CN1739611A - Stasis relieving oral liquid for treating rhinitis and its prepn - Google Patents
Stasis relieving oral liquid for treating rhinitis and its prepn Download PDFInfo
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- CN1739611A CN1739611A CN 200510032109 CN200510032109A CN1739611A CN 1739611 A CN1739611 A CN 1739611A CN 200510032109 CN200510032109 CN 200510032109 CN 200510032109 A CN200510032109 A CN 200510032109A CN 1739611 A CN1739611 A CN 1739611A
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Abstract
The stasis relieving oral liquid for treating rhinitis is prepared with seven kinds of Chinese medicinal materials, including cocklebur fruit, ledebouriella root, astragalus root, dahurian angelica root, white atractylodes rhizome, etc. The present invention has the features of simple preparation process, low production cost, fast absorption, high bioavailability, high curative effect and less side effect.
Description
One, technical field:
The present invention relates to a kind ofly have QI invigorating, dispel the wind, sensible, be used for the medicine and preparation method thereof of the oral liquid formulation of the empty spontaneous perspiration of body, repeated cold, nasal obstruction, watery nasal discharge.The present invention is to be medicine of the oral liquid formulation made of active component and preparation method thereof with Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, the Radix Angelicae Dahuricae, Flos Magnoliae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Herba Menthae 7 flavor Chinese medicines, relates in particular to stasis relieving oral liquid for treating rhinitis and preparation method thereof.
Two, background technology:
TONGXIAO BIYAN PIAN has QI invigorating, dispels the wind, sensible effect, is used for the treatment of diseases such as the empty spontaneous perspiration of body, repeated cold, nasal obstruction, watery nasal discharge.This tablet has been taken in Chinese Pharmacopoeia, through clinical verification for many years, and its steady quality, determined curative effect is the common drug preparation that is used for the treatment of above-mentioned disease clinically.The TONGXIAO BIYAN PIAN agent is as a kind of electuary, its complex manufacturing technology; Disintegration time is long, and is not easy dissolving fully, is unfavorable for absorbing; Absorb slowly, cause bioavailability to reduce; Dose is big, and the patient is not easy to accept, tablet easily under one's belt the time of staying long, easy stimulating intestine and stomach causes side effect.
Three, summary of the invention:
The object of the present invention is to provide a kind of is the medicine and preparation method thereof of the oral liquid formulation made of active component with Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, the Radix Angelicae Dahuricae, Flos Magnoliae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Herba Menthae 7 flavor Chinese medicines.
Technical scheme of the present invention is: a kind of stasis relieving oral liquid for treating rhinitis, by following traditional Chinese medicines by weight component add purified water and correctives is formulated, its component is: Fructus Xanthii (stir-fry) 1-8 part, Radix Saposhnikoviae 1-6 part, Radix Astragali 1-10 part, Radix Angelicae Dahuricae 1-6 part, Flos Magnoliae 1-6 part, the Rhizoma Atractylodis Macrocephalae (stir-fry) 1-6 part, Herba Menthae 1-3 part; Best component is: 4 parts of Fructus Xanthii (stir-fry), 3 parts of Radix Saposhnikoviaes, 5 parts of the Radixs Astragali, 3 parts of the Radixs Angelicae Dahuricae, 3 parts of Flos Magnoliaes, 3 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 1 part of Herba Menthae.
Preparation method of the present invention is:
A, get Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, the Radix Angelicae Dahuricae, Flos Magnoliae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Herba Menthae 7 flavor Chinese medicines and clean,, be broken into fine powder through being up to the standards;
B, Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae 2 flavor fine powders are fully mixed, the ethanol with 60%-80% carries out alcohol extraction 3 times, the 1st adding of alcohol extraction amount of alcohol is 3-6 a times of drug weight, 2 hours time, the 2nd 2-4 doubly, 1.5 hours time, the 3rd time 2 times, 1 hour time, merge extractive liquid, reclaims ethanol, filter, get filtrate and medicinal residues; Filtrate suitably concentrates, and gets concentrated solution A;
C, the medicinal residues of getting the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae and all the other Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, Flos Magnoliae, Herba Menthae 5 flavor Chinese medicines mix, decoct with water 3 times, the 4-12 that decocts amount of water for the 1st time and be drug weight doubly, decocted 3 hours, the 2nd time amount of water is 4-10 times, decocted 2 hours, the 3rd time amount of water is 4-8 times, decocts 1 hour; Collecting decoction filters, and gets filtrate, suitably concentrates, and gets concentrated solution B;
D, with concentrated solution A and the abundant mix homogeneously of B, add suitable quantity of water and correctives, mix homogeneously.Promptly get oral liquid of the present invention.
Four, the specific embodiment:
Embodiment 1: get Fructus Xanthii (stir-fry) 120 grams, Radix Saposhnikoviae 90 grams, the Radix Astragali 150 grams, the Radix Angelicae Dahuricae 90 grams, Flos Magnoliae 90 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 90, Herba Menthae 30 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 1000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 2: get Fructus Xanthii (stir-fry) 120 grams, Radix Saposhnikoviae 90 grams, the Radix Astragali 150 grams, the Radix Angelicae Dahuricae 90 grams, Flos Magnoliae 90 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 90, Herba Menthae 30 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 500 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 3: get Fructus Xanthii (stir-fry) 120 grams, Radix Saposhnikoviae 90 grams, the Radix Astragali 150 grams, the Radix Angelicae Dahuricae 90 grams, Flos Magnoliae 90 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 90, Herba Menthae 30 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 2000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 4: get Fructus Xanthii (stir-fry) 120 grams, Radix Saposhnikoviae 90 grams, the Radix Astragali 150 grams, the Radix Angelicae Dahuricae 90 grams, Flos Magnoliae 90 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 90, Herba Menthae 30 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 3000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 5: get Fructus Xanthii (stir-fry) 120 grams, Radix Saposhnikoviae 90 grams, the Radix Astragali 150 grams, the Radix Angelicae Dahuricae 90 grams, Flos Magnoliae 90 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 90, Herba Menthae 30 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 4000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 6: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 1000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 7: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 500 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 8: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 2000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 9: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 3000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 10: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 4000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 11: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 6000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Embodiment 12: get Fructus Xanthii (stir-fry) 240 grams, Radix Saposhnikoviae 180 grams, the Radix Astragali 300 grams, the Radix Angelicae Dahuricae 180 grams, Flos Magnoliae 180 grams, the Rhizoma Atractylodis Macrocephalae (stir-fry) 180, Herba Menthae 60 grams.According to stasis relieving oral liquid for treating rhinitis preparation method in the technique scheme, make 8000 milliliters, sterilization, fill becomes 10 milliliters or 20 milliliters of chest discomfort treating oral liquids.
Claims (2)
1, a kind of stasis relieving oral liquid for treating rhinitis, by following traditional Chinese medicines by weight component add purified water and correctives is formulated, its component is: Fructus Xanthii (stir-fry) 1-8 part, Radix Saposhnikoviae 1-6 part, Radix Astragali 1-10 part, Radix Angelicae Dahuricae 1-6 part, Flos Magnoliae 1-6 part, the Rhizoma Atractylodis Macrocephalae (stir-fry) 1-6 part, Herba Menthae 1-3 part; Best component is: 4 parts of Fructus Xanthii (stir-fry), 3 parts of Radix Saposhnikoviaes, 5 parts of the Radixs Astragali, 3 parts of the Radixs Angelicae Dahuricae, 3 parts of Flos Magnoliaes, 3 parts of the Rhizoma Atractylodis Macrocephalaes (stir-fry), 1 part of Herba Menthae.
2, the preparation method of stasis relieving oral liquid for treating rhinitis according to claim 1 is characterized in that:
A, get Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, the Radix Angelicae Dahuricae, Flos Magnoliae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Herba Menthae 7 flavor Chinese medicines and clean,, be broken into fine powder through being up to the standards;
B, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae 2 flavor fine powders are fully mixed, the ethanol with 60%-80% carries out alcohol extraction 3 times, alcohol extraction add for the 1st time amount of alcohol be drug weight 3-6 doubly, 2 hours time, the 2nd 2-4 doubly, 1.5 hours time, the 3rd time 2 times, 1 hour time; Merge extractive liquid, reclaims ethanol, filters, and gets filtrate and medicinal residues; Filtrate suitably concentrates, and gets concentrated solution A;
C, the medicinal residues of getting the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae and Fructus Xanthii (stir-fry), Radix Saposhnikoviae, the Radix Astragali, Flos Magnoliae, Herba Menthae 5 flavor Chinese medicines mix, decoct with water 3 times, the 4-12 that decocts amount of water for the 1st time and be drug weight doubly, decocted 3 hours, the 2nd time amount of water is 4-10 times, decocted 2 hours, the 3rd time amount of water is 4-8 times, decocts 1 hour; Collecting decoction filters, and gets filtrate, suitably concentrates, and gets concentrated solution B;
D, with concentrated solution A and the abundant mix homogeneously of B, add suitable quantity of water and correctives, mix homogeneously.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510032109 CN1739611A (en) | 2005-08-31 | 2005-08-31 | Stasis relieving oral liquid for treating rhinitis and its prepn |
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| CN 200510032109 CN1739611A (en) | 2005-08-31 | 2005-08-31 | Stasis relieving oral liquid for treating rhinitis and its prepn |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185673B (en) * | 2007-11-07 | 2011-01-12 | 李会敏 | Medicine for treating nasosinusitis |
| CN104000893A (en) * | 2014-06-21 | 2014-08-27 | 徐显廷 | Traditional Chinese medicine oral liquid for treating rhinitis |
| CN106361818A (en) * | 2016-11-04 | 2017-02-01 | 济宁沭康生物科技有限公司 | Nasal cavity restoration anti-bacterium oil |
| CN106581262A (en) * | 2016-12-06 | 2017-04-26 | 湖北省农业科学院果树茶叶研究所 | Rhinitis oral liquid containing EGCG and preparation method thereof |
| CN107669839A (en) * | 2017-10-25 | 2018-02-09 | 苏鑫 | A kind of Chinese medicine for treating allergic rhinitis |
| CN108837002A (en) * | 2018-09-26 | 2018-11-20 | 冯炜 | A kind of Chinese medicine composition and its preparation for treating allergic rhinitis |
| CN109125398A (en) * | 2018-11-22 | 2019-01-04 | 张瑞武 | A kind of sensible rhinitis particle |
| CN112618652A (en) * | 2020-12-25 | 2021-04-09 | 皖西学院 | Stachys polysaccharide oral liquid and preparation method thereof |
-
2005
- 2005-08-31 CN CN 200510032109 patent/CN1739611A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185673B (en) * | 2007-11-07 | 2011-01-12 | 李会敏 | Medicine for treating nasosinusitis |
| CN104000893A (en) * | 2014-06-21 | 2014-08-27 | 徐显廷 | Traditional Chinese medicine oral liquid for treating rhinitis |
| CN106361818A (en) * | 2016-11-04 | 2017-02-01 | 济宁沭康生物科技有限公司 | Nasal cavity restoration anti-bacterium oil |
| CN106581262A (en) * | 2016-12-06 | 2017-04-26 | 湖北省农业科学院果树茶叶研究所 | Rhinitis oral liquid containing EGCG and preparation method thereof |
| CN107669839A (en) * | 2017-10-25 | 2018-02-09 | 苏鑫 | A kind of Chinese medicine for treating allergic rhinitis |
| CN108837002A (en) * | 2018-09-26 | 2018-11-20 | 冯炜 | A kind of Chinese medicine composition and its preparation for treating allergic rhinitis |
| CN109125398A (en) * | 2018-11-22 | 2019-01-04 | 张瑞武 | A kind of sensible rhinitis particle |
| CN112618652A (en) * | 2020-12-25 | 2021-04-09 | 皖西学院 | Stachys polysaccharide oral liquid and preparation method thereof |
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Open date: 20060301 |