CN112057573A - Traditional Chinese medicine composition for treating cough and preventing haze and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating cough and preventing haze and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a method for relieving cough and resisting haze, in particular to a traditional Chinese medicine composition for treating cough and preventing haze and a preparation method thereof; comprises a first component, a second component and a third component, wherein the first component comprises: 12-16 parts of Chinese yam, 8-12 parts of angelica, 10-12 parts of salvia miltiorrhiza, 8-12 parts of radix ophiopogonis, 8-16 parts of houttuynia cordata, 8-12 parts of aster, 8-12 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis; the second component comprises 5 honeycombs and 10-12 parts of lithospermum, and the third component comprises 7-11 parts of pummelo peel; the anti-haze composition for treating cough provided by the invention is not limited to the product form, the raw material components are scientific and reasonable in proportion, and the components are synergistic, so that the anti-haze composition for preventing respiratory tract infection has an obvious effect on preventing the respiratory tract infection.
Description
Technical Field
The invention relates to a method for relieving cough and resisting haze, in particular to a traditional Chinese medicine composition for treating cough and preventing haze and a preparation method thereof.
Background
Haze is common weather in autumn and winter in northern China, and the damage to organisms in the haze weather is mainly caused by the fact that particulate matters smaller than 10 microns in air enter lungs through breathing and are deposited in the lungs. The particulate matter carries harmful substances such as pollutants, viruses and bacteria, so that lung damage can be caused, lung function is reduced, and diseases such as chronic bronchitis, emphysema and bronchial asthma can be caused. In addition to the fact that protective measures are taken for haze people, damage of haze to bodies can be reduced through diet adjustment, and therefore medicinal and edible traditional Chinese medicinal materials are particularly favored.
The medicinal and edible traditional Chinese medicinal materials are natural and safer than western medicines; and the traditional Chinese medicinal materials have wide sources and low prices. The traditional Chinese medicine formula theory is that on the basis of syndrome differentiation, the necessary dosage is regulated according to the seven emotions of the medicines according to the requirements of the state of an illness, and the medicines are combined to organize a formula, and the principle of the formula is divided into four parts of monarch, minister, assistant and guide. In recent years, pharmacological studies among various medicines in a traditional Chinese medicine compound show that the compatibility and formula application of the traditional Chinese medicines plays an important role in improving curative effect and reducing toxicity. Under the guidance of the theory of traditional Chinese medicine, the modern traditional Chinese medicine is prepared from traditional Chinese medicinal materials according to a scientific process, and then is prepared into a certain dosage form, and the dosage form is marked with functional indications, prescription composition, usage amount, incompatibility and the like, so that a patient can conveniently and directly take the traditional Chinese medicine preparation or a daily health-care food product.
Disclosure of Invention
In order to solve the technical problems, the invention provides a traditional Chinese medicine composition for treating cough and preventing haze,
the invention is realized by the following steps:
a traditional Chinese medicine composition for treating cough and preventing haze comprises a first component, a second component and a third component, wherein the first component comprises:
12-16 parts of Chinese yam, 8-12 parts of angelica, 10-12 parts of salvia miltiorrhiza, 8-12 parts of radix ophiopogonis, 8-16 parts of houttuynia cordata, 8-12 parts of aster, 8-12 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis.
Further, the second component comprises 5 honeycomb and 10-12 parts of lithospermum, and the third component comprises 7-11 parts of pummelo peel.
Further, the first component comprises 12-15 parts of Chinese yam, 8-11 parts of angelica, 10-12 parts of salvia miltiorrhiza, 8-11 parts of radix ophiopogonis, 8-14 parts of houttuynia cordata, 8-11 parts of aster, 8-11 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 10-12 parts of lithospermum, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis, and the third component comprises 7-10 parts of pummelo peel.
Further, the first component comprises 13-15 parts of Chinese yam, 9-11 parts of angelica, 10-12 parts of salvia miltiorrhiza, 9-11 parts of radix ophiopogonis, 10-14 parts of houttuynia cordata, 9-11 parts of aster, 9-11 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 10-12 parts of lithospermum, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis, and the third component comprises 8-10 parts of pummelo peel.
Further, the first component comprises 13 parts of Chinese yam, 9 parts of Chinese angelica, 10 parts of salvia miltiorrhiza, 9 parts of radix ophiopogonis, 10 parts of houttuynia cordata, 9 parts of aster, 9 parts of flos farfarae, 11 parts of trichosanthes kirilowii maxim, 8 parts of almond, 8 parts of codonopsis pilosula, 6 parts of rhizoma pinellinae praeparata, 6 parts of radix stemonae and 6 parts of fructus cannabis, the second component comprises 10 parts of lithospermum and 5 honeycombs, and the third component comprises 8 parts of pummelo peel.
Further, the first component comprises 15 parts of Chinese yam, 11 parts of Chinese angelica, 12 parts of salvia miltiorrhiza, 11 parts of radix ophiopogonis, 14 parts of houttuynia cordata, 11 parts of aster, 11 parts of common coltsfoot flower, 13 parts of snakegourd fruit, 10 parts of almond, 10 parts of codonopsis pilosula, 8 parts of rhizoma pinellinae praeparata, 9 parts of radix stemonae and 8 parts of fructus cannabis, the second component comprises 12 parts of lithospermum and 5 honeycomb parts, and the third component comprises 10 parts of pummelo peel.
Further, the first component comprises 14 parts of Chinese yam, 10 parts of Chinese angelica, 11 parts of salvia miltiorrhiza, 10 parts of radix ophiopogonis, 12 parts of houttuynia cordata, 10 parts of aster, 10 parts of flos farfarae, 12 parts of trichosanthes kirilowii maxim, 9 parts of almond, 9 parts of codonopsis pilosula, 7 parts of rhizoma pinellinae praeparata, 8 parts of radix stemonae and 7 parts of fructus cannabis, the second component comprises 11 parts of lithospermum and 5 honeycomb parts, and the third component comprises 9 parts of pummelo peel.
The invention also provides a preparation method for treating cough and preventing haze,
mixing and crushing the first component, heating, mixing and steaming the heated first component and the second component, fermenting to obtain a first composition, soaking the first composition to obtain a first filtrate, extracting the first filtrate, and adding the third component extract.
Further, the heating treatment comprises cooking, the cooking time is 10-15 min, the fermentation comprises adding a leavening agent for fermentation, the extraction method of the first filtrate comprises reduced pressure evaporation to dryness, and the extraction method of the third component is water extraction.
Further, the reduced pressure evaporation drying condition is that the negative pressure is 0.08pa, and the temperature is 55-60 ℃.
The beneficial effect of above-mentioned scheme:
the anti-haze composition for treating cough provided by the invention is not limited to the product form, the raw material components are scientific and reasonable in proportion, and the components are synergistic, so that the anti-haze composition for preventing respiratory tract infection has an obvious effect on preventing the respiratory tract infection.
The anti-haze composition for preventing respiratory tract infection provided by the invention can prevent or reduce the harm of haze to the respiratory system of a human body, prevent harmful substances such as viruses, pollutants, bacteria and the like carried by particles in the haze, and prevent lung damage and function reduction caused by the haze.
The invention adopts the advanced technology, and optimizes and improves the traditional decoction process according to the property characteristics of the active ingredients of the raw material medicines. A great deal of experimental research has been conducted on the selection of the type and amount of enzyme. Finally obtaining the preparation method and the tablets prepared by the method. The method purifies the extract, and the obtained extract (extractum) is remarkably improved compared with the traditional method under the condition of reducing a large amount of impurities, the effective components are stable compared with the original traditional process, the curative effect is remarkably improved compared with the traditional process, and the production cost is greatly reduced.
Detailed Description
The present invention is described in further detail below with reference to specific embodiments.
A traditional Chinese medicine composition for treating cough and preventing haze comprises a first component, a second component and a third component, wherein the first component comprises:
12-16 parts of Chinese yam, 8-12 parts of angelica, 10-12 parts of salvia miltiorrhiza, 8-12 parts of radix ophiopogonis, 8-16 parts of houttuynia cordata, 8-12 parts of aster, 8-12 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 10-12 parts of lithospermum, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis; the second component comprises 5 honeycombs, and the third component comprises 7-11 parts of pummelo peel; wherein the parts are by weight.
The invention provides a traditional Chinese medicine composition for treating cough and preventing haze for people, which comprises the following steps:
mixing rhizoma Dioscoreae, radix Angelicae sinensis, Saviae Miltiorrhizae radix, radix Ophiopogonis, herba Houttuyniae, radix Asteris, flos Farfarae, fructus Trichosanthis, semen Armeniacae amarum, radix Codonopsis, rhizoma Pinelliae Preparata, radix Stemonae, and fructus Cannabis, crushing and pulverizing;
the mixture after the crushing is put into a steamer for heating treatment, wherein the heating treatment in the embodiment is steaming;
mixing and crushing lithospermum and honeycomb, putting into a steamer, steaming together until the mixture is cooled;
adding a leaven into the cooled composition for fermentation, and drying;
soaking the dried composition to obtain a filtrate;
extracting the filtrate to obtain extract;
adding exocarpium Citri Grandis extractive solution into the extract.
In the embodiment, the cooking time is 10-15 min, the fermentation comprises adding a leaven for fermentation, the extraction method of the filtrate comprises reduced pressure evaporation to dryness, and the pummelo peel extract is obtained by a water extraction method.
In the embodiment, the reduced pressure evaporation drying condition is that the negative pressure is 0.08pa, and the temperature is 55-60 ℃.
The following details are provided for the pharmacological actions of the Chinese herbs in the Chinese medicinal composition of the present invention:
chinese angelica: enrich the blood, promote blood circulation, moisten dryness and smooth intestines.
Red sage root: promoting blood circulation, dispelling blood stasis, clearing away heart-fire, relieving restlessness, cooling blood, and relieving carbuncle.
Radix ophiopogonis: moisten lung and clear heart, purge heat and promote fluid production, resolve phlegm and stop vomiting, cure cough and promote diuresis.
Houttuynia cordata: clearing away heat and toxic material, curing abscess and discharging pus, inducing diuresis and treating stranguria.
Radix asteris: warm lung, descend qi, resolve phlegm and relieve cough.
And (3) common coltsfoot flower: moisten lung and descend qi, resolve phlegm and stop cough.
And (3) snakegourd fruit: moisten lung, resolve phlegm, dissipate nodulation and smooth intestine.
Lithospermum: cool blood, activate blood, clear heat and remove toxicity, promote eruption.
Rhizoma pinelliae preparata: dry dampness and resolve phlegm.
Stemona root: moisten lung qi, dispel heat and release exterior.
The raw material medicaments are combined to treat cough and prevent the respiratory diseases of haze and hard qi, have extremely strong anti-inflammation and phlegm-reducing effects, and can quickly reduce phlegm and moisten lung. In addition, the traditional Chinese medicine composition provided by the embodiment is suitable for all ages, is not classified into men and women, and has an obvious effect after being used.
The following are specific preparation examples of the traditional Chinese medicine composition provided in this example:
example 1
Mixing and crushing 13 parts of Chinese yam, 9 parts of angelica, 10 parts of salvia miltiorrhiza, 9 parts of radix ophiopogonis, 10 parts of houttuynia cordata, 9 parts of aster, 9 parts of tussilago, 11 parts of trichosanthes kirilowii maxim, 8 parts of almond, 8 parts of codonopsis pilosula, 6 parts of rhizoma pinellinae praeparata, 6 parts of radix stemonae and 6 parts of fructus cannabis, and putting into a steamer for steaming for 10 minutes;
smashing 10 parts of lithospermum and 5 honeycomb, putting into a steamer, steaming and cooling the composition in the steamer;
adding a red yeast rice starter into the cooled composition for fermentation, wherein the addition amount of the red yeast rice starter is 1/4-1/3 of the weight of the cooled composition, the fermentation temperature is 36 ℃, and drying in the sun after the fermentation is finished;
soaking the dried composition in ethanol for 4 hr, filtering to remove residue to obtain filtrate, and evaporating the filtrate under reduced pressure at negative pressure of 0.08pa and temperature of 55 deg.C to obtain pasty plant extract;
extracting 8 parts of pummelo peel with water, and drying for later use;
dissolving exocarpium Citri Grandis in the pasty plant extract.
Example 2
The same method as that of example 1 is adopted, except that 15 parts of Chinese yam, 11 parts of angelica, 12 parts of salvia miltiorrhiza, 11 parts of ophiopogon root, 14 parts of houttuynia cordata, 11 parts of aster, 11 parts of tussilago farfara, 13 parts of trichosanthes kirilowii maxim, 10 parts of almond, 10 parts of codonopsis pilosula, 8 parts of rhizoma pinellinae praeparata, 9 parts of radix stemonae, 8 parts of fructus cannabis, 12 parts of lithospermum, 5 honeycomb parts of honey comb and 10 parts of pummelo peel;
the steaming time is 15min, and the temperature is 60 deg.C under reduced pressure.
Example 3
The same method as in example 1 was adopted, except that 14 parts of yam, 10 parts of angelica, 11 parts of salvia miltiorrhiza, 10 parts of ophiopogon root, 12 parts of houttuynia cordata, 10 parts of aster, 10 parts of tussilago farfara, 12 parts of trichosanthes kirilowii maxim, 9 parts of almond, 9 parts of codonopsis pilosula, 7 parts of rhizoma pinellinae praeparata, 8 parts of radix stemonae, 7 parts of fructus cannabis, 11 parts of lithospermum and 9 parts of pummelo peel;
steaming for 13min at 57 deg.C under reduced pressure
Comparative example 1
The clinical treatment effect of the traditional Chinese medicine composition for treating cough and preventing haze provided by the invention is as follows:
observing an object: one or more symptoms of red pharynx, tonsil swelling, rhinorrhea, cough, fever, etc. are selected as patients.
The anti-haze beverage disclosed in example 1 of chinese patent document CN105105235B is denoted as X1.
The Chinese medicinal formula similar to the Chinese medicinal composition in the embodiment 1 of the invention is marked as X2
The currently published cough treatment, anti-haze medication was purchased as X3.
The patients were divided into 8 groups of 500 patients, and were each administered the products of examples 1-3 of the present invention, and the products of comparative examples X1, X2, X3, wherein the products of examples 1-3, and X1, X2, X3 were administered daily for a week at a fixed dose.
The preventive effect is shown in table 1:
as can be seen from the above table, the product with anti-haze effect for preventing respiratory tract infection provided by the invention has obvious anti-haze effect for preventing respiratory tract infection, especially cough, and is superior to the pure traditional Chinese medicine composition X2, X1 and X3 in the same formula.
Comparative example 2
The following is a comparison of the effects of example 1, example 2 and example 3 in the clinical treatment effect of the traditional Chinese medicine composition for treating cough and preventing haze provided by the invention, and the comparison is directed to the people of different ages.
TABLE 2 preventive data on the effect of taking medicine at different ages
As can be seen from Table 2, the number of children who have developed the disease is not good enough to induce autoimmune diseases, but is poor in therapeutic effect because children are unwilling to take the medicine when the content of the medicine is increased.
The three drugs of example 1, example 2 and example 3 may be targeted to different populations.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. The traditional Chinese medicine composition for treating cough and preventing haze is characterized by comprising a first component, a second component and a third component, wherein the first component comprises:
12-16 parts of Chinese yam, 8-12 parts of angelica, 10-12 parts of salvia miltiorrhiza, 8-12 parts of radix ophiopogonis, 8-16 parts of houttuynia cordata, 8-12 parts of aster, 8-12 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis.
2. The traditional Chinese medicine composition for treating cough and preventing haze as claimed in claim 1, wherein the second component comprises 5 honeycomb and 10-12 parts of lithospermum, and the third component comprises 7-11 parts of pummelo peel.
3. The traditional Chinese medicine composition for treating cough and preventing haze as claimed in claim 2, wherein the first component comprises 12-15 parts of Chinese yam, 8-11 parts of angelica sinensis, 10-12 parts of salvia miltiorrhiza, 8-11 parts of radix ophiopogonis, 8-14 parts of houttuynia cordata, 8-11 parts of radix asteris, 8-11 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis; the second component comprises 10-12 parts of lithospermum and 5 honeycombs; the third component comprises 7-10 parts of pummelo peel.
4. The traditional Chinese medicine composition for treating cough and preventing haze as claimed in claim 3, wherein the first component comprises 13-15 parts of Chinese yam, 9-11 parts of angelica sinensis, 10-12 parts of salvia miltiorrhiza, 9-11 parts of radix ophiopogonis, 10-14 parts of houttuynia cordata, 9-11 parts of radix asteris, 9-11 parts of tussilago farfara, 11-13 parts of trichosanthes kirilowii maxim, 8-10 parts of almond, 8-10 parts of codonopsis pilosula, 6-8 parts of rhizoma pinellinae praeparata, 6-9 parts of radix stemonae and 6-8 parts of fructus cannabis; the second component comprises 10-12 parts of lithospermum and 5 honeycombs; the third component comprises 8-10 parts of pummelo peel.
5. The traditional Chinese medicine composition for treating cough and preventing haze according to claim 3, wherein the first component comprises 13 parts of Chinese yam, 9 parts of angelica sinensis, 10 parts of salvia miltiorrhiza, 9 parts of radix ophiopogonis, 10 parts of houttuynia cordata, 9 parts of aster, 9 parts of tussilago farfara, 11 parts of trichosanthes kirilowii maxim, 8 parts of almond, 8 parts of codonopsis pilosula, 6 parts of rhizoma pinellinae praeparata, 6 parts of radix stemonae and 6 parts of fructus cannabis; the second component comprises 10 parts of lithospermum and 5 honeycombs; the third component comprises 8 parts of pummelo peel.
6. The traditional Chinese medicine composition for treating cough and preventing haze according to claim 3, wherein the first component comprises 15 parts of Chinese yam, 11 parts of Chinese angelica, 12 parts of salvia miltiorrhiza, 11 parts of dwarf lilyturf tuber, 14 parts of houttuynia cordata, 11 parts of aster, 11 parts of tussilago farfara, 13 parts of snakegourd fruit, 10 parts of almond, 10 parts of codonopsis pilosula, 8 parts of rhizoma pinellinae praeparata, 9 parts of radix stemonae and 8 parts of fructus cannabis; the second component comprises 12 parts of lithospermum and 5 honeycombs; the third component comprises 10 parts of pummelo peel.
7. The traditional Chinese medicine composition for treating cough and preventing haze according to claim 3, wherein the first component comprises 145 parts of Chinese yam, 10 parts of angelica sinensis, 11 parts of salvia miltiorrhiza, 10 parts of ophiopogon root, 12 parts of houttuynia cordata, 10 parts of aster, 10 parts of tussilago farfara, 12 parts of trichosanthes kirilowii maxim, 9 parts of almond, 9 parts of codonopsis pilosula, 7 parts of rhizoma pinellinae praeparata, 8 parts of radix stemonae and 7 parts of fructus cannabis; the second part comprises 11 parts of lithospermum and 5 honeycombs; the third component comprises 9 parts of pummelo peel.
8. A preparation method of the traditional Chinese medicine composition for treating cough and preventing haze as claimed in any one of claims 1 to 7, characterized by mixing and crushing the first component, heating, mixing and steaming the heated first component and the second component, fermenting to obtain the first composition, soaking the first composition to obtain a first filtrate, extracting the first filtrate, and adding the third component extract.
9. The preparation method of the traditional Chinese medicine composition for treating cough and preventing haze as claimed in claim 8, wherein the heating treatment comprises steaming for 10-15 min; the fermentation comprises adding a fermentation agent for fermentation; the extraction method of the first filtrate comprises reduced pressure evaporation to dryness; the third component extraction method is water extraction.
10. The preparation method of the traditional Chinese medicine composition for treating cough and preventing haze according to claim 9, wherein the reduced-pressure evaporation-to-dryness condition is negative pressure of 0.08pa and temperature of 55-60 ℃.
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Application publication date: 20201211 |