CN112004925B - 具有降低的肝向性的AAV9和AAVrh74的杂合重组腺相关病毒血清型 - Google Patents

具有降低的肝向性的AAV9和AAVrh74的杂合重组腺相关病毒血清型 Download PDF

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CN112004925B
CN112004925B CN201980023352.XA CN201980023352A CN112004925B CN 112004925 B CN112004925 B CN 112004925B CN 201980023352 A CN201980023352 A CN 201980023352A CN 112004925 B CN112004925 B CN 112004925B
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aav
gene
aav9
hybrid
capsid
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CN112004925A (zh
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I·里夏尔
E·吉凯尔
F·明戈齐
G·龙齐蒂
P·维达尔
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Evry Wald Esson University
Institut National de la Sante et de la Recherche Medicale INSERM
Genethon
Association Institut de Myologie
Sorbonne Universite
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Evry Wald Esson University
Institut National de la Sante et de la Recherche Medicale INSERM
Genethon
Association Institut de Myologie
Sorbonne Universite
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CN201980023352.XA 2018-04-05 2019-04-04 具有降低的肝向性的AAV9和AAVrh74的杂合重组腺相关病毒血清型 Active CN112004925B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18305399.0 2018-04-05
EP18305399 2018-04-05
PCT/EP2019/058560 WO2019193119A1 (en) 2018-04-05 2019-04-04 HYBRID RECOMBINANT ADENO-ASSOCIATED VIRUS SEROTYPE BETWEEN AAV9 AND AAVrh74 WITH REDUCED LIVER TROPISM

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CN112004925A CN112004925A (zh) 2020-11-27
CN112004925B true CN112004925B (zh) 2024-09-27

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CN201980095204.9A Pending CN113795574A (zh) 2018-04-05 2019-10-04 具有降低的肝向性和增加的肌肉转导的AAV9和AAVrh74之间的肽修饰的杂合重组腺相关病毒血清型

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US (3) US12037362B2 (https=)
EP (2) EP3775173A1 (https=)
JP (2) JP7374119B2 (https=)
KR (2) KR20210015770A (https=)
CN (2) CN112004925B (https=)
AU (2) AU2019249890B2 (https=)
BR (2) BR112020020223A2 (https=)
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