CN1404854A - Medicine for treating nosal inflammation - Google Patents
Medicine for treating nosal inflammation Download PDFInfo
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- CN1404854A CN1404854A CN 02100299 CN02100299A CN1404854A CN 1404854 A CN1404854 A CN 1404854A CN 02100299 CN02100299 CN 02100299 CN 02100299 A CN02100299 A CN 02100299A CN 1404854 A CN1404854 A CN 1404854A
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Abstract
The present ivnention discloses a medicine for curing acute and chronic rhinitis and nasal sinusitis. Said medicine preparation is made up by using 15 Chinese medicinal materials of magnolia flower, xanthium fruit, lonicera flower, centipeda, acorus root and others as main raw material and Western medicine chlorpheniramine maleate as auxiliary raw material.
Description
The present invention relates to be used for the treatment of the medicine of acute and chronic rhinitis, sinusitis, particularly is the pharmaceutical preparation of main preparation with the Chinese crude drug.
Rhinitis, sinusitis are frequently-occurring disease, the commonly encountered diseases among the crowd.To show as the course of disease long more, and easily recurrence brings a lot of inconvenience for patient's living and studying.At present the treatment of rhinitis, sinusitis is not still had special-purpose specific medicament, use general anti-inflammation drugs and symptomatic treatment more.The treatment acute and chronic rhinitis of selling on the market, the medicine of sinusitis can't be satisfactory at aspects such as effective percentage, persistency, relapse rates.Its deficiency is, or can not be effective to everyone, or relapse rate is higher after stopping using medicine.Therefore be necessary to excavate more effective, easy to use, cheap treatment acute and chronic rhinitis, the medicine of sinusitis.And its unique advantage and value is arranged according to the medicine of the theoretical development of Chinese medicine and pharmacy.
The object of the present invention is to provide a kind of serves as the pharmaceutical preparation of main preparation with the Chinese medicine natural drug, and it can reach treating both the principal and secondary aspects of a disease aspect treatment acute and chronic rhinitis, sinusitis, better curative effect is arranged.
The present invention seeks to realize by the following method.
Crude drug of the present invention is equipped with a small amount of Western medicine chlorphenamine (Chlorpheniraminum) based on 15 kinds of Chinese medicine natural drugs.15 kinds of Chinese medicines are Flos Magnoliae flower, Fructus Xanthii, Flos Lonicerae, Herba Centipedae, Rhizoma Acori Graminei, Herba Pogostemonis, Folium Perillae, Herba Menthae, Radix Gentianae, Radix Bupleuri, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Platycodonis, Herba Houttuyniae, Radix Scutellariae.They are equipped with the pharmacy acceptable carrier, adopt common process, manufacture capsule, oral liquid or other dosage forms that is suitable for.
Pharmaceutical compositions consumption proportion scope of the present invention is: Flos Magnoliae is spent 10～14% Fructus Xanthii, 8～12% Flos Loniceraes, 6～11% Herba Centipedae, 6～11% Rhizoma Acori Gramineis, 3～7% Herba Pogostemoniss, 4～9% Folium Perillaes, 3～8% Herba Menthaes, 3～7% Radix Gentianaes, 4～9% Radix Bupleuri, 4～9% Rhizoma Chuanxiongs, 4～9% Radixs Angelicae Dahuricae, 3～7% Radix Platycodoniss, 3～7% Herba Houttuyniae, 6～11% Radix Scutellariaes, 3～7% chlorphenamines 0.1～0.4%
Pharmaceutical compositions consumption optimum ratio of the present invention is: Flos Magnoliae is spent 11～12% Fructus Xanthii, 9～11% Flos Loniceraes, 7～9% Herba Centipedae, 7～9% Rhizoma Acori Gramineis, 4～6% Herba Pogostemoniss, 5～7% Folium Perillaes, 4～6% Herba Menthaes, 4～6% Radix Gentianaes, 5～7% Radix Bupleuri, 5～7% Rhizoma Chuanxiongs, 5～7% Radixs Angelicae Dahuricae, 4～6% Radix Platycodoniss, 4～6% Herba Houttuyniae, 7～9% Radix Scutellariaes, 4～6% chlorphenamines 0.1～0.2%
The best proportioning of ingredient consumption of the present invention is: Flos Magnoliae is spent 12% Fructus Xanthii, 10% Flos Lonicerae, 8% Herba Centipedae, 8% Rhizoma Acori Graminei, 5% Herba Pogostemonis, 6% Folium Perillae, 5% Herba Menthae, 5% Radix Gentianae, 6% Radix Bupleuri, 6% Rhizoma Chuanxiong, 6% Radix Angelicae Dahuricae, 5% Radix Platycodonis, 5% Herba Houttuyniae, 7.8% Radix Scutellariae, 5% chlorphenamine 0.2%
Formulation method:
The Chinese medicine preprocessing need only be pulverized Fructus Xanthii.
1. glue wafer.Except that chlorphenamine and Herba Menthae, with all the other 14 kinds of Chinese medicine mixing watered boilings 3 times, decocted 1～3 hour at every turn, cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 20～40 minutes; Merge each time decoction liquor, reheat is condensed into paste, dries then or dries, and row is pulverized again, drops into chlorphenamine, and mix homogeneously incapsulates, and is finished product.
2. system oral liquid.Except that chlorphenamine and Herba Menthae, with all the other 14 kinds of Chinese medicine mixing watered boilings 3 times, decocted 1～3 hour at every turn, cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 20～40 minutes; Merge each time decoction liquor, add chlorphenamine and antiseptic, packing is standby.
3. also can make dosage forms such as tablet, honeyed pill, the watered pill, granular pattern electuary by usual way.
More than various dosage forms adult consumptions every day be equivalent to crude drug 120～160 grams, divide and take for 2～3 times.
Motherland's medical science thinks, rhinitis, sinusitis are many because of the evil poison of diseases caused by exogenous pathogenic factor, wind and heat in the lung meridian, and the gallbladder internal organs is hot and suffocating, the damp-heat in the spleen and stomach circulation criminal's of going up intrusion nasal sinuses and sending out.Clinical manifestation is nasal obstruction, the nasal mucus of suppurating, headache and general malaise.In the prescription of the present invention Flos Magnoliae flower, Fructus Xanthii, Herba Centipedae dispel the wind, the sharp key of pain relieving, stuffy nose relieving; Flos Lonicerae, Herba Houttuyniae, Herba Pogostemonis, the bath of Radix Angelicae Dahuricae dispelling wind are wet, heat-clearing and toxic substances removing, detumescence and apocenosis; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Platycodonis ascending lung qi, priming are up.All medicines share, and play altogether that the bath of dispeling the wind is wet, the effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the sharp key of stuffy nose relieving.Add an amount of chlorphenamine again,, reach treating both the principal and secondary aspects of a disease, the purpose that As the medicine took effect, the symptoms lessened with the effect of the antiallergic action of strengthening pure Chinese medicine.
The inventor uses the various acute and chronic rhinitis of Drug therapy of the present invention, allergic rhinitis, the tens of examples of sinusitis.Wherein 18 complete examples of collection of data are carried out statistical analysis, satisfactory effect.Male's 12 examples wherein, women's 6 examples; The oldest 42 years old, minimum 8 years old.The course of disease is the longest 3 months, and is the shortest 12 days.Clinical manifestation such as all cases all have in various degree nasal obstruction, watery nasal discharge, nasal mucosa redness, hyposmia, feel dizzy.Fully recover after 8～16 days through taking medicine of the present invention.The tracing study several months, rare recurrence.
The invention will be further described by the following examples.
Embodiment 1 produces the capsule Flos Magnoliae and spends 240 gram Fructus Xanthii, 200 gram Flos Loniceraes, 160 gram Herba Centipedae, 160 gram Rhizoma Acori Gramineis, 100 gram Herba Pogostemoniss, 120 gram Folium Perillaes, 100 gram Herba Menthaes, 100 cron Radix Gentianae, 120 gram Radix Bupleuri, 120 gram Rhizoma Chuanxiongs, the 120 gram Radixs Angelicae Dahuricae, 100 gram Radix Platycodoniss, 100 gram Herba Houttuyniae, 160 gram Radix Scutellariaes, 100 gram chlorphenamines, 4 grams
Above crude drug is pulverized Fructus Xanthii except that chlorphenamine and Herba Menthae in advance, with all the other 13 kinds of Chinese medicine mixing watered boilings 3 times, decocts 1～3 hour at every turn, crosses the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 30 minutes; Merge each time decoction liquor, reheat is condensed into paste, oven dry then, and row is pulverized again, drops into chlorphenamine, and mix homogeneously incapsulates, and is finished product.
The total consumption of present embodiment crude drug is 2004 grams, is equivalent to crude drug 120～160 grams by adult's consumption every day and calculates, and is equivalent to the consumption in 2 weeks of adult patient (14 days) approximately.
Embodiment 2 produces the oral liquid Flos Magnoliae and spends 220 gram Fructus Xanthii, 220 gram Flos Loniceraes, 140 gram Herba Centipedae, 180 gram Rhizoma Acori Gramineis, 80 gram Herba Pogostemoniss, 140 gram Folium Perillaes, 90 gram Herba Menthaes, 120 cron Radix Gentianae, 100 gram Radix Bupleuri, 140 gram Rhizoma Chuanxiongs, the 100 gram Radixs Angelicae Dahuricae, 120 gram Radix Platycodoniss, 80 gram Herba Houttuyniae, 180 gram Radix Scutellariaes, 100 gram chlorphenamines, 3 grams
Above crude drug is pulverized Fructus Xanthii except that chlorphenamine and Herba Menthae in advance, and with all the other 13 kinds of Chinese medicine mixing watered boilings 3 times, each time decocting time was respectively 3 hours, 2 hours, 1 hour.Cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 30 minutes; Merge each time decoction liquor, add chlorphenamine and antiseptic, mix homogeneously, packing is finished product.
The total consumption of present embodiment crude drug is 2013 grams, is equivalent to crude drug 120～160 grams by adult's consumption every day and calculates, and is equivalent to the consumption in 2 weeks of adult patient (14 days) approximately.
Embodiment 3 produces the capsule Flos Magnoliae and spends 260 gram Fructus Xanthii, 160 gram Flos Loniceraes, 220 gram Herba Centipedae, 120 gram Rhizoma Acori Gramineis, 100 gram Herba Pogostemoniss, 120 gram Folium Perillaes, 100 gram Herba Menthaes, 140 cron Radix Gentianae, 90 gram Radix Bupleuri, 160 gram Rhizoma Chuanxiongs, the 140 gram Radixs Angelicae Dahuricae, 100 gram Radix Platycodoniss, 90 gram Herba Houttuyniae, 160 gram Radix Scutellariaes, 100 gram chlorphenamines, 2.5 grams
Above crude drug is pulverized Fructus Xanthii except that chlorphenamine and Herba Menthae in advance, and with all the other 13 kinds of Chinese medicine mixing watered boilings 3 times, each time decocting time was respectively 3 hours, 2.5 hours, 2 hours.Cross the leaching decoction liquor; The leaching decoction liquor was crossed in the Herba Menthae watered boiling in 20 minutes; Merge each time decoction liquor, reheat is condensed into paste, dries then, and row is pulverized again, drops into chlorphenamine, and mix homogeneously incapsulates, and is finished product.
The total consumption of present embodiment crude drug is 2062.5 grams, is equivalent to crude drug 120～160 grams by adult's consumption every day and calculates, and is equivalent to the consumption in 2 weeks of adult patient (14 days) approximately.
Claims (7)
1. one kind serves as the treatment acute and chronic rhinitis of main preparation, the pharmaceutical preparation of sinusitis with the Chinese medicine natural drug, it is characterized in that, it is made by following proportion raw material medicine, and Flos Magnoliae is spent 10～14% Fructus Xanthii, 8～12% Flos Loniceraes, 6～11% Herba Centipedae, 6～11% Rhizoma Acori Gramineis, 3～7% Herba Pogostemoniss, 4～9% Folium Perillaes, 3～8% Herba Menthaes, 3～7% Radix Gentianaes, 4～9% Radix Bupleuri, 4～9% Rhizoma Chuanxiongs, 4～9% Radixs Angelicae Dahuricae, 3～7% Radix Platycodoniss, 3～7% Herba Houttuyniae 6-11% Radix Scutellariaes, 3～7% chlorphenamines 0.1～0.4%
2. pharmaceutical preparation according to claim 1, it is characterized in that, the consumption proportion of each crude drug is that Flos Magnoliae is spent 11～12% Fructus Xanthii, 9～11% Flos Loniceraes, 7～9% Herba Centipedae, 7～9% Rhizoma Acori Gramineis, 4～6% Herba Pogostemoniss, 5～7% Folium Perillaes, 4～6% Herba Menthaes, 4～6% Radix Gentianaes, 5～7% Radix Bupleuri, 5～7% Rhizoma Chuanxiongs, 5～7% Radixs Angelicae Dahuricae, 4～6% Radix Platycodoniss, 4～6% Herba Houttuyniae, 7～9% Radix Scutellariaes, 4～6% chlorphenamines 0.1～0.3%
3. pharmaceutical preparation according to claim 1, it is characterized in that, the consumption proportion of each crude drug is that Flos Magnoliae is spent 12% Fructus Xanthii, 10% Flos Lonicerae, 8% Herba Centipedae, 8% Rhizoma Acori Graminei, 5% Herba Pogostemonis, 6% Folium Perillae, 5% Herba Menthae, 5% Radix Gentianae, 6% Radix Bupleuri, 6% Rhizoma Chuanxiong, 6% Radix Angelicae Dahuricae, 5% Radix Platycodonis, 5% Herba Houttuyniae, 7.8% Radix Scutellariae, 5% chlorphenamine 0.2%
4. according to claim 1 and 2 and 3 described pharmaceutical preparatioies, it is characterized in that said medicament is a said dosage form on any pharmaceutics.
5. pharmaceutical preparation according to claim 4 is characterized in that, said medicament is capsule or oral liquid.
6. the preparation method of pharmaceutical preparation according to claim 5, it is characterized in that, 14 kinds of decocting for Chinese herbal medicine except that chlorphenamine and Herba Menthae 3 times, Herba Menthae decocted 20～40 minutes, crossed the leaching decoction liquor and merged, reheat is condensed into cream, dry then or dry, row is pulverized again, drops into chlorphenamine, mix homogeneously incapsulates.
7. the preparation method of pharmaceutical preparation according to claim 5 is characterized in that, 14 kinds of decocting for Chinese herbal medicine except that chlorphenamine and Herba Menthae 3 times, and Herba Menthae decocted 20～40 minutes, crossed the leaching decoction liquor and merged, and added chlorphenamine and antiseptic, was distributed into oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021002991A CN1166388C (en) | 2002-01-18 | 2002-01-18 | Medicine for treating nosal inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021002991A CN1166388C (en) | 2002-01-18 | 2002-01-18 | Medicine for treating nosal inflammation |
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| Publication Number | Publication Date |
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| CN1404854A true CN1404854A (en) | 2003-03-26 |
| CN1166388C CN1166388C (en) | 2004-09-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021002991A Expired - Fee Related CN1166388C (en) | 2002-01-18 | 2002-01-18 | Medicine for treating nosal inflammation |
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| CN (1) | CN1166388C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100393338C (en) * | 2006-02-24 | 2008-06-11 | 徐利洪 | Ointment for treating rhinitis and preparing method |
| CN100425224C (en) * | 2006-12-04 | 2008-10-15 | 刘粉叶 | Chinese medicinal nasal wash and preparation method thereof |
| CN101181408B (en) * | 2007-11-30 | 2010-10-06 | 李福强 | Chinese medicine composition for the oral medication of chronic sinusitis |
| CN101342277B (en) * | 2008-08-19 | 2011-04-06 | 冯苏涛 | Externally used antimicrobial spray for treating snore and preparation method thereof |
| CN102743731A (en) * | 2012-07-14 | 2012-10-24 | 尤秀真 | Chinese medicament for treating chronic rhinitis |
| CN103830564A (en) * | 2014-03-10 | 2014-06-04 | 宁波大学 | Oral medicine for treating chronic nasosinusitis |
| CN104398964A (en) * | 2014-12-01 | 2015-03-11 | 郭文喜 | Traditional Chinese medicinal composition for treating allergic rhinitis |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332279B (en) * | 2008-07-15 | 2010-09-08 | 何社明 | Traditional Chinese medicine preparation for treating nasal sinusitis, rhinopolypus and nasopharyngitis |
| CN102018838A (en) * | 2010-11-15 | 2011-04-20 | 张英堂 | Medicine for treating chronic rhinitis |
-
2002
- 2002-01-18 CN CNB021002991A patent/CN1166388C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100393338C (en) * | 2006-02-24 | 2008-06-11 | 徐利洪 | Ointment for treating rhinitis and preparing method |
| CN100425224C (en) * | 2006-12-04 | 2008-10-15 | 刘粉叶 | Chinese medicinal nasal wash and preparation method thereof |
| CN101181408B (en) * | 2007-11-30 | 2010-10-06 | 李福强 | Chinese medicine composition for the oral medication of chronic sinusitis |
| CN101342277B (en) * | 2008-08-19 | 2011-04-06 | 冯苏涛 | Externally used antimicrobial spray for treating snore and preparation method thereof |
| CN102743731A (en) * | 2012-07-14 | 2012-10-24 | 尤秀真 | Chinese medicament for treating chronic rhinitis |
| CN102743731B (en) * | 2012-07-14 | 2013-10-16 | 济南伟传信息技术有限公司 | Chinese medicament for treating chronic rhinitis |
| CN103830564A (en) * | 2014-03-10 | 2014-06-04 | 宁波大学 | Oral medicine for treating chronic nasosinusitis |
| CN103830564B (en) * | 2014-03-10 | 2017-01-04 | 宁波大学 | For treating the endo-medicine of chronic sinusitis |
| CN104398964A (en) * | 2014-12-01 | 2015-03-11 | 郭文喜 | Traditional Chinese medicinal composition for treating allergic rhinitis |
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| Publication number | Publication date |
|---|---|
| CN1166388C (en) | 2004-09-15 |
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