Saposhnikovia divaricata, Astragalus membranaceus, schisandra, etc. via the processes of decoction to obtain extract, grinding and sieving, stoving, and encapsulation. Clinical use shows that it has high curative effect on various nose diseases and esp on nasopharynx cancer.
Description
The present invention relates to a kind of nose opening capsule of specially controlling all kinds of cacorhinias and preparation method thereof, belong to Chinese medicine manufacturing technology field.
At present, operation, puncture, the heavy dose of antibiotic therapy method of injection are mainly adopted in clinical treatment to cacorhinia both at home and abroad, and the patient suffering is big, expense is high, the course of treatment is long, curative effect is low, and recurrence rate after healing is higher.
Immediate with the present invention in the prior art is disclosed application number 93100941.3 publication number CN1090763A Augusts 17 in 1994, name is called the application for a patent for invention of " medicine " Xincangbiyuan powder " for treating rhinitis ", this medicine is by Fructus Xanthii, Flos Magnoliae, Herba Centipedae, the Radix Angelicae Dahuricae, Herba Asari, dried Alumen, catechu, Indigo Naturalis, Pedicellus Melo, Radix Kansui, Asteriscus Pseudosciaenae ten Chinese medicine simply constitutes, this medicine composition is at the rhinitis disease and compatibility, though the rhinitis disease is had certain curative effect, but to epistaxis, other various cacorhinias such as nasal polyp are powerless, even certain effect is arranged, its curative effect is very little, let alone cure, do not recur after healing etc.
The object of the present invention is to provide a kind of Chinese medicine nose opening capsule for the treatment of all kinds of cacorhinias and preparation method thereof, pure Chinese medicinal ingredients has no side effect, and taking convenience, no pain, expense is low, short treating period, curative effect height, recurrence rate after healing is low, and it is wide to adapt to cacorhinia disease scope, to all kinds of acute and chronic rhinitis, various cacorhinias such as acute and chronic allergic rhinitis, epistaxis, nasal polyp all have satisfied curative effect, particularly preferable to the nasopharyngeal carcinoma curative effect, this medicament preparation simple possible, the effective components of Chinese medicinal utilization is abundant.
Design philosophy of the present invention and treatment are theoretical: the traditional Chinese medical science thinks that nose helps and swallows for door, department's olfactory sensation of breathing, under lung system, if ailment said due to cold or exposure is violated lung, lung meridian has heat, symptoms such as watery nasal discharge, nasal obstruction, epistaxis then occur, intimately go up inflammation, easily cause the nose massive hemorrhage or give birth to nose treatment etc. such as the Yangming Channel arteries and veins, the Gallbladder Channel of Foot-Shaoyang has heat, easily cause nasal sinusitis, dizzy headache etc., spleen kidney deficiency, easily cause diseases such as epistaxis, nasal mucus.The present invention is by Flos Magnoliae, the Radix Angelicae Dahuricae, Zhu Tongcao, Radix Saposhnikoviae, Radix Astragali, Fructus Schisandrae Chinensis, Fructus Xanthii, Squama Manis, Herba Hedyotidis Diffusae, Radix Platycodonis, Herba Patriniae, Herba Ephedrae 12 flavor Chinese medicines are formed, wherein Flos Magnoliae has the sensible effect of diffusing wind, the Radix Angelicae Dahuricae has the lung qi dispersing of dispeling the wind effect, Fructus Xanthii has a surname's clearing the nasal passage, the wind analgesic effect looses, Zhu Tongcao has the effect of mediation nose gas, Radix Saposhnikoviae has the inducing diaphoresis to dispel wind analgesic effect, Fructus Schisandrae Chinensis has astringes the lung, YIN nourishing, promote the production of body fluid and end the tears effect, Squama Manis has the secondary stain carbuncle that disappears, search the active effect of wind, Radix Astragali has benefit and defends consolidating superficial resistance, the promoting pus discharge and tissue regeneration strengthening effect, Herba Hedyotidis Diffusae has clearing away heat-damp and promoting diuresis, the effect of detoxifcation dissipating blood stasis, Radix Platycodonis has out lung qi dispersing gas, the evacuation of pus effect of eliminating the phlegm, Herba Patriniae has heat-clearing and toxic substances removing, the effect of evacuation of pus removing blood stasis with potent drugs, Herba Ephedrae has the diaphoresis diuretic, clear nose blocking action.And Flos Magnoliae, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Radix Platycodonis compatibility are can lung qi dispersing sensible, the plug cephalocathartic disappears, with Fructus Xanthii, Zhu Tongcao, Herba Ephedrae compatibility energy wind-expelling pain-stopping, again with Squama Manis, Herba Hedyotidis Diffusae, Herba Patriniae compatibility energy heat-clearing and toxic substances removing, row's necrotic tissue and promoting muscle growing, and Squama Manis have draw all medicines go into through effect, have benefit with Fructus Schisandrae Chinensis, Radix Astragali compatibility again and defend the only effect of tears, QI invigorating the kidney invigorating of consolidating superficial resistance, convergence, promptly reach the purpose of treatment cacorhinia.
Formulation content of the present invention is (a unit: g): Flos Magnoliae 9-16, the Radix Angelicae Dahuricae 9-20, Zhu Tongcao 9-20, Radix Saposhnikoviae 6-12, Radix Astragali 6-15, Fructus Schisandrae Chinensis 6-15, Fructus Xanthii 6-15, Squama Manis 3-9, Herba Hedyotidis Diffusae 6-20, Radix Platycodonis 3-9, Herba Patriniae 6-20, Herba Ephedrae 3-9, and above-mentioned formulation content is amplified according to production lot size equal proportion or is dwindled.
In addition, the available property of medicine and Flos Magnoliae are close, act on essentially identical Herba Houttuyniae 18-32g or Herba Centipedae 18-32g or Herba Andrographis 18-32g and replace Flos Magnoliae 9-16g; Close with the property of medicine and Herba Patriniae, act on basic identical Spina Gleditsiae 12-40g or Flos Lonicerae 12-40g or Herba Taraxaci 12-40g and replace Herba Patriniae 6-20g; Close with the property of medicine and the Radix Angelicae Dahuricae, act on basic identical Rhizoma Et Radix Notopterygii 9-20g or Ramulus Cinnamomi 6-18g or Flos Chrysanthemi 18-40g and replace the Radix Angelicae Dahuricae 9-20g; Also can add the antiseptic of its gross weight 1% and 1% Mentholum in described formulation content, antiseptic selects for use boric acid to get final product.
Preparation method of the present invention: earlier with Herba Ephedrae, Herba Hedyotidis Diffusae, the Radix Angelicae Dahuricae, Fructus Xanthii, Herba Patriniae, Flos Magnoliae mixes the water that the back adds 2 times of its doses by described content, be that the liquid medicine weight ratio is 1: 2, under 60 ℃ of-80 ℃ of temperature, make extractum by the Chinese medicine boiling method, because this 6 flavor medicine active ingredient is easy to become solution in water but all can volatilizees its active ingredient in the time of 100 ℃, so must remain under 60 ℃ of-80 ℃ of range temperature and be brewed into extractum to make full use of its active ingredient, guaranteeing that curative effect simultaneously, reduce and take dose, with Squama Manis, Radix Saposhnikoviae mixes the back by described content and processs yellow back levigation with traditional method, Radix Astragali can be gone into the lung QI invigorating, can be by the direct levigation of described content, Radix Platycodonis dries the back levigation by described content, with the Fructus Schisandrae Chinensis processed with wine, be that the Steam by water bath of packing into 1: 5 ratio is mixed Fructus Schisandrae Chinensis thoroughly with yellow wine after in the container is treated to dry levigation after wine blots promptly in yellow wine and Fructus Schisandrae Chinensis weight ratio, Zhu Tongcao prepares directly levigation of back by Medulla Tetrapanacis and Cinnabaris by 10: 1 weight ratios, the extractum of crossing sieves on the 100-120th after the medicated powder mixing that above-mentioned development is good and being brewed into is mixed thoroughly to dry under 40 ℃ of-60 ℃ of temperature and promptly be can be made into the finished medicines powder, finished product medicated powder is incapsulated promptly can be made into the present invention.Also can add described 12 flavor Chinese medicine gross weight 1% antiseptic and 1% Mentholums in the finished product medicated powder of making mixes thoroughly to incapsulate after waiting to do and makes the present invention.
The present invention is compared with prior art: taking convenience, no pain, expense is low, and short treating period, curative effect height do not recur after healing, it is wide to adapt to cacorhinia disease scope, all kinds of cacorhinias all there is reasonable curative effect, particularly preferable to the nasopharyngeal carcinoma curative effect, through clinical use effective percentage 100% cure rate of 3500 routine patients more than 95%, take this medicine and take effect that accounting for took effect in 74%, one week accounts for 21% in three days.In addition, oral this medicine 20 routine patients with the 20 routine patients' contrasts of antibiotic therapy matched group, oral this medicine sx 17 examples after three days, and 6 examples are only arranged with what antibiotic was treated sx after three days.And preparation method science of the present invention, simple, the effective components of Chinese medicinal utilization is abundant, has increased curative effect of the present invention to a certain extent.
(unit: g), its preparation method is identical with description the 5th part preparation method, and formulation content by specification the 5th part preparation method by embodiment 1,2,3 promptly can be made into embodiment 1,2,3 respectively for the embodiment of the invention 1,2,3.As if " 0 " number capsule that the medicated powder of making is packed into, every capsules filling dose is 0.5g, then each oral three 1.5g, and every day three times, 2-4 week is a course of treatment.
Embodiment 1 embodiment 2 embodiment 3
Flos Magnoliae 10 13 15
The Radix Angelicae Dahuricae 10 15 19
Zhu Tongcao 10 15 19
Radix Saposhnikoviae 79 11
Radix Astragali 79 14
Fructus Schisandrae Chinensis 79 14
Fructus Xanthii 79 14
Squama Manis 468
Herba Hedyotidis Diffusae 79 18
Radix Platycodonis 468
Herba Patriniae 79 18
Herba Ephedrae 348
Embodiment 4 (unit: g): Herba Houttuyniae 30g, Rhizoma Et Radix Notopterygii 15, Zhu Tongcao 14, Radix Saposhnikoviae 8, Radix Astragali 8, Fructus Schisandrae Chinensis 8, Fructus Xanthii 8, Squama Manis 5, Herba Hedyotidis Diffusae 8, Radix Platycodonis 5, Spina Gleditsiae 30, Herba Ephedrae 4.
Its preparation method is identical with description the 5th part preparation method, and using method is identical with embodiment 1,2,3.
Embodiment 5 (unit: g): Herba Centipedae 30, Ramulus Cinnamomi 12, Zhu Tongcao 16, Radix Saposhnikoviae 10, Radix Astragali 10, Fructus Schisandrae Chinensis 10, Fructus Xanthii 10, Squama Manis 7, Herba Hedyotidis Diffusae 10, Radix Platycodonis 7, Flos Lonicerae 30, Herba Ephedrae 5.
Its preparation method is identical with description the 5th part preparation method, and using method is identical with embodiment 1,2,3.
Embodiment 6 (unit: g): Herba Andrographis 30, Flos Chrysanthemi 30, Zhu Tongcao 15, Radix Saposhnikoviae 9, Radix Astragali 9, Fructus Schisandrae Chinensis 9, Fructus Xanthii 9, Squama Manis 6, Herba Hedyotidis Diffusae 9, Radix Platycodonis 6, Herba Taraxaci 30, Herba Ephedrae 3, boric acid 1.65, Mentholum 1.65.
Its preparation method is identical with description the 5th part preparation method, and using method is identical with embodiment 1,2,3.
Claims (6)
1, a kind of nose opening capsule is characterized in that: the formulation content of this medicine is (a unit: g): Flos Magnoliae 9-16, the Radix Angelicae Dahuricae 9-20, Zhu Tongcao 9-20, Radix Saposhnikoviae 6-12, Radix Astragali 6-15, Fructus Schisandrae Chinensis 6-15, Fructus Xanthii 6-15, Squama Manis 3-9, Herba Hedyotidis Diffusae 6-20, Radix Platycodonis 3-9, Herba Patriniae 6-20, Herba Ephedrae 3-9, and above-mentioned formulation content is amplified according to production lot size equal proportion or is dwindled.
2, nose opening capsule according to claim 1 is characterized in that: with Herba Houttuyniae 18-32g or Herba Centipedae 18-32g or Herba Andrographis 18-32g replacement Flos Magnoliae 9-16g.
3, nose opening capsule according to claim 1 is characterized in that: with Spina Gleditsiae 12-40g or Flos Lonicerae 12-40g or Herba Taraxaci 12-40g replacement Herba Patriniae 6-20g.
4, nose opening capsule according to claim 1 is characterized in that: with Rhizoma Et Radix Notopterygii 9-20g or Ramulus Cinnamomi 6-18g or Flos Chrysanthemi 18-40g replacement Radix Angelicae Dahuricae 9-20g.
5, nose opening capsule according to claim 1 is characterized in that: also can add the antiseptic of its gross weight 1% and 1% Mentholum in the described formulation content.
6, the preparation method of the described nose opening capsule of a kind of claim 1, it is characterized in that: earlier Herba Ephedrae, Herba Hedyotidis Diffusae, the Radix Angelicae Dahuricae, Fructus Xanthii, Herba Patriniae, Flos Magnoliae are mixed the water that the back adds 2 times of its doses by described content, be that the liquid medicine weight ratio is 1: 2, under 60 ℃ of-80 ℃ of temperature, make extractum by the Chinese medicine boiling method; With Squama Manis, Radix Saposhnikoviae mixes the back by described content and processs yellow back levigation with traditional method, Radix Astragali is pressed the direct levigation of described content, Radix Platycodonis dries the back levigation by described content, with the Fructus Schisandrae Chinensis processed with wine, be that the Steam by water bath of packing into 1: 5 ratio is mixed Fructus Schisandrae Chinensis thoroughly with yellow wine after in the container is treated to dry levigation after wine blots promptly in yellow wine and Fructus Schisandrae Chinensis weight ratio, Zhu Tongcao prepares directly levigation of back by Medulla Tetrapanacis and Cinnabaris by 10: 1 weight ratios, the extractum of crossing 100-120 mesh sieves after the medicated powder that above-mentioned development is good mixes and being brewed into is mixed thoroughly to dry under 40 ℃ of-60 ℃ of temperature and promptly be can be made into the finished medicines powder, finished product medicated powder is incapsulated promptly can be made into the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94116800 CN1120943A (en) | 1994-10-21 | 1994-10-21 | Nose opening capsule and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94116800 CN1120943A (en) | 1994-10-21 | 1994-10-21 | Nose opening capsule and its preparation method |
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| Publication Number | Publication Date |
|---|---|
| CN1120943A true CN1120943A (en) | 1996-04-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 94116800 Pending CN1120943A (en) | 1994-10-21 | 1994-10-21 | Nose opening capsule and its preparation method |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099886C (en) * | 1999-03-19 | 2003-01-29 | 广东医学院 | Biaining as one medicine for nasopharyngeal cancer |
| CN102727675A (en) * | 2012-06-20 | 2012-10-17 | 葛文农 | Traditional Chinese medicine capsules used for treating nasal sinusitis |
| CN103055155A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating nasopharyngeal carcinoma and preparation method thereof |
| CN103110774A (en) * | 2013-01-31 | 2013-05-22 | 李浩成 | Chinese herbal preparation for treating epistaxis and preparation method thereof |
| CN103169784A (en) * | 2013-03-02 | 2013-06-26 | 赵明叶 | Traditional Chinese medicine for treating rhinitis |
| CN104398964A (en) * | 2014-12-01 | 2015-03-11 | 郭文喜 | Traditional Chinese medicinal composition for treating allergic rhinitis |
| CN104922279A (en) * | 2015-06-30 | 2015-09-23 | 赵德欣 | External use traditional Chinese medicine composition for treating chronic rhinitis and preparing method of external use traditional Chinese medicine composition |
| CN106237299A (en) * | 2016-08-31 | 2016-12-21 | 安徽省润生医药股份有限公司 | The treatment pharmaceutical composition of allergic rhinitis, its preparation method and preparation |
-
1994
- 1994-10-21 CN CN 94116800 patent/CN1120943A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1099886C (en) * | 1999-03-19 | 2003-01-29 | 广东医学院 | Biaining as one medicine for nasopharyngeal cancer |
| CN102727675A (en) * | 2012-06-20 | 2012-10-17 | 葛文农 | Traditional Chinese medicine capsules used for treating nasal sinusitis |
| CN103055155A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating nasopharyngeal carcinoma and preparation method thereof |
| CN103110774A (en) * | 2013-01-31 | 2013-05-22 | 李浩成 | Chinese herbal preparation for treating epistaxis and preparation method thereof |
| CN103110774B (en) * | 2013-01-31 | 2014-06-18 | 郑立学 | Chinese herbal preparation for treating epistaxis and preparation method thereof |
| CN103169784A (en) * | 2013-03-02 | 2013-06-26 | 赵明叶 | Traditional Chinese medicine for treating rhinitis |
| CN104398964A (en) * | 2014-12-01 | 2015-03-11 | 郭文喜 | Traditional Chinese medicinal composition for treating allergic rhinitis |
| CN104922279A (en) * | 2015-06-30 | 2015-09-23 | 赵德欣 | External use traditional Chinese medicine composition for treating chronic rhinitis and preparing method of external use traditional Chinese medicine composition |
| CN106237299A (en) * | 2016-08-31 | 2016-12-21 | 安徽省润生医药股份有限公司 | The treatment pharmaceutical composition of allergic rhinitis, its preparation method and preparation |
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