CN1120000C - 刺激阴道革兰氏阳性杆菌生长、增强阴道酸度的药剂和其用途 - Google Patents
刺激阴道革兰氏阳性杆菌生长、增强阴道酸度的药剂和其用途 Download PDFInfo
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- CN1120000C CN1120000C CN98809507A CN98809507A CN1120000C CN 1120000 C CN1120000 C CN 1120000C CN 98809507 A CN98809507 A CN 98809507A CN 98809507 A CN98809507 A CN 98809507A CN 1120000 C CN1120000 C CN 1120000C
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- positive bacillus
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- 230000000813 microbial effect Effects 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 230000002969 morbid Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- WTEVQBCEXWBHNA-YFHOEESVSA-N neral Chemical compound CC(C)=CCC\C(C)=C/C=O WTEVQBCEXWBHNA-YFHOEESVSA-N 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 208000010484 vulvovaginitis Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims (24)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97122790.X | 1997-11-24 | ||
CN97122790 | 1997-11-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1271290A CN1271290A (zh) | 2000-10-25 |
CN1120000C true CN1120000C (zh) | 2003-09-03 |
Family
ID=5176887
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98809508A Expired - Fee Related CN1120001C (zh) | 1997-11-24 | 1998-11-24 | 刺激阴道革兰氏阳性杆菌生长、增强阴道酸度的药剂和其用途 |
CN98809507A Expired - Fee Related CN1120000C (zh) | 1997-11-24 | 1998-11-24 | 刺激阴道革兰氏阳性杆菌生长、增强阴道酸度的药剂和其用途 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN98809508A Expired - Fee Related CN1120001C (zh) | 1997-11-24 | 1998-11-24 | 刺激阴道革兰氏阳性杆菌生长、增强阴道酸度的药剂和其用途 |
Country Status (7)
Country | Link |
---|---|
US (2) | US6440949B1 (zh) |
EP (2) | EP1072269B1 (zh) |
CN (2) | CN1120001C (zh) |
AT (2) | ATE304362T1 (zh) |
AU (2) | AU1223199A (zh) |
DE (2) | DE69831609T2 (zh) |
WO (2) | WO1999026635A1 (zh) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
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IT1306141B1 (it) * | 1999-05-17 | 2001-05-30 | Giampiero Valletta | Composizione per il trattamento del prurito uremico e di forme diprurito non riconducibili a lesioni organiche. |
US6964949B2 (en) * | 2000-05-24 | 2005-11-15 | Shanghai Jiao Da Onlly Co., Ltd. | Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof |
JP2002113041A (ja) * | 2000-10-11 | 2002-04-16 | Uni Charm Corp | 皮膚常在菌をコントロールする吸収性物品 |
US20030017207A1 (en) * | 2001-05-01 | 2003-01-23 | Lin Shun Y. | Compositions and methods for treating vulvovaginitis and vaginosis |
NZ515869A (en) | 2001-11-30 | 2003-09-26 | Med Chem Ingredients Ltd | Compositions and methods for animal treatment comprising gluco- and isomalto- oligosaccharides |
US6589216B1 (en) | 2002-02-20 | 2003-07-08 | Abbott Research Group, Inc. | Vaginal douches, vaginal douche applicators and methods of vaginal douching |
US8118789B2 (en) | 2002-02-20 | 2012-02-21 | Abbott Research Group, Inc. | Deodorizer devices and systems for controlling perspiration-related body odor |
US7270653B2 (en) | 2002-02-20 | 2007-09-18 | Abbott Research Group | Methods of treating abnormal biological conditions using metal oxides |
US20040126369A1 (en) * | 2002-12-30 | 2004-07-01 | Richard Payne | Delivery of peroxide-generating enzymes to the vaginal tract |
US9241997B2 (en) * | 2003-06-13 | 2016-01-26 | Idh Holding Aps | Treatment of symptoms associated with bacterial vaginosis |
US8309103B2 (en) * | 2004-01-22 | 2012-11-13 | Alparis, S.A. De C.V. | Association of fluconazole-tinidazole for the treatment of vaginal infections, its composition, preparation process and usage |
US7276486B2 (en) * | 2004-03-15 | 2007-10-02 | Kimberly-Clark Worldwide, Inc. | Compositions for vaginal treatment |
US20050244402A1 (en) * | 2004-04-30 | 2005-11-03 | Villanueva Julie M | Absorption of pain-causing agents |
US20060093675A1 (en) * | 2004-10-29 | 2006-05-04 | Mathew Ebmeier | Intravaginal treatment of vaginal infections with metronidazole compositions |
US7619008B2 (en) * | 2004-11-12 | 2009-11-17 | Kimberly-Clark Worldwide, Inc. | Xylitol for treatment of vaginal infections |
US20060217443A1 (en) * | 2005-03-28 | 2006-09-28 | Kimberly-Clark Worldwide, Inc. | Method for preventing and/or treating vaginal and vulval infections |
US20060223765A1 (en) * | 2005-03-30 | 2006-10-05 | Kimberly-Clark Worldwide, Inc. | Method for inhibiting and/or treating vaginal infection |
CA2609754C (en) * | 2005-04-27 | 2012-01-10 | Shenzhen Phlora Biotechnology Limited | Compositions of benzoic acid and saccharides for regulating and maintaining bacterial flora and acidity in the vagina |
US7786176B2 (en) | 2005-07-29 | 2010-08-31 | Kimberly-Clark Worldwide, Inc. | Vaginal treatment composition containing xylitol |
US7801502B2 (en) * | 2006-12-18 | 2010-09-21 | Aai Corporation | Method for implementing continuous radio frequency (RF) alignment in advanced electronic warfare (EW) signal stimulation systems |
BRPI1006902A2 (pt) | 2009-01-23 | 2016-02-16 | Aziende Chimiche Riunte Angelini Francesco A C R A F S P A | formulação farmacêutica ou alimentícia de liberação controlada, processo para a produção de uma forma farmacêutica ou alimentícia, sistema de liberação controlada, e, uso de um sistema de liberação controlada |
KR101133723B1 (ko) * | 2009-10-19 | 2012-04-09 | 최원석 | 소금 및 당을 유효성분으로 함유하는 질염 예방 및 치료용 조성물 및 이의 용도 |
US8409628B2 (en) | 2010-02-04 | 2013-04-02 | Penguin IP Holdings, Inc. | Methods and compositions for oxygenation of skin to treat skin disorders |
EP2489408A1 (de) | 2011-01-13 | 2012-08-22 | Michael Tchirikov | Aminosäurezusammensetzung und deren Verwendung zur Behandlung von fetaler Wachstumsrestriktion (IUGR) und zur parenteralen Ernährung von extrem Frühgeborenen |
CN103110973A (zh) * | 2013-01-24 | 2013-05-22 | 量子高科(中国)生物股份有限公司 | 保护生殖道微生态健康平衡的方法 |
EP3117827B1 (en) * | 2014-03-13 | 2021-11-03 | Singapore Ze&Z International Pte. Ltd. | Composition for vagina and use of the composition |
CN104825946A (zh) * | 2015-04-10 | 2015-08-12 | 付秀花 | 一种洁阴洗液及其制备方法 |
PL3324938T3 (pl) * | 2015-07-20 | 2022-01-10 | Trilogic Pharma Llc | Preparaty do stosowania miejscowego i sposoby leczenia |
AU2015410635B2 (en) | 2015-09-29 | 2021-08-19 | Kimberly-Clark Worldwide, Inc. | Synergistic composition for maintenance of healthy balance of microflora |
EP3442501A1 (en) | 2016-04-15 | 2019-02-20 | Fairhaven Health, LLC | Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract |
CN109771434A (zh) * | 2019-03-07 | 2019-05-21 | 江西鼎中科技有限公司 | 一种治疗阴道炎的蔗糖和低聚木糖凝胶 |
GB202018068D0 (en) | 2020-11-17 | 2020-12-30 | Ucl Business Ltd | Pharmaceutical composition |
CN112451472A (zh) * | 2020-11-27 | 2021-03-09 | 江苏威克斯医疗科技有限公司 | 一种调节阴道微生态的组合物及其制备方法 |
EP4324465A1 (en) * | 2022-08-15 | 2024-02-21 | Gedea Biotech AB | Compounds for use in the treatment of a microbial infection in the urogenital system |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1390803A (en) * | 1972-07-18 | 1975-04-16 | Wootton L W | Medicinal tampons and compositions containing lactulose |
IT1172185B (it) * | 1981-12-21 | 1987-06-18 | Serono Ist Farm | Composizione particolarmente per la vande vaginali |
EP0190770B1 (en) * | 1985-02-08 | 1992-10-07 | Daicel Chemical Industries, Ltd. | Fermentation to d-lactic acid |
JPS61227777A (ja) * | 1985-04-02 | 1986-10-09 | Showa Sangyo Kk | ビフイズス菌生育活性剤 |
US5266329A (en) * | 1985-10-31 | 1993-11-30 | Kv Pharmaceutical Company | Vaginal delivery system |
SE8603338D0 (sv) * | 1986-08-07 | 1986-08-07 | Bjorn Andersch | Medel for behandling av tillstand i slidan |
US4837154A (en) * | 1987-01-14 | 1989-06-06 | Wisconsin Alumni Research Foundation | Selective growth medium for isolation of Mobiluncus from vaginal fluid |
DK505488D0 (da) * | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
US5211971A (en) * | 1989-10-23 | 1993-05-18 | Unilever Patent Holdings B.V. | Lactic acid bacteria cultures supported on an expanded cereal for preparing flavor or aroma material |
ATE214592T1 (de) * | 1990-12-21 | 2002-04-15 | Felice Bombart | Wässrige vaginaldusche und deren anwendung |
US5573765A (en) * | 1991-02-19 | 1996-11-12 | Mark S. Reinhard | Composition and method for treatment of vaginal yeast infections |
FR2678166B1 (fr) * | 1991-06-27 | 1993-10-22 | Bioeurope | Compositions cosmetiques contenant des glucooligosaccharides. |
SE9200199L (sv) * | 1992-01-24 | 1993-07-25 | Rune Soeremark | Farmaceutisk komposition och dess anvaendning |
HU212426B (en) * | 1992-07-22 | 1996-06-28 | Vepex Kft | Process for producing bioactive pharmaceutical compositions |
IT1255488B (it) * | 1992-08-04 | 1995-11-06 | Angelini Francesco Ist Ricerca | Polisaccaridi del glicogeno |
CN1039087C (zh) * | 1993-12-29 | 1998-07-15 | 昆明宏达实业有限总公司 | 妇科病治疗保健外用药物 |
DE19503423A1 (de) * | 1995-02-03 | 1996-08-08 | Beiersdorf Ag | Antiadhäsive Wirkstoffe |
AU1854297A (en) * | 1996-02-14 | 1997-09-02 | Procter & Gamble Company, The | Urogenital and intestinal disorder compositions comprising substance derived from plant species of the ericaceae family and a lactic acid bacteria growth factor |
US6165997A (en) * | 1997-11-20 | 2000-12-26 | Statens Serum Institut | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
-
1998
- 1998-11-24 CN CN98809508A patent/CN1120001C/zh not_active Expired - Fee Related
- 1998-11-24 AU AU12231/99A patent/AU1223199A/en not_active Abandoned
- 1998-11-24 WO PCT/CN1998/000277 patent/WO1999026635A1/zh active IP Right Grant
- 1998-11-24 DE DE69831609T patent/DE69831609T2/de not_active Expired - Lifetime
- 1998-11-24 AT AT98955312T patent/ATE304362T1/de not_active IP Right Cessation
- 1998-11-24 CN CN98809507A patent/CN1120000C/zh not_active Expired - Fee Related
- 1998-11-24 AU AU12230/99A patent/AU1223099A/en not_active Abandoned
- 1998-11-24 EP EP98955313A patent/EP1072269B1/en not_active Expired - Lifetime
- 1998-11-24 DE DE69831878T patent/DE69831878D1/de not_active Expired - Fee Related
- 1998-11-24 WO PCT/CN1998/000278 patent/WO1999026636A1/zh active IP Right Grant
- 1998-11-24 EP EP98955312A patent/EP1072268B1/en not_active Expired - Lifetime
- 1998-11-24 AT AT98955313T patent/ATE306274T1/de not_active IP Right Cessation
-
2000
- 2000-05-24 US US09/578,177 patent/US6440949B1/en not_active Expired - Fee Related
- 2000-05-24 US US09/577,858 patent/US6632796B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6440949B1 (en) | 2002-08-27 |
EP1072269A1 (en) | 2001-01-31 |
DE69831609D1 (de) | 2005-10-20 |
DE69831609T2 (de) | 2006-02-02 |
CN1120001C (zh) | 2003-09-03 |
AU1223199A (en) | 1999-06-15 |
ATE304362T1 (de) | 2005-09-15 |
CN1271291A (zh) | 2000-10-25 |
EP1072269B1 (en) | 2005-10-12 |
US6632796B1 (en) | 2003-10-14 |
WO1999026636A1 (fr) | 1999-06-03 |
ATE306274T1 (de) | 2005-10-15 |
EP1072268B1 (en) | 2005-09-14 |
CN1271290A (zh) | 2000-10-25 |
EP1072268A4 (en) | 2003-09-03 |
AU1223099A (en) | 1999-06-15 |
EP1072268A1 (en) | 2001-01-31 |
EP1072269A4 (en) | 2003-08-27 |
WO1999026635A1 (fr) | 1999-06-03 |
DE69831878D1 (de) | 2006-02-23 |
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Owner name: SHENZHEN FUNUO BIOLOGICAL TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: CENG ZHONGMING Effective date: 20120105 |
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Effective date of registration: 20120105 Address after: 518052 Shenzhen Nanshan District City, Ma Liuzhou Industrial Zone 69 floor Patentee after: Shenzhen Funuo Biological Technology Co., Ltd. Address before: Nanshan District people's Hospital of Shenzhen, Guangdong, Nantou Patentee before: Zeng Zhongming |
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Denomination of invention: Pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in vagina and use thereof Effective date of registration: 20120613 Granted publication date: 20030903 Pledgee: Xinjiang bioco Vinda Tianshan equity investment limited partnership Pledgor: Shenzhen Funuo Biological Technology Co., Ltd. Registration number: 2012990000294 |
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