CN111888445A - Preparation process of traditional Chinese medicine pills for treating urinary calculus - Google Patents

Preparation process of traditional Chinese medicine pills for treating urinary calculus Download PDF

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CN111888445A
CN111888445A CN202010921726.4A CN202010921726A CN111888445A CN 111888445 A CN111888445 A CN 111888445A CN 202010921726 A CN202010921726 A CN 202010921726A CN 111888445 A CN111888445 A CN 111888445A
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pill
parts
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bin
reduction gear
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潘晶
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12Magnesium silicate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/10Peat; Amber; Turf; Humus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
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    • A61K36/076Poria
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/60Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
    • B01F27/72Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis with helices or sections of helices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/22Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention discloses a preparation process of traditional Chinese medicine pills for treating urinary calculus, which comprises the steps of crushing Japanese climbing fern spore, endothelium corneum gigeriae galli, rhizoma alismatis, agilawood, amber, semen plantaginis, radix curcumae, poria cocos, platycodon grandiflorum and radix cyathulae, sieving to obtain mixed medicine powder, mixing earthworm, scouring rush, cluster mallow seed and liquorice, adding water, decocting for three times, mixing decoction, filtering to obtain filtrate, cooling the filtrate, adding potassium nitrate, stirring uniformly, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain concentrated solution, putting the mixed medicine powder, talcum powder, cane sugar and the concentrated solution into pill production equipment, mixing uniformly, and preparing into pills to obtain the traditional Chinese medicine pills for treating urinary calculus; the traditional Chinese medicine pill is prepared by matching sixteen Chinese herbal medicines with cane sugar, treats urinary calculus by utilizing the comprehensive synergistic effect of the sixteen Chinese herbal medicines, has small side effect on human body, does not need decoction of patients, and has the characteristics of simple and convenient treatment method, low price, remarkable curative effect and no pain feeling in the treatment process.

Description

Preparation process of traditional Chinese medicine pills for treating urinary calculus
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a preparation process of traditional Chinese medicine pills for treating urinary calculus.
Background
The urinary calculus is a general term of calculus diseases of all parts of the urinary system, is a common disease of the urinary system, and comprises kidney calculus, ureteral calculus, vesical calculus and urethral calculus, and is called as damp-heat accumulation and qi deficiency and blood stasis disease in traditional Chinese medicine, and typical sudden renal or ureteral colic accompanied by macroscopic or microscopic hematuria seriously affects the body health of people. Its onset is often related to various factors such as metabolism, diet, environment and urinary system diseases.
At present, the urinary calculus is treated on the basis of the principles of spasmolysis and pain relief, calculus removal, renal function maintenance and relapse prevention, and the sizes, the parts, the number, complications and the general conditions of the calculus are treated by operation treatment and drug treatment as treatment means, so that the existing drug treatment has the problems of slow effect taking, unsatisfactory curative effect and long treatment course, and the operation treatment has the problems of high cost and pain of patients.
Therefore, how to improve the problems of slow response, poor treatment effect, long treatment course, high operation treatment cost and pain of patients existing in the prior urinary calculus medicament treatment is the problem to be solved by the invention.
Disclosure of Invention
In order to overcome the technical problems, the invention aims to provide a preparation process of a traditional Chinese medicine pill for treating urinary calculus, which comprises the following steps: crushing lygodium japonicum, endothelium corneum gigeriae galli, rhizoma alismatis, agilawood, amber, semen plantaginis, radix curcumae, poria cocos, platycodon grandiflorum and radix cyathulae, sieving the crushed lygodium japonicum, endothelium corneum gigeriae galli, rhizoma alismatis, agilawood, amber, semen plantaginis, radix curcumae, poria cocos, platycodon grandiflorum and radix cyathulae with a 100-mesh sieve to obtain mixed medicinal powder, mixing earthworm, scouring rush, chingma abutilon seed and liquorice, adding water, decocting for three times, mixing decoction solutions, filtering to obtain a filtrate, cooling the filtrate, adding potassium nitrate, uniformly stirring, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain a concentrated solution, pouring the mixed medicinal powder, talcum powder, cane sugar and the concentrated solution into a feed hopper, then putting the feed into a shearing cylinder, shearing the mixed medicinal powder, talcum powder, cane sugar and the concentrated solution through a rotating thread shearing rod to obtain mixed raw, Make its shaping, the universal driving shaft and cutting knife have been realized in the operation of pelletization motor, the columniform mixed raw materials is cut into the graininess to the pivoted cutting knife, fall into and connect a fill, pill motor operation has realized the carousel and has rotated, the graininess mixed raw materials gets into in the pill storehouse from connecing a fill bottom, along with the carousel rotates, the graininess mixed raw materials rolls and forms the pill form, collect and obtain this a traditional Chinese medicine pellet for treating urinary calculus after the drying, it is slow to have the effect in current urinary calculus drug therapy to have solved, the curative effect is poor, long treatment, the operation treatment expense is high, the painful problem of patient.
The purpose of the invention can be realized by the following technical scheme:
a preparation process of traditional Chinese medicine pills for treating urinary calculus comprises the following steps:
the method comprises the following steps: pulverizing spora Lygodii, endothelium corneum Gigeriae Galli, Alismatis rhizoma, lignum Aquilariae Resinatum, Succinum, semen plantaginis, radix Curcumae, Poria, radix Platycodi, and radix Cyathulae, and sieving with 100 mesh sieve to obtain mixed medicinal powder;
step two: mixing earthworm, scouring rush, cluster mallow seed and liquorice, adding 8-10 times of water by weight, decocting for 1.2 hours after the water is boiled to obtain a first decoction, adding 6-8 times of water by weight after the first decoction is poured out, decocting for 1 hour after the water is boiled to obtain a second decoction, adding 4-6 times of water by weight after the second decoction is poured out, decocting for 1 hour after the water is boiled to obtain a third decoction, combining the first decoction, the second decoction and the third decoction, and filtering to obtain a filtrate;
step three: adding the potassium nitrate into the cooled filtrate, uniformly stirring, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain concentrated solution, starting a power mechanism of pill production equipment, rotating a driving shaft by the operation of a driving motor, so as to drive a thread shearing rod of a mixing extrusion mechanism to rotate, pouring mixed medicinal powder, talcum powder, cane sugar and concentrated solution into a feed hopper, feeding the mixed medicinal powder, the talcum powder, the cane sugar and the concentrated solution into a shearing cylinder from the bottom of the feed hopper, shearing the mixed medicinal powder, the talcum powder, the cane sugar and the concentrated solution by the rotating thread shearing rod, uniformly mixing to obtain mixed raw materials, conveying the mixed raw materials forward by the rotating thread shearing rod to enter an extrusion die head, making the mixed raw materials into a cylindrical shape by the extrusion die head, starting a granulating motor and a second electric heating fan of the granulating mechanism, releasing hot air by the second electric heating fan to dry the cylindrical mixed raw materials to, Make its shaping, the universal driving shaft and cutting knife have been realized in the operation of pelletization motor and have been rotated, the columniform mixed raw materials is cut into the graininess to the pivoted cutting knife, fall into and connect a fill, start the pill motor of pill mechanism, the operation of pill motor has realized the carousel and has rotated, the graininess is mixed the raw materials and is followed and connect a fill bottom and get into in the pill storehouse, fall to the inner chamber edge of pivoted carousel, along with the carousel rotates, roll in its inside, roll the graininess and mix the raw materials and form the pill form, collect and obtain this a traditional Chinese medicine pellet for treating urinary calculus after the drying.
As a further scheme of the invention: the traditional Chinese medicine pill for treating urinary calculus is prepared from the following components in parts by weight:
4-8 parts of lygodium japonicum, 2-6 parts of endothelium corneum gigeriae galli, 4-8 parts of rhizoma alismatis, 4-8 parts of lumbricus, 1-3 parts of agilawood, 1-3 parts of amber, 2-6 parts of potassium nitrate, 4-8 parts of scouring rush, 8-12 parts of cluster mallow fruit, 4-8 parts of semen plantaginis, 4-8 parts of radix curcumae, 4-8 parts of poria cocos, 15-19 parts of talcum powder, 2-7 parts of liquorice, 4-8 parts of platycodon grandiflorum, 4-8 parts of medicinal cyathula root and 8-12 parts of cane sugar.
As a further scheme of the invention: the power mechanism comprises a driving motor, a first supporting base and a reduction gearbox, the reduction gearbox is mounted at the top of the first supporting base, a driven belt pulley is mounted on one side of the reduction gearbox through a rotating shaft, the driven belt pulley is connected with a driving belt pulley through a belt, and the driving belt pulley is sleeved on an output shaft of the driving motor; the reduction gearbox is characterized in that a first reduction gear, a second reduction gear, a third reduction gear and a fourth reduction gear are installed in the inner cavity of the reduction gearbox, the driven belt pulley is connected to the first reduction gear through a rotating shaft, the first reduction gear is connected with the second reduction gear in a meshed mode, the third reduction gear is welded at one end of the second reduction gear, the second reduction gear and the third reduction gear are installed to the inner cavity of the reduction gearbox through the rotating shaft, the third reduction gear is connected with the fourth reduction gear in a meshed mode, and the fourth reduction gear is sleeved on one end of the transmission shaft.
As a further scheme of the invention: the compounding extruding mechanism includes feeder hopper, blending bunker, second support base, extrusion die head, the feeder hopper is installed in blending bunker top one end, the blending bunker is installed in the bottom that the base was supported to the second, install the first electric heat fan of a shearing section of thick bamboo and a plurality of in the blending bunker inner chamber, shearing section of thick bamboo inner chamber bottom and the first electric heat fan intercommunication of a plurality of, shearing section of thick bamboo one end top and feeder hopper bottom intercommunication, the shearing section of thick bamboo is kept away from feeder hopper one end and is installed extrusion die head, installs the screw thread shearing bar in the shearing section of thick bamboo inner chamber.
As a further scheme of the invention: the pelletization mechanism includes granulation storehouse, pelletization motor, connects a fill, second electric fan, it installs the pelletization motor to run through on the granulation storehouse side, granulation storehouse bottom is installed and is connect a fill, granulation storehouse one side communicates to second electric fan through the pipeline, it installs the universal driving shaft to rotate through the bearing on the vertical center line in granulation storehouse side, driven gear has been cup jointed on the universal driving shaft, the driving gear has been cup jointed on the output shaft of pelletization motor, the driving gear is connected with driven gear meshing, driven gear one end is cup jointed and is installed the cutting knife to the universal driving shaft is kept away from.
As a further scheme of the invention: pill mechanism is including pill storehouse, row's material fill, pellet bin, motor case, install the pellet bin in pill storehouse bottom inner chamber, pellet bin top communicates to row's bottom of fighting, row's material fill runs through the installation on pill storehouse, pill storehouse bottom is equipped with the motor case in pellet bin one side, rotate through the bearing in pill storehouse top inner chamber and install the carousel, the rodent has been seted up on the carousel side, carousel one side meshing is connected with drive gear, drive gear cup joints on the output shaft of pill motor, the pill motor is installed in motor case inner chamber.
As a further scheme of the invention: the pill production equipment in the third step produces the traditional Chinese medicine pills for treating the urinary calculus in the following working process:
the method comprises the following steps: starting a driving motor of the power mechanism, wherein the driving motor drives a first reduction gear to rotate through a driving belt pulley and a driven belt pulley, so that a second reduction gear, a third reduction gear, a fourth reduction gear and a transmission shaft are sequentially driven to rotate, and a thread shearing rod of the mixing extrusion mechanism is driven to rotate;
step two: pouring the mixed medicinal powder, the talcum powder, the sucrose and the concentrated solution into a feed hopper of a mixing and extruding mechanism, feeding the mixed medicinal powder, the talcum powder, the sucrose and the concentrated solution into a shearing barrel from the bottom of the feed hopper, shearing the mixed medicinal powder, the talcum powder, the sucrose and the concentrated solution through a rotating threaded shearing rod, uniformly mixing to obtain a mixed raw material, conveying the mixed raw material forwards through the rotating threaded shearing rod, feeding the mixed raw material into an extruding die head, and making the mixed raw material into a cylinder shape through the extruding die head;
step three: starting a granulating motor and a second electric heating fan of the granulating mechanism, wherein the second electric heating fan releases hot air to dry and form the cylindrical mixed raw material to a certain extent, the granulating motor drives a linkage shaft and a cutting knife to rotate through a driving gear and a driven gear, and the rotating cutting knife cuts the cylindrical mixed raw material into particles and falls into a particle receiving hopper;
step four: starting a pelleting motor of the pelleting mechanism, wherein the pelleting motor operates to drive a transmission gear to rotate so as to drive a rotary table to rotate, and granular mixed raw materials enter a pelleting bin from the bottom of a pelleting hopper, fall to the edge of an inner cavity of the rotating rotary table, roll in the rotating rotary table along with the rotation of the rotary table and roll in the rotating rotary table to form pills;
step five: stopping the rotation of the turntable, enabling the pill-shaped mixed raw materials to roll towards the circle center of the turntable, discharging the mixture from the circle center of the turntable to a pill storage box through a discharge hopper for storage, and drying to obtain the traditional Chinese medicine pill for treating the urinary calculus.
As a further scheme of the invention: the formula of the traditional Chinese medicine pill for treating the urinary calculus comprises the following components:
climbing fern spore: [ PROPERTIES AND FLAVOUR ] sweet, light, cold and nontoxic; [ GUIJING ] Small intestine, spleen, bladder meridian; [ FUNCTIONS ] can clear away heat and toxic materials, promote diuresis, and treat stranguria; treating heat stranguria, bloody stranguria, sand stranguria, whitish and turbid urine, leukorrhagia, edema due to dampness and heat, dysentery due to dampness and heat, jaundice due to dampness and heat, hematemesis, epistaxis, hematuria and traumatic hemorrhage.
Endothelium corneum gigeriae galli: [ PROPERTIES AND FLAVOUR ] sweet in taste and neutral in nature; [ GUIJING ] spleen, stomach, kidney, bladder channels; [ FUNCTIONS ] can invigorate spleen, promote digestion, arrest spontaneous emission, and eliminate symptoms and calculus; it is mainly used for treating dyspepsia, food stagnation, emesis, regurgitation, diarrhea, dysentery, infantile malnutrition, nocturnal emission, enuresis, frequent micturition, urinary calculus and gallstone, amenorrhea, pharyngitis, tonsillitis, and aphtha.
Rhizoma alismatis: [ PROPERTIES AND FLAVOUR ] sweet, bland and cold in nature; [ GUIJING ] enters kidney and bladder meridians; [ FUNCTIONS ] can promote diuresis, eliminate dampness, clear heat and treat stranguria; dysuria, heat stranguria, pain with astringents, edema, diarrhea, phlegm-fluid retention, vertigo and spermatorrhea.
Earthworm: [ PROPERTIES AND FLAVOUR ] salty in taste and cold in nature; [ GUIJING ] enters liver, spleen and bladder meridians; [ FUNCTIONS ] can clear heat and relieve spasm, calm liver to stop endogenous wind, dredge meridian passage, relieve asthma and induce diuresis; fever and mania due to major heat, convulsive epilepsy and convulsion, headache due to liver-yang, apoplexy and hemiplegia, rheumatic arthralgia, cough and asthma due to lung-heat, and difficulty in urination.
Agilawood: [ PROPERTIES AND WESTERN ] is pungent, bitter and warm; [ GUIJING ] Kidney, spleen, stomach, Mingmen, Lung, gallbladder, and liver meridians; [ FUNCTIONS ] can promote the circulation of qi to relieve pain, warm the middle-jiao to check adverse rise of qi, and absorb qi to relieve asthma; cold pain in the abdomen, dyspnea, vomiting, hiccup due to stomach cold, deficient cold in the waist and knees, deficient constipation of the large intestine, and stranguria due to urinary qi.
Amber: [ PROPERTIES AND FLAVOUR ] sweet, mild and nontoxic; [ GUIJING ] Heart, liver, small intestine, bladder, lung, spleen; [ FUNCTIONS INDICATIONS ] has effects of relieving convulsion, tranquilizing mind, removing blood stasis, stopping bleeding, promoting diuresis, treating stranguria, removing nebula, and improving eyesight; it is mainly indicated for pavor, insomnia, convulsions, epilepsy, stranguria with blood, hematuria, amenorrhea due to blood stagnation, postpartum abdominal pain due to stasis, abdominal mass, nebula, carbuncle, swelling and sore.
And (3) nitrate: [ PROPERTIES AND WESTERN ] is salty, warm and slightly toxic; [ FUNCTIONS AND INDICATIONS ] can kill parasites, remove calculus, and relieve stuffy tumor; can be used for treating stranguria caused by urinary stone, glomus tumor, diseases, and indigestion.
Scouring rush: [ PROPERTIES AND FLAVOUR ] is sweet, bitter, mild and nontoxic; [ GUIJING ] Lung, liver, gallbladder channel; [ FUNCTIONS ] can dispel pathogenic wind, clear heat, cool blood, stop bleeding, improve eyesight, and remove nebula; wind-heat affecting blood-shot eyes, nebula in eyes, tearing in the wind, bleeding due to intestinal wind, hemorrhoidal bleeding, bloody dysentery, women's continuous menstruation and rectocele.
Mallow seeds: [ PROPERTIES AND FLAVOUR ] sweet and cold; [ GUIJING ] large intestine, small intestine, liver, lung, stomach, bladder channels; [ FUNCTIONS ] has effects in promoting diuresis, treating stranguria, smoothing intestine, relieving constipation, and promoting lactation; it is mainly manifested as stranguria, edema, constipation and dysuria.
Plantain seed: [ PROPERTIES AND FLAVOUR ] sweet, bland and slightly cold in nature; [ GUIJING ] enters lung, liver, kidney and bladder meridians; [ FUNCTIONS ] can clear away heat, promote urination, eliminate dampness, stop diarrhea, improve eyesight, and eliminate phlegm; dysuria, stranguria with turbid discharge, edema, fullness and distention, summer-heat and dampness, dysentery, conjunctival congestion, nebula, phlegm-heat cough and asthma.
Turmeric root-tuber: [ PROPERTIES AND WESTERN ] is pungent, bitter and cold in flavor; [ GUIJING ] Heart, liver, gallbladder channel; [ FUNCTIONS ] has effects in promoting blood circulation, relieving energy, promoting circulation of qi, relieving qi stagnation, clearing away heart-fire, cooling blood, dispersing depressed liver-energy, and promoting function of gallbladder; pain in chest, abdomen and hypochondrium, dysmenorrhea, amenorrhea, lump in the abdomen, coma due to febrile disease, mania, epilepsy, hematemesis, epistaxis, stranguria with blood, sand stranguria, and jaundice.
Tuckahoe, poria cocos: [ PROPERTIES AND FLAVOUR ] sweet, light and mild; [ GUIJING ] channels the heart, spleen, lung and kidney channels; [ FUNCTIONS INDICATIONS ] has effects of eliminating dampness, promoting diuresis, invigorating spleen, regulating stomach function, calming heart, and tranquilizing mind; dysuria, edema, fullness and distention, phlegm-fluid, cough, vomiting, spleen deficiency, anorexia, diarrhea, palpitation, uneasiness, insomnia, amnesia, nocturnal emission, and whitish and turbid urine.
Talc powder: [ PROPERTIES AND FLAVOUR ] sweet, bland and cold; [ GUIJING ] enters bladder, lung and stomach meridians; [ FUNCTIONS ] has effects in promoting urination, relieving stranguria, clearing away summer-heat, eliminating dampness, and healing sore; can be used for treating pyretic stranguria, stranguria with stone, pyretic urine, odynuria, summer-heat dampness, polydipsia, damp-heat watery diarrhea, eczema, miliaria, etc.
Licorice root: [ PROPERTIES AND FLAVOUR ] sweet and neutral; [ GUIJING ] spleen, stomach, heart, and lung channels; [ FUNCTIONS INDICATIONS ] can tonify qi, strengthen the middle-jiao, relieve spasm and pain, moisten lung to arrest cough, purge fire and remove toxicity, and harmonize the drugs; it is mainly manifested as lassitude, poor appetite, emaciation, sallow complexion, palpitation, shortness of breath, abdominal pain, loose stool, spasm and pain of limbs, irritability, cough, asthma, sore throat, carbuncle, sore and swelling, infantile carbuncle, and drug and food poisoning.
Balloon flower: [ PROPERTIES AND WESTERN ] with bitter and pungent taste and mild property; [ GUIJING ] enters lung and stomach meridians; [ FUNCTIONS INDICATIONS ] can ventilate lung, dispel phlegm, relieve sore throat, and expel pus; cough with profuse sputum, swollen and sore throat, lung abscess with pus, hypochondriac pain, dysentery with abdominal pain, dysuria with dysuria.
Radix cyathulae: [ PROPERTIES AND WESTERN PROPERTIES ] is sweet, slightly bitter and neutral in nature; [ GUIJING ] liver and kidney meridians; [ FUNCTIONAL INDICATIONS ] has effects of promoting blood circulation, dispelling blood stasis, expelling pathogenic wind, and removing dampness; it is mainly indicated for amenorrhea due to blood stasis, dystocia, retained afterbirth, postpartum abdominal pain due to blood stasis, heat stranguria, stranguria with stone, dysmenorrhea, and rheumatic pain of waist and knees.
The invention has the beneficial effects that:
(1) the invention relates to a preparation process of a traditional Chinese medicine pill for treating urinary calculus, which comprises the steps of crushing lygodium japonicum, endothelium corneum gigeriae galli, rhizoma alismatis, agilawood, amber, semen plantaginis, radix curcumae, poria cocos, platycodon grandiflorum and radix cyathulae, sieving by a 100-mesh sieve to obtain mixed medicinal powder, mixing earthworm, scouring rush, cluster mallow fruit and liquorice, adding water, decocting for three times, mixing decoction, filtering to obtain filtrate, adding potassium nitrate after the filtrate is cooled, uniformly stirring, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain concentrated solution, uniformly mixing the mixed medicinal powder, talcum powder, cane sugar and the concentrated solution, and preparing into pills to obtain the traditional Chinese medicine pill for treating urinary calculus; the traditional Chinese medicine pill for treating the urinary calculus is prepared by matching sixteen Chinese herbal medicines with the sucrose, treats the urinary calculus by utilizing the comprehensive synergistic effect of the sixteen Chinese herbal medicines, has small side effect on a human body, does not need decoction of a patient, has the characteristics of simple and convenient treatment method, low price and obvious curative effect, has good effect on preventing and treating the urinary calculus, and has no pain feeling in the treatment process;
(2) the invention relates to a process for preparing traditional Chinese medicine pills for treating urinary calculus, which comprises the steps of preparing the traditional Chinese medicine pills for treating urinary calculus by utilizing pill production equipment, starting a power mechanism of the pill production equipment, driving a motor to operate to realize rotation of a transmission shaft, driving a thread shearing rod of a mixing extrusion mechanism to rotate, pouring mixed medicine powder, talcum powder, cane sugar and concentrated solution into a feed hopper, feeding the mixed medicine powder, the talcum powder, the cane sugar and the concentrated solution into a shearing cylinder from the bottom of the feed hopper, shearing the mixed medicine powder, the talcum powder, the cane sugar and the concentrated solution by the rotating thread shearing rod, uniformly mixing to obtain mixed raw materials, conveying the mixed raw materials forwards by the rotating thread shearing rod, feeding the mixed raw materials into an extrusion die head, making the mixed raw materials into a cylindrical shape by the extrusion die head, and starting a granulating motor and a second electric heating fan of a granulating, the second electric heating fan releases hot air to dry the cylindrical mixed raw materials to a certain degree and form the cylindrical mixed raw materials, the granulating motor operates to realize the rotation of the universal driving shaft and the cutting knife, the rotating cutting knife cuts the cylindrical mixed raw materials into particles and falls into the particle receiving hopper, the pill making motor of the pill making mechanism is started, the pill making motor operates to realize the rotation of the turntable, the granular mixed raw materials enter the pill making bin from the bottom of the particle receiving hopper and fall to the edge of the inner cavity of the rotating turntable, the granular mixed raw materials roll in the rotating turntable along with the rotation of the turntable to form pills, and the traditional Chinese medicine pills for treating urinary calculus are obtained after being dried; this pellet production facility will mix powder through pivoted screw thread shear bar, talcum powder, sucrose and concentrate misce bene, it is more abundant to make between the various raw materials, it is better to make the traditional chinese medicine pellet drug effect that is used for treating urinary calculus who makes, the quality is higher, the curative effect of product has been improved effectively, the dose of taking has been reduced, and this equipment extrudes mixed raw materials through compounding extrusion mechanism, the mixed raw materials branch that will extrude is cut into a plurality of particulate matter that the size is the same through pelletization mechanism, make a plurality of particulate matter roll through pill-making mechanism, form the pill form, the automatic production process of traditional chinese medicine pellet that is used for treating urinary calculus has been accomplished to this equipment, work efficiency is improved effectively, thereby the manufacturing cost of this traditional chinese medicine pellet that is used for treating urinary calculus has been reduced, patient's treatment expense has been reduced.
Drawings
The invention will be further described with reference to the accompanying drawings.
FIG. 1 is a schematic view of the construction of a pill producing apparatus according to the present invention;
FIG. 2 is a schematic connection diagram of a power mechanism and a mixing and extruding mechanism in the invention;
FIG. 3 is a schematic view of the internal structure of the reduction gearbox of the present invention;
FIG. 4 is a schematic view of the internal structure of the mixing silo of the present invention;
FIG. 5 is a schematic view of the construction of the threaded shear bar of the present invention;
FIG. 6 is a schematic view of the connection of the granulating mechanism and the pelletizing mechanism of the present invention;
FIG. 7 is a schematic view of the connection of the driving gear and the driven gear of the present invention;
FIG. 8 is a front view of the cutting blade of the present invention;
FIG. 9 is a schematic view of the internal structure of the pelletizing mechanism of the invention.
In the figure: 100. a power mechanism; 200. a mixing and extruding mechanism; 300. a granulation mechanism; 400. a pelleting mechanism; 101. a drive motor; 102. a drive pulley; 103. a first support base; 104. a driven pulley; 105. a reduction gearbox; 106. a first reduction gear; 107. a second reduction gear; 108. a third reduction gear; 109. a fourth reduction gear; 110. a drive shaft; 201. a feed hopper; 202. a mixing bin; 203. a second support base; 204. an extrusion die head; 205. a shearing cylinder; 206. a first electric heating fan; 207. a threaded shear bar; 301. a granulating bin; 302. a granulation motor; 303. a grain receiving hopper; 304. a second electric heating fan; 305. a linkage shaft; 306. a driving gear; 307. a driven gear; 308. a cutting knife; 401. a pill making bin; 402. a discharge hopper; 403. a pill storage box; 404. a motor case; 405. a turntable; 406. a transmission gear; 407. a pill making motor.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
referring to fig. 1 to 9, the present embodiment is a process for preparing a traditional Chinese medicine pill for treating urinary calculus, including the following steps:
the method comprises the following steps: pulverizing spora Lygodii, endothelium corneum Gigeriae Galli, Alismatis rhizoma, lignum Aquilariae Resinatum, Succinum, semen plantaginis, radix Curcumae, Poria, radix Platycodi, and radix Cyathulae, and sieving with 100 mesh sieve to obtain mixed medicinal powder;
step two: mixing earthworm, scouring rush, cluster mallow seed and liquorice, adding 9 times of water by weight, decocting for 1.2 hours after the water is boiled to obtain a first decoction, adding 7 times of water by weight after the first decoction is poured out, decocting for 1 hour after the water is boiled to obtain a second decoction, adding 5 times of water by weight after the second decoction is poured out, decocting for 1 hour after the water is boiled to obtain a third decoction, combining the first decoction, the second decoction and the third decoction, and filtering to obtain a filtrate;
step three: cooling the filtrate, adding potassium nitrate, stirring uniformly, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain a concentrated solution, starting a power mechanism 100 of the pill production equipment, driving a motor 101 to rotate to realize rotation of a transmission shaft 110, so as to drive a thread shearing rod 207 of a mixing extrusion mechanism 200 to rotate, pouring mixed powder, talcum powder, cane sugar and the concentrated solution into a feed hopper 201, feeding the mixed powder, the talcum powder, the cane sugar and the concentrated solution into a shearing cylinder 205 from the bottom of the feed hopper 201, shearing the mixed powder, the talcum powder, the cane sugar and the concentrated solution through the rotating thread shearing rod 207, uniformly mixing to obtain a mixed raw material, conveying the mixed raw material forward through the rotating thread shearing rod 207, feeding the mixed raw material into an extrusion die head 204, making the mixed raw material into a cylindrical shape through the extrusion die head 204, and starting a granulating motor 302 and a second electric heating fan 304 of, the second electric heating fan 304 releases hot air to dry the cylindrical mixed raw materials to a certain degree and form the cylindrical mixed raw materials, the granulation motor 302 operates to realize the rotation of the universal driving shaft 305 and the cutting knife 308, the rotating cutting knife 308 cuts the cylindrical mixed raw materials into particles and falls into the particle receiving hopper 303, the pill making motor 407 of the pill making mechanism 400 is started, the operation of the pill making motor 407 realizes the rotation of the turntable 405, the granular mixed raw materials enter the pill making bin 401 from the bottom of the particle receiving hopper 303 and fall to the edge of the inner cavity of the rotating turntable 405 to roll in the inner part along with the rotation of the turntable 405, the granular mixed raw materials are rolled to form pills, and the traditional Chinese medicine pills for treating urinary calculus are obtained after being dried.
The traditional Chinese medicine pill for treating urinary calculus is prepared from the following components in parts by weight:
4 parts of climbing fern spore, 2 parts of endothelium corneum gigeriae galli, 4 parts of rhizoma alismatis, 4 parts of lumbricus, 1 part of agilawood, 1 part of amber, 2 parts of potassium nitrate, 4 parts of scouring rush, 8 parts of cluster mallow fruit, 4 parts of semen plantaginis, 4 parts of radix curcumae, 4 parts of poria cocos, 15 parts of talcum powder, 2 parts of liquorice, 4 parts of platycodon grandiflorum, 4 parts of medicinal cyathula root and 8 parts of sucrose.
Example 2:
the difference between the embodiment and the embodiment 1 is that the traditional Chinese medicine pill for treating urinary calculus is prepared from the following components in parts by weight:
6 parts of climbing fern spore, 4 parts of endothelium corneum gigeriae galli, 6 parts of rhizoma alismatis, 6 parts of lumbricus, 2 parts of agilawood, 2 parts of amber, 4 parts of potassium nitrate, 6 parts of scouring rush, 10 parts of cluster mallow fruit, 6 parts of semen plantaginis, 6 parts of radix curcumae, 6 parts of poria cocos, 17 parts of talcum powder, 5 parts of liquorice, 6 parts of platycodon grandiflorum, 6 parts of medicinal cyathula root and 10 parts of sucrose.
Example 3:
the difference between the embodiment and the embodiment 1 is that the traditional Chinese medicine pill for treating urinary calculus is prepared from the following components in parts by weight:
8 parts of climbing fern spore, 6 parts of endothelium corneum gigeriae galli, 8 parts of rhizoma alismatis, 8 parts of lumbricus, 3 parts of agilawood, 3 parts of amber, 6 parts of potassium nitrate, 8 parts of scouring rush, 12 parts of cluster mallow fruit, 8 parts of semen plantaginis, 8 parts of radix curcumae, 8 parts of poria cocos, 19 parts of talcum powder, 7 parts of liquorice, 8 parts of platycodon grandiflorum, 8 parts of medicinal cyathula root and 12 parts of sucrose.
Example 4:
referring to fig. 1 to 9, the pill production apparatus in the present embodiment includes an actuating mechanism 100, a mixing and extruding mechanism 200, a granulating mechanism 300, and a pill making mechanism 400, wherein one end of the actuating mechanism 100 is connected to the mixing and extruding mechanism 200, one end of the mixing and extruding mechanism 200 away from the actuating mechanism 100 is connected to the granulating mechanism 300, and the bottom end of the granulating mechanism 300 is connected to the top of the pill making mechanism 400;
the power mechanism 100 comprises a driving motor 101, a first supporting base 103 and a reduction gearbox 105, wherein the reduction gearbox 105 is installed at the top of the first supporting base 103, a driven belt pulley 104 is installed on one side of the reduction gearbox 105 through a rotating shaft, the driven belt pulley 104 is connected with a driving belt pulley 102 through a belt, and the driving belt pulley 102 is sleeved on an output shaft of the driving motor 101; a first reduction gear 106, a second reduction gear 107, a third reduction gear 108 and a fourth reduction gear 109 are mounted in the inner cavity of the reduction box 105, the driven pulley 104 is connected to the first reduction gear 106 through a rotating shaft, the first reduction gear 106 is in meshed connection with the second reduction gear 107, one end of the second reduction gear 107 is welded with the third reduction gear 108, the second reduction gear 107 and the third reduction gear 108 are mounted to the inner cavity of the reduction box 105 through the rotating shaft, the third reduction gear 108 is in meshed connection with the fourth reduction gear 109, and the fourth reduction gear 109 is sleeved on one end of a transmission shaft 110; wherein, the outer diameters of the first reduction gear 106 and the third reduction gear 108 are smaller than the outer diameter of the second reduction gear 107, and the outer diameter of the third reduction gear 108 is smaller than the outer diameter of the fourth reduction gear 109;
the mixing and extruding mechanism 200 comprises a feed hopper 201, a mixing bin 202, a second supporting base 203 and an extruding die head 204, wherein the feed hopper 201 is installed at one end of the top of the mixing bin 202, the mixing bin 202 is installed at the bottom of the second supporting base 203, a shearing cylinder 205 and a plurality of first electric heating fans 206 are installed in an inner cavity of the mixing bin 202, the bottom of the inner cavity of the shearing cylinder 205 is communicated with the plurality of first electric heating fans 206, the top of one end of the shearing cylinder 205 is communicated with the bottom of the feed hopper 201, the end, away from the feed hopper 201, of the shearing cylinder 205 is provided with the extruding die head 204, and a threaded shearing rod 207 is installed in the inner cavity of the shearing; wherein, the end of the screw thread shearing rod 207 far away from the extrusion die head 204 is connected with the end of the transmission shaft 110 far away from the fourth reduction gear 109;
the granulating mechanism 300 comprises a granulating bin 301, a granulating motor 302, a granule receiving hopper 303 and a second electric heating fan 304, wherein the granulating motor 302 is installed on one side surface of the granulating bin 301 in a penetrating manner, the granule receiving hopper 303 is installed at the bottom of the granulating bin 301, one side of the granulating bin 301 is communicated to the second electric heating fan 304 through a pipeline, a linkage shaft 305 is rotatably installed on a longitudinal central line of one side surface of the granulating bin 301 through a bearing, a driven gear 307 is sleeved on the linkage shaft 305, a driving gear 306 is sleeved on an output shaft of the granulating motor 302, the driving gear 306 is meshed with the driven gear 307, and a cutting knife 308 is sleeved at one end, far away from the driven gear 307, of the linkage shaft 305; the side, far away from the granulating motor 302, of the granulating bin 301 is sleeved at the end part of the mixing bin 202, the cutting knife 308 is in contact with the end part of the extrusion die head 204, and the second electric heating fan 304 is installed at the top of the pelletizing mechanism 400;
the pelleting mechanism 400 comprises a pelleting bin 401, a discharge hopper 402, a pill storage box 403 and a motor box 404, wherein the pill storage box 403 is installed in an inner cavity at the bottom of the pelleting bin 401, the top of the pill storage box 403 is communicated to the bottom of the discharge hopper 402, the discharge hopper 402 is installed on the pelleting bin 401 in a penetrating manner, the motor box 404 is arranged at one side of the pill storage box 403 at the bottom of the pelleting bin 401, a turntable 405 is installed in the inner cavity at the top of the pelleting bin 401 in a rotating manner through a bearing, a rodent is arranged on the side surface of the turntable 405, a transmission gear 406 is meshed and connected to one side of the turntable 405, the transmission gear 406 is sleeved on an output shaft of a pelleting motor 407, and the pelleting motor 407 is installed in; the height of the outer edge of the rotary disc 405 is larger than that of the circle center, a discharge port is formed in the circle center of the rotary disc 405, and the discharge port is communicated with the top of the discharge hopper 402.
Referring to fig. 1 to 9, the operation process of the pill production equipment in this embodiment for producing traditional Chinese medicine pills for treating urinary calculus is as follows:
the method comprises the following steps: starting a driving motor 101 of the power mechanism 100, wherein the driving motor 101 drives a first reduction gear 106 to rotate through a driving belt pulley 102 and a driven belt pulley 104, so as to sequentially drive a second reduction gear 107, a third reduction gear 108, a fourth reduction gear 109 and a transmission shaft 110 to rotate, and further drive a thread shearing rod 207 of the mixed material extrusion mechanism 200 to rotate;
step two: pouring the mixed powder, the talcum powder, the sucrose and the concentrated solution into a feed hopper 201 of a mixing extrusion mechanism 200, enabling the mixed powder, the talcum powder, the sucrose and the concentrated solution to enter a shearing barrel 205 from the bottom of the feed hopper 201, shearing the mixed powder, the talcum powder, the sucrose and the concentrated solution through a rotating threaded shearing rod 207, uniformly mixing to obtain a mixed raw material, conveying the mixed raw material forwards through the rotating threaded shearing rod 207, enabling the mixed raw material to enter an extrusion die head 204, and enabling the mixed raw material to pass through the extrusion die head 204 to be cylindrical;
step three: starting a granulating motor 302 and a second electric heating fan 304 of the granulating mechanism 300, wherein the second electric heating fan 304 releases hot air to dry and shape the cylindrical mixed raw material to a certain extent, the granulating motor 302 drives a linkage shaft 305 and a cutting knife 308 to rotate through a driving gear 306 and a driven gear 307, and the rotating cutting knife 308 cuts the cylindrical mixed raw material into particles and falls into a particle receiving hopper 303;
step four: the pelleting motor 407 of the pelleting mechanism 400 is started, the pelleting motor 407 operates to drive the transmission gear 406 to rotate, so as to drive the turntable 405 to rotate, the granular mixed raw materials enter the pelleting bin 401 from the bottom of the pelleting hopper 303, fall to the edge of the inner cavity of the rotating turntable 405, roll in the rotating turntable 405 along with the rotation of the turntable 405, and roll in the inner part of the rotating turntable to form pills;
step five: the turntable 405 stops rotating, the pill-shaped mixed raw materials roll to the circle center of the turntable 405, are discharged from the circle center of the turntable 405 to the pill storage tank 403 through the discharge hopper 402 for storage, and are dried to obtain the traditional Chinese medicine pill for treating urinary calculus.
And (3) verification of curative effect:
the traditional Chinese medicine pill for treating the urinary calculus, which is prepared according to the embodiment of the invention, is 3 +/-1% g of weight of each pill and is taken orally 3 times a day. 324 patients with urinary calculus are randomly selected, after the medicine is taken for a period of time, the symptoms are obviously improved or cured effectively, and the effective rates reach 94.6 percent respectively. Wherein, curing: b ultrasonic shows that calculus is discharged, and clinical symptoms such as urinary system obstruction and infection such as lumbago, angina, hematuria, frequent micturition, urgent micturition and odynuria disappear; the symptoms are obviously improved: b ultrasonic shows that the stone grains are reduced, and the clinical symptoms are relieved; and (4) invalidation: the type-B ultrasonic showed no change in the calculi, and the above clinical symptoms were not alleviated.
Typical cases are as follows:
aligning with a certain part: the male, 22 years old, Zhengzhou city of Henan province, detected urinary calculus in 2018 in 9 months, accompanied by symptoms of frequent micturition, urgent micturition and odynuria, the symptoms of frequent micturition, urgent micturition and odynuria are relieved after taking the medicine for 7 days, the B-ultrasonic examination of 1 menstruation obviously improves, and the male is cured after taking the medicine for 3 months.
Money is given: the male, 53 years old, Zhejiang Hangzhou city, 2019, detected urinary calculus in 4 months, accompanied by symptoms of lumbago, colic, hematuria and odynuria, the symptoms of hematuria and odynuria were relieved after 5 days of administration, 3 months of administration were obviously improved through B-ultrasonic examination, and the male was cured after half a year of administration.
Wu, Wu: female, 38 years old, Anhui province, Hefei city people, examined urinary calculus in 2019 in 8 months with symptoms of hematuria and odynuria, the symptoms of hematuria and odynuria were relieved after taking the medicine for 10 days, the symptoms of hematuria and odynuria were obviously improved after B-ultrasonic examination after taking the medicine for 2 months, and the patient was cured after taking the medicine for 4 months.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.

Claims (7)

1. A preparation process of a traditional Chinese medicine pill for treating urinary calculus is characterized by comprising the following steps:
the method comprises the following steps: pulverizing spora Lygodii, endothelium corneum Gigeriae Galli, Alismatis rhizoma, lignum Aquilariae Resinatum, Succinum, semen plantaginis, radix Curcumae, Poria, radix Platycodi, and radix Cyathulae, and sieving with 100 mesh sieve to obtain mixed medicinal powder;
step two: mixing earthworm, scouring rush, cluster mallow seed and liquorice, adding 8-10 times of water by weight, decocting for 1.2 hours after the water is boiled to obtain a first decoction, adding 6-8 times of water by weight after the first decoction is poured out, decocting for 1 hour after the water is boiled to obtain a second decoction, adding 4-6 times of water by weight after the second decoction is poured out, decocting for 1 hour after the water is boiled to obtain a third decoction, combining the first decoction, the second decoction and the third decoction, and filtering to obtain a filtrate;
step three: adding the potassium nitrate into the cooled filtrate, uniformly stirring, completely dissolving the potassium nitrate, filtering, heating and concentrating to obtain a concentrated solution, starting a power mechanism (100) of pill production equipment, driving a motor (101) to rotate to realize rotation of a transmission shaft (110), so as to drive a thread shearing rod (207) of a mixing extrusion mechanism (200) to rotate, pouring mixed medicinal powder, talcum powder, cane sugar and the concentrated solution into a feed hopper (201), feeding the mixed medicinal powder, the talcum powder, the cane sugar and the concentrated solution into a shearing cylinder (205) from the bottom of the feed hopper (201), shearing the mixed medicinal powder, the talcum powder, the cane sugar and the concentrated solution through the rotating thread shearing rod (207), uniformly mixing to obtain a mixed raw material, conveying the mixed raw material forwards through the rotating thread shearing rod (207), feeding the mixed raw material into an extrusion die head (204), and making the mixed raw material into a cylindrical shape through the extrusion die head (204), starting a granulating motor (302) and a second electric heating fan (304) of the granulating mechanism (300), wherein the second electric heating fan (304) releases hot air to dry and shape the cylindrical mixed raw material to a certain extent, the rotation of a linkage shaft (305) and a cutting knife (308) is realized by the operation of the granulating motor (302), the cylindrical mixed raw material is cut into particles by the rotating cutting knife (308), and the particles fall into a particle receiving hopper (303), the pelleting motor (407) of the pelleting mechanism (400) is started, the pelleting motor (407) operates to realize the rotation of the turntable (405), the granular mixed raw materials enter the pelleting bin (401) from the bottom of the pelleting hopper (303), falls to the inner cavity edge of the rotating turntable (405), and along with the rotation of the turntable (405), rolling the mixture in the container to form pills, and drying to obtain the final product.
2. The preparation process of the traditional Chinese medicine pill for treating the urinary calculus as claimed in claim 1, which is characterized in that the traditional Chinese medicine pill for treating the urinary calculus is prepared from the following components in parts by weight:
4-8 parts of lygodium japonicum, 2-6 parts of endothelium corneum gigeriae galli, 4-8 parts of rhizoma alismatis, 4-8 parts of lumbricus, 1-3 parts of agilawood, 1-3 parts of amber, 2-6 parts of potassium nitrate, 4-8 parts of scouring rush, 8-12 parts of cluster mallow fruit, 4-8 parts of semen plantaginis, 4-8 parts of radix curcumae, 4-8 parts of poria cocos, 15-19 parts of talcum powder, 2-7 parts of liquorice, 4-8 parts of platycodon grandiflorum, 4-8 parts of medicinal cyathula root and 8-12 parts of cane sugar.
3. The preparation process of the traditional Chinese medicine pill for treating the urinary calculus according to claim 1, wherein the power mechanism (100) comprises a driving motor (101), a first supporting base (103) and a reduction gearbox (105), the reduction gearbox (105) is installed at the top of the first supporting base (103), a driven belt pulley (104) is installed on one side of the reduction gearbox (105) through a rotating shaft, the driven belt pulley (104) is connected with a driving belt pulley (102) through a belt, and the driving belt pulley (102) is sleeved on an output shaft of the driving motor (101); install first reduction gear (106), second reduction gear (107), third reduction gear (108), fourth reduction gear (109) in reducing gear box (105) inner chamber, driven pulley (104) are connected to first reduction gear (106) through the pivot, second reduction gear (107) are connected in first reduction gear (106) meshing, third reduction gear (108) have been welded to second reduction gear (107) one end, second reduction gear (107), third reduction gear (108) are installed to reducing gear box (105) inner chamber through the pivot, fourth reduction gear (109) are connected in third reduction gear (108) meshing, fourth reduction gear (109) cup joint is served in one of transmission shaft (110).
4. The preparation process of the Chinese medicinal pill for treating urinary calculus according to claim 1, it is characterized in that the mixing and extruding mechanism (200) comprises a feed hopper (201), a mixing bin (202), a second supporting base (203) and an extruding die head (204), the feed hopper (201) is arranged at one end of the top of the mixing bin (202), the mixing bin (202) is arranged at the bottom of the second supporting base (203), a shearing cylinder (205) and a plurality of first electric heating fans (206) are arranged in the inner cavity of the mixing bin (202), the bottom of the inner cavity of the shearing cylinder (205) is communicated with a plurality of first electric heating fans (206), shearing section of thick bamboo (205) one end top and feeder hopper (201) bottom intercommunication, shearing section of thick bamboo (205) are kept away from feeder hopper (201) one end and are installed extrusion die (204), install screw thread shear bar (207) in shearing section of thick bamboo (205) inner chamber.
5. The preparation process of the Chinese medicinal pill for treating urinary calculus according to claim 1, it is characterized in that the granulating mechanism (300) comprises a granulating bin (301), a granulating motor (302), a granule receiving hopper (303) and a second electric heating fan (304), a granulation motor (302) is arranged on one side surface of the granulation bin (301) in a penetrating way, a granulation receiving hopper (303) is arranged at the bottom of the granulation bin (301), one side of the granulating bin (301) is communicated to a second electric heating fan (304) through a pipeline, a linkage shaft (305) is rotatably arranged on a longitudinal central line of one side surface of the granulating bin (301) through a bearing, a driven gear (307) is sleeved on the linkage shaft (305), a driving gear (306) is sleeved on an output shaft of the granulating motor (302), the driving gear (306) is meshed with the driven gear (307), and one end, far away from the driven gear (307), of the linkage shaft (305) is sleeved with a cutting knife (308).
6. The preparation process of the traditional Chinese medicine pill for treating urinary calculus according to claim 1, wherein the pill making mechanism (400) comprises a pill making bin (401), a discharge hopper (402), a pill storage bin (403) and a motor box (404), the pill storage bin (403) is installed in an inner cavity at the bottom of the pill making bin (401), the top of the pill storage bin (403) is communicated to the bottom of the discharge hopper (402), the discharge hopper (402) is installed on the pill making bin (401) in a penetrating manner, the motor box (404) is arranged at one side of the pill storage bin (403) at the bottom of the pill making bin (401), a turntable (405) is installed in an inner cavity at the top of the pill making bin (401) in a rotating manner through a bearing, a rodent is arranged on the side surface of the turntable (405), a transmission gear (406) is meshed and connected to one side of the turntable (405), the transmission gear (406) is sleeved on an output shaft of a pill making, the pelleting motor (407) is arranged in the inner cavity of the motor box (404).
7. The preparation process of the traditional Chinese medicine pill for treating urinary calculus according to claim 1, wherein the pill production equipment in step three produces the traditional Chinese medicine pill for treating urinary calculus in the following working process:
the method comprises the following steps: starting a driving motor (101) of the power mechanism (100), wherein the driving motor (101) runs to drive a first reduction gear (106) to rotate through a driving belt pulley (102) and a driven belt pulley (104), so that a second reduction gear (107), a third reduction gear (108), a fourth reduction gear (109) and a transmission shaft (110) are sequentially driven to rotate, and a thread shearing rod (207) of the mixing extrusion mechanism (200) is driven to rotate;
step two: pouring the mixed powder, the talcum powder, the sucrose and the concentrated solution into a feed hopper (201) of a mixing extrusion mechanism (200), enabling the mixed powder, the talcum powder, the sucrose and the concentrated solution to enter a shearing barrel (205) from the bottom of the feed hopper (201), shearing the mixed powder, the talcum powder, the sucrose and the concentrated solution through a rotating thread shearing rod (207), uniformly mixing to obtain a mixed raw material, conveying the mixed raw material forwards through the rotating thread shearing rod (207), enabling the mixed raw material to enter an extrusion die head (204), and enabling the mixed raw material to pass through the extrusion die head (204) to be cylindrical;
step three: starting a granulating motor (302) and a second electric heating fan (304) of the granulating mechanism (300), wherein the second electric heating fan (304) releases hot air to dry and shape the cylindrical mixed raw material to a certain extent, the granulating motor (302) rotates to drive a linkage shaft (305) and a cutting knife (308) to rotate through a driving gear (306) and a driven gear (307), and the cylindrical mixed raw material is cut into particles by the rotating cutting knife (308) and falls into a particle receiving hopper (303);
step four: starting a pelleting motor (407) of the pelleting mechanism (400), wherein the pelleting motor (407) operates to drive a transmission gear (406) to rotate so as to drive a turntable (405) to rotate, and granular mixed raw materials enter a pelleting bin (401) from the bottom of a pelleting hopper (303), fall to the edge of an inner cavity of the rotating turntable (405), roll in the rotary hopper along with the rotation of the turntable (405), and roll to form pills;
step five: the rotary table (405) stops rotating, the pill-shaped mixed raw materials roll to the circle center of the rotary table (405), are discharged from the circle center of the rotary table (405) to the pill storage tank (403) through the discharge hopper (402) for storage, and are dried to obtain the traditional Chinese medicine pill for treating the urinary calculus.
CN202010921726.4A 2020-09-04 2020-09-04 Preparation process of traditional Chinese medicine pills for treating urinary calculus Pending CN111888445A (en)

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