CN1589839A - Stasis transforming pain relieving particle agent and its preparation method - Google Patents
Stasis transforming pain relieving particle agent and its preparation method Download PDFInfo
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- CN1589839A CN1589839A CN 03144224 CN03144224A CN1589839A CN 1589839 A CN1589839 A CN 1589839A CN 03144224 CN03144224 CN 03144224 CN 03144224 A CN03144224 A CN 03144224A CN 1589839 A CN1589839 A CN 1589839A
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- radix
- rhizoma
- moschus
- rehmanniae preparata
- carapax trionycis
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Abstract
An antalgic Chinese medicine in the form of particles for treating the pain caused by cancer is prepared from 28 Chinese-medicinal materials including motherwort, ginseng, astragalus root, safflower, etc. Its preparing process is also disclosed.
Description
Technical field
The invention belongs to field of pharmaceutical preparations; Specifically belong to field of traditional Chinese.
Background technology
Cancer pain is that cancer brings one of the most painful symptom of patient; Its pain is violent, and making medical circles is that it has concluded three ladder principle of medication-from prevailing antipyretic analgesic aspirin specially to five-star potent opium kind analgesics morphine; Right its uses the side effect that but brings weight not wait to the patient, and the formality of taking of narcotics also is that certain trouble is arranged.
Chinese medicine thinks that cancer pain is because between the poly-internal organs of pathogens such as expectorant, the stasis of blood, poison knot, malicious root lies prostrate deeply, checks not go for a long time, so that the meridians obturation, QI and blood is retarded by silt and is formed, and is different from the pain that other diseases causes.
The present invention relies on theory of Chinese medical science, and with promoting blood circulation to remove blood stasis, the side of strengthening vital QI to eliminate pathogenic factors separates the hardship of cancer pain, and clinical checking proof among a small circle is effective really.
Technical scheme
The present invention aims to provide a kind of curative effect height, the Chinese medicine analgesics that toxic and side effects is little.
Prescription: Herba Leonuri 100～120g, Colla carapax Trionycis 100～120g, Radix Ginseng 80～100g, the Radix Astragali 40～60g, Radix Et Rhizoma Rhei 40～60g, Flos Carthami 10～20g, Hirudo (system) 10～20g, Radix Angelicae Sinensis 20～40g, Lignum Sappan 10～20g, Rhizoma Anemones Raddeanae 10～20g, Rhizoma Chuanxiong 10～20g, Moschus 10～20g, Rhizoma Curcumae Longae 10～20g, Semen Armeniacae Amarum 20～40g, Myrrha 10～20g, Olibanum 10～20g, Scorpio 10～20g, Rhizoma Corydalis 20～40g, Semen Persicae 20～40g, Pollen Typhae (charcoal) 10～20g, Fructus Evodiae (liquorice beverage is processed) 10～20g, Resina Ferulae 10～20g, Cortex Cinnamomi 10～20g, Sanguis Draxonis 10～20g, Spina Gleditsiae 10～20g, Radix Rehmanniae Preparata 20～40g, the Radix Paeoniae Alba 20～40g, Oletum Trogopterori (processed with vinegar) 10～20g.
Method for making: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
Side's purport: removing blood stasis pain relievings such as Hirudo, Scorpio; Spina Gleditsiae, the blood stasis dispelling of Rhizoma Curcumae Longae eliminating stagnation, removing obstruction in the collateral to relieve pain; That Sanguis Draxonis, Oletum Trogopterori reduce phlegm is long-pending, promoting blood circulation, separate stagnation of QI, removing blood stasis collateral dredging; Carapax Trionycis belongs to the product that flesh and blood is deposited bone, replenishing vital essence and blood body fluid, nourishing YIN to relieve dryness; Cooperating the holy Chinese angelica blood supplementing enrich blood and not dry, is QI invigorating QI invigorating good medicine; Assistant strengthens the merit of nourishing YIN to relieve dryness with the Radix Paeoniae Alba, Radix Rehmanniae Preparata; Radix Ginseng contains the ginsenoside, has the effect that promotes immunity; Reuse Radix Ginseng, yellow Stilbene, be intended to strengthening vital QI to eliminate pathogenic factors; Moschus not only removing blood stasis Edgeworthia chrysantha Lindl. is scurried to drawing, and opens all medicines; The regulating menstruation collateral dredging, the Tibetan medicine transdermal; All medicines share have heat-clearing and toxic substances removing, the effect of promoting blood circulation to remove blood stasis, pain relieving softening the hard mass strengthening vital QI to eliminate pathogenic factors.Through clinical verification, this product is effective in cure good, steady quality, advantages such as taking convenience.
Clinical application effect: press the cancer patient of clinical definite, 62 examples, wherein male 42 examples, women 20 examples, 53～78 years old age, the course of disease 1～5 year.Give to take every day 2 times, take 1 bag at every turn.Do not take other analgesic during the treatment.The criterion of therapeutical effect that therapeutic outcome is worked out by national tumor Professional Committee pain association group is judged.With before the treatment relatively, the pain no change is invalid, pain relief 60% be that part is alleviated with in, pain relief 61%～90% be significantly alleviation, pain relief 91%～100% is alleviation fully.62 persons that take this granule as a result, total cancer pain remission rate (alleviating fully+significantly alleviate) is 93.5% (58/62); Be 100% (10/10) to the mild pain remission rate wherein, the moderate remission rate is that 95.3%941/430 severe pain remission rate is 77.8% (7/9).
Embodiment 1
Prescription: Herba Leonuri 112g, Colla carapax Trionycis 112g, Radix Ginseng 82g, Radix Astragali 42g, Radix Et Rhizoma Rhei 56g, Flos Carthami 14g, Hirudo (system) 14g, Radix Angelicae Sinensis 28g, Lignum Sappan 14g, Rhizoma Anemones Raddeanae 14g, Rhizoma Chuanxiong 14g, Moschus 14g, Rhizoma Curcumae Longae 14g, Semen Armeniacae Amarum 21g, Myrrha 14g, Olibanum 14g, Scorpio 14g, Rhizoma Corydalis 28g, Semen Persicae 21g, Pollen Typhae (charcoal) 14g, Fructus Evodiae (liquorice beverage is processed) 14g, Resina Ferulae 14g, Cortex Cinnamomi 14g, Sanguis Draxonis 14g, Spina Gleditsiae 14g, Radix Rehmanniae Preparata 28g, Radix Paeoniae Alba 28g, Oletum Trogopterori (processed with vinegar) 14g.
Method for making: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
Embodiment 2
Prescription: Herba Leonuri 100g, Colla carapax Trionycis 120g, Radix Ginseng 80g, Radix Astragali 60g, Radix Et Rhizoma Rhei 40g, Flos Carthami 20g, Hirudo (system) 10g, Radix Angelicae Sinensis 40g, Lignum Sappan 10g, Rhizoma Anemones Raddeanae 20g, Rhizoma Chuanxiong 10g, Moschus 20g, Rhizoma Curcumae Longae 10g, Semen Armeniacae Amarum 40g, Myrrha 10g, Olibanum 20g, Scorpio 10g, Rhizoma Corydalis 40g, Semen Persicae 20g, Pollen Typhae (charcoal) 20g, Fructus Evodiae (liquorice beverage is processed) 10g, Resina Ferulae 20g, Cortex Cinnamomi 10g, Sanguis Draxonis 20g, Spina Gleditsiae 10g, Radix Rehmanniae Preparata 40g, Radix Paeoniae Alba 20g, Oletum Trogopterori (processed with vinegar) 20g.
Method for making: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
Embodiment 3
Prescription: Herba Leonuri 120g, Colla carapax Trionycis 100g, Radix Ginseng 100g, Radix Astragali 40g, Radix Et Rhizoma Rhei 60g, Flos Carthami 10g, Hirudo (system) 20g, Radix Angelicae Sinensis 20g, Lignum Sappan 20g, Rhizoma Anemones Raddeanae 10g, Rhizoma Chuanxiong 20g, Moschus 10g, Rhizoma Curcumae Longae 20g, Semen Armeniacae Amarum 20g, Myrrha 20g, Olibanum 10g, Scorpio 20g, Rhizoma Corydalis 20g, Semen Persicae 40g, Pollen Typhae (charcoal) 10g, Fructus Evodiae (liquorice beverage is processed) 20g, Resina Ferulae 10g, Cortex Cinnamomi 20g, Sanguis Draxonis 10g, Spina Gleditsiae 20g, Radix Rehmanniae Preparata 20g, Radix Paeoniae Alba 40g, Oletum Trogopterori (processed with vinegar) 10.
Method for making: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
Claims (2)
1. plant blood-activating analgetic granule and preparation method thereof; Its prescription is: Herba Leonuri 100～120g, Colla carapax Trionycis 100～120g, Radix Ginseng 80～100g, the Radix Astragali 40～60g, Radix Et Rhizoma Rhei 40～60g, Flos Carthami 10～20g, Hirudo (system) 10～20g, Radix Angelicae Sinensis 20～40g, Lignum Sappan 10～20g, Rhizoma Anemones Raddeanae 10～20g, Rhizoma Chuanxiong 10～20g, Moschus 10～20g, Rhizoma Curcumae Longae 10～20g, Semen Armeniacae Amarum 20～40g, Myrrha 10～20g, Olibanum 10～20g, Scorpio 10～20g, Rhizoma Corydalis 20～40g, Semen Persicae 20～40g, Pollen Typhae (charcoal) 10～20g, Fructus Evodiae (liquorice beverage is processed) 10～20g, Resina Ferulae 10～20g, Cortex Cinnamomi 10～20g, Sanguis Draxonis 10～20g, Spina Gleditsiae 10～20g, Radix Rehmanniae Preparata 20～40g, the Radix Paeoniae Alba 20～40g, Oletum Trogopterori (processed with vinegar) 10～20g; Its method for making is: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
2. blood-activating analgetic granule according to claim 1 and preparation method thereof, its prescription is: Herba Leonuri 112g, Colla carapax Trionycis 112g, Radix Ginseng 82g, Radix Astragali 42g, Radix Et Rhizoma Rhei 56g, Flos Carthami 14g, Hirudo (system) 14g, Radix Angelicae Sinensis 28g, Lignum Sappan 14g, Rhizoma Anemones Raddeanae 14g, Rhizoma Chuanxiong 14g, Moschus 14g, Rhizoma Curcumae Longae 14g, Semen Armeniacae Amarum 21g, Myrrha 14g, Olibanum 14g, Scorpio 14g, Rhizoma Corydalis 28g, Semen Persicae 21g, Pollen Typhae (charcoal) 14g, Fructus Evodiae (liquorice beverage is processed) 14g, Resina Ferulae 14g, Cortex Cinnamomi 14g, Sanguis Draxonis 14g, Spina Gleditsiae 14g, Radix Rehmanniae Preparata 28g, Radix Paeoniae Alba 28g, Oletum Trogopterori (processed with vinegar) 14g.Its method for making is: (1) except that Resina Ferulae, Radix Rehmanniae Preparata, Colla carapax Trionycis, Sanguis Draxonis, Moschus, all the other 23 flavor medicine mixings are got 310g, are ground into fine powder; (2) remainder and Herba Leonuri water decoct twice, filter merging filtrate; (3) after the adding Colla carapax Trionycis dissolves in the filtrate, be condensed into thick paste; (4) Resina Ferulae water heating and melting filters; (5) Radix Rehmanniae Preparata decocting extracting juice filters; (6) merging filtrate is concentrated into thick paste; (7) two cream merge, and fine powders such as adding, Moschus are mixed drying thoroughly, are ground into fine powder; (8) use alcohol granulation, dry, mixing are made 200 bags.
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| CN 03144224 CN1589839A (en) | 2003-09-01 | 2003-09-01 | Stasis transforming pain relieving particle agent and its preparation method |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100348262C (en) * | 2005-03-30 | 2007-11-14 | 何周荣 | Medicinal composition for treating soreness, its preparation method and application |
| CN102085245A (en) * | 2011-01-20 | 2011-06-08 | 中南大学 | Traditional Chinese medicine with functions of treating drug addiction, healing wounds and relieving cancer pain |
| CN102671140A (en) * | 2011-12-01 | 2012-09-19 | 成都地奥集团天府药业股份有限公司 | Anticancer traditional Chinese medicine combination oral liquid, preparation method and detection method thereof |
| CN102805848A (en) * | 2012-07-16 | 2012-12-05 | 李丽红 | Chinese medicinal composition for treating dysmenorrhea |
| CN104069423A (en) * | 2013-03-27 | 2014-10-01 | 成都地奥集团天府药业股份有限公司 | A traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof |
| CN105477557A (en) * | 2016-01-04 | 2016-04-13 | 成都富豪斯生物科技有限公司 | Decoction drug for treating Qi-blood deficiency and blood stasis type diabetic foot and preparation method |
-
2003
- 2003-09-01 CN CN 03144224 patent/CN1589839A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100348262C (en) * | 2005-03-30 | 2007-11-14 | 何周荣 | Medicinal composition for treating soreness, its preparation method and application |
| CN102085245A (en) * | 2011-01-20 | 2011-06-08 | 中南大学 | Traditional Chinese medicine with functions of treating drug addiction, healing wounds and relieving cancer pain |
| CN102085245B (en) * | 2011-01-20 | 2011-12-28 | 中南大学 | Traditional Chinese medicine with functions of treating drug addiction, healing wounds and relieving cancer pain |
| CN102671140A (en) * | 2011-12-01 | 2012-09-19 | 成都地奥集团天府药业股份有限公司 | Anticancer traditional Chinese medicine combination oral liquid, preparation method and detection method thereof |
| CN102671140B (en) * | 2011-12-01 | 2013-03-06 | 成都地奥集团天府药业股份有限公司 | Anticancer traditional Chinese medicine combination oral liquid, preparation method and detection method thereof |
| CN102805848A (en) * | 2012-07-16 | 2012-12-05 | 李丽红 | Chinese medicinal composition for treating dysmenorrhea |
| CN104069423A (en) * | 2013-03-27 | 2014-10-01 | 成都地奥集团天府药业股份有限公司 | A traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof |
| CN104069423B (en) * | 2013-03-27 | 2017-05-24 | 成都地奥集团天府药业股份有限公司 | A traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof |
| CN105477557A (en) * | 2016-01-04 | 2016-04-13 | 成都富豪斯生物科技有限公司 | Decoction drug for treating Qi-blood deficiency and blood stasis type diabetic foot and preparation method |
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